Experiment set14S704 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Sodium phosphite dibasic pentahydrate 100 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS02280 -5.7 -1.1 DUF211 domain-containing protein compare
MMP_RS08210 -5.6 -2.9 phosphatidylglycerophosphatase A compare
MMP_RS03315 -5.1 -1.7 ferrous iron transport protein A compare
MMP_RS01005 -4.9 -1.3 riboflavin synthase compare
MMP_RS08300 -4.8 -1.6 metal-sulfur cluster assembly factor compare
MMP_RS01755 -4.6 -1.3 DUF2097 domain-containing protein compare
MMP_RS00300 -4.5 -0.9 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS05920 -4.4 -0.8 50S ribosomal protein L37e compare
MMP_RS01020 -4.4 -1.2 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06230 -4.3 -4.2 helix-turn-helix domain-containing protein compare
MMP_RS01380 -4.2 -5.7 PHP domain-containing protein compare
MMP_RS03580 -4.1 -4.3 signal recognition particle-docking protein FtsY compare
MMP_RS08715 -3.9 -2.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06730 -3.8 -2.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS02240 -3.7 -3.7 methanogenesis marker 7 protein compare
MMP_RS06120 -3.7 -3.2 UPF0147 family protein compare
MMP_RS01175 -3.7 -3.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS07380 -3.7 -2.8 transcription elongation factor Spt5 compare
MMP_RS08460 -3.5 -3.0 proteasome-activating nucleotidase compare
MMP_RS06630 -3.5 -1.0 UPF0058 family protein compare
MMP_RS02175 -3.5 -1.2 DUF1611 domain-containing protein compare
MMP_RS02900 -3.4 -0.9 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS08820 -3.4 -5.3 hypothetical protein compare
MMP_RS05515 -3.4 -6.9 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06975 -3.4 -2.6 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS04685 -3.3 -4.1 DUF126 domain-containing protein compare
MMP_RS06895 -3.3 -1.8 selenocysteine-specific translation elongation factor compare
MMP_RS01610 -3.3 -3.1 hypothetical protein compare
MMP_RS00685 -3.3 -4.1 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07625 -3.3 -4.9 cobalt ECF transporter T component CbiQ compare
MMP_RS07635 -3.2 -7.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07600 -3.2 -2.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06680 -3.2 -9.9 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03435 -3.2 -2.4 ketol-acid reductoisomerase compare
MMP_RS06295 -3.1 -6.0 methanogenesis marker 14 protein compare
MMP_RS00110 -3.1 -3.6 hypothetical protein compare
MMP_RS08645 -3.0 -7.3 UPF0179 family protein compare
MMP_RS03600 -3.0 -3.1 triose-phosphate isomerase compare
MMP_RS01500 -3.0 -2.7 CBS domain-containing protein compare
MMP_RS07005 -3.0 -0.8 4Fe-4S binding protein compare
MMP_RS08720 -3.0 -1.6 4Fe-4S binding protein compare
MMP_RS06685 -2.9 -9.6 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS00895 -2.9 -5.0 hypothetical protein compare
MMP_RS04710 -2.9 -2.3 hypothetical protein compare
MMP_RS08790 -2.8 -3.1 translation initiation factor IF-2 subunit alpha compare
MMP_RS01225 -2.8 -5.7 DUF5379 domain-containing protein compare
MMP_RS06355 -2.8 -2.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS07445 -2.8 -6.1 helix-turn-helix domain-containing protein compare
MMP_RS01795 -2.7 -2.0 methanogenesis marker 6 protein compare
MMP_RS05845 -2.7 -2.4 tRNA-intron lyase compare
MMP_RS06345 -2.7 -7.7 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS02875 -2.7 -12.4 chorismate pyruvate-lyase family protein compare
MMP_RS06020 -2.7 -5.1 archaeoflavoprotein AfpA compare
MMP_RS06700 -2.7 -12.1 hypothetical protein compare
MMP_RS07525 -2.7 -7.6 4Fe-4S binding protein compare
MMP_RS06110 -2.6 -4.6 ATP-dependent protease LonB compare
MMP_RS03015 -2.6 -7.9 GTP 3' 8-cyclase MoaA compare
MMP_RS05430 -2.6 -2.8 TIGR00288 family NYN domain-containing protein compare
MMP_RS03960 -2.6 -1.1 hypothetical protein compare
MMP_RS08635 -2.6 -2.0 UbiA family prenyltransferase compare
MMP_RS04585 -2.6 -8.0 AIR synthase related protein compare
MMP_RS06350 -2.5 -6.4 HesA/MoeB/ThiF family protein compare
MMP_RS03555 -2.5 -10.4 transcriptional regulator compare
MMP_RS06400 -2.5 -1.6 4Fe-4S binding protein compare
MMP_RS04775 -2.5 -4.1 adenosylhomocysteinase compare
MMP_RS00130 -2.4 -1.5 nickel-responsive transcriptional regulator NikR compare
MMP_RS00115 -2.4 -11.1 radical SAM protein compare
MMP_RS07605 -2.4 -4.0 diadenylate cyclase compare
MMP_RS06285 -2.4 -2.2 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS06625 -2.4 -2.3 DNA primase compare
MMP_RS07615 -2.4 -6.8 energy-coupling factor ABC transporter permease compare
MMP_RS06475 -2.4 -4.9 FAD-dependent oxidoreductase compare
MMP_RS07425 -2.3 -5.8 GTP-binding protein compare
MMP_RS06340 -2.3 -5.8 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00125 -2.3 -1.8 DUF2798 domain-containing protein compare
MMP_RS03035 -2.2 -4.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS04870 -2.1 -5.3 TIGR02253 family HAD-type hydrolase compare
MMP_RS00305 -2.1 -2.4 phosphoribosyl-ATP diphosphatase compare
MMP_RS01800 -2.1 -3.0 TIGR00303 family protein compare
MMP_RS06855 -2.0 -9.1 hypothetical protein compare
MMP_RS03640 -2.0 -3.6 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS03445 -2.0 -1.2 methanogenesis marker 17 protein compare
MMP_RS01385 -2.0 -0.8 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS04890 -2.0 -1.0 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS07750 -2.0 -5.4 DUF357 domain-containing protein compare
MMP_RS07620 -2.0 -5.1 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS00695 -2.0 -0.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS03400 -1.9 -2.4 archease compare
MMP_RS00515 -1.9 -1.1 DUF655 domain-containing protein compare
MMP_RS06720 -1.9 -7.0 response regulator transcription factor compare
MMP_RS08745 -1.8 -4.5 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS05865 -1.8 -2.5 hypothetical protein compare
MMP_RS00675 -1.8 -1.1 nitroreductase family protein compare
MMP_RS06105 -1.8 -5.1 hydrogenase maturation peptidase HycI compare
MMP_RS07350 -1.8 -2.0 preprotein translocase subunit Sec61beta compare
MMP_RS01325 -1.8 -1.8 dihydroneopterin aldolase family protein compare
MMP_RS06175 -1.8 -6.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS02800 -1.8 -5.1 nucleotidyltransferase domain-containing protein compare
MMP_RS07200 -1.7 -5.0 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05925 -1.7 -2.7 small nuclear ribonucleoprotein compare
MMP_RS06270 -1.7 -3.6 TIGR00300 family protein compare
MMP_RS05550 -1.7 -0.8 cation:proton antiporter compare
MMP_RS06715 -1.7 -11.5 cache domain-containing protein compare
MMP_RS01985 -1.7 -4.4 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS05250 -1.7 -3.3 NFYB/HAP3 family transcription factor subunit compare
MMP_RS02165 -1.7 -6.2 tRNA-dihydrouridine synthase compare
MMP_RS01980 -1.6 -10.4 trimeric intracellular cation channel family protein compare
MMP_RS01220 -1.6 -4.8 hypothetical protein compare
MMP_RS08435 -1.6 -2.0 Era-like GTP-binding protein compare
MMP_RS06885 -1.6 -2.2 50S ribosome-binding GTPase compare
MMP_RS01830 -1.6 -1.4 tRNA-Val compare
MMP_RS01335 -1.6 -2.8 prefoldin subunit beta compare
MMP_RS09020 -1.5 -1.2 hypothetical protein compare
MMP_RS05545 -1.5 -6.4 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS04485 -1.5 -9.0 putative beta-lysine N-acetyltransferase compare
MMP_RS07075 -1.5 -3.2 phosphomannomutase/phosphoglucomutase compare
MMP_RS02355 -1.5 -2.0 30S ribosomal protein S27ae compare
MMP_RS03025 -1.5 -3.7 molybdenum cofactor guanylyltransferase compare
MMP_RS04480 -1.4 -8.9 lysine 2 3-aminomutase compare
MMP_RS00915 -1.4 -4.7 DUF116 domain-containing protein compare
MMP_RS00900 -1.4 -1.9 50S ribosomal protein L39e compare
MMP_RS07765 -1.4 -6.6 sodium:alanine symporter family protein compare
MMP_RS07685 -1.4 -5.2 TIGR01212 family radical SAM protein compare
MMP_RS07580 -1.4 -1.9 DUF356 domain-containing protein compare
MMP_RS05510 -1.4 -4.0 Rrf2 family transcriptional regulator compare
MMP_RS05540 -1.4 -1.9 hypothetical protein compare
MMP_RS03305 -1.4 -6.4 winged helix-turn-helix domain-containing protein compare
MMP_RS03205 -1.4 -1.4 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS04780 -1.4 -1.5 ribonuclease P compare
MMP_RS01365 -1.4 -3.0 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS06200 -1.3 -6.1 M24 family metallopeptidase compare
MMP_RS07330 -1.3 -10.5 membrane protein compare
MMP_RS00040 -1.3 -4.5 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS05245 -1.3 -6.8 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS01250 -1.3 -3.2 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS07575 -1.3 -2.9 RNA ligase partner protein compare
MMP_RS00810 -1.3 -4.2 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07420 -1.3 -4.0 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01545 -1.3 -1.0 CBS domain-containing protein compare
MMP_RS02195 -1.3 -2.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07755 -1.3 -1.0 DUF555 domain-containing protein compare
MMP_RS05850 -1.2 -2.9 Ldh family oxidoreductase compare
MMP_RS00720 -1.2 -6.0 metal-dependent hydrolase compare
MMP_RS02135 -1.2 -2.1 DUF5612 domain-containing protein compare
MMP_RS06395 -1.2 -2.4 ThiF family adenylyltransferase compare
MMP_RS03095 -1.2 -4.3 diphthine synthase compare
MMP_RS07390 -1.2 -1.7 cell division protein FtsZ compare
MMP_RS07365 -1.2 -7.2 2-phosphoglycerate kinase compare
MMP_RS07775 -1.2 -5.0 alanine dehydrogenase compare
MMP_RS04955 -1.2 -2.6 DNA topoisomerase I compare
MMP_RS06215 -1.1 -2.6 30S ribosomal protein S6e compare
MMP_RS00320 -1.1 -1.5 class I SAM-dependent methyltransferase compare
MMP_RS01265 -1.1 -1.5 hypothetical protein compare
MMP_RS07845 -1.1 -1.2 LL-diaminopimelate aminotransferase compare
MMP_RS00730 -1.1 -3.3 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS08600 -1.1 -1.9 flagellar protein D compare
MMP_RS02245 -1.1 -1.9 hypothetical protein compare
MMP_RS07730 -1.1 -1.2 pyruvate synthase subunit beta compare
MMP_RS08095 -1.1 -4.9 dethiobiotin synthase compare
MMP_RS01840 -1.1 -5.0 TIGR00289 family protein compare
MMP_RS00555 -1.1 -3.3 MFS transporter compare
MMP_RS01700 -1.1 -0.9 dihydroxy-acid dehydratase compare
MMP_RS08200 -1.1 -8.1 archaeosine synthase subunit alpha compare
MMP_RS00290 -1.1 -4.7 hypothetical protein compare
MMP_RS06015 -1.0 -4.1 flavodoxin family protein compare
MMP_RS02930 -1.0 -1.6 class I SAM-dependent methyltransferase compare
MMP_RS06930 -1.0 -5.8 MBL fold metallo-hydrolase compare
MMP_RS08940 -1.0 -1.2 MetS family NSS transporter small subunit compare
MMP_RS05355 -1.0 -0.8 hypothetical protein compare
MMP_RS00295 -1.0 -1.6 gamma carbonic anhydrase family protein compare
MMP_RS05635 -1.0 -5.0 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS00050 -1.0 -5.2 AarF/UbiB family protein compare
MMP_RS01195 -1.0 -1.0 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS08650 -1.0 -1.3 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS06840 -1.0 -0.8 DNA-directed RNA polymerase subunit N compare
MMP_RS04875 -1.0 -3.9 energy-converting hydrogenase B subunit P compare
MMP_RS05765 -1.0 -3.2 M42 family metallopeptidase compare
MMP_RS00520 -1.0 -0.7 RNA polymerase Rpb4 family protein compare
MMP_RS03120 -1.0 -2.4 hypothetical protein compare
MMP_RS05080 -1.0 -6.0 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS02595 -1.0 -1.1 putative zinc-binding protein compare
MMP_RS05285 -1.0 -3.2 MMPL family transporter compare
MMP_RS08605 -0.9 -2.9 flagellar protein E compare
MMP_RS01665 -0.9 -2.1 DUF2111 domain-containing protein compare
MMP_RS05095 -0.9 -3.9 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS07875 -0.9 -3.5 hypothetical protein compare
MMP_RS01720 -0.9 -1.1 replication factor C large subunit compare
MMP_RS05835 -0.9 -0.6 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS00620 -0.9 -3.3 4Fe-4S binding protein compare
MMP_RS01495 -0.9 -5.4 TraB/GumN family protein compare
MMP_RS00325 -0.9 -1.4 RNA-binding protein compare
MMP_RS06865 -0.9 -1.0 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS03385 -0.9 -0.8 cation diffusion facilitator family transporter compare
MMP_RS06725 -0.9 -3.9 hypothetical protein compare
MMP_RS03020 -0.9 -3.0 peptidylprolyl isomerase compare
MMP_RS02145 -0.9 -3.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS07545 -0.9 -0.8 HTH domain-containing protein compare
MMP_RS05640 -0.9 -3.2 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS05085 -0.9 -5.0 AAA family ATPase compare
MMP_RS02235 -0.8 -3.8 CBS domain-containing protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium phosphite dibasic pentahydrate across organisms