Experiment set14S686 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Chlorpromazine hydrochloride 0.0333333333333333

200 most important genes:

  gene name fitness t score description  
MMP_RS01020 -5.9 -1.0 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS02280 -5.7 -1.0 DUF211 domain-containing protein compare
MMP_RS04780 -5.2 -3.5 ribonuclease P compare
MMP_RS05845 -5.0 -2.4 tRNA-intron lyase compare
MMP_RS02900 -4.9 -0.9 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS06400 -4.9 -2.0 4Fe-4S binding protein compare
MMP_RS08635 -4.6 -2.8 UbiA family prenyltransferase compare
MMP_RS06895 -4.6 -1.9 selenocysteine-specific translation elongation factor compare
MMP_RS08715 -4.6 -2.2 formylmethanofuran dehydrogenase subunit B compare
MMP_RS00300 -4.4 -0.8 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06230 -4.3 -3.6 helix-turn-helix domain-containing protein compare
MMP_RS01175 -4.2 -3.0 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03315 -4.1 -1.7 ferrous iron transport protein A compare
MMP_RS06625 -4.0 -2.4 DNA primase compare
MMP_RS08820 -3.8 -7.3 hypothetical protein compare
MMP_RS07600 -3.8 -2.8 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS01225 -3.8 -4.4 DUF5379 domain-containing protein compare
MMP_RS06285 -3.7 -2.5 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS08460 -3.7 -2.7 proteasome-activating nucleotidase compare
MMP_RS08300 -3.6 -1.5 metal-sulfur cluster assembly factor compare
MMP_RS00695 -3.5 -0.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS03445 -3.4 -1.2 methanogenesis marker 17 protein compare
MMP_RS01800 -3.4 -4.4 TIGR00303 family protein compare
MMP_RS01610 -3.3 -2.9 hypothetical protein compare
MMP_RS03435 -3.2 -2.2 ketol-acid reductoisomerase compare
MMP_RS06110 -3.2 -3.2 ATP-dependent protease LonB compare
MMP_RS07635 -3.1 -6.8 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07755 -3.1 -1.2 DUF555 domain-containing protein compare
MMP_RS00320 -3.0 -2.0 class I SAM-dependent methyltransferase compare
MMP_RS06295 -3.0 -7.4 methanogenesis marker 14 protein compare
MMP_RS06700 -2.9 -9.4 hypothetical protein compare
MMP_RS03305 -2.8 -7.4 winged helix-turn-helix domain-containing protein compare
MMP_RS01500 -2.7 -2.3 CBS domain-containing protein compare
MMP_RS03035 -2.7 -4.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS00110 -2.7 -3.3 hypothetical protein compare
MMP_RS05515 -2.7 -6.0 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS03600 -2.7 -2.1 triose-phosphate isomerase compare
MMP_RS07445 -2.7 -6.2 helix-turn-helix domain-containing protein compare
MMP_RS06685 -2.7 -8.5 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS04775 -2.6 -3.5 adenosylhomocysteinase compare
MMP_RS07380 -2.6 -2.2 transcription elongation factor Spt5 compare
MMP_RS05430 -2.6 -4.4 TIGR00288 family NYN domain-containing protein compare
MMP_RS00685 -2.6 -3.7 2-phospho-L-lactate guanylyltransferase compare
MMP_RS09020 -2.6 -1.7 hypothetical protein compare
MMP_RS04685 -2.6 -3.0 DUF126 domain-containing protein compare
MMP_RS06355 -2.5 -2.7 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01005 -2.5 -1.1 riboflavin synthase compare
MMP_RS01325 -2.5 -2.5 dihydroneopterin aldolase family protein compare
MMP_RS07620 -2.5 -5.3 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS03015 -2.5 -7.7 GTP 3' 8-cyclase MoaA compare
MMP_RS06975 -2.4 -2.0 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS06680 -2.4 -7.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS04585 -2.4 -9.6 AIR synthase related protein compare
MMP_RS06350 -2.3 -5.4 HesA/MoeB/ThiF family protein compare
MMP_RS03640 -2.3 -2.2 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS08720 -2.3 -1.3 4Fe-4S binding protein compare
MMP_RS08790 -2.3 -2.4 translation initiation factor IF-2 subunit alpha compare
MMP_RS07005 -2.3 -0.7 4Fe-4S binding protein compare
MMP_RS07545 -2.3 -1.1 HTH domain-containing protein compare
MMP_RS07525 -2.3 -5.9 4Fe-4S binding protein compare
MMP_RS03205 -2.3 -1.7 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS07615 -2.2 -6.8 energy-coupling factor ABC transporter permease compare
MMP_RS06345 -2.2 -6.9 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS01335 -2.2 -2.7 prefoldin subunit beta compare
MMP_RS04710 -2.2 -1.9 hypothetical protein compare
MMP_RS00895 -2.1 -3.8 hypothetical protein compare
MMP_RS02165 -2.1 -7.3 tRNA-dihydrouridine synthase compare
MMP_RS01380 -2.1 -3.8 PHP domain-containing protein compare
MMP_RS05865 -2.1 -4.5 hypothetical protein compare
MMP_RS06120 -2.1 -2.1 UPF0147 family protein compare
MMP_RS05525 -2.0 -7.7 calcium/sodium antiporter compare
MMP_RS08645 -2.0 -6.4 UPF0179 family protein compare
MMP_RS05550 -2.0 -0.8 cation:proton antiporter compare
MMP_RS06730 -2.0 -1.7 phosphopantothenate/pantothenate synthetase compare
MMP_RS00305 -2.0 -1.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS02175 -2.0 -1.0 DUF1611 domain-containing protein compare
MMP_RS06020 -2.0 -4.6 archaeoflavoprotein AfpA compare
MMP_RS03025 -2.0 -4.1 molybdenum cofactor guanylyltransferase compare
MMP_RS08650 -2.0 -2.8 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS06175 -2.0 -6.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS02875 -1.9 -8.0 chorismate pyruvate-lyase family protein compare
MMP_RS00810 -1.9 -6.4 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07555 -1.9 -0.8 monovalent cation/H+ antiporter subunit E compare
MMP_RS06105 -1.8 -5.1 hydrogenase maturation peptidase HycI compare
MMP_RS00115 -1.8 -9.9 radical SAM protein compare
MMP_RS03110 -1.8 -5.0 glycosyltransferase family 2 protein compare
MMP_RS07625 -1.8 -2.6 cobalt ECF transporter T component CbiQ compare
MMP_RS08210 -1.8 -1.6 phosphatidylglycerophosphatase A compare
MMP_RS06340 -1.8 -5.8 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS05920 -1.8 -0.6 50S ribosomal protein L37e compare
MMP_RS02800 -1.8 -6.9 nucleotidyltransferase domain-containing protein compare
MMP_RS01795 -1.7 -1.2 methanogenesis marker 6 protein compare
MMP_RS03555 -1.7 -6.3 transcriptional regulator compare
MMP_RS03580 -1.7 -2.9 signal recognition particle-docking protein FtsY compare
MMP_RS07605 -1.7 -2.2 diadenylate cyclase compare
MMP_RS06725 -1.7 -6.0 hypothetical protein compare
MMP_RS05815 -1.7 -2.0 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS07390 -1.7 -2.2 cell division protein FtsZ compare
MMP_RS06630 -1.6 -0.8 UPF0058 family protein compare
MMP_RS00735 -1.6 -4.5 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS02195 -1.6 -2.9 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS08595 -1.6 -1.2 flagellar protein C compare
MMP_RS06270 -1.6 -4.2 TIGR00300 family protein compare
MMP_RS07630 -1.6 -1.7 ATP-binding cassette domain-containing protein compare
MMP_RS01985 -1.6 -3.2 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS07735 -1.6 -0.7 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS01365 -1.6 -2.5 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS00730 -1.6 -4.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS00130 -1.6 -1.2 nickel-responsive transcriptional regulator NikR compare
MMP_RS01755 -1.5 -1.1 DUF2097 domain-containing protein compare
MMP_RS07365 -1.5 -8.0 2-phosphoglycerate kinase compare
MMP_RS07200 -1.5 -4.0 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS08745 -1.5 -4.5 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS00295 -1.4 -1.7 gamma carbonic anhydrase family protein compare
MMP_RS04870 -1.4 -3.6 TIGR02253 family HAD-type hydrolase compare
MMP_RS07425 -1.4 -3.6 GTP-binding protein compare
MMP_RS05545 -1.4 -4.3 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS00040 -1.4 -4.8 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS06015 -1.4 -6.4 flavodoxin family protein compare
MMP_RS00675 -1.4 -0.9 nitroreductase family protein compare
MMP_RS05020 -1.4 -3.1 hypothetical protein compare
MMP_RS05250 -1.4 -2.3 NFYB/HAP3 family transcription factor subunit compare
MMP_RS06855 -1.4 -6.9 hypothetical protein compare
MMP_RS05540 -1.4 -2.5 hypothetical protein compare
MMP_RS01980 -1.3 -8.1 trimeric intracellular cation channel family protein compare
MMP_RS00515 -1.3 -0.9 DUF655 domain-containing protein compare
MMP_RS00060 -1.3 -1.5 3-dehydroquinate synthase II compare
MMP_RS07685 -1.3 -6.3 TIGR01212 family radical SAM protein compare
MMP_RS00725 -1.2 -4.6 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS01700 -1.2 -0.9 dihydroxy-acid dehydratase compare
MMP_RS01250 -1.2 -5.2 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS00915 -1.2 -5.0 DUF116 domain-containing protein compare
MMP_RS01265 -1.2 -1.2 hypothetical protein compare
MMP_RS05295 -1.2 -6.6 minichromosome maintenance protein MCM compare
MMP_RS03475 -1.2 -0.5 hypothetical protein compare
MMP_RS02240 -1.2 -1.7 methanogenesis marker 7 protein compare
MMP_RS03095 -1.2 -4.0 diphthine synthase compare
MMP_RS06290 -1.2 -4.4 DNA repair and recombination protein RadA compare
MMP_RS06840 -1.2 -0.9 DNA-directed RNA polymerase subunit N compare
MMP_RS05265 -1.2 -2.3 2-isopropylmalate synthase compare
MMP_RS05345 -1.2 -3.0 hypothetical protein compare
MMP_RS01495 -1.2 -4.9 TraB/GumN family protein compare
MMP_RS03400 -1.2 -1.7 archease compare
MMP_RS00315 -1.2 -5.0 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS05510 -1.2 -3.8 Rrf2 family transcriptional regulator compare
MMP_RS07385 -1.2 -1.1 protein translocase SEC61 complex subunit gamma compare
MMP_RS00050 -1.1 -4.6 AarF/UbiB family protein compare
MMP_RS00985 -1.1 -3.1 CDC48 family AAA ATPase compare
MMP_RS08675 -1.1 -2.6 class III signal peptide-containing protein compare
MMP_RS03080 -1.1 -1.3 universal stress protein compare
MMP_RS04850 -1.1 -8.0 UPF0254 family protein compare
MMP_RS08435 -1.1 -1.8 Era-like GTP-binding protein compare
MMP_RS06940 -1.1 -1.3 polyprenyl diphosphate synthase compare
MMP_RS01195 -1.1 -0.9 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS09055 -1.1 -0.8 CAP domain-containing protein compare
MMP_RS08570 -1.0 -5.9 coenzyme F420-0:L-glutamate ligase compare
MMP_RS06035 -1.0 -5.4 glycosyltransferase family 2 protein compare
MMP_RS06925 -1.0 -1.6 ribonuclease VapC4 compare
MMP_RS05765 -1.0 -3.8 M42 family metallopeptidase compare
MMP_RS07900 -1.0 -1.4 YeeE/YedE family protein compare
MMP_RS07580 -1.0 -1.9 DUF356 domain-containing protein compare
MMP_RS08095 -1.0 -3.5 dethiobiotin synthase compare
MMP_RS01085 -1.0 -1.4 hypothetical protein compare
MMP_RS03960 -1.0 -0.6 hypothetical protein compare
MMP_RS05415 -1.0 -2.2 DUF22 domain-containing protein compare
MMP_RS06200 -1.0 -4.5 M24 family metallopeptidase compare
MMP_RS06715 -1.0 -5.6 cache domain-containing protein compare
MMP_RS08100 -1.0 -3.8 8-amino-7-oxononanoate synthase compare
MMP_RS04500 -1.0 -6.8 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS06215 -1.0 -1.3 30S ribosomal protein S6e compare
MMP_RS07700 -1.0 -4.7 DUF1188 domain-containing protein compare
MMP_RS00145 -0.9 -5.3 ATP-dependent Clp protease proteolytic subunit compare
MMP_RS00555 -0.9 -3.8 MFS transporter compare
MMP_RS07750 -0.9 -2.3 DUF357 domain-containing protein compare
MMP_RS07695 -0.9 -3.8 DUF3236 domain-containing protein compare
MMP_RS05095 -0.9 -3.8 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS01720 -0.9 -0.7 replication factor C large subunit compare
MMP_RS02345 -0.9 -2.0 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS08230 -0.9 -4.4 50S ribosomal protein L11 methyltransferase compare
MMP_RS04090 -0.9 -2.0 hypothetical protein compare
MMP_RS08940 -0.9 -1.0 MetS family NSS transporter small subunit compare
MMP_RS02815 -0.9 -1.9 hypothetical protein compare
MMP_RS06885 -0.9 -1.1 50S ribosome-binding GTPase compare
MMP_RS03680 -0.9 -4.2 hypothetical protein compare
MMP_RS08200 -0.9 -5.5 archaeosine synthase subunit alpha compare
MMP_RS07575 -0.8 -3.1 RNA ligase partner protein compare
MMP_RS02135 -0.8 -1.7 DUF5612 domain-containing protein compare
MMP_RS00185 -0.8 -6.2 potassium channel protein compare
MMP_RS04980 -0.8 -5.6 DUF2193 domain-containing protein compare
MMP_RS00310 -0.8 -5.1 CBS domain-containing protein compare
MMP_RS06760 -0.8 -1.6 hypothetical protein compare
MMP_RS05060 -0.8 -4.0 AAA family ATPase compare
MMP_RS05635 -0.8 -4.4 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS05800 -0.8 -4.0 B12-binding domain-containing radical SAM protein compare
MMP_RS08370 -0.8 -0.4 cation:proton antiporter subunit C compare
MMP_RS08440 -0.8 -1.4 cell division protein SepF compare
MMP_RS04875 -0.8 -2.2 energy-converting hydrogenase B subunit P compare
MMP_RS06720 -0.8 -3.2 response regulator transcription factor compare
MMP_RS03125 -0.8 -3.0 cell division ATPase MinD compare
MMP_RS00125 -0.8 -0.9 DUF2798 domain-containing protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Chlorpromazine hydrochloride across organisms