Experiment set14IT028 for Sinorhizobium meliloti 1021

Compare to:

Beta-Lactose carbon source

200 most important genes:

  gene name fitness t score description  
SMc02572 -9.6 -6.6 imidazole glycerol phosphate synthase subunit HisH compare
SMc03797 -8.4 -5.8 homoserine O-succinyltransferase compare
SMc00236 -8.4 -5.8 Indole-3-glycerol phosphate synthase compare
SMc02766 -8.3 -9.9 tryptophan synthase subunit beta compare
SMc02123 -8.3 -3.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
SMc01843 -8.1 -5.6 5,10-methylenetetrahydrofolate reductase compare
SMc01494 -8.1 -7.9 phosphoserine phosphatase compare
SMc02899 -8.0 -7.8 prephenate dehydratase compare
SMc04405 -8.0 -5.5 3-isopropylmalate dehydrogenase compare
SMc00235 -8.0 -5.5 anthranilate phosphoribosyltransferase compare
SMc00640 -7.4 -7.3 phosphoserine aminotransferase compare
SMc04045 -7.4 -5.1 dihydroxy-acid dehydratase compare
SMc01726 -7.3 -5.0 acetylglutamate kinase compare
SMc00917 -7.3 -5.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
SMc00495 -7.3 -5.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
SMc02245 -7.2 -4.9 dihydroorotate dehydrogenase 2 compare
SMc00882 -7.1 -4.9 2-dehydro-3-deoxy-6-phosphogalactonate aldolase compare
SMc01431 -7.1 -4.9 acetolactate synthase 3 catalytic subunit compare
SMc00711 -7.1 -4.9 cyclohexadienyl dehydrogenase compare
SMc02767 -6.9 -9.4 N-(5'-phosphoribosyl)anthranilate isomerase compare
SMc02725 -6.9 -11.5 anthranilate synthase compare
SMc04026 -6.9 -9.4 glutamate synthase compare
SMc02717 -6.9 -9.4 2-isopropylmalate synthase compare
SMc00488 -6.8 -16.5 phosphoribosylformylglycinamidine synthase II compare
SMc03823 -6.7 -11.3 isopropylmalate isomerase large subunit compare
SMc00131 -6.7 -12.1 transcriptional regulator compare
SMc04028 -6.7 -14.9 glutamate synthase compare
SMc00092 -6.6 -12.0 phosphoadenosine phosphosulfate reductase compare
SMc00615 -6.6 -11.2 phosphoribosylaminoimidazole synthetase compare
SMc00493 -6.6 -4.5 phosphoribosylformylglycinamidine synthase I compare
SMc03895 -6.5 -16.4 pyruvate carboxylase compare
SMc02217 -6.4 -6.3 O-succinylhomoserine sulfhydrylase compare
SMa1635 -6.3 -2.6 hypothetical protein compare
SMc01054 -6.3 -5.6 required for sulfate utilization, putative electron source for sulfite reductase CysI (from data) compare
SMc00494 -6.2 -2.6 phosphoribosylformylglycinamidine synthase subunit PurS compare
SMc00614 -6.2 -7.4 phosphoribosylglycinamide formyltransferase compare
SM_b21655 -6.2 -16.0 Beta-galactosidase (EC 3.2.1.23) (from data) compare
SMc02765 -6.1 -11.6 tryptophan synthase subunit alpha compare
SMc02569 -6.1 -5.9 imidazole glycerol phosphate synthase subunit HisF compare
SMc00993 -6.0 -10.0 phosphoribosylamine--glycine ligase compare
SMc00918 -6.0 -10.2 ATP phosphoribosyltransferase regulatory subunit compare
SMc00554 -6.0 -5.8 amidophosphoribosyltransferase compare
SMc03112 -6.0 -17.2 B12-dependent methionine synthase compare
SMc02137 -5.9 -4.1 ornithine carbamoyltransferase compare
SMc00293 -5.8 -14.1 homoserine dehydrogenase compare
SMc02124 -5.7 -14.8 nitrite reductase compare
SMc00090 -5.7 -9.6 sulfate adenylyltransferase compare
SMc01801 -5.7 -3.9 N-acetylglutamylphosphate reductase (EC 1.2.1.38) (from data) compare
SMc00815 -5.6 -3.9 inosine 5'-monophosphate dehydrogenase compare
SM_b21174 -5.6 -6.6 phosphate uptake ABC transporter permease compare
SMc01004 -5.4 -7.7 phosphoribosyl-AMP cyclohydrolase compare
SMc03763 -5.4 -3.7 cytosine-specific methyltransferase compare
SMc03777 -5.3 -9.6 gamma-glutamyl phosphate reductase compare
SMc03979 -5.3 -3.7 glyceraldehyde-3-phosphate dehydrogenase compare
SMc00412 -5.3 -3.7 orotidine 5'-phosphate decarboxylase compare
SMc04088 -5.1 -8.3 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase compare
SMc02570 -5.0 -5.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
SMc00091 -4.9 -13.4 sulfate adenylyltransferase compare
SMc04001 -4.9 -2.0 phosphoribosylaminoimidazole carboxylase catalytic subunit protein compare
SMc02425 -4.8 -4.2 transcriptional regulator compare
SMc01360 -4.8 -4.7 aspartate carbamoyltransferase catalytic subunit compare
SMc02755 -4.8 -7.3 S-adenosyl-L-homocysteine hydrolase compare
SMc03229 -4.8 -3.3 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase compare
SMc01053 -4.6 -6.2 siroheme synthase compare
SMc01361 -4.6 -5.5 dihydroorotase compare
SMc02165 -4.5 -8.0 orotate phosphoribosyltransferase compare
SMc04002 -4.4 -6.9 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
SMc02307 -4.4 -9.8 histidinol dehydrogenase compare
SMc00294 -4.4 -11.2 aminotransferase compare
SMc02166 -4.3 -9.7 dihydroorotase compare
SMc01880 -4.2 -2.9 pantoate--beta-alanine ligase compare
SMc03776 -4.2 -5.0 gamma-glutamyl kinase compare
SMc03795 -4.1 -2.4 isopropylmalate isomerase small subunit compare
SMc02707 -4.1 -4.8 hypothetical protein compare
SMc03826 -4.1 -2.8 argininosuccinate synthase compare
SMc04346 -4.0 -5.1 ketol-acid reductoisomerase compare
SM_b21177 -3.9 -8.8 phosphate uptake ABC transporter ATP-binding protein compare
SMc00876 -3.9 -8.4 ATP-binding MRP protein compare
SMc02246 -3.9 -1.6 hypothetical protein compare
SM_b21175 -3.8 -6.3 phosphate uptake ABC transporter permease compare
SM_b20002 -3.8 -10.7 ABC transporter for Lactose, ATPase component (from data) conserved
SMc01770 -3.8 -1.6 serine hydroxymethyltransferase compare
SMc01881 -3.8 -4.7 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
SM_b21654 -3.7 -9.5 ABC transporter for Lactose, permease component 2 (from data) compare
SMc00017 -3.7 -2.0 homoserine kinase compare
SMc00641 -3.6 -5.5 D-3-phosphoglycerate dehydrogenase compare
SM_b21652 -3.6 -7.8 ABC transporter for Lactose, periplasmic substrate-binding component (from data) conserved
SMc03978 -3.6 -2.5 transketolase compare
SM_b21653 -3.6 -8.5 ABC transporter for Lactose, permease component 1 (from data) conserved
SM_b21176 -3.6 -5.4 phosphate uptake ABC transporter substrate-binding protein precursor compare
SMc00619 -3.6 -3.4 hypothetical protein compare
SMc02138 -3.4 -4.9 acetylornithine transaminase compare
SMc01215 -3.3 -2.2 carbamoyl phosphate synthase large subunit compare
SMc01569 -2.8 -1.6 carbamoyl phosphate synthase small subunit compare
SMc00982 -2.6 -7.3 dioxygenase compare
SMc00881 -2.6 -6.8 2-dehydro-3-deoxygalactonokinase compare
SMc02172 -2.5 -8.7 transcriptional regulator compare
SMc00334 -2.4 -2.6 cytidylate kinase compare
SMc02147 -2.4 -7.9 phosphate regulon sensor histidine kinase transmembrane protein compare
SMc00073 -2.3 -2.6 hypothetical protein compare
SMc02140 -2.3 -2.6 phosphate regulon transcriptional regulatory protein compare
SMc04005 -2.2 -9.3 pyruvate kinase compare
SMc01842 -2.2 -2.2 methyltransferase transcription regulator protein compare
SMc03974 -2.2 -4.1 hypothetical protein compare
SMc02435 -2.1 -3.7 methyltransferase compare
SMc00295 -2.0 -2.0 hypothetical protein compare
SMc01430 -2.0 -3.9 acetolactate synthase 3 regulatory subunit compare
SM_b21691 -2.0 -11.8 nitrilotriacetate monooxygenase subunit A compare
SMc02983 -1.9 -7.0 ornithine, DAP, or arginine decarboxylase compare
SMa0789 -1.9 -3.7 GntR family transcriptional regulator compare
SMc00451 -1.8 -8.0 processing protease compare
SMc04085 -1.8 -4.7 hypothetical protein compare
SMc00928 -1.8 -2.0 signal peptide protein compare
SMc01568 -1.8 -2.3 hypothetical protein compare
SMc01206 -1.8 -2.7 queuine tRNA-ribosyltransferase compare
SMc00414 -1.7 -9.3 hypothetical protein compare
SMc02574 -1.7 -2.8 imidazoleglycerol-phosphate dehydratase compare
SMc01364 -1.7 -1.6 DNA topoisomerase I compare
SMc00321 -1.6 -7.9 tRNA pseudouridine synthase B compare
SMc02234 -1.6 -2.3 hypothetical protein compare
SMc02142 -1.6 -4.8 phosphate transporter ATP-binding protein compare
SMc00013 -1.6 -2.4 cytochrome C oxidase subunit III transmembrane protein compare
SMc03981 -1.5 -5.0 phosphoglycerate kinase compare
SMc02141 -1.5 -3.0 phosphate transporter PhoU compare
SMc02144 -1.4 -4.6 phosphate ABC transporter permease compare
SMc01495 -1.4 -4.4 transcriptional regulator compare
SMc03140 -1.4 -4.5 transcriptional regulator compare
SMc02434 -1.4 -3.0 hypothetical protein compare
SMc02753 -1.4 -2.0 PTS system transporter subunit IIA compare
SMc01147 -1.4 -4.2 coproporphyrinogen III oxidase compare
SMc02143 -1.4 -3.2 phosphate ABC transporter permease compare
SMc01124 -1.4 -4.6 PII uridylyl-transferase compare
SMc03849 -1.3 -1.2 heme exporter C (cytochrome C-type biogenesis protein) transmembrane compare
SMc03070 -1.3 -5.6 glucose-6-phosphate 1-dehydrogenase compare
SMc04319 -1.3 -2.7 hypothetical protein compare
SM_b20573 -1.3 -7.2 NADH-dependent FMN reductase compare
SMc02582 -1.3 -3.9 hypothetical protein compare
SMc04348 -1.3 -1.4 transcriptional regulator compare
SMc01501 -1.3 -2.2 mannitol 2-dehydrogenase compare
SMc03949 -1.3 -3.5 nitrogen regulatory protein compare
SMc03100 -1.3 -0.7 hypothetical protein compare
SM_b21096 -1.3 -1.5 amino acid transporter ABC transporter ATP-binding protein compare
SMc02858 -1.2 -0.8 chaperone protein DnaJ compare
SMc03065 -1.2 -8.1 ABC transporter for D-maltose/D-trehalose/sucrose, ATPase component (AglK) (from data) compare
SMc00492 -1.2 -1.0 hypothetical protein compare
SMc00838 -1.2 -4.0 hypothetical protein compare
SM_b20293 -1.2 -1.4 hypothetical protein compare
SMc03061 -1.2 -7.6 ABC transporter for D-maltose/D-trehalose/sucrose, substrate-binding component (AglE) (from data) compare
SMc00689 -1.2 -3.9 lipoprotein compare
SMc03258 -1.2 -5.2 transcriptional regulator compare
SMc03063 -1.2 -8.8 ABC transporter for D-maltose/D-trehalose/sucrose, permease component 2 (AglG) (from data) compare
SMc03051 -1.1 -2.9 flagellar biosynthesis repressor FlbT compare
SMc02164 -1.1 -2.0 fructokinase compare
SMc01768 -1.1 -5.4 transcriptional regulator compare
SMc01441 -1.1 -4.0 membrane bound protease compare
SM_b20948 -1.1 -1.5 glucosyltransferase compare
SMc04296 -1.1 -1.0 cell division protein FtsZ compare
SMc02058 -1.1 -3.1 YAJC protein compare
SMc02833 -1.1 -1.5 penicillin-insensitive murein endopeptidase compare
SMc02115 -1.1 -1.2 hypothetical protein compare
SMc00239 -1.1 -1.1 hypothetical protein compare
SMc00914 -1.1 -3.0 oxidoreductase compare
SMa1765 -1.1 -1.4 hypothetical protein compare
SMa2020 -1.0 -5.3 Transcriptional regulator compare
SMc01578 -1.0 -6.5 aspartate aminotransferase compare
SMc00352 -1.0 -1.0 acetyltransferase compare
SMc03835 -1.0 -2.2 2'-5' RNA ligase compare
SMc03941 -1.0 -2.3 hypothetical protein compare
SMa1700 -1.0 -1.2 hypothetical protein compare
SMc01440 -1.0 -4.7 hydrolase serine protease transmembrane protein compare
SMc04000 -1.0 -0.7 hypothetical protein compare
SMc02051 -1.0 -2.4 hypothetical protein compare
SMc03120 -1.0 -2.1 ABC transporter ATP-binding protein compare
SMc02373 -1.0 -1.3 hypothetical protein compare
SMc03062 -1.0 -4.3 ABC transporter for D-maltose/D-trehalose/sucrose, permease component 1 (AglF) (from data) compare
SMc03993 -1.0 -4.2 hypothetical protein compare
SMc01368 -0.9 -3.4 transport transmembrane protein compare
SMc01028 -0.9 -6.4 phosphopyruvate hydratase compare
SMc01342 -0.9 -3.2 hypothetical protein compare
SMa0659 -0.9 -2.3 cytochrome c binding protein, carboxyl terminus compare
SMc03069 -0.9 -1.6 6-phosphogluconolactonase compare
SM_b21347 -0.9 -1.2 pectin degradation protein compare
SMc01015 -0.9 -1.9 hypothetical protein compare
SMc00427 -0.9 -1.8 peptide chain release factor RF-3 protein compare
SMa1201 -0.9 -1.6 hypothetical protein compare
SMc01164 -0.9 -5.3 hypothetical protein compare
SMc02510 -0.9 -0.8 ferric uptake regulation protein compare
SMc04327 -0.9 -1.0 hypothetical protein compare
SMc00511 -0.9 -2.7 D-ribulose-5-phosphate 3-epimerase compare
SM_b20773 -0.8 -2.2 GntR family transcriptional regulator compare
SMa0222 -0.8 -1.8 GntR family transcriptional regulator compare
SMc02521 -0.8 -3.0 glycerol-3-phosphate regulon repressor transcription regulator protein compare
SMa0905 -0.8 -1.3 hypothetical protein compare
SMc02227 -0.8 -3.9 fatty oxidation complex enoyl-COA hydratase/3-hydroxyacyl-COA dehydrogenase/3-hydroxybutyryl-COA epimerase compare
SMc02620 -0.8 -5.2 hypothetical protein compare
SMc02897 -0.8 -2.4 cytochrome C transmembrane protein compare
SM_b20657 -0.8 -3.1 hypothetical protein compare
SMa0543 -0.8 -1.5 hypothetical protein compare
SMc00404 -0.8 -0.9 hypothetical protein compare
SMc04024 -0.8 -4.1 membrane-bound lytic murein transglycosylase compare


Specific Phenotypes

For 9 genes in this experiment

For carbon source Beta-Lactose in Sinorhizobium meliloti 1021

For carbon source Beta-Lactose across organisms