Experiment set14S699 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Spiramycin 0.1 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS06625 -4.8 -1.9 DNA primase compare
MMP_RS03315 -4.7 -1.2 ferrous iron transport protein A compare
MMP_RS02900 -4.7 -0.7 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS06400 -4.6 -1.6 4Fe-4S binding protein compare
MMP_RS07860 -4.6 -0.7 hypothetical protein compare
MMP_RS01005 -4.5 -0.9 riboflavin synthase compare
MMP_RS07755 -4.5 -0.9 DUF555 domain-containing protein compare
MMP_RS08790 -4.4 -2.2 translation initiation factor IF-2 subunit alpha compare
MMP_RS06215 -4.4 -2.7 30S ribosomal protein S6e compare
MMP_RS01755 -4.3 -0.9 DUF2097 domain-containing protein compare
MMP_RS02240 -4.2 -3.0 methanogenesis marker 7 protein compare
MMP_RS07005 -4.2 -0.6 4Fe-4S binding protein compare
MMP_RS01610 -4.1 -2.8 hypothetical protein compare
MMP_RS01225 -4.0 -5.5 DUF5379 domain-containing protein compare
MMP_RS03960 -4.0 -0.8 hypothetical protein compare
MMP_RS03600 -3.7 -2.2 triose-phosphate isomerase compare
MMP_RS07605 -3.5 -2.5 diadenylate cyclase compare
MMP_RS08715 -3.4 -1.7 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06355 -3.4 -2.1 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS04585 -3.4 -8.8 AIR synthase related protein compare
MMP_RS03205 -3.3 -1.4 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS05550 -3.3 -0.7 cation:proton antiporter compare
MMP_RS01500 -3.2 -1.8 CBS domain-containing protein compare
MMP_RS05515 -3.2 -5.8 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS07525 -3.2 -7.2 4Fe-4S binding protein compare
MMP_RS06630 -3.2 -0.7 UPF0058 family protein compare
MMP_RS03015 -3.1 -10.6 GTP 3' 8-cyclase MoaA compare
MMP_RS08300 -3.1 -1.1 metal-sulfur cluster assembly factor compare
MMP_RS06925 -3.0 -2.0 ribonuclease VapC4 compare
MMP_RS07445 -3.0 -6.6 helix-turn-helix domain-containing protein compare
MMP_RS04685 -3.0 -2.9 DUF126 domain-containing protein compare
MMP_RS06350 -3.0 -5.3 HesA/MoeB/ThiF family protein compare
MMP_RS03640 -2.9 -3.2 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS00305 -2.9 -1.7 phosphoribosyl-ATP diphosphatase compare
MMP_RS01020 -2.8 -0.8 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS03400 -2.8 -1.8 archease compare
MMP_RS06840 -2.8 -0.9 DNA-directed RNA polymerase subunit N compare
MMP_RS04890 -2.8 -0.8 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS07635 -2.8 -5.8 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS02145 -2.7 -7.7 winged helix-turn-helix transcriptional regulator compare
MMP_RS08820 -2.7 -4.0 hypothetical protein compare
MMP_RS03035 -2.6 -3.9 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01985 -2.6 -5.7 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS04710 -2.6 -1.5 hypothetical protein compare
MMP_RS02165 -2.6 -7.5 tRNA-dihydrouridine synthase compare
MMP_RS00850 -2.6 -5.8 TIGR01177 family methyltransferase compare
MMP_RS06685 -2.6 -7.5 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS01250 -2.6 -6.0 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS00300 -2.6 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS08635 -2.6 -1.9 UbiA family prenyltransferase compare
MMP_RS06295 -2.6 -5.7 methanogenesis marker 14 protein compare
MMP_RS07685 -2.6 -9.2 TIGR01212 family radical SAM protein compare
MMP_RS03580 -2.6 -2.8 signal recognition particle-docking protein FtsY compare
MMP_RS01325 -2.6 -1.7 dihydroneopterin aldolase family protein compare
MMP_RS06680 -2.5 -9.5 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03435 -2.5 -1.3 ketol-acid reductoisomerase compare
MMP_RS06855 -2.5 -8.8 hypothetical protein compare
MMP_RS06345 -2.5 -9.2 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS08645 -2.5 -7.0 UPF0179 family protein compare
MMP_RS05865 -2.5 -2.2 hypothetical protein compare
MMP_RS07845 -2.4 -1.3 LL-diaminopimelate aminotransferase compare
MMP_RS02010 -2.4 -8.6 PHP domain-containing protein compare
MMP_RS07750 -2.4 -4.7 DUF357 domain-containing protein compare
MMP_RS00320 -2.4 -1.5 class I SAM-dependent methyltransferase compare
MMP_RS01175 -2.3 -2.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06975 -2.3 -1.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS01840 -2.3 -9.6 TIGR00289 family protein compare
MMP_RS07200 -2.3 -5.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS04780 -2.3 -2.8 ribonuclease P compare
MMP_RS06110 -2.3 -3.1 ATP-dependent protease LonB compare
MMP_RS06730 -2.3 -1.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS08720 -2.3 -1.1 4Fe-4S binding protein compare
MMP_RS01365 -2.3 -3.1 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS08535 -2.3 -8.1 bis-aminopropyl spermidine synthase family protein conserved
MMP_RS00130 -2.2 -1.0 nickel-responsive transcriptional regulator NikR compare
MMP_RS05765 -2.2 -4.1 M42 family metallopeptidase compare
MMP_RS07425 -2.2 -6.3 GTP-binding protein compare
MMP_RS03025 -2.2 -4.4 molybdenum cofactor guanylyltransferase compare
MMP_RS05845 -2.2 -1.6 tRNA-intron lyase compare
MMP_RS07615 -2.1 -4.6 energy-coupling factor ABC transporter permease compare
MMP_RS07625 -2.1 -3.2 cobalt ECF transporter T component CbiQ compare
MMP_RS03475 -2.1 -0.5 hypothetical protein compare
MMP_RS03095 -2.1 -4.8 diphthine synthase compare
MMP_RS02875 -2.1 -7.1 chorismate pyruvate-lyase family protein compare
MMP_RS06340 -2.0 -5.9 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00295 -2.0 -1.6 gamma carbonic anhydrase family protein compare
MMP_RS07620 -2.0 -4.2 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS08595 -2.0 -1.1 flagellar protein C compare
MMP_RS06175 -2.0 -5.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS01380 -2.0 -3.2 PHP domain-containing protein compare
MMP_RS00895 -2.0 -2.8 hypothetical protein compare
MMP_RS03555 -2.0 -5.6 transcriptional regulator compare
MMP_RS04775 -1.9 -2.7 adenosylhomocysteinase compare
MMP_RS06270 -1.9 -4.3 TIGR00300 family protein compare
MMP_RS02195 -1.9 -2.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS03445 -1.9 -0.8 methanogenesis marker 17 protein compare
MMP_RS01265 -1.9 -2.6 hypothetical protein compare
MMP_RS07365 -1.9 -9.2 2-phosphoglycerate kinase compare
MMP_RS07630 -1.9 -1.4 ATP-binding cassette domain-containing protein compare
MMP_RS01545 -1.8 -0.8 CBS domain-containing protein compare
MMP_RS00110 -1.8 -2.3 hypothetical protein compare
MMP_RS05925 -1.8 -2.6 small nuclear ribonucleoprotein compare
MMP_RS02190 -1.8 -2.3 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS02340 -1.8 -2.1 DNA-directed RNA polymerase subunit E'' compare
MMP_RS07535 -1.8 -8.5 4Fe-4S binding protein compare
MMP_RS01195 -1.8 -0.9 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06020 -1.8 -2.8 archaeoflavoprotein AfpA compare
MMP_RS02175 -1.7 -0.7 DUF1611 domain-containing protein compare
MMP_RS00050 -1.7 -3.9 AarF/UbiB family protein compare
MMP_RS00735 -1.7 -4.3 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS05020 -1.7 -3.4 hypothetical protein compare
MMP_RS00695 -1.7 -0.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS08460 -1.6 -1.6 proteasome-activating nucleotidase compare
MMP_RS01385 -1.6 -0.5 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS03590 -1.6 -6.5 METTL5 family protein compare
MMP_RS03145 -1.6 -3.6 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS00730 -1.6 -5.0 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS07600 -1.6 -1.6 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS01980 -1.6 -8.9 trimeric intracellular cation channel family protein compare
MMP_RS06315 -1.6 -0.6 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS02235 -1.6 -6.5 CBS domain-containing protein compare
MMP_RS01800 -1.6 -2.3 TIGR00303 family protein compare
MMP_RS06200 -1.6 -6.6 M24 family metallopeptidase compare
MMP_RS05635 -1.5 -6.7 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS01220 -1.5 -3.7 hypothetical protein compare
MMP_RS07580 -1.5 -2.2 DUF356 domain-containing protein compare
MMP_RS07700 -1.5 -6.5 DUF1188 domain-containing protein compare
MMP_RS06285 -1.5 -0.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS04090 -1.5 -2.3 hypothetical protein compare
MMP_RS06395 -1.5 -2.5 ThiF family adenylyltransferase compare
MMP_RS05930 -1.5 -1.4 3-isopropylmalate dehydratase large subunit compare
MMP_RS08105 -1.5 -4.5 6-carboxyhexanoate--CoA ligase compare
MMP_RS08210 -1.5 -1.2 phosphatidylglycerophosphatase A compare
MMP_RS01335 -1.5 -1.9 prefoldin subunit beta compare
MMP_RS02345 -1.5 -2.2 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS04305 -1.5 -1.7 hypothetical protein compare
MMP_RS05250 -1.5 -2.8 NFYB/HAP3 family transcription factor subunit compare
MMP_RS07545 -1.5 -0.7 HTH domain-containing protein compare
MMP_RS00725 -1.4 -5.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS01700 -1.4 -0.6 dihydroxy-acid dehydratase compare
MMP_RS04870 -1.4 -2.8 TIGR02253 family HAD-type hydrolase compare
MMP_RS06885 -1.4 -1.8 50S ribosome-binding GTPase compare
MMP_RS01495 -1.4 -6.7 TraB/GumN family protein compare
MMP_RS07530 -1.4 -5.1 4Fe-4S binding protein compare
MMP_RS06980 -1.4 -4.8 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS02355 -1.4 -1.5 30S ribosomal protein S27ae compare
MMP_RS03305 -1.4 -3.4 winged helix-turn-helix domain-containing protein compare
MMP_RS01445 -1.3 -3.9 hypothetical protein compare
MMP_RS08860 -1.3 -3.6 MinD/ParA family protein compare
MMP_RS05295 -1.3 -6.7 minichromosome maintenance protein MCM compare
MMP_RS01720 -1.3 -0.9 replication factor C large subunit compare
MMP_RS04850 -1.3 -8.1 UPF0254 family protein compare
MMP_RS01280 -1.3 -6.9 DUF515 domain-containing protein compare
MMP_RS08095 -1.3 -4.4 dethiobiotin synthase compare
MMP_RS09020 -1.2 -0.8 hypothetical protein compare
MMP_RS06700 -1.2 -6.2 hypothetical protein compare
MMP_RS08615 -1.2 -1.5 flagellar protein G compare
MMP_RS00335 -1.2 -2.9 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH compare
MMP_RS01305 -1.2 -8.9 hypothetical protein compare
MMP_RS04015 -1.2 -1.4 hypothetical protein compare
MMP_RS06720 -1.2 -3.3 response regulator transcription factor compare
MMP_RS03250 -1.2 -2.4 MJ1244 family protein compare
MMP_RS03140 -1.2 -4.3 hypothetical protein compare
MMP_RS07645 -1.2 -3.9 aldehyde dehydrogenase family protein compare
MMP_RS05580 -1.2 -8.0 glycosyltransferase compare
MMP_RS08605 -1.2 -3.4 flagellar protein E compare
MMP_RS05540 -1.2 -1.7 hypothetical protein compare
MMP_RS00115 -1.2 -5.1 radical SAM protein compare
MMP_RS00040 -1.2 -3.9 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS02780 -1.2 -6.0 hypothetical protein compare
MMP_RS07330 -1.1 -8.2 membrane protein compare
MMP_RS08570 -1.1 -5.6 coenzyme F420-0:L-glutamate ligase compare
MMP_RS06120 -1.1 -1.1 UPF0147 family protein compare
MMP_RS04955 -1.1 -2.4 DNA topoisomerase I compare
MMP_RS05280 -1.1 -5.2 COG1361 S-layer family protein compare
MMP_RS02800 -1.1 -3.0 nucleotidyltransferase domain-containing protein compare
MMP_RS06035 -1.1 -4.4 glycosyltransferase family 2 protein compare
MMP_RS05430 -1.1 -3.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS06475 -1.1 -1.6 FAD-dependent oxidoreductase compare
MMP_RS08845 -1.1 -5.0 archaellum operon transcriptional activator EarA family protein compare
MMP_RS06290 -1.1 -2.4 DNA repair and recombination protein RadA compare
MMP_RS06930 -1.1 -5.6 MBL fold metallo-hydrolase compare
MMP_RS00620 -1.1 -4.0 4Fe-4S binding protein compare
MMP_RS07575 -1.1 -2.3 RNA ligase partner protein compare
MMP_RS07695 -1.1 -5.0 DUF3236 domain-containing protein compare
MMP_RS05875 -1.1 -1.7 hydroxyethylthiazole kinase compare
MMP_RS08225 -1.1 -5.8 RimK family alpha-L-glutamate ligase compare
MMP_RS05440 -1.1 -4.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS08610 -1.1 -5.7 flagellar protein F compare
MMP_RS00915 -1.1 -2.7 DUF116 domain-containing protein compare
MMP_RS05800 -1.1 -3.4 B12-binding domain-containing radical SAM protein compare
MMP_RS04500 -1.1 -6.6 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS08445 -1.0 -2.5 DUF2099 family protein compare
MMP_RS05545 -1.0 -3.5 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02135 -1.0 -2.5 DUF5612 domain-containing protein compare
MMP_RS00555 -1.0 -3.3 MFS transporter compare
MMP_RS00685 -1.0 -1.4 2-phospho-L-lactate guanylyltransferase compare
MMP_RS00290 -1.0 -2.9 hypothetical protein compare
MMP_RS01415 -1.0 -2.2 DUF2067 domain-containing protein compare
MMP_RS02955 -1.0 -1.7 DJ-1/PfpI family protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress Spiramycin in Methanococcus maripaludis S2

For stress Spiramycin across organisms