Experiment set14S702 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS00520		-6.6	-1.6	RNA polymerase Rpb4 family protein
MMP_RS05930		-6.3	-2.0	3-isopropylmalate dehydratase large subunit
MMP_RS09025		-6.2	-0.9	hypothetical protein
MMP_RS01545		-5.9	-0.9	CBS domain-containing protein
MMP_RS03435		-5.6	-1.6	ketol-acid reductoisomerase
MMP_RS07555		-5.1	-0.7	monovalent cation/H+ antiporter subunit E
MMP_RS05835		-5.0	-0.7	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS08370		-4.4	-0.6	cation:proton antiporter subunit C
MMP_RS02900		-4.4	-0.6	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS03315		-4.4	-1.1	ferrous iron transport protein A
MMP_RS00515		-4.2	-0.9	DUF655 domain-containing protein
MMP_RS03475		-4.0	-0.6	hypothetical protein
MMP_RS00305		-2.8	-1.7	phosphoribosyl-ATP diphosphatase
MMP_RS01720		-2.7	-1.9	replication factor C large subunit
MMP_RS03205		-2.6	-1.1	peptidyl-tRNA hydrolase Pth2
MMP_RS08785		-2.6	-0.8	RNA-protein complex protein Nop10
MMP_RS04685		-2.6	-1.8	DUF126 domain-containing protein
MMP_RS02805		-2.5	-1.1	HEPN domain-containing protein
MMP_RS08650		-2.4	-2.2	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS05355		-2.2	-0.7	hypothetical protein
MMP_RS05845		-2.0	-1.1	tRNA-intron lyase
MMP_RS00830		-1.9	-2.0	purine phosphoribosyltransferase family protein
MMP_RS01795		-1.9	-1.1	methanogenesis marker 6 protein
MMP_RS00685		-1.8	-1.8	2-phospho-L-lactate guanylyltransferase
MMP_RS06110		-1.6	-1.6	ATP-dependent protease LonB
MMP_RS00110		-1.6	-1.7	hypothetical protein
MMP_RS07845		-1.6	-0.8	LL-diaminopimelate aminotransferase
MMP_RS01460		-1.5	-2.6	hypothetical protein
MMP_RS02955		-1.5	-2.0	DJ-1/PfpI family protein
MMP_RS06215		-1.5	-1.4	30S ribosomal protein S6e
MMP_RS07390		-1.5	-1.2	cell division protein FtsZ
MMP_RS00895		-1.5	-1.7	hypothetical protein
MMP_RS06230		-1.4	-1.1	helix-turn-helix domain-containing protein
MMP_RS04015		-1.4	-0.9	hypothetical protein
MMP_RS03305		-1.4	-2.9	winged helix-turn-helix domain-containing protein
MMP_RS05865		-1.3	-2.1	hypothetical protein
MMP_RS02745		-1.3	-1.0	hypothetical protein
MMP_RS03640		-1.3	-0.9	archaeal proteasome endopeptidase complex subunit beta
MMP_RS07435		-1.3	-0.8	GMP synthase subunit A
MMP_RS03400		-1.3	-0.7	archease
MMP_RS03120		-1.3	-1.9	hypothetical protein
MMP_RS07775		-1.2	-2.0	alanine dehydrogenase
MMP_RS04195		-1.1	-1.5	flavodoxin
MMP_RS08265		-1.1	-1.2	rubrerythrin
MMP_RS00750		-1.1	-0.7	fumarate hydratase
MMP_RS08435		-1.1	-1.0	Era-like GTP-binding protein
MMP_RS08440		-1.1	-1.2	cell division protein SepF
MMP_RS01445		-1.1	-1.6	hypothetical protein
MMP_RS02490		-1.0	-1.1	hypothetical protein
MMP_RS00730		-1.0	-1.8	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS04870		-1.0	-1.6	TIGR02253 family HAD-type hydrolase
MMP_RS03350		-1.0	-1.3	winged helix-turn-helix domain-containing protein
MMP_RS03600		-1.0	-0.8	triose-phosphate isomerase
MMP_RS06975		-1.0	-0.4	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS07755		-1.0	-0.5	DUF555 domain-containing protein
MMP_RS04360		-0.9	-1.4	hypothetical protein
MMP_RS06585		-0.9	-0.8	DMT family protein
MMP_RS06155		-0.9	-1.1	DUF4186 domain-containing protein
MMP_RS08790		-0.9	-1.0	translation initiation factor IF-2 subunit alpha
MMP_RS06840		-0.9	-0.5	DNA-directed RNA polymerase subunit N
MMP_RS05020		-0.9	-1.3	hypothetical protein
MMP_RS08750		-0.9	-1.9	hypothetical protein
MMP_RS08620		-0.9	-2.1	flagellar accessory protein FlaH
MMP_RS06325		-0.9	-0.7	hypothetical protein
MMP_RS07385		-0.9	-1.0	protein translocase SEC61 complex subunit gamma
MMP_RS07605		-0.9	-0.8	diadenylate cyclase
MMP_RS01685		-0.8	-1.3	indolepyruvate oxidoreductase subunit beta
MMP_RS06745		-0.8	-1.4	DUF2119 domain-containing protein
MMP_RS04775		-0.8	-0.8	adenosylhomocysteinase
MMP_RS07805		-0.8	-2.1	ABC transporter permease
MMP_RS07625		-0.8	-1.0	cobalt ECF transporter T component CbiQ
MMP_RS06475		-0.8	-0.9	FAD-dependent oxidoreductase
MMP_RS08460		-0.8	-0.5	proteasome-activating nucleotidase
MMP_RS07640		-0.8	-1.7	mechanosensitive ion channel family protein
MMP_RS05955		-0.8	-1.0	CoB--CoM heterodisulfide reductase subunit C
MMP_RS06625		-0.8	-0.4	DNA primase
MMP_RS01265		-0.8	-0.5	hypothetical protein
MMP_RS04485		-0.8	-3.9	putative beta-lysine N-acetyltransferase
MMP_RS08415		-0.8	-1.3	radical SAM protein
MMP_RS05965		-0.8	-1.2	carboxymuconolactone decarboxylase family protein
MMP_RS06435		-0.8	-2.1	CBS domain-containing protein
MMP_RS01655		-0.7	-1.4	DsrE family protein
MMP_RS00450		-0.7	-0.7	4Fe-4S binding protein
MMP_RS08745		-0.7	-1.2	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS05060		-0.7	-2.6	AAA family ATPase
MMP_RS05430		-0.7	-1.8	TIGR00288 family NYN domain-containing protein
MMP_RS00855		-0.7	-1.5	DUF367 family protein
MMP_RS00900		-0.7	-0.8	50S ribosomal protein L39e
MMP_RS03035		-0.7	-0.7	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS06395		-0.7	-0.9	ThiF family adenylyltransferase
MMP_RS08975		-0.7	-1.0	hypothetical protein
MMP_RS02170		-0.7	-1.1	CBS domain-containing protein
MMP_RS00665		-0.7	-1.3	hypothetical protein
MMP_RS07115		-0.7	-3.0	MBL fold metallo-hydrolase
MMP_RS07425		-0.7	-1.6	GTP-binding protein
MMP_RS08645		-0.6	-1.6	UPF0179 family protein
MMP_RS07770		-0.6	-1.8	alanine racemase
MMP_RS02390		-0.6	-0.8	NifB/NifX family molybdenum-iron cluster-binding protein
MMP_RS02235		-0.6	-1.9	CBS domain-containing protein
MMP_RS08930		-0.6	-0.6	hypothetical protein
MMP_RS02025		-0.6	-2.9	DNA-directed DNA polymerase
MMP_RS02300		-0.6	-1.9	NAD(P)H-dependent oxidoreductase
MMP_RS05765		-0.6	-1.4	M42 family metallopeptidase
MMP_RS02315		-0.6	-1.3	RimK family alpha-L-glutamate ligase
MMP_RS05700		-0.6	-1.9	TfuA-related McrA-glycine thioamidation protein
MMP_RS08500		-0.6	-1.7	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
MMP_RS05435		-0.6	-2.8	5'/3'-nucleotidase SurE
MMP_RS00185		-0.6	-2.8	potassium channel protein
MMP_RS02190		-0.6	-0.8	sulfopyruvate decarboxylase subunit alpha
MMP_RS05425		-0.6	-0.7	monovalent cation/H+ antiporter complex subunit F
MMP_RS07575		-0.6	-0.7	RNA ligase partner protein
MMP_RS05125		-0.5	-1.7	D-aminoacyl-tRNA deacylase
MMP_RS03860		-0.5	-1.6	hypothetical protein
MMP_RS07880		-0.5	-2.3	AAA family ATPase
MMP_RS05545		-0.5	-1.0	pyridoxal phosphate-dependent aminotransferase
MMP_RS08615		-0.5	-0.8	flagellar protein G
MMP_RS07355		-0.5	-0.3	transcription factor S
MMP_RS02405		-0.5	-1.5	hypothetical protein
MMP_RS05070		-0.5	-1.4	4Fe-4S dicluster domain-containing protein
MMP_RS06865		-0.5	-0.9	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS00760		-0.5	-1.6	branched-chain-amino-acid transaminase
MMP_RS03140		-0.5	-1.8	hypothetical protein
MMP_RS02550		-0.5	-1.0	helix-turn-helix transcriptional regulator
MMP_RS03330		-0.5	-2.6	rubrerythrin family protein
MMP_RS00535		-0.5	-0.7	TIGR00375 family protein
MMP_RS06875		-0.5	-1.7	FAD-dependent oxidoreductase
MMP_RS06035		-0.5	-1.5	glycosyltransferase family 2 protein
MMP_RS04475		-0.5	-1.4	nitrogen fixation
MMP_RS00240		-0.5	-2.2	type II secretion system F family protein
MMP_RS01985		-0.5	-1.0	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS08945		-0.5	-1.9	hypothetical protein
MMP_RS07125		-0.5	-0.7	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS02995		-0.5	-1.2	acyl-CoA thioesterase
MMP_RS00295		-0.5	-0.6	gamma carbonic anhydrase family protein
MMP_RS02380		-0.5	-1.5	ATP-binding protein
MMP_RS00320		-0.5	-0.4	class I SAM-dependent methyltransferase
MMP_RS05175		-0.5	-1.3	hypothetical protein
MMP_RS08400		-0.5	-1.2	MJ0307 family thioredoxin
MMP_RS01215		-0.5	-1.5	sodium/proline symporter PutP
MMP_RS03470		-0.5	-1.2	phosphoadenosine phosphosulfate reductase family protein
MMP_RS04215		-0.5	-1.4	nickel pincer cofactor biosynthesis protein LarB
MMP_RS02675		-0.5	-0.6	hypothetical protein
MMP_RS02495		-0.4	-0.5	hypothetical protein
MMP_RS08570		-0.4	-1.7	coenzyme F420-0:L-glutamate ligase
MMP_RS02815		-0.4	-0.7	hypothetical protein
MMP_RS02425		-0.4	-1.4	hypothetical protein
MMP_RS02110		-0.4	-0.3	hypothetical protein
MMP_RS01625		-0.4	-2.2	rubredoxin
MMP_RS06185		-0.4	-1.0	thermonuclease family protein
MMP_RS08770		-0.4	-1.5	hypothetical protein
MMP_RS06605		-0.4	-2.0	DUF5814 domain-containing protein
MMP_RS02690		-0.4	-0.9	FmdE family protein
MMP_RS03535		-0.4	-0.8	helix-turn-helix transcriptional regulator
MMP_RS05635		-0.4	-1.2	NAD-dependent epimerase/dehydratase family protein
MMP_RS08200		-0.4	-2.3	archaeosine synthase subunit alpha
MMP_RS00475		-0.4	-1.5	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS01620		-0.4	-0.5	hypothetical protein
MMP_RS08990		-0.4	-1.0	hypothetical protein
MMP_RS03815		-0.4	-1.4	excinuclease ABC subunit UvrA
MMP_RS06300		-0.4	-1.4	ABC transporter substrate-binding protein
MMP_RS01575		-0.4	-1.6	aldolase
MMP_RS08580		-0.4	-0.9	flagellin
MMP_RS04785		-0.4	-2.2	hypothetical protein
MMP_RS01165		-0.4	-0.7	DUF434 domain-containing protein
MMP_RS03555		-0.4	-1.3	transcriptional regulator
MMP_RS04850		-0.4	-2.2	UPF0254 family protein
MMP_RS07615		-0.4	-0.9	energy-coupling factor ABC transporter permease
MMP_RS06270		-0.4	-0.7	TIGR00300 family protein
MMP_RS00310		-0.4	-1.5	CBS domain-containing protein
MMP_RS06200		-0.4	-1.4	M24 family metallopeptidase
MMP_RS05575		-0.4	-1.7	hypothetical protein
MMP_RS07700		-0.4	-1.4	DUF1188 domain-containing protein
MMP_RS05595		-0.4	-1.8	imidazole glycerol phosphate synthase subunit HisH
MMP_RS05960		-0.4	-1.5	CoB--CoM heterodisulfide reductase subunit B
MMP_RS06725		-0.4	-1.1	hypothetical protein
MMP_RS03745		-0.4	-1.3	phenylacetate--CoA ligase
MMP_RS04255		-0.4	-1.1	coenzyme F420 hydrogenase subunit beta
MMP_RS08755		-0.4	-1.7	sodium:solute symporter family protein
MMP_RS07380		-0.4	-0.4	transcription elongation factor Spt5
MMP_RS08160		-0.4	-1.1	EamA family transporter
MMP_RS05940		-0.4	-1.1	corrinoid protein
MMP_RS02740		-0.4	-0.5	hypothetical protein
MMP_RS04270		-0.4	-1.3	coenzyme F420 hydrogenase subunit alpha
MMP_RS05315		-0.4	-0.4	hypothetical protein
MMP_RS03780		-0.4	-0.8	4Fe-4S binding protein
MMP_RS08405		-0.4	-1.2	MFS transporter
MMP_RS02545		-0.4	-0.9	hypothetical protein
MMP_RS03450		-0.4	-0.3	glycine synthesis protein GlyXS (from data)
MMP_RS04480		-0.4	-2.1	lysine 2 3-aminomutase
MMP_RS02625		-0.4	-1.3	ribonuclease H-like domain-containing protein
MMP_RS01280		-0.4	-2.2	DUF515 domain-containing protein
MMP_RS03960		-0.4	-0.2	hypothetical protein
MMP_RS01090		-0.4	-1.7	ABC transporter substrate-binding protein
MMP_RS04790		-0.4	-1.1	4-hydroxy-tetrahydrodipicolinate reductase
MMP_RS06010		-0.3	-1.6	heavy metal translocating P-type ATPase
MMP_RS03270		-0.3	-0.8	ADP-ribosylglycohydrolase family protein
MMP_RS01070		-0.3	-1.8	hypothetical protein
MMP_RS03390		-0.3	-0.9	malate dehydrogenase
MMP_RS04040		-0.3	-1.2	hypothetical protein
MMP_RS04065		-0.3	-1.7	hypothetical protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress mercury (II) chloride across organisms