Experiment set14S686 for Methanococcus maripaludis S2

200 most detrimental genes:

gene	name	fitness	t score	description
MMP_RS07415		+1.6	7.0	molybdopterin-guanine dinucleotide biosynthesis protein MobB
MMP_RS01885		+1.3	5.2	Gfo/Idh/MocA family oxidoreductase
MMP_RS01370		+1.2	6.5	acetate--CoA ligase family protein
MMP_RS07955		+1.1	4.5	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS01570		+1.1	2.5	hypothetical protein
MMP_RS04605		+1.1	4.4	cobalt ECF transporter T component CbiQ
MMP_RS07820		+1.1	3.0	UPF0104 family protein
MMP_RS07705		+1.0	5.0	transcriptional regulator
MMP_RS05640		+1.0	3.0	UTP--glucose-1-phosphate uridylyltransferase GalU
MMP_RS01960		+1.0	0.7	hypothetical protein
MMP_RS01890		+1.0	2.6	nucleotide sugar dehydrogenase
MMP_RS03485		+1.0	4.0	TIGR00267 family protein
MMP_RS04720		+0.9	2.1	DedA family protein
MMP_RS06575		+0.9	4.1	fluoride efflux transporter CrcB
MMP_RS01910		+0.9	4.5	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
MMP_RS07435		+0.9	1.8	GMP synthase subunit A
MMP_RS01880		+0.8	3.4	DegT/DnrJ/EryC1/StrS family aminotransferase
MMP_RS02290		+0.8	4.4	MBL fold metallo-hydrolase
MMP_RS06670		+0.8	2.1	glucose-6-phosphate isomerase
MMP_RS06555		+0.8	1.4	cupin domain-containing protein
MMP_RS01915		+0.8	4.7	DUF354 domain-containing protein
MMP_RS00450		+0.7	0.9	4Fe-4S binding protein
MMP_RS03420		+0.7	2.6	acetolactate synthase small subunit
MMP_RS01920		+0.7	4.4	glycosyltransferase family 2 protein
MMP_RS00705		+0.7	1.9	hypothetical protein
MMP_RS05695		+0.7	4.4	phospholipase D-like domain-containing protein
MMP_RS02885		+0.7	5.3	molybdopterin biosynthesis protein
MMP_RS06905		+0.7	1.6	hypothetical protein
MMP_RS06325		+0.7	1.2	hypothetical protein
MMP_RS00945		+0.6	1.0	PadR family transcriptional regulator
MMP_RS01900		+0.6	3.8	hypothetical protein
MMP_RS02310		+0.6	1.3	RimK-like ATPgrasp N-terminal domain-containing protein
MMP_RS01970		+0.6	4.1	TIGR04279 domain-containing protein
MMP_RS06190		+0.6	3.0	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
MMP_RS05955		+0.6	1.4	CoB--CoM heterodisulfide reductase subunit C
MMP_RS01875		+0.6	2.9	N-acetyltransferase
MMP_RS01975		+0.6	3.7	hypothetical protein
MMP_RS02880		+0.6	3.8	AmmeMemoRadiSam system radical SAM enzyme
MMP_RS08455		+0.6	2.8	multiprotein bridging factor aMBF1
MMP_RS00750		+0.6	1.1	fumarate hydratase
MMP_RS06310		+0.6	2.1	NAD(P)/FAD-dependent oxidoreductase
MMP_RS04615		+0.6	1.6	PDGLE domain-containing protein
MMP_RS02680		+0.6	2.7	ABC transporter permease
MMP_RS02405		+0.6	2.5	hypothetical protein
MMP_RS03330		+0.6	3.6	rubrerythrin family protein
MMP_RS02605		+0.6	0.6	MotA/TolQ/ExbB proton channel family protein
MMP_RS08275		+0.5	2.9	hypothetical protein
MMP_RS07815		+0.5	0.9	DUF2120 domain-containing protein
MMP_RS01925		+0.5	2.2	DUF1616 domain-containing protein
MMP_RS08390		+0.5	2.4	DUF5400 domain-containing protein
MMP_RS01240		+0.5	0.5	7-cyano-7-deazaguanine synthase QueC
MMP_RS03100		+0.5	2.1	hypothetical protein
MMP_RS05975		+0.5	2.8	hypothetical protein
MMP_RS03150		+0.5	3.5	phosphoglycerate mutase
MMP_RS01905		+0.5	3.2	glycosyltransferase
MMP_RS03340		+0.5	0.6	ABC transporter ATP-binding protein
MMP_RS07960		+0.5	2.8	sugar phosphate isomerase/epimerase
MMP_RS04620		+0.5	2.9	cobalt transporter CbiM
MMP_RS00660		+0.5	3.0	alkaline phosphatase family protein
MMP_RS02905		+0.5	2.5	2-thiouracil desulfurase family protein
MMP_RS08415		+0.5	1.4	radical SAM protein
MMP_RS04695		+0.5	2.1	selenide water dikinase SelD
MMP_RS01065		+0.5	2.7	alpha/beta hydrolase
MMP_RS03675		+0.5	3.4	RimK family alpha-L-glutamate ligase
MMP_RS00740		+0.5	2.0	cyclase family protein
MMP_RS02085		+0.5	3.0	inosine/xanthosine triphosphatase
MMP_RS02870		+0.5	3.0	hypothetical protein
MMP_RS08335		+0.5	2.1	NADH-quinone oxidoreductase subunit B family protein
MMP_RS08215		+0.5	1.5	DUF483 domain-containing protein
MMP_RS04145		+0.5	1.0	hypothetical protein
MMP_RS06365		+0.5	1.0	hypothetical protein
MMP_RS00655		+0.4	1.2	hypothetical protein
MMP_RS03220		+0.4	1.4	RNA 2' 3'-cyclic phosphodiesterase
MMP_RS03440		+0.4	0.6	MoaD/ThiS family protein
MMP_RS07850		+0.4	1.4	prephenate dehydratase
MMP_RS05110		+0.4	2.2	16S ribosomal RNA methyltransferase A
MMP_RS07335		+0.4	1.4	tRNA (cytidine(56)-2'-O)-methyltransferase
MMP_RS07725		+0.4	1.5	4Fe-4S dicluster domain-containing protein
MMP_RS03890		+0.4	1.7	DUF2540 domain-containing protein
MMP_RS03270		+0.4	2.7	ADP-ribosylglycohydrolase family protein
MMP_RS06165		+0.4	2.8	ABC transporter permease
MMP_RS02315		+0.4	2.1	RimK family alpha-L-glutamate ligase
MMP_RS08090		+0.4	2.1	hypothetical protein
MMP_RS05970		+0.4	1.5	class II SORL domain-containing protein
MMP_RS06130		+0.4	1.1	peptidylprolyl isomerase
MMP_RS00670		+0.4	1.8	TIM barrel protein
MMP_RS02965		+0.4	0.8	carboxymuconolactone decarboxylase family protein
MMP_RS01320		+0.4	1.5	hypothetical protein
MMP_RS07915		+0.4	1.4	DUF4870 domain-containing protein
MMP_RS01965		+0.4	2.3	DUF1616 domain-containing protein
MMP_RS00120		+0.4	1.8	LysR family transcriptional regulator
MMP_RS07710		+0.4	1.7	cell division protein FtsZ
MMP_RS01420		+0.4	0.9	hypothetical protein
MMP_RS06570		+0.4	1.2	DUF190 domain-containing protein
MMP_RS07120		+0.4	2.4	coenzyme F420 hydrogenase subunit alpha
MMP_RS06435		+0.4	1.5	CBS domain-containing protein
MMP_RS08310		+0.4	0.8	TMEM165/GDT1 family protein
MMP_RS01895		+0.4	2.0	flippase
MMP_RS08660		+0.4	1.5	DHH family phosphoesterase
MMP_RS03790		+0.4	1.8	hypothetical protein
MMP_RS08315		+0.4	1.3	S-methyl-5-thioribose-1-phosphate isomerase
MMP_RS04830		+0.4	2.8	chemotaxis protein CheC
MMP_RS02790		+0.4	0.5	class III signal peptide-containing protein
MMP_RS08470		+0.4	2.3	ATP-binding cassette domain-containing protein
MMP_RS07180		+0.4	2.4	DEAD/DEAH box helicase
MMP_RS03395		+0.4	1.1	hypothetical protein
MMP_RS08445		+0.4	0.9	DUF2099 family protein
MMP_RS00325		+0.4	0.5	RNA-binding protein
MMP_RS06485		+0.4	0.4	zinc ribbon domain-containing protein
MMP_RS02410		+0.4	0.9	ABC transporter substrate-binding protein
MMP_RS02890		+0.3	1.9	TIGR00296 family protein
MMP_RS02440		+0.3	1.6	hypothetical protein
MMP_RS03335		+0.3	2.2	ABC transporter permease
MMP_RS07835		+0.3	1.2	TldD/PmbA family protein
MMP_RS07100		+0.3	1.8	hypothetical protein
MMP_RS03480		+0.3	2.2	SulP family inorganic anion transporter
MMP_RS01210		+0.3	1.8	sodium:solute symporter
MMP_RS08395		+0.3	1.4	DsrE family protein
MMP_RS01540		+0.3	1.1	DUF504 domain-containing protein
MMP_RS00770		+0.3	1.1	hypothetical protein
MMP_RS03385		+0.3	0.4	cation diffusion facilitator family transporter
MMP_RS06590		+0.3	0.8	GNAT family N-acetyltransferase
MMP_RS05065		+0.3	0.9	CooT family nickel-binding protein
MMP_RS07840		+0.3	1.0	ribonuclease III
MMP_RS07130		+0.3	1.8	coenzyme F420 hydrogenase subunit gamma
MMP_RS03495		+0.3	1.2	Na/Pi cotransporter family protein
MMP_RS05175		+0.3	1.1	hypothetical protein
MMP_RS01525		+0.3	0.7	nucleoside-diphosphate kinase
MMP_RS02145		+0.3	0.9	winged helix-turn-helix transcriptional regulator
MMP_RS06520		+0.3	1.6	DUF1786 domain-containing protein
MMP_RS08500		+0.3	1.1	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
MMP_RS06335		+0.3	1.6	HAD family hydrolase
MMP_RS06185		+0.3	2.0	thermonuclease family protein
MMP_RS01675		+0.3	0.6	hypothetical protein
MMP_RS05355		+0.3	0.3	hypothetical protein
MMP_RS08380		+0.3	1.3	phosphatase PAP2 family protein
MMP_RS06225		+0.3	1.4	DNA double-strand break repair nuclease NurA
MMP_RS00545		+0.3	1.0	XRE family transcriptional regulator
MMP_RS06870		+0.3	0.9	DedA family protein
MMP_RS03215		+0.3	1.8	MBL fold metallo-hydrolase
MMP_RS04495		+0.3	2.0	cation:proton antiporter
MMP_RS01140		+0.3	0.7	molybdate ABC transporter permease subunit
MMP_RS04805		+0.3	2.1	chemotaxis response regulator protein-glutamate methylesterase
MMP_RS03320		+0.3	0.6	metal-dependent transcriptional regulator
MMP_RS08410		+0.3	1.6	DUF169 domain-containing protein
MMP_RS09050		+0.3	1.4	CAP domain-containing protein
MMP_RS08705		+0.3	1.5	sulfopyruvate decarboxylase subunit beta
MMP_RS04835		+0.3	1.6	chemotaxis protein CheC
MMP_RS05560		+0.3	1.3	deoxyuridine 5'-triphosphate nucleotidohydrolase
MMP_RS06535		+0.3	0.7	2-oxoacid:acceptor oxidoreductase family protein
MMP_RS08995		+0.3	0.4	hypothetical protein
MMP_RS01765		+0.3	1.2	HIT family protein
MMP_RS00395		+0.3	0.5	MGMT family protein
MMP_RS08630		+0.3	1.6	archaellar assembly protein FlaJ
MMP_RS05940		+0.3	0.9	corrinoid protein
MMP_RS00345		+0.3	1.1	DUF2666 domain-containing protein
MMP_RS05895		+0.3	1.8	metallophosphoesterase
MMP_RS06060		+0.3	1.5	hypothetical protein
MMP_RS08260		+0.3	1.3	DUF99 family protein
MMP_RS01855		+0.3	1.9	2-hydroxyacyl-CoA dehydratase family protein
MMP_RS01165		+0.3	1.2	DUF434 domain-containing protein
MMP_RS05440		+0.3	1.4	winged helix-turn-helix transcriptional regulator
MMP_RS02985		+0.3	0.8	hypothetical protein
MMP_RS05985		+0.3	0.5	hypothetical protein
MMP_RS01745		+0.3	1.0	AMP phosphorylase
MMP_RS00565		+0.3	0.9	CBS domain-containing protein
MMP_RS02740		+0.3	0.9	hypothetical protein
MMP_RS03990		+0.3	1.3	recombinase family protein
MMP_RS02895		+0.3	1.3	DHH family phosphoesterase
MMP_RS04205		+0.3	1.1	carboxymuconolactone decarboxylase family protein
MMP_RS07925		+0.2	1.1	haloacid dehalogenase
MMP_RS02215		+0.2	1.5	ECF transporter S component
MMP_RS08175		+0.2	1.0	7-cyano-7-deazaguanine synthase
MMP_RS07650		+0.2	1.5	TldD/PmbA family protein
MMP_RS03070		+0.2	0.9	AzlD domain-containing protein
MMP_RS06385		+0.2	0.7	hypothetical protein
MMP_RS06170		+0.2	1.0	ABC transporter ATP-binding protein
MMP_RS06445		+0.2	0.7	DUF89 domain-containing protein
MMP_RS06430		+0.2	0.9	6-carboxytetrahydropterin synthase QueD
MMP_RS00855		+0.2	0.9	DUF367 family protein
MMP_RS03715		+0.2	1.4	class III signal peptide-containing protein
MMP_RS03750		+0.2	1.1	ACT domain-containing protein
MMP_RS01630		+0.2	1.1	N-glycosylase/DNA lyase
MMP_RS00530		+0.2	1.1	tRNA pseudouridine(54/55) synthase Pus10
MMP_RS05675		+0.2	0.6	phosphate ABC transporter ATP-binding protein PstB
MMP_RS01435		+0.2	1.2	DMT family transporter
MMP_RS07890		+0.2	0.6	OB-fold nucleic acid binding domain-containing protein
MMP_RS01620		+0.2	0.7	hypothetical protein
MMP_RS08085		+0.2	1.4	hypothetical protein
MMP_RS08480		+0.2	1.6	molybdate ABC transporter substrate-binding protein
MMP_RS07715		+0.2	1.2	YfcE family phosphodiesterase
MMP_RS07095		+0.2	0.6	PspC domain-containing protein
MMP_RS02745		+0.2	0.6	hypothetical protein
MMP_RS06280		+0.2	1.3	alpha-glucan family phosphorylase
MMP_RS04735		+0.2	1.4	tautomerase family protein
MMP_RS05460		+0.2	1.3	YcaO-related McrA-glycine thioamidation protein
MMP_RS04055		+0.2	0.4	hypothetical protein
MMP_RS08850		+0.2	1.8	hypothetical protein
MMP_RS00380		+0.2	0.7	P-II family nitrogen regulator
MMP_RS01160		+0.2	1.1	DMT family transporter

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Chlorpromazine hydrochloride across organisms