Experiment set14IT019 for Klebsiella michiganensis M5al

Compare to:

Fungal_growth_media_mCAFEs_v1 with Thallium(I) acetate 0.05 mg/mL

200 most important genes:

  gene name fitness t score description  
BWI76_RS18930 -7.3 -4.7 histidinol-phosphate transaminase compare
BWI76_RS18935 -6.2 -9.2 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS04255 -5.9 -10.6 threonine synthase compare
BWI76_RS25700 -5.7 -6.7 heavy metal-responsive transcriptional regulator compare
BWI76_RS23365 -5.7 -3.0 LysR family transcriptional regulator compare
BWI76_RS20355 -5.6 -3.7 colicin V production protein compare
BWI76_RS18940 -5.5 -5.3 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS23220 -5.5 -7.9 amino-acid N-acetyltransferase compare
BWI76_RS18955 -5.3 -4.4 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS20895 -5.1 -3.5 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS02995 -5.0 -7.8 aspartate carbamoyltransferase compare
BWI76_RS20965 -5.0 -3.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS04250 -5.0 -6.9 homoserine kinase compare
BWI76_RS08385 -5.0 -2.3 citrate (Si)-synthase compare
BWI76_RS00440 -4.9 -1.4 CopG family transcriptional regulator compare
BWI76_RS04465 -4.9 -5.6 carbamoyl-phosphate synthase small subunit compare
BWI76_RS18950 -4.9 -4.3 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS20350 -4.8 -6.3 amidophosphoribosyltransferase compare
BWI76_RS01095 -4.8 -2.3 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS01115 -4.8 -2.2 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS05515 -4.8 -4.4 NADH:ubiquinone reductase (Na(+)-transporting) subunit F compare
BWI76_RS21265 -4.7 -13.6 phosphoribosylformylglycinamidine synthase compare
BWI76_RS01610 -4.7 -11.9 phosphoribosylamine--glycine ligase compare
BWI76_RS07065 -4.7 -6.3 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS26460 -4.7 -3.2 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS25115 -4.7 -6.7 argininosuccinate synthase compare
BWI76_RS11965 -4.6 -4.7 orotidine-5'-phosphate decarboxylase compare
BWI76_RS11840 -4.6 -4.9 tryptophan synthase subunit alpha compare
BWI76_RS26455 -4.6 -1.8 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS18925 -4.6 -6.0 histidinol dehydrogenase compare
BWI76_RS09910 -4.6 -16.2 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS20390 -4.5 -3.7 erythronate-4-phosphate dehydrogenase compare
BWI76_RS05260 -4.5 -1.3 chaperone compare
BWI76_RS27385 -4.5 -6.8 orotate phosphoribosyltransferase compare
BWI76_RS06525 -4.5 -4.3 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS22755 -4.5 -3.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS21465 -4.5 -5.8 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS18920 -4.4 -3.3 ATP phosphoribosyltransferase compare
BWI76_RS04685 -4.4 -11.0 putative leucine operon leader peptide compare
BWI76_RS00850 -4.4 -10.6 acetylglutamate kinase compare
BWI76_RS00855 -4.3 -9.6 argininosuccinate lyase compare
BWI76_RS07070 -4.2 -5.4 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS01615 -4.2 -9.7 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS04470 -4.2 -7.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS05490 -4.2 -4.2 Na(+)-translocating NADH-quinone reductase subunit A compare
BWI76_RS25280 -4.2 -1.2 RNase adaptor protein RapZ compare
BWI76_RS08520 -4.1 -2.0 colicin transporter TolQ compare
BWI76_RS00835 -4.1 -15.5 phosphoenolpyruvate carboxylase compare
BWI76_RS04305 -4.1 -1.1 molecular chaperone DnaJ compare
BWI76_RS08580 -4.1 -3.8 quinolinate synthetase compare
BWI76_RS11850 -4.1 -8.3 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS05500 -4.1 -9.0 NADH:ubiquinone reductase (Na(+)-transporting) subunit C compare
BWI76_RS00980 -4.1 -13.4 PLP-dependent threonine dehydratase compare
BWI76_RS00845 -4.0 -12.0 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS04665 -4.0 -17.9 3-isopropylmalate dehydratase small subunit compare
BWI76_RS01125 -4.0 -4.7 4-alpha-L-fucosyltransferase compare
BWI76_RS19495 -3.9 -1.1 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS27915 -3.9 -2.1 YceK/YidQ family lipoprotein compare
BWI76_RS24595 -3.9 -4.0 dihydroxyacetone kinase subunit DhaK compare
BWI76_RS01110 -3.9 -5.4 TDP-fucosamine acetyltransferase compare
BWI76_RS10990 -3.9 -2.5 dihydroorotase compare
BWI76_RS00975 -3.9 -11.2 dihydroxy-acid dehydratase compare
BWI76_RS11845 -3.9 -1.2 tryptophan synthase subunit beta compare
BWI76_RS21350 -3.8 -3.5 anti-RNA polymerase sigma factor SigE compare
BWI76_RS00990 -3.8 -10.1 ketol-acid reductoisomerase compare
BWI76_RS00875 -3.7 -5.0 DNA-binding transcriptional regulator FabR compare
BWI76_RS26000 -3.7 -7.6 aspartate aminotransferase family protein compare
BWI76_RS04675 -3.6 -5.5 3-isopropylmalate dehydrogenase compare
BWI76_RS11610 -3.6 -2.0 glutamate dehydrogenase compare
BWI76_RS05495 -3.6 -13.1 NADH:ubiquinone reductase (Na(+)-transporting) subunit B compare
BWI76_RS05015 -3.6 -2.0 transcriptional regulator compare
BWI76_RS21070 -3.6 -1.7 outer membrane protein assembly factor BamB compare
BWI76_RS04680 -3.6 -10.6 2-isopropylmalate synthase compare
BWI76_RS04245 -3.6 -11.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS27390 -3.5 -3.4 ribonuclease PH compare
BWI76_RS26425 -3.5 -5.7 zinc/cadmium/mercury/lead-transporting ATPase compare
BWI76_RS17915 -3.5 -6.4 membrane protein compare
BWI76_RS04670 -3.5 -10.2 3-isopropylmalate dehydratase large subunit compare
BWI76_RS19905 -3.5 -4.2 OmpK36 porin compare
BWI76_RS11860 -3.4 -8.1 anthranilate synthase component I compare
BWI76_RS19900 -3.4 -4.3 FAD:protein FMN transferase compare
BWI76_RS03010 -3.4 -5.9 ornithine carbamoyltransferase compare
BWI76_RS22765 -3.4 -9.9 sulfite reductase subunit alpha compare
BWI76_RS01655 -3.4 -8.4 homoserine O-succinyltransferase compare
BWI76_RS01275 -3.3 -7.3 LysR family transcriptional regulator compare
BWI76_RS05835 -3.3 -1.8 gamma-glutamyl-phosphate reductase compare
BWI76_RS22690 -3.2 -2.5 adenylyl-sulfate kinase compare
BWI76_RS23920 -3.1 -1.9 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS04845 -3.1 -8.5 nicotinate-nucleotide pyrophosphorylase compare
BWI76_RS24285 -3.1 -8.0 cystathionine beta-lyase compare
BWI76_RS04240 -3.1 -1.7 thr operon leader peptide compare
BWI76_RS26665 -3.1 -3.7 DNA-binding response regulator compare
BWI76_RS26670 -3.0 -7.9 two-component sensor histidine kinase compare
BWI76_RS07465 -3.0 -1.1 TetR family transcriptional regulator compare
BWI76_RS11855 -3.0 -7.3 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS09760 -2.9 -3.0 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS04160 -2.9 -3.0 phosphoserine phosphatase compare
BWI76_RS09335 -2.9 -1.1 baseplate assembly protein W compare
BWI76_RS09755 -2.9 -2.0 phosphoserine transaminase compare
BWI76_RS00805 -2.9 -5.0 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04705 -2.9 -4.4 DNA-binding transcriptional regulator FruR compare
BWI76_RS23265 -2.9 -1.9 hypothetical protein compare
BWI76_RS00785 -2.9 -5.0 cystathionine gamma-synthase compare
BWI76_RS06535 -2.8 -1.9 endopeptidase La compare
BWI76_RS04270 -2.8 -4.9 transaldolase compare
BWI76_RS16965 -2.8 -2.4 murein lipoprotein compare
BWI76_RS27450 -2.8 -6.9 ferredoxin--NADP(+) reductase compare
BWI76_RS25645 -2.8 -5.4 shikimate dehydrogenase compare
BWI76_RS08530 -2.8 -1.5 protein TolA compare
BWI76_RS24605 -2.8 -4.2 dihydroxyacetone kinase subunit DhaM compare
BWI76_RS19685 -2.8 -4.8 lysine transporter compare
BWI76_RS01220 -2.8 -5.7 DNA-dependent helicase II compare
BWI76_RS14320 -2.7 -2.1 hypothetical protein compare
BWI76_RS15825 -2.7 -1.0 hypothetical protein compare
BWI76_RS14300 -2.7 -2.7 hypothetical protein compare
BWI76_RS08210 -2.7 -1.0 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS08535 -2.7 -1.2 translocation protein TolB compare
BWI76_RS26620 -2.7 -0.7 Fe-S biogenesis protein NfuA compare
BWI76_RS20995 -2.7 -4.9 RNA degradosome polyphosphate kinase compare
BWI76_RS21580 -2.7 -1.2 SsrA-binding protein compare
BWI76_RS00940 -2.6 -6.7 transcriptional regulator HdfR compare
BWI76_RS25335 -2.6 -1.5 stringent starvation protein A compare
BWI76_RS01900 -2.6 -7.2 tRNA-dihydrouridine synthase A compare
BWI76_RS20380 -2.6 -0.7 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS21345 -2.6 -2.4 sigma-E factor regulatory protein RseB compare
BWI76_RS16425 -2.6 -2.2 hypothetical protein compare
BWI76_RS09645 -2.5 -0.7 thioredoxin-disulfide reductase compare
BWI76_RS10930 -2.5 -6.9 glucan biosynthesis protein G compare
BWI76_RS04645 -2.5 -2.9 3-dehydroquinase compare
BWI76_RS09615 -2.5 -2.2 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS01800 -2.5 -2.4 glucose-6-phosphate isomerase compare
BWI76_RS22760 -2.5 -6.9 sulfite reductase subunit beta compare
BWI76_RS24340 -2.4 -5.2 two-component sensor histidine kinase compare
BWI76_RS06530 -2.4 -5.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS21075 -2.4 -1.6 membrane protein compare
BWI76_RS21370 -2.4 -0.9 ATP-dependent RNA helicase SrmB compare
BWI76_RS23985 -2.3 -5.7 erythrose-4-phosphate dehydrogenase compare
BWI76_RS14410 -2.3 -2.8 hypothetical protein compare
BWI76_RS00240 -2.3 -1.3 FMN-binding protein MioC compare
BWI76_RS08525 -2.3 -1.8 colicin transporter compare
BWI76_RS06680 -2.3 -1.1 hypothetical protein compare
BWI76_RS24600 -2.3 -2.3 dihydroxyacetone kinase compare
BWI76_RS24580 -2.3 -3.4 PTS-dependent dihydroxyacetone kinase operon transcriptional regulator DhaR compare
BWI76_RS09640 -2.3 -2.1 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS22120 -2.2 -4.7 glutamate--cysteine ligase compare
BWI76_RS09970 -2.2 -0.8 porin OmpA compare
BWI76_RS12090 -2.2 -2.3 HNH endonuclease compare
BWI76_RS20640 -2.2 -4.2 cysteine synthase A compare
BWI76_RS01280 -2.2 -12.1 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase compare
BWI76_RS06675 -2.1 -6.6 nickel/cobalt efflux protein RcnA compare
BWI76_RS21360 -2.1 -4.8 L-aspartate oxidase compare
BWI76_RS17910 -2.1 -4.6 hypothetical protein compare
BWI76_RS22695 -2.1 -3.7 sulfate adenylyltransferase compare
BWI76_RS24075 -2.1 -3.3 glutathione synthase compare
BWI76_RS00960 -2.1 -4.7 acetolactate synthase 2 catalytic subunit compare
BWI76_RS24850 -2.1 -6.3 DeoR family transcriptional regulator compare
BWI76_RS21450 -2.1 -1.8 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS26055 -2.1 -7.4 siroheme synthase compare
BWI76_RS00600 -2.1 -5.1 LacI family transcriptional regulator compare
BWI76_RS05510 -2.1 -3.3 NADH:ubiquinone reductase (Na(+)-transporting) subunit E compare
BWI76_RS05840 -2.0 -3.0 glutamate 5-kinase compare
BWI76_RS22805 -2.0 -6.0 GTP diphosphokinase compare
BWI76_RS19840 -2.0 -0.5 hypothetical protein compare
BWI76_RS02530 -2.0 -1.2 tRNA dimethylallyltransferase compare
BWI76_RS21475 -2.0 -2.5 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS25000 -2.0 -1.2 malonate decarboxylase acyl carrier protein compare
BWI76_RS15965 -2.0 -2.9 MFS transporter compare
BWI76_RS23360 -2.0 -1.0 diaminopimelate decarboxylase compare
BWI76_RS23330 -2.0 -3.5 transcriptional regulator GalR compare
BWI76_RS01550 -1.9 -4.8 thiamine phosphate synthase compare
BWI76_RS00970 -1.9 -2.6 branched chain amino acid aminotransferase compare
BWI76_RS16980 -1.9 -3.6 bifunctional cysteine desulfurase/selenocysteine lyase compare
BWI76_RS15760 -1.9 -1.6 hypothetical protein compare
BWI76_RS09730 -1.9 -0.7 pyruvate formate lyase 1-activating protein compare
BWI76_RS09190 -1.9 -1.3 hypothetical protein compare
BWI76_RS10475 -1.9 -3.4 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS06485 -1.9 -1.8 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS25480 -1.9 -5.5 ribonuclease E/G compare
BWI76_RS00180 -1.9 -0.7 F0F1 ATP synthase subunit epsilon compare
BWI76_RS06495 -1.9 -6.5 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS24885 -1.8 -0.8 PTS galactitol transporter subunit IIB compare
BWI76_RS04990 -1.8 -3.4 pantoate--beta-alanine ligase compare
BWI76_RS14005 -1.8 -1.3 TetR family transcriptional regulator compare
BWI76_RS04100 -1.8 -2.7 peptide chain release factor 3 compare
BWI76_RS20740 -1.8 -4.2 coproporphyrinogen III oxidase compare
BWI76_RS01080 -1.8 -4.4 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase compare
BWI76_RS26470 -1.7 -4.1 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS18000 -1.7 -3.5 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF compare
BWI76_RS08500 -1.7 -2.0 cytochrome d ubiquinol oxidase subunit 2 compare
BWI76_RS26390 -1.7 -4.9 cell division protein FtsX compare
BWI76_RS26440 -1.7 -1.0 hypothetical protein compare
BWI76_RS00965 -1.7 -0.6 acetolactate synthase 2 small subunit compare
BWI76_RS08495 -1.7 -2.6 cytochrome bd-I ubiquinol oxidase subunit I compare
BWI76_RS02550 -1.7 -3.6 protease modulator HflC compare
BWI76_RS01385 -1.7 -1.9 potassium transporter compare
BWI76_RS19770 -1.7 -1.4 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS22700 -1.7 -3.7 sulfate adenylyltransferase subunit 2 compare
BWI76_RS01135 -1.7 -4.5 lipopolysaccharide N-acetylmannosaminouronosyltransferase compare
BWI76_RS17300 -1.7 -0.8 tRNA-Tyr compare
BWI76_RS20900 -1.7 -0.9 outer membrane protein assembly factor BamC compare


Specific Phenotypes

For 13 genes in this experiment

For stress Thallium(I) acetate in Klebsiella michiganensis M5al

For stress Thallium(I) acetate across organisms