Experiment set14IT028 for Bacteroides thetaiotaomicron VPI-5482

Compare to:

BHIS with DAMPA 60 uM

200 most detrimental genes:

  gene name fitness t score description  
BT2973 +2.9 6.6 transcriptional regulator (NCBI ptt file) compare
BT0892 +2.8 2.9 dihydroorotate dehydrogenase (NCBI ptt file) compare
BT2689 +2.6 11.2 conserved hypothetical protein (NCBI ptt file) compare
BT3928 +2.5 14.1 hypothetical protein (NCBI ptt file) compare
BT2417 +2.3 3.4 conserved hypothetical protein (NCBI ptt file) compare
BT0891 +2.1 3.5 dihydroorotate dehydrogenase electron transfer subunit (NCBI ptt file) compare
BT4753 +2.0 1.7 hypothetical protein (NCBI ptt file) compare
BT3843 +2.0 5.2 ATP-dependent Clp protease ATP-binding subunit (NCBI ptt file) compare
BT2027 +1.8 2.5 N-acetylmuramoyl-L-alanine amidase (NCBI ptt file) compare
BT1470 +1.8 2.8 putative two-component system sensor histidine kinase (NCBI ptt file) compare
BT3211 +1.8 4.3 conserved hypothetical protein (NCBI ptt file) compare
BT0723 +1.7 2.7 hypothetical protein (NCBI ptt file) compare
BT0776 +1.7 2.2 conserved hypothetical protein (NCBI ptt file) compare
BT1561 +1.7 1.5 hypothetical protein (NCBI ptt file) compare
BT3232 +1.7 2.4 gluconate 5-dehydrogenase (NCBI ptt file) compare
BT0692 +1.7 2.7 putative calcineurin superfamily phosphohydrolase (NCBI ptt file) compare
BT1854 +1.7 2.9 putative membrane-associated phospholipid phosphatase (NCBI ptt file) compare
BT2122 +1.7 3.0 lysyl-tRNA synthetase (NCBI ptt file) compare
BT0581 +1.6 2.9 putative acetyltransferase, GNAT family (NCBI ptt file) compare
BT3981 +1.5 2.1 hypothetical protein (NCBI ptt file) compare
BT3035 +1.5 9.6 carboxy-terminal processing protease precursor (NCBI ptt file) compare
BT1112 +1.5 2.1 transposase (NCBI ptt file) compare
BT2272 +1.4 4.9 conserved hypothetical protein (NCBI ptt file) compare
BT4649 +1.4 1.5 hypothetical protein (NCBI ptt file) compare
BT3253 +1.4 3.5 phosphoribosylamine--glycine ligase (NCBI ptt file) compare
BT4527 +1.4 4.8 hypothetical protein (NCBI ptt file) compare
BT1844 +1.4 6.0 transcriptional regulator, putative iron uptake regulation protein (NCBI ptt file) compare
BT4098 +1.3 1.8 Trk system K+ uptake protein trkA (NCBI ptt file) compare
BT4453 +1.3 1.7 6-pyruvoyl-tetrahydropterin synthase (NCBI ptt file) compare
BT4531 +1.3 5.4 conserved hypothetical protein (NCBI ptt file) compare
BT0418 +1.3 3.4 outer membrane porin F precursor (NCBI ptt file) compare
BT1222 +1.3 2.9 6-phosphogluconate dehydrogenase,decarboxylating (NCBI ptt file) compare
BT2059 +1.3 1.2 TonB (NCBI ptt file) compare
BT2142 +1.2 2.0 conserved hypothetical protein, with a conserved domain (NCBI ptt file) compare
BT3250 +1.2 5.4 conserved hypothetical protein (NCBI ptt file) compare
BT2749 +1.2 8.5 putative membrane-associated HD superfamily hydrolase (NCBI ptt file) compare
BT4530 +1.2 6.4 ATP-dependent DNA helicase recG (NCBI ptt file) compare
BT0582 +1.2 1.5 conserved hypothetical protein (NCBI ptt file) compare
BT4644 +1.2 2.9 putative anti-sigma factor (NCBI ptt file) compare
BT4698 +1.2 1.3 conserved hypothetical protein (NCBI ptt file) compare
BT1583 +1.2 1.7 putative protein disulfide isomerase (NCBI ptt file) compare
BT3072 +1.2 6.2 collagenase precursor (NCBI ptt file) compare
BT3770 +1.2 2.1 transcriptional regulator (NCBI ptt file) compare
BT4760 +1.2 2.8 hypothetical protein (NCBI ptt file) compare
BT0639 +1.2 1.4 conserved hypothetical protein (NCBI ptt file) compare
BT0753 +1.2 3.7 putative anti-sigma factor (NCBI ptt file) compare
BT0184 +1.2 2.9 uridine kinase (uridine monophosphokinase) (NCBI ptt file) compare
BT1457 +1.2 3.8 two-component system response regulator (NCBI ptt file) compare
BT4773 +1.2 2.2 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT0933 +1.2 4.4 hypothetical protein (NCBI ptt file) compare
BT1080 +1.2 2.1 hypothetical protein (NCBI ptt file) compare
BT1576 +1.2 1.6 conserved hypothetical protein, with a conserved domain (NCBI ptt file) compare
BT2684 +1.2 1.9 hypothetical protein (NCBI ptt file) compare
BT0833 +1.1 2.1 conserved hypothetical protein (NCBI ptt file) compare
BT3255 +1.1 4.9 putative N6-adenine-specific DNA methylase (NCBI ptt file) compare
BT0079 +1.1 2.2 putative anti-restriction protein (NCBI ptt file) compare
BT0699 +1.1 1.8 putative sugar transporter (NCBI ptt file) compare
BT2046 +1.1 1.2 putative cardiolipin synthetase (NCBI ptt file) compare
BT0067 +1.1 1.4 hypothetical protein (NCBI ptt file) compare
BT1380 +1.1 1.8 imidazole glycerol phosphate synthase subunit hisH (NCBI ptt file) compare
BT4161 +1.1 2.0 hypothetical protein (NCBI ptt file) compare
BT0239 +1.1 4.9 hypothetical protein (NCBI ptt file) compare
BT1868 +1.1 1.4 conserved hypothetical protein (NCBI ptt file) compare
BT1613 +1.1 5.0 conserved hypothetical protein (NCBI ptt file) compare
BT3251 +1.1 4.6 conserved hypothetical protein, putative integral membrane protein (NCBI ptt file) compare
BT4043 +1.1 5.7 dimethyladenosine transferase (NCBI ptt file) compare
BT1853 +1.1 0.8 putative sulfatase (NCBI ptt file) compare
BT0327 +1.1 2.3 glutamine ABC transporter, periplasmic glutamine-binding protein (glnH) (NCBI ptt file) compare
BT0044 +1.1 2.0 putative glycosyltransferase (NCBI ptt file) compare
BT0417 +1.1 2.1 hypothetical protein (NCBI ptt file) compare
BT1834 +1.1 4.5 putative hydrogenase (NCBI ptt file) compare
BT2453 +1.1 2.9 hypothetical protein (NCBI ptt file) compare
BT0618 +1.1 1.1 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfC (NCBI ptt file) compare
BT4455 +1.1 1.9 oxidoreductase, putative glycolate oxidase (NCBI ptt file) compare
BT0593 +1.1 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT2601 +1.0 2.8 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT0878 +1.0 0.8 ABC transporter, ATP-binding protein (NCBI ptt file) compare
BT1526 +1.0 2.5 myo-inositol-1-phosphate synthase (NCBI ptt file) compare
BT4533 +1.0 6.7 conserved hypothetical protein (NCBI ptt file) compare
BT3866 +1.0 7.5 ammonium-dependent carbamoyl phosphate synthetase CarB2 (EC 6.3.4.16) (from data) compare
BT1103 +1.0 2.0 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT1451 +1.0 1.7 hypothetical protein (NCBI ptt file) compare
BT0912 +1.0 1.4 DNA-binding protein HU (NCBI ptt file) compare
BT0900 +1.0 1.3 putative tetratricopeptide repeat family protein (NCBI ptt file) compare
BT0543 +1.0 2.5 glutamine synthetase (NCBI ptt file) compare
BT3392 +1.0 3.5 nitroreductase (NCBI ptt file) compare
BT2537 +1.0 2.7 hypothetical protein (NCBI ptt file) compare
BT4720 +1.0 2.8 putative RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT1212 +1.0 2.4 outer membrane efflux protein (NCBI ptt file) compare
BT1733 +1.0 4.1 putative phosphoribosylformylglycinamidine synthase (NCBI ptt file) compare
BT1356 +1.0 3.2 putative capsule polysaccharide export protein (NCBI ptt file) compare
BT1439 +1.0 4.0 Outer membrane binding protein for vancomycin (SusD-like) (from data) compare
BT1693 +1.0 2.3 periplasmic linker protein, putative multidrug resistance protein (NCBI ptt file) compare
BT0619 +1.0 1.1 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfD (NCBI ptt file) compare
BT0815 +1.0 1.8 conserved hypothetical protein (NCBI ptt file) compare
BT1278 +1.0 2.6 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT0159 +1.0 3.2 conserved hypothetical protein (NCBI ptt file) compare
BT4177 +1.0 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT4569 +1.0 1.6 hypothetical protein (NCBI ptt file) compare
BT4668 +0.9 1.9 arabinogalactan endo-1,4-beta-galactosidase (NCBI ptt file) compare
BT0772 +0.9 2.9 hypothetical protein (NCBI ptt file) compare
BT0927 +0.9 0.8 two-component system sensor histidine kinase (NCBI ptt file) compare
BT4382 +0.9 2.8 hypothetical protein (NCBI ptt file) compare
BT1410 +0.9 2.6 putative metallo-beta-lactamase (NCBI ptt file) compare
BT1107 +0.9 1.5 ferritin A (NCBI ptt file) compare
BT0231 +0.9 1.4 excisionase (NCBI ptt file) compare
BT0793 +0.9 1.8 xylose isomerase (NCBI ptt file) compare
BT4339 +0.9 1.3 glutamine synthetase (NCBI ptt file) compare
BT1881 +0.9 2.7 purine nucleoside phosphorylase I (NCBI ptt file) compare
BT0651 +0.9 1.7 thiamine biosynthesis protein ThiG (NCBI ptt file) compare
BT0173 +0.9 0.9 conserved hypothetical protein (NCBI ptt file) compare
BT4774 +0.9 1.4 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT1419 +0.9 1.4 hypothetical protein (NCBI ptt file) compare
BT3805 +0.9 2.7 two-component system sensor histidine kinase (NCBI ptt file) compare
BT0674 +0.9 2.0 carboxynorspermidine decarboxylase (NCBI ptt file) compare
BT3978 +0.9 4.2 putative cardiolipin synthetase (NCBI ptt file) compare
BT1142 +0.9 2.1 hypothetical protein (NCBI ptt file) compare
BT4024 +0.9 2.8 hypothetical protein (NCBI ptt file) compare
BT1148 +0.9 1.3 putative NADH dehydrogenase/NAD(P)H nitroreductase (NCBI ptt file) compare
BT1270 +0.9 1.8 putative Na+/H+ antiporter (NCBI ptt file) compare
BT4511 +0.9 1.3 hypothetical protein (NCBI ptt file) compare
BT0911 +0.9 4.7 putative integration host factor IHF alpha subunit (NCBI ptt file) compare
BT4618 +0.9 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT0156 +0.9 0.8 transcriptional regulator (NCBI ptt file) compare
BT4593 +0.9 2.4 conserved hypothetical protein (NCBI ptt file) compare
BT1256 +0.9 1.0 conserved hypothetical protein (NCBI ptt file) compare
BT0617 +0.9 0.8 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfB (NCBI ptt file) compare
BT1464 +0.9 1.7 putative acetyltransferase, (GNAT) family (NCBI ptt file) compare
BT1462 +0.9 2.2 hypothetical protein (NCBI ptt file) compare
BT2056 +0.9 3.2 conserved hypothetical protein (NCBI ptt file) compare
BT3802 +0.8 3.2 peptidyl-prolyl cis-trans isomerase, cyclophilin-type (NCBI ptt file) compare
BT1366 +0.8 2.3 hypothetical protein (NCBI ptt file) compare
BT0936 +0.8 1.2 hypothetical protein (NCBI ptt file) compare
BT1067 +0.8 3.3 hypothetical protein (NCBI ptt file) compare
BT1594 +0.8 2.4 putative ferredoxin (NCBI ptt file) compare
BT1608 +0.8 4.1 capsule biosynthesis protein capA (NCBI ptt file) compare
BT3757 +0.8 3.0 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) compare
BT2288 +0.8 2.9 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT1501 +0.8 1.4 major outer membrane protein OmpA (NCBI ptt file) compare
BT0178 +0.8 1.4 hypothetical protein (NCBI ptt file) compare
BT3268 +0.8 1.2 glucose-inhibited division protein A (NCBI ptt file) compare
BT3921 +0.8 3.2 hypothetical protein (NCBI ptt file) compare
BT2972 +0.8 1.4 conserved hypothetical protein (NCBI ptt file) compare
BT1220 +0.8 1.6 6-phosphogluconolactonase (NCBI ptt file) compare
BT0736 +0.8 1.6 putative transport protein (NCBI ptt file) compare
BT0656 +0.8 2.5 conserved hypothetical protein (NCBI ptt file) compare
BT2289 +0.8 3.0 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT0356 +0.8 1.9 aldose 1-epimerase precursor (NCBI ptt file) compare
BT3510 +0.8 2.8 hypothetical protein (NCBI ptt file) compare
BT0322 +0.8 1.8 putative oxidoreductase (NCBI ptt file) compare
BT2039 +0.8 2.8 cation efflux system protein, AcrB/AcrD/AcrF family protein (NCBI ptt file) compare
BT4693 +0.8 2.8 cation efflux system protein (NCBI ptt file) compare
BT0985 +0.8 1.9 putative sialic acid-specific acetylesterase II (NCBI ptt file) compare
BT1263 +0.8 0.8 putative protease I (NCBI ptt file) compare
BT1559 +0.8 3.2 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT2787 +0.8 6.4 GTP-binding elongation factor family protein TypA/BipA (NCBI ptt file) compare
BT0517 +0.8 2.9 flavodoxin (NCBI ptt file) compare
p5482_02 +0.8 3.4 hypothetical protein (NCBI) compare
BT0696 +0.8 2.0 putative membrane protein (NCBI ptt file) compare
BT3210 +0.8 1.6 cell division protein FtsX (NCBI ptt file) compare
BT1558 +0.8 2.3 hypothetical protein (NCBI ptt file) compare
BT0015 +0.8 1.4 rteB, two-component system response regulator (NCBI ptt file) compare
BT0512 +0.8 2.9 hypothetical protein (NCBI ptt file) compare
BT0778 +0.8 1.5 conserved hypothetical protein (NCBI ptt file) compare
BT0314 +0.8 2.0 ribosomal protein L11 methyltransferase (NCBI ptt file) compare
BT4300 +0.8 2.1 transcription regulator, CRP family (NCBI ptt file) compare
BT0501 +0.8 1.3 hypothetical protein (NCBI ptt file) compare
BT1316 +0.8 1.6 putative NADH dehydrogenase/NAD(P)H nitroreductase (NCBI ptt file) compare
BT0187 +0.8 1.3 conserved hypothetical protein (NCBI ptt file) compare
BT0621 +0.8 0.9 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfE (NCBI ptt file) compare
BT0170 +0.8 1.8 conserved hypothetical protein (NCBI ptt file) compare
BT3303 +0.8 5.4 ATP-dependent RNA helicase (NCBI ptt file) compare
BT4587 +0.8 1.6 conserved hypothetical protein (NCBI ptt file) compare
BT1021 +0.8 2.1 arabinosidase (NCBI ptt file) compare
BT2153 +0.8 1.3 putative Fe-S oxidoreductases (NCBI ptt file) compare
p5482_04 +0.8 5.2 hypothetical protein (NCBI) compare
BT3357 +0.8 5.0 ribonuclease III (NCBI ptt file) compare
BT2661 +0.8 3.1 hypothetical protein (NCBI ptt file) compare
BT1589 +0.8 1.4 hypothetical protein (NCBI ptt file) compare
BT0227 +0.8 1.7 hypothetical protein (NCBI ptt file) compare
BT2228 +0.8 3.9 hypothetical protein (NCBI ptt file) compare
BT4551 +0.8 0.9 putative GTPase, ThdF family (NCBI ptt file) compare
BT3803 +0.8 2.6 putative zinc protease (NCBI ptt file) compare
BT1976 +0.8 1.3 hypothetical protein (NCBI ptt file) compare
BT4249 +0.8 0.6 hypothetical protein (NCBI ptt file) compare
BT1367 +0.8 1.4 hydrolase, metal-dependent (NCBI ptt file) compare
BT1200 +0.8 2.0 hypothetical protein (NCBI ptt file) compare
BT3213 +0.8 1.4 tRNA pseudouridine synthase B (NCBI ptt file) compare
BT4370 +0.8 1.9 putative hemolysin (NCBI ptt file) compare
BT4529 +0.8 2.3 hypothetical protein (NCBI ptt file) compare
BT2103 +0.8 2.2 transcriptional regulator (NCBI ptt file) compare
BT1345 +0.8 2.3 glycosyltransferase (NCBI ptt file) compare
BT1221 +0.8 1.8 glucose-6-phosphate 1-dehydrogenase (NCBI ptt file) compare
BT4503 +0.8 1.0 conserved hypothetical protein (NCBI ptt file) compare
BT2845 +0.8 4.1 conserved hypothetical protein (NCBI ptt file) compare
BT0298 +0.8 1.3 cation efflux system protein (outer membrane protein) (NCBI ptt file) compare
BT3979 +0.7 1.8 putative methyltransferase (NCBI ptt file) compare
BT4421 +0.7 0.8 conserved hypothetical protein (NCBI ptt file) compare
BT4582 +0.7 3.5 amidophosphoribosyltransferase precursor (NCBI ptt file) compare
BT1843 +0.7 4.1 adenylosuccinate synthetase (NCBI ptt file) compare


Specific Phenotypes

For 4 genes in this experiment

For stress DAMPA in Bacteroides thetaiotaomicron VPI-5482

For stress DAMPA across organisms