Experiment set14IT042 for Sinorhizobium meliloti 1021

Compare to:

Lactulose carbon source

200 most important genes:

  gene name fitness t score description  
SMc02766 -8.6 -6.0 tryptophan synthase subunit beta compare
SMc01843 -7.7 -9.2 5,10-methylenetetrahydrofolate reductase compare
SMc02572 -7.6 -6.0 imidazole glycerol phosphate synthase subunit HisH compare
SMc02725 -7.5 -7.3 anthranilate synthase compare
SMc00614 -7.4 -5.1 phosphoribosylglycinamide formyltransferase compare
SMc04045 -7.3 -5.1 dihydroxy-acid dehydratase compare
SMc02767 -7.3 -8.7 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc00235 -7.3 -7.1 anthranilate phosphoribosyltransferase compare
SMc04405 -7.2 -8.6 3-isopropylmalate dehydrogenase compare
SMc01726 -7.2 -5.0 acetylglutamate kinase compare
SMc02569 -7.2 -5.0 imidazole glycerol phosphate synthase subunit HisF compare
SMc00917 -7.2 -4.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc02245 -7.1 -4.9 dihydroorotate dehydrogenase 2 compare
SMc00711 -7.0 -4.8 cyclohexadienyl dehydrogenase compare
SMc00236 -6.9 -6.6 Indole-3-glycerol phosphate synthase compare
SMc01494 -6.8 -12.3 phosphoserine phosphatase compare
SMc02217 -6.8 -4.7 O-succinylhomoserine sulfhydrylase compare
SMc02717 -6.8 -9.3 2-isopropylmalate synthase compare
SMc02899 -6.8 -10.4 prephenate dehydratase compare
SMc00131 -6.7 -11.2 transcriptional regulator compare
SMc04028 -6.6 -14.8 glutamate synthase compare
SMc00640 -6.5 -9.9 phosphoserine aminotransferase compare
SMc01431 -6.5 -11.6 acetolactate synthase 3 catalytic subunit compare
SMc03823 -6.4 -11.8 isopropylmalate isomerase large subunit compare
SMc00993 -6.4 -8.8 phosphoribosylamine--glycine ligase compare
SMc00293 -6.4 -11.5 homoserine dehydrogenase compare
SMc03797 -6.3 -11.3 homoserine O-succinyltransferase compare
SMc01054 -6.3 -6.1 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc00488 -6.2 -17.5 phosphoribosylformylglycinamidine synthase II compare
SMc00494 -6.2 -2.5 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMa1635 -6.2 -2.5 hypothetical protein compare
SMc03895 -6.2 -16.5 pyruvate carboxylase compare
SMc00493 -6.1 -5.9 phosphoribosylformylglycinamidine synthase I compare
SMc00882 -6.1 -5.3 2-dehydro-3-deoxy-6-phosphogalactonate aldolase compare
SMc01004 -6.0 -9.5 phosphoribosyl-AMP cyclohydrolase compare
SMc02123 -6.0 -4.2 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc04026 -5.9 -9.6 glutamate synthase compare
SMc03112 -5.9 -16.5 B12-dependent methionine synthase compare
SMc02124 -5.8 -13.6 nitrite reductase compare
SMc00495 -5.8 -5.4 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc02425 -5.8 -5.7 transcriptional regulator compare
SMc01881 -5.8 -4.0 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SMc01361 -5.8 -4.0 dihydroorotase compare
SMc02307 -5.8 -5.6 histidinol dehydrogenase compare
SM_b21655 -5.7 -16.5 Beta-galactosidase (EC 3.2.1.23) (from data) compare
SMc00615 -5.7 -8.1 phosphoribosylaminoimidazole synthetase compare
SMc02765 -5.6 -11.2 tryptophan synthase subunit alpha compare
SMc01801 -5.6 -3.9 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc04002 -5.6 -7.5 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc00091 -5.6 -11.9 sulfate adenylyltransferase compare
SMc02570 -5.5 -6.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc00092 -5.5 -13.3 phosphoadenosine phosphosulfate reductase compare
SMc00918 -5.5 -10.1 ATP phosphoribosyltransferase regulatory subunit compare
SMc00554 -5.4 -9.0 amidophosphoribosyltransferase compare
SMc01360 -5.3 -3.7 aspartate carbamoyltransferase catalytic subunit compare
SMc03763 -5.3 -3.6 cytosine-specific methyltransferase compare
SMc00412 -5.2 -3.6 orotidine 5'-phosphate decarboxylase compare
SMc02755 -5.2 -6.2 S-adenosyl-L-homocysteine hydrolase compare
SMc00090 -5.2 -9.4 sulfate adenylyltransferase compare
SMc02165 -5.1 -5.0 orotate phosphoribosyltransferase compare
SMc03776 -5.1 -3.5 gamma-glutamyl kinase compare
SMc02707 -5.0 -6.7 hypothetical protein compare
SMc04088 -4.9 -8.3 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc00619 -4.9 -3.4 hypothetical protein compare
SMc04001 -4.9 -2.0 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc03777 -4.8 -9.0 gamma-glutamyl phosphate reductase compare
SMc02166 -4.8 -11.5 dihydroorotase compare
SM_b21175 -4.7 -4.4 phosphate uptake ABC transporter permease compare
SM_b21652 -4.5 -12.6 ABC transporter for Lactose, periplasmic substrate-binding component (from data) conserved
SM_b21176 -4.5 -5.3 phosphate uptake ABC transporter substrate-binding protein precursor compare
SM_b20002 -4.3 -11.0 ABC transporter for Lactose, ATPase component (from data) conserved
SMc03979 -4.2 -3.1 glyceraldehyde-3-phosphate dehydrogenase compare
SMc03795 -4.1 -2.3 isopropylmalate isomerase small subunit compare
SMc00815 -4.0 -3.0 inosine 5'-monophosphate dehydrogenase compare
SMc03826 -4.0 -2.7 argininosuccinate synthase compare
SMc02246 -3.9 -1.5 hypothetical protein compare
SMc02164 -3.8 -4.1 fructokinase compare
SMc01053 -3.8 -6.1 siroheme synthase compare
SMc04346 -3.8 -5.1 ketol-acid reductoisomerase compare
SMc01770 -3.8 -1.6 serine hydroxymethyltransferase compare
SM_b21174 -3.8 -5.4 phosphate uptake ABC transporter permease compare
SMc01880 -3.7 -3.6 pantoate--beta-alanine ligase compare
SM_b21654 -3.7 -8.4 ABC transporter for Lactose, permease component 2 (from data) compare
SMc00294 -3.7 -11.2 aminotransferase compare
SMc00017 -3.6 -1.9 homoserine kinase compare
SMc03978 -3.6 -2.5 transketolase compare
SM_b21653 -3.6 -10.0 ABC transporter for Lactose, permease component 1 (from data) conserved
SMc00876 -3.5 -7.8 ATP-binding MRP protein compare
SM_b21177 -3.5 -8.4 phosphate uptake ABC transporter ATP-binding protein compare
SMc01842 -3.4 -3.7 methyltransferase transcription regulator protein compare
SMc02137 -3.4 -4.1 ornithine carbamoyltransferase compare
SMc01215 -3.3 -2.2 carbamoyl phosphate synthase large subunit compare
SMc02138 -3.2 -4.9 acetylornithine transaminase compare
SMc02145 -3.2 -1.8 signal peptide protein compare
SMc03974 -3.1 -3.4 hypothetical protein compare
SMc00982 -3.1 -7.8 dioxygenase compare
SMc00641 -3.0 -4.2 D-3-phosphoglycerate dehydrogenase compare
SMa0789 -2.9 -4.1 GntR family transcriptional regulator compare
SMc01569 -2.8 -1.6 carbamoyl phosphate synthase small subunit compare
SMc02147 -2.8 -7.6 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc02833 -2.7 -3.2 penicillin-insensitive murein endopeptidase compare
SMc03981 -2.7 -5.9 phosphoglycerate kinase compare
SMc00881 -2.6 -10.3 2-dehydro-3-deoxygalactonokinase compare
SM_b20293 -2.5 -2.0 hypothetical protein compare
SMc00451 -2.3 -7.9 processing protease compare
SMc02141 -2.2 -4.4 phosphate transporter PhoU compare
SMc02753 -2.2 -2.3 PTS system transporter subunit IIA compare
SMc03229 -2.2 -1.4 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc04005 -2.1 -8.1 pyruvate kinase compare
SMc02140 -2.0 -2.1 phosphate regulon transcriptional regulatory protein compare
SMc02544 -2.0 -1.6 hypothetical protein compare
SMc04085 -1.9 -5.3 hypothetical protein compare
SMc01124 -1.8 -6.4 PII uridylyl-transferase compare
SMc02227 -1.8 -6.3 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc01430 -1.8 -3.0 acetolactate synthase 3 regulatory subunit compare
SMc02142 -1.7 -5.4 phosphate transporter ATP-binding protein compare
SMc03967 -1.7 -2.3 Holliday junction resolvase compare
SMc03070 -1.7 -8.6 glucose-6-phosphate 1-dehydrogenase compare
SMc01207 -1.6 -2.5 S-adenosylmethionine--tRNA ribosyltransferase-isomerase compare
SMc00492 -1.6 -1.1 hypothetical protein compare
SMc00321 -1.5 -6.0 tRNA pseudouridine synthase B compare
SMc02983 -1.5 -4.5 ornithine, DAP, or arginine decarboxylase compare
SMc00511 -1.5 -5.6 D-ribulose-5-phosphate 3-epimerase compare
SM_b20773 -1.5 -3.6 GntR family transcriptional regulator compare
SMc03949 -1.4 -2.5 nitrogen regulatory protein compare
SMc00427 -1.4 -2.4 peptide chain release factor RF-3 protein compare
SMc02172 -1.4 -6.2 transcriptional regulator compare
SMc01768 -1.3 -3.9 transcriptional regulator compare
SM_b21100 -1.3 -1.9 polysaccharide deacetylase compare
SMc03140 -1.3 -4.3 transcriptional regulator compare
SMc01501 -1.3 -2.3 mannitol 2-dehydrogenase compare
SMc02144 -1.3 -5.3 phosphate ABC transporter permease compare
SMc00286 -1.3 -2.2 hemolysin-type calcium-binding protein compare
SMc02102 -1.3 -3.3 hypothetical protein compare
SMc02234 -1.3 -2.6 hypothetical protein compare
SM_b21374 -1.3 -3.7 tagatose kinase (EC 2.7.1.101) (from data) compare
SMc00414 -1.3 -7.5 hypothetical protein compare
SMc01206 -1.3 -2.2 queuine tRNA-ribosyltransferase compare
SMc01164 -1.2 -5.8 hypothetical protein compare
SMc00088 -1.2 -1.6 hypothetical protein compare
SMc02574 -1.2 -1.8 imidazoleglycerol-phosphate dehydratase compare
SMc00981 -1.2 -4.9 ferredoxin protein compare
SMa2020 -1.1 -3.6 Transcriptional regulator compare
SMc03069 -1.1 -2.6 6-phosphogluconolactonase compare
SMc02143 -1.1 -3.0 phosphate ABC transporter permease compare
SMa0734 -1.1 -1.4 hypothetical protein compare
SM_b20258 -1.1 -2.9 transcriptional regulator compare
SMc01850 -1.1 -2.1 hypothetical protein compare
SMc02058 -1.1 -3.8 YAJC protein compare
SM_b20953 -1.1 -1.1 hypothetical protein compare
SMc00349 -1.0 -6.1 GTP-binding protein LepA compare
SM_b20148 -1.0 -4.3 transcriptional regulator compare
SMc01454 -1.0 -6.7 hypothetical protein compare
SMc04454 -1.0 -4.1 ABC transporter ATP-binding protein compare
SMa0093 -1.0 -2.7 Branched-chain amino acid aminotransferase compare
SMc02713 -1.0 -1.6 RNA polymerase sigma-E factor (sigma-24) protein compare
SMc00353 -1.0 -1.4 transmembrane protein compare
SM_b21691 -1.0 -6.8 nitrilotriacetate monooxygenase subunit A compare
SMc01578 -1.0 -5.7 aspartate aminotransferase compare
SMc02308 -1.0 -3.7 hypothetical protein compare
SMc02495 -1.0 -1.8 translaldolase compare
SMc01364 -0.9 -1.1 DNA topoisomerase I compare
SMc00802 -0.9 -1.0 hypothetical protein compare
SMc00450 -0.9 -2.4 protoheme IX farnesyltransferase compare
SMa0717 -0.9 -5.5 hypothetical protein compare
SMc02225 -0.9 -2.4 hypothetical protein compare
SMc00914 -0.9 -2.9 oxidoreductase compare
SMc02229 -0.9 -6.0 acyl-CoA dehydrogenase compare
SMa1442 -0.9 -3.2 GntR family transcriptional regulator compare
SM_b20573 -0.9 -5.6 NADH-dependent FMN reductase compare
SMc03258 -0.9 -4.2 transcriptional regulator compare
SMc04224 -0.9 -0.9 hypothetical protein compare
SM_b20290 -0.9 -1.9 transcriptional regulator compare
SMc01147 -0.9 -2.0 coproporphyrinogen III oxidase compare
SMc04432 -0.9 -2.3 hypothetical protein compare
SMc02362 -0.9 -2.4 cytochrome c-type biogenesis protein CcmE compare
SMc02838 -0.9 -4.0 phosphoglyceromutase compare
SM_b21102 -0.9 -4.4 transcriptional regulator compare
SMc00689 -0.9 -3.1 lipoprotein compare
SMc02373 -0.9 -1.2 hypothetical protein compare
SMc03242 -0.9 -2.5 GTP-binding protein compare
SMc04000 -0.8 -0.6 hypothetical protein compare
SMc02228 -0.8 -3.6 acetyl-CoA acetyltransferase compare
SM_b20282 -0.8 -2.3 spermidine/putrescine ABC transporter permease compare
SMa1058 -0.8 -1.8 hypothetical protein compare
SMc04348 -0.8 -0.7 transcriptional regulator compare
SMc02985 -0.8 -4.2 hypothetical protein compare
SMc02521 -0.8 -2.2 glycerol-3-phosphate regulon repressor transcription regulator protein compare
SMa0360 -0.8 -2.4 transposase compare
SMc01438 -0.8 -3.7 protease precursor signal peptide protein compare
SMc02714 -0.8 -1.1 hypothetical protein compare
SMc02112 -0.8 -2.8 hypothetical protein compare
SMc00963 -0.8 -2.4 hypothetical protein compare
SM_b21372 -0.8 -4.9 LacI family transcriptional regulator compare
SMc01368 -0.8 -2.7 transport transmembrane protein compare
SMc02620 -0.8 -4.3 hypothetical protein compare
SMc02787 -0.8 -1.9 hypothetical protein compare
SMc02615 -0.8 -1.9 signal peptide protein compare
SMc03993 -0.8 -3.5 hypothetical protein compare
SMa0955 -0.8 -1.4 GntR family transcriptional regulator compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source Lactulose in Sinorhizobium meliloti 1021

For carbon source Lactulose across organisms