Experiment set14IT013 for Klebsiella michiganensis M5al

Compare to:

Fungal_growth_media_mCAFEs_v1 with Zinc sulfate heptahydrate 2 mM

200 most important genes:

  gene name fitness t score description  
BWI76_RS20355 -6.6 -2.5 colicin V production protein compare
BWI76_RS08580 -6.5 -3.2 quinolinate synthetase compare
BWI76_RS20350 -5.7 -5.9 amidophosphoribosyltransferase compare
BWI76_RS17860 -5.5 -1.2 YoaH family protein compare
BWI76_RS18955 -5.5 -4.2 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS01615 -5.2 -8.7 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS04255 -5.2 -10.8 threonine synthase compare
BWI76_RS20965 -5.1 -3.3 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS26425 -5.1 -7.6 zinc/cadmium/mercury/lead-transporting ATPase compare
BWI76_RS11850 -5.1 -10.0 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS08385 -4.9 -1.8 citrate (Si)-synthase compare
BWI76_RS11965 -4.9 -3.6 orotidine-5'-phosphate decarboxylase compare
BWI76_RS25700 -4.8 -5.3 heavy metal-responsive transcriptional regulator compare
BWI76_RS01610 -4.8 -9.0 phosphoribosylamine--glycine ligase compare
BWI76_RS21265 -4.7 -13.1 phosphoribosylformylglycinamidine synthase compare
BWI76_RS26455 -4.7 -1.4 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS01170 -4.7 -3.3 uroporphyrinogen-III C-methyltransferase compare
BWI76_RS27390 -4.7 -5.5 ribonuclease PH compare
BWI76_RS21350 -4.7 -3.8 anti-RNA polymerase sigma factor SigE compare
BWI76_RS05260 -4.6 -1.0 chaperone compare
BWI76_RS17400 -4.6 -1.0 transporter compare
BWI76_RS26665 -4.5 -2.2 DNA-binding response regulator compare
BWI76_RS12090 -4.5 -1.6 HNH endonuclease compare
BWI76_RS18940 -4.4 -5.2 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS07070 -4.4 -3.6 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS04675 -4.4 -5.8 3-isopropylmalate dehydrogenase compare
BWI76_RS00835 -4.4 -11.3 phosphoenolpyruvate carboxylase compare
BWI76_RS18925 -4.3 -5.0 histidinol dehydrogenase compare
BWI76_RS22760 -4.3 -6.5 sulfite reductase subunit beta compare
BWI76_RS18930 -4.3 -4.1 histidinol-phosphate transaminase compare
BWI76_RS06680 -4.3 -0.9 hypothetical protein compare
BWI76_RS04470 -4.2 -9.0 carbamoyl phosphate synthase large subunit compare
BWI76_RS23265 -4.2 -1.3 hypothetical protein compare
BWI76_RS09335 -4.2 -0.9 baseplate assembly protein W compare
BWI76_RS09910 -4.2 -18.3 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS11855 -4.2 -6.0 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS08605 -4.1 -1.5 phosphoglyceromutase compare
BWI76_RS08520 -4.1 -1.5 colicin transporter TolQ compare
BWI76_RS23220 -4.1 -7.2 amino-acid N-acetyltransferase compare
BWI76_RS00755 -4.0 -3.2 ATP-dependent protease subunit HslV compare
BWI76_RS26460 -4.0 -3.1 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS10990 -4.0 -2.0 dihydroorotase compare
BWI76_RS09625 -4.0 -0.9 hypothetical protein compare
BWI76_RS05840 -4.0 -2.2 glutamate 5-kinase compare
BWI76_RS22690 -3.9 -1.9 adenylyl-sulfate kinase compare
BWI76_RS00975 -3.9 -11.0 dihydroxy-acid dehydratase compare
BWI76_RS23365 -3.8 -3.4 LysR family transcriptional regulator compare
BWI76_RS00845 -3.8 -9.7 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS22755 -3.8 -3.6 phosphoadenosine phosphosulfate reductase compare
BWI76_RS25645 -3.8 -5.8 shikimate dehydrogenase compare
BWI76_RS04845 -3.8 -5.6 nicotinate-nucleotide pyrophosphorylase compare
BWI76_RS25300 -3.8 -2.0 hybrid sensor histidine kinase/response regulator compare
BWI76_RS04525 -3.8 -1.4 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS08275 -3.8 -1.1 LexA regulated protein compare
BWI76_RS21450 -3.7 -1.6 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS13755 -3.7 -1.1 hypothetical protein compare
BWI76_RS22765 -3.7 -8.6 sulfite reductase subunit alpha compare
BWI76_RS00785 -3.7 -6.4 cystathionine gamma-synthase compare
BWI76_RS04665 -3.7 -17.3 3-isopropylmalate dehydratase small subunit compare
BWI76_RS11300 -3.6 -0.8 cupin compare
BWI76_RS04250 -3.6 -5.7 homoserine kinase compare
BWI76_RS21070 -3.6 -1.3 outer membrane protein assembly factor BamB compare
BWI76_RS04240 -3.6 -0.9 thr operon leader peptide compare
BWI76_RS24285 -3.6 -8.3 cystathionine beta-lyase compare
BWI76_RS05015 -3.6 -1.5 transcriptional regulator compare
BWI76_RS21360 -3.6 -5.3 L-aspartate oxidase compare
BWI76_RS00855 -3.6 -8.7 argininosuccinate lyase compare
BWI76_RS22700 -3.6 -3.2 sulfate adenylyltransferase subunit 2 compare
BWI76_RS00980 -3.5 -9.5 PLP-dependent threonine dehydratase compare
BWI76_RS19770 -3.5 -1.1 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS08530 -3.5 -1.1 protein TolA compare
BWI76_RS18935 -3.5 -7.4 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS21465 -3.5 -2.7 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04245 -3.4 -11.3 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS11980 -3.4 -1.0 DeoR family transcriptional regulator compare
BWI76_RS15215 -3.4 -0.7 N-acetyltransferase compare
BWI76_RS05075 -3.4 -0.7 type II secretion system protein GspG compare
BWI76_RS11845 -3.3 -1.7 tryptophan synthase subunit beta compare
BWI76_RS17975 -3.3 -3.3 tail-specific protease compare
BWI76_RS10745 -3.3 -0.7 hypothetical protein compare
BWI76_RS18470 -3.3 -2.8 hypothetical protein compare
BWI76_RS08750 -3.3 -1.2 kinase inhibitor compare
BWI76_RS18950 -3.3 -4.5 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS26000 -3.3 -6.4 aspartate aminotransferase family protein compare
BWI76_RS21475 -3.3 -2.9 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS26440 -3.3 -1.0 hypothetical protein compare
BWI76_RS05835 -3.2 -1.4 gamma-glutamyl-phosphate reductase compare
BWI76_RS06405 -3.2 -1.7 2-dehydropantoate 2-reductase compare
BWI76_RS11860 -3.2 -8.7 anthranilate synthase component I compare
BWI76_RS14005 -3.2 -1.2 TetR family transcriptional regulator compare
BWI76_RS20740 -3.2 -4.1 coproporphyrinogen III oxidase compare
BWI76_RS07065 -3.2 -5.4 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS00850 -3.2 -6.4 acetylglutamate kinase compare
BWI76_RS01655 -3.2 -8.9 homoserine O-succinyltransferase compare
BWI76_RS27385 -3.2 -5.8 orotate phosphoribosyltransferase compare
BWI76_RS26730 -3.1 -5.6 inner membrane protein YhjD compare
BWI76_RS00990 -3.1 -10.9 ketol-acid reductoisomerase compare
BWI76_RS16965 -3.1 -1.8 murein lipoprotein compare
BWI76_RS14320 -3.1 -1.5 hypothetical protein compare
BWI76_RS04160 -3.1 -2.8 phosphoserine phosphatase compare
BWI76_RS24740 -3.1 -2.6 GntR family transcriptional regulator compare
BWI76_RS15965 -3.0 -3.8 MFS transporter compare
BWI76_RS00965 -3.0 -0.6 acetolactate synthase 2 small subunit compare
BWI76_RS18920 -3.0 -2.4 ATP phosphoribosyltransferase compare
BWI76_RS01110 -3.0 -5.2 TDP-fucosamine acetyltransferase compare
BWI76_RS20895 -3.0 -4.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS08525 -3.0 -1.1 colicin transporter compare
BWI76_RS09655 -3.0 -4.0 leucine-responsive regulatory protein compare
BWI76_RS07465 -3.0 -0.9 TetR family transcriptional regulator compare
BWI76_RS00720 -3.0 -1.2 DNA-binding response regulator compare
BWI76_RS02995 -3.0 -5.6 aspartate carbamoyltransferase compare
BWI76_RS16315 -2.9 -0.9 SirA-like protein compare
BWI76_RS09755 -2.9 -1.8 phosphoserine transaminase compare
BWI76_RS04670 -2.9 -8.6 3-isopropylmalate dehydratase large subunit compare
BWI76_RS19010 -2.9 -1.6 polysaccharide pyruvyl transferase yvff compare
BWI76_RS09760 -2.8 -2.6 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS25115 -2.8 -3.9 argininosuccinate synthase compare
BWI76_RS06535 -2.8 -1.7 endopeptidase La compare
BWI76_RS01800 -2.8 -1.5 glucose-6-phosphate isomerase compare
BWI76_RS19845 -2.8 -5.5 phosphatase compare
BWI76_RS04990 -2.8 -4.1 pantoate--beta-alanine ligase compare
BWI76_RS22805 -2.8 -8.0 GTP diphosphokinase compare
BWI76_RS11840 -2.7 -4.2 tryptophan synthase subunit alpha compare
BWI76_RS16200 -2.7 -1.1 NAD(P) transhydrogenase subunit beta compare
BWI76_RS22695 -2.7 -3.5 sulfate adenylyltransferase compare
BWI76_RS26620 -2.7 -0.6 Fe-S biogenesis protein NfuA compare
BWI76_RS04685 -2.7 -7.8 putative leucine operon leader peptide compare
BWI76_RS01080 -2.7 -6.0 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase compare
BWI76_RS04465 -2.7 -3.8 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04995 -2.7 -5.6 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
BWI76_RS24600 -2.7 -1.9 dihydroxyacetone kinase compare
BWI76_RS08210 -2.7 -0.8 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS14915 -2.7 -3.0 hypothetical protein compare
BWI76_RS12860 -2.6 -1.5 hypothetical protein compare
BWI76_RS09640 -2.6 -1.4 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS08535 -2.6 -0.9 translocation protein TolB compare
BWI76_RS09645 -2.6 -0.5 thioredoxin-disulfide reductase compare
BWI76_RS04680 -2.6 -12.6 2-isopropylmalate synthase compare
BWI76_RS02815 -2.6 -1.3 fructose-bisphosphatase class I compare
BWI76_RS21165 -2.6 -1.1 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS11610 -2.6 -1.6 glutamate dehydrogenase compare
BWI76_RS04645 -2.6 -3.0 3-dehydroquinase compare
BWI76_RS10835 -2.6 -0.9 hypothetical protein compare
BWI76_RS08495 -2.6 -3.4 cytochrome bd-I ubiquinol oxidase subunit I compare
BWI76_RS12070 -2.6 -0.8 hypothetical protein compare
BWI76_RS17915 -2.5 -5.2 membrane protein compare
BWI76_RS01125 -2.5 -3.2 4-alpha-L-fucosyltransferase compare
BWI76_RS20390 -2.5 -3.3 erythronate-4-phosphate dehydrogenase compare
BWI76_RS01550 -2.5 -5.3 thiamine phosphate synthase compare
BWI76_RS26055 -2.5 -5.3 siroheme synthase compare
BWI76_RS20640 -2.5 -2.7 cysteine synthase A compare
BWI76_RS21370 -2.5 -0.7 ATP-dependent RNA helicase SrmB compare
BWI76_RS15960 -2.4 -3.0 LysR family transcriptional regulator compare
BWI76_RS14770 -2.4 -0.9 PTS IIA 2 domain protein compare
BWI76_RS23985 -2.4 -4.5 erythrose-4-phosphate dehydrogenase compare
BWI76_RS04985 -2.4 -3.3 aspartate 1-decarboxylase compare
BWI76_RS08020 -2.4 -5.0 serine-type D-Ala-D-Ala carboxypeptidase compare
BWI76_RS25335 -2.3 -1.2 stringent starvation protein A compare
BWI76_RS24605 -2.3 -5.1 dihydroxyacetone kinase subunit DhaM compare
BWI76_RS17770 -2.3 -1.2 isomerase/hydrolase compare
BWI76_RS21235 -2.3 -0.7 hypothetical protein compare
BWI76_RS17190 -2.3 -1.1 TonB system transport protein TonB compare
BWI76_RS01095 -2.3 -1.5 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS00240 -2.3 -1.0 FMN-binding protein MioC compare
BWI76_RS09970 -2.3 -0.6 porin OmpA compare
BWI76_RS25060 -2.3 -4.5 lipoprotein NlpI compare
BWI76_RS03010 -2.3 -4.9 ornithine carbamoyltransferase compare
BWI76_RS00960 -2.2 -3.5 acetolactate synthase 2 catalytic subunit compare
BWI76_RS24850 -2.2 -3.7 DeoR family transcriptional regulator compare
BWI76_RS20880 -2.2 -1.7 esterase compare
BWI76_RS02550 -2.2 -4.6 protease modulator HflC compare
BWI76_RS15760 -2.2 -1.4 hypothetical protein compare
BWI76_RS27915 -2.2 -1.2 YceK/YidQ family lipoprotein compare
BWI76_RS02735 -2.2 -1.9 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS17980 -2.2 -3.1 RNA chaperone ProQ compare
BWI76_RS25705 -2.2 -3.0 hypothetical protein compare
BWI76_RS27820 -2.1 -0.6 ilvB operon leader peptide IvbL compare
BWI76_RS18000 -2.1 -4.3 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF compare
BWI76_RS01090 -2.1 -4.6 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
BWI76_RS25425 -2.1 -0.6 arginine repressor compare
BWI76_RS10930 -2.1 -5.1 glucan biosynthesis protein G compare
BWI76_RS00875 -2.1 -3.0 DNA-binding transcriptional regulator FabR compare
BWI76_RS01275 -2.1 -7.0 LysR family transcriptional regulator compare
BWI76_RS24580 -2.1 -3.6 PTS-dependent dihydroxyacetone kinase operon transcriptional regulator DhaR compare
BWI76_RS00805 -2.1 -4.5 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS14305 -2.1 -3.7 metallophosphoesterase compare
BWI76_RS19840 -2.1 -0.4 hypothetical protein compare
BWI76_RS12750 -2.1 -2.9 hypothetical protein compare
BWI76_RS26670 -2.1 -6.1 two-component sensor histidine kinase compare
BWI76_RS00985 -2.1 -5.2 transcriptional regulator IlvY compare
BWI76_RS25315 -2.1 -7.2 glutamate synthase large subunit compare
BWI76_RS21345 -2.1 -1.7 sigma-E factor regulatory protein RseB compare
BWI76_RS23885 -2.0 -0.6 2-octaprenylphenol hydroxylase compare
BWI76_RS24280 -2.0 -3.4 biopolymer transporter ExbB compare
BWI76_RS05005 -2.0 -1.7 polynucleotide adenylyltransferase compare
BWI76_RS23360 -2.0 -0.8 diaminopimelate decarboxylase compare
BWI76_RS24100 -2.0 -2.3 YggS family pyridoxal phosphate enzyme compare
BWI76_RS02530 -2.0 -0.9 tRNA dimethylallyltransferase compare
BWI76_RS00345 -2.0 -3.0 protein disulfide oxidoreductase DsbA compare
BWI76_RS25160 -2.0 -1.9 transcription elongation factor GreA compare


Specific Phenotypes

For 3 genes in this experiment

For stress Zinc sulfate heptahydrate in Klebsiella michiganensis M5al

For stress Zinc sulfate heptahydrate across organisms