Experiment set14IT002 for Bacteroides thetaiotaomicron VPI-5482

Compare to:

BHIS with Simvastatin 30 uM

200 most detrimental genes:

  gene name fitness t score description  
BT2973 +5.9 8.8 transcriptional regulator (NCBI ptt file) compare
BT2142 +4.3 5.5 conserved hypothetical protein, with a conserved domain (NCBI ptt file) compare
BT3978 +4.2 17.5 putative cardiolipin synthetase (NCBI ptt file) compare
BT2689 +4.0 6.0 conserved hypothetical protein (NCBI ptt file) compare
BT1684 +2.8 8.6 conserved hypothetical protein (NCBI ptt file) compare
BT3035 +2.8 13.9 carboxy-terminal processing protease precursor (NCBI ptt file) compare
BT1804 +2.7 8.4 electron transfer flavoprotein beta-subunit (NCBI ptt file) compare
BT1806 +2.7 13.0 acyl-CoA dehydrogenase (NCBI ptt file) compare
BT2749 +2.5 13.3 putative membrane-associated HD superfamily hydrolase (NCBI ptt file) compare
BT4028 +2.3 2.2 hypothetical protein (NCBI ptt file) compare
BT3920 +2.3 3.0 conserved hypothetical protein (NCBI ptt file) compare
BT2972 +2.3 2.2 conserved hypothetical protein (NCBI ptt file) compare
BT0596 +2.3 2.4 putative transcriptional regulator (NCBI ptt file) compare
BT3843 +2.2 4.1 ATP-dependent Clp protease ATP-binding subunit (NCBI ptt file) compare
BT1350 +2.2 8.0 CDP-glucose 4,6-dehydratase (NCBI ptt file) compare
BT1356 +2.2 6.6 putative capsule polysaccharide export protein (NCBI ptt file) compare
BT1358 +2.2 5.0 putative transcriptional regulator (NCBI ptt file) compare
BT4208 +2.1 5.4 phosphohydrolase (NCBI ptt file) compare
BT1805 +2.1 5.7 electron transfer flavoprotein alpha-subunit (NCBI ptt file) compare
BT1352 +2.1 5.4 putative glycosyltransferase HI1698 (NCBI ptt file) compare
BT3839 +2.0 2.0 ABC transporter ATP-binding protein (NCBI ptt file) compare
BT1195 +1.9 4.1 monofunctional biosynthetic peptidoglycan transglycosylase (NCBI ptt file) compare
BT0593 +1.9 2.1 conserved hypothetical protein (NCBI ptt file) compare
BT1346 +1.9 7.4 capsule biosynthesis protein capA (NCBI ptt file) compare
BT0067 +1.9 1.7 hypothetical protein (NCBI ptt file) compare
BT2040 +1.8 5.6 hypothetical protein (NCBI ptt file) compare
BT1342 +1.7 6.8 putative UDP-glucuronic acid epimerase (NCBI ptt file) compare
BT3255 +1.7 5.9 putative N6-adenine-specific DNA methylase (NCBI ptt file) compare
BT1137 +1.7 1.9 hypothetical protein (NCBI ptt file) compare
BT1071 +1.7 3.1 hypothetical protein (NCBI ptt file) compare
BT1340 +1.7 6.3 putative lipopolysaccharide biosynthesis glycosyltransferase (NCBI ptt file) compare
BT1353 +1.7 4.0 glycosyltransferase (NCBI ptt file) compare
BT3251 +1.7 5.5 conserved hypothetical protein, putative integral membrane protein (NCBI ptt file) compare
BT1354 +1.7 6.1 putative flippase (NCBI ptt file) compare
BT1126 +1.7 2.8 mobilization protein BmgA (NCBI ptt file) compare
BT3414 +1.7 8.3 Mg2+/Co2+ transporter (NCBI ptt file) compare
BT0443 +1.7 2.4 thermostable beta-glucosidase B (NCBI ptt file) compare
BT4017 +1.7 2.9 hypothetical protein (NCBI ptt file) compare
BT0753 +1.7 3.8 putative anti-sigma factor (NCBI ptt file) compare
BT1343 +1.7 5.8 putative capsule biosynthesis protein (NCBI ptt file) compare
BT3979 +1.7 3.4 putative methyltransferase (NCBI ptt file) compare
BT2036 +1.7 4.5 conserved hypothetical protein (NCBI ptt file) compare
BT1536 +1.6 4.8 ABC transporter permease (NCBI ptt file) compare
BT1351 +1.6 5.3 glucose-1-phosphate cytidylyltransferase (NCBI ptt file) compare
BT0704 +1.6 1.2 phosphoribosylglycinamide formyltransferase 2 (NCBI ptt file) compare
BT2931 +1.6 4.8 hypothetical protein (NCBI ptt file) compare
BT2546 +1.6 5.9 transcriptional regulator (NCBI ptt file) compare
BT4720 +1.6 3.9 putative RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT1355 +1.6 3.1 hypothetical protein (NCBI ptt file) compare
BT4753 +1.6 0.9 hypothetical protein (NCBI ptt file) compare
BT0616 +1.6 2.1 conserved hypothetical protein (NCBI ptt file) compare
BT2417 +1.6 1.4 conserved hypothetical protein (NCBI ptt file) compare
BT0013 +1.5 2.0 hypothetical protein (NCBI ptt file) compare
BT4239 +1.5 5.7 hypothetical protein (NCBI ptt file) compare
BT1345 +1.5 4.8 glycosyltransferase (NCBI ptt file) compare
BT2756 +1.5 6.8 anaerobic C4-dicarboxylate transporter dcuB (NCBI ptt file) compare
BT1612 +1.5 3.2 hypothetical protein (NCBI ptt file) compare
BT3368 +1.5 1.4 putative glycosyltransferase (NCBI ptt file) compare
BT0115 +1.4 3.0 arsenate reductase (NCBI ptt file) compare
BT1344 +1.4 5.1 putative glycosyltransferase (NCBI ptt file) compare
BT1339 +1.4 4.6 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase (NCBI ptt file) compare
BT1296 +1.4 5.2 V-type ATP synthase subunit I (NCBI ptt file) compare
BT2781 +1.4 3.1 putative mannose-1-phosphate guanylyltransferase (NCBI ptt file) compare
BT0880 +1.3 2.2 hypothetical protein (NCBI ptt file) compare
BT0722 +1.3 2.2 conserved hypothetical protein, putative surface protein, function unknown (NCBI ptt file) compare
BT2038 +1.3 6.0 cation efflux system protein (NCBI ptt file) compare
BT4574 +1.3 3.3 conserved hypothetical protein (NCBI ptt file) compare
BT0729 +1.3 3.2 transcriptional regulator (NCBI ptt file) compare
BT3374 +1.3 5.4 putative carbamoyl-phosphate-synthetase (NCBI ptt file) compare
BT1347 +1.3 3.1 conserved hypothetical protein (NCBI ptt file) compare
BT2039 +1.3 4.1 cation efflux system protein, AcrB/AcrD/AcrF family protein (NCBI ptt file) compare
BT3887 +1.3 1.6 hypothetical protein (NCBI ptt file) compare
BT3806 +1.2 1.1 conserved hypothetical protein (NCBI ptt file) compare
BT0526 +1.2 3.4 L-asparaginase I (NCBI ptt file) compare
BT2136 +1.2 3.9 putative purple acid phosphatase (NCBI ptt file) compare
BT0006 +1.2 2.2 hypothetical protein (NCBI ptt file) compare
BT1080 +1.2 0.9 hypothetical protein (NCBI ptt file) compare
BT0924 +1.2 2.8 conserved hypothetical protein (NCBI ptt file) compare
BT0639 +1.2 1.8 conserved hypothetical protein (NCBI ptt file) compare
BT0279 +1.2 3.2 hypothetical protein (NCBI ptt file) compare
BT1701 +1.2 1.7 hypothetical protein (NCBI ptt file) compare
BT2448 +1.2 3.7 conserved hypothetical protein (NCBI ptt file) compare
BT2153 +1.2 2.2 putative Fe-S oxidoreductases (NCBI ptt file) compare
BT3268 +1.2 1.6 glucose-inhibited division protein A (NCBI ptt file) compare
BT1334 +1.2 3.5 PhoH-like protein (NCBI ptt file) compare
BT2976 +1.1 4.4 FKBP-type peptidyl-prolyl cis-trans isomerase, outer membrane protein precursor (NCBI ptt file) compare
BT1341 +1.1 3.9 UDP-glucose 6-dehydrogenase (NCBI ptt file) compare
BT1919 +1.1 3.0 conserved hypothetical protein with a conserved domain (NCBI ptt file) compare
BT0849 +1.1 3.3 hypothetical protein (NCBI ptt file) compare
BT0474 +1.1 2.9 D-glycero-D-manno-heptose 1-phosphate kinase (NCBI ptt file) compare
BT2418 +1.1 3.3 hypothetical protein (NCBI ptt file) compare
BT2755 +1.1 5.2 aspartate ammonia-lyase (NCBI ptt file) compare
BT3373 +1.1 2.9 spermidine n1-acetyltransferase (NCBI ptt file) compare
BT1852 +1.1 2.1 cysteine synthase A (NCBI ptt file) compare
BT3715 +1.1 4.8 hypothetical protein (NCBI ptt file) compare
BT3250 +1.1 3.9 conserved hypothetical protein (NCBI ptt file) compare
BT1221 +1.1 3.4 glucose-6-phosphate 1-dehydrogenase (NCBI ptt file) compare
BT4016 +1.1 3.5 hypothetical protein (NCBI ptt file) compare
BT1915 +1.1 3.1 pyruvate carboxylase subunit A (NCBI ptt file) compare
BT3999 +1.1 4.3 membrane-bound lytic murein transglycosylase D presursor (NCBI ptt file) compare
BT4421 +1.0 1.0 conserved hypothetical protein (NCBI ptt file) compare
BT3080 +1.0 4.3 cysteine synthase A (NCBI ptt file) compare
BT4027 +1.0 1.3 hypothetical protein (NCBI ptt file) compare
BT1613 +1.0 4.5 conserved hypothetical protein (NCBI ptt file) compare
BT4453 +1.0 1.5 6-pyruvoyl-tetrahydropterin synthase (NCBI ptt file) compare
BT2258 +1.0 3.2 GTP-binding protein (NCBI ptt file) compare
BT2328 +1.0 2.8 conserved hypothetical protein (NCBI ptt file) compare
BT4466 +1.0 1.4 hypothetical protein (NCBI ptt file) compare
BT1348 +1.0 3.4 CDP-abequose synthase (NCBI ptt file) compare
BT4390 +1.0 2.2 conserved hypothetical protein (NCBI ptt file) compare
BT3355 +1.0 0.5 putative auxin-regulated protein (NCBI ptt file) compare
BT0058 +1.0 1.7 hypothetical protein (NCBI ptt file) compare
BT2336 +1.0 1.9 conserved hypothetical protein (NCBI ptt file) compare
BT4698 +1.0 1.0 conserved hypothetical protein (NCBI ptt file) compare
BT0661 +1.0 3.9 hypothetical protein (NCBI ptt file) compare
BT2091 +1.0 3.4 methylmalonyl-CoA mutase small subunit (NCBI ptt file) compare
BT1115 +1.0 2.1 aldo/keto reductase (NCBI ptt file) compare
BT1464 +1.0 1.8 putative acetyltransferase, (GNAT) family (NCBI ptt file) compare
BT3168 +1.0 3.2 putative Fe-S oxidoreductase (NCBI ptt file) compare
BT1596 +1.0 3.0 putative sulfatase yidJ (NCBI ptt file) compare
BT4678 +1.0 4.0 L-serine dehydratase (NCBI ptt file) compare
BT0079 +1.0 1.8 putative anti-restriction protein (NCBI ptt file) compare
BT4195 +1.0 1.5 conserved hypothetical protein (NCBI ptt file) compare
BT0355 +1.0 3.5 L-arabinose/L-arabinobiose symporter (from data) compare
BT0521 +1.0 2.6 putative acetyl transferase (NCBI ptt file) compare
BT1077 +1.0 2.4 putative aspartate aminotransferase (NCBI ptt file) compare
BT3823 +0.9 2.7 conserved hypothetical protein (NCBI ptt file) compare
BT0932 +0.9 1.2 hypothetical protein (NCBI ptt file) compare
BT4490 +0.9 1.6 hypothetical protein (NCBI ptt file) compare
BT1176 +0.9 1.5 putative glycosyltransferase (NCBI ptt file) compare
BT0692 +0.9 1.4 putative calcineurin superfamily phosphohydrolase (NCBI ptt file) compare
BT4495 +0.9 3.4 conserved hypothetical protein (NCBI ptt file) compare
BT2886 +0.9 2.4 putative transcriptional regulator (NCBI ptt file) compare
BT0336 +0.9 3.5 conserved hypothetical protein (NCBI ptt file) compare
BT0951 +0.9 2.0 hypothetical protein (NCBI ptt file) compare
BT1482 +0.9 2.4 two-component system response regulator (NCBI ptt file) compare
BT1047 +0.9 2.6 hypothetical protein (NCBI ptt file) compare
BT1973 +0.9 4.6 NAD-specific glutamate dehydrogenase (NCBI ptt file) compare
BT0215 +0.9 0.9 iron uptake regulatory protein (NCBI ptt file) compare
BT1565 +0.9 1.5 hypothetical protein (NCBI ptt file) compare
BT4097 +0.9 0.8 Trk system K+ uptake protein trkH (NCBI ptt file) compare
BT4237 +0.9 2.0 tRNA pseudouridine synthase A (NCBI ptt file) compare
BT0466 +0.9 3.2 dTDP-glucose 4,6-dehydratase (NCBI ptt file) compare
BT1304 +0.9 0.8 putative transcriptional regulator (NCBI ptt file) compare
BT0734 +0.9 4.0 conserved hypothetical protein (NCBI ptt file) compare
BT0746 +0.9 1.6 putative zinc protease (NCBI ptt file) compare
BT0911 +0.9 3.5 putative integration host factor IHF alpha subunit (NCBI ptt file) compare
BT1651 +0.9 3.4 pyrophosphorylase (NCBI ptt file) compare
BT3369 +0.9 2.0 putative glycosyltransferase (NCBI ptt file) compare
BT4340 +0.9 2.7 hypothetical protein (NCBI ptt file) compare
BT4341 +0.9 3.7 hypothetical protein (NCBI ptt file) compare
BT1817 +0.9 2.2 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT4386 +0.9 0.9 hypoxanthine-guanine phosphoribosyltransferase (NCBI ptt file) compare
BT1521 +0.9 3.7 conserved hypothetical protein (NCBI ptt file) compare
BT0992 +0.9 3.0 beta-galactosidase (NCBI ptt file) compare
BT4212 +0.9 1.5 conserved hypothetical protein (NCBI ptt file) compare
BT1757 +0.9 2.9 fructokinase (NCBI ptt file) compare
BT0545 +0.9 1.3 nitrogen regulatory protein P-II (NCBI ptt file) compare
BT0866 +0.9 3.4 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) compare
BT2121 +0.9 3.5 putative Na+-driven multidrug efflux pump (NCBI ptt file) compare
BT3942 +0.9 2.7 conserved hypothetical protein (NCBI ptt file) compare
BT4562 +0.9 0.9 hypothetical protein (NCBI ptt file) compare
BT0016 +0.9 1.5 hypothetical protein (NCBI ptt file) compare
BT3663 +0.9 3.9 putative beta-xylosidase (NCBI ptt file) compare
BT3284 +0.9 1.4 conserved hypothetical protein (NCBI ptt file) compare
BT0478 +0.9 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT0543 +0.9 2.5 glutamine synthetase (NCBI ptt file) compare
BT1736 +0.9 1.5 chromate transport protein (NCBI ptt file) compare
BT0976 +0.9 3.9 putative transport protein (NCBI ptt file) compare
BT1142 +0.9 1.5 hypothetical protein (NCBI ptt file) compare
BT2985 +0.9 3.9 DNA repair protein (NCBI ptt file) compare
BT3372 +0.9 3.4 glycosyltransferase (NCBI ptt file) compare
BT0679 +0.9 1.5 cation efflux system protein czcB (NCBI ptt file) compare
BT3891 +0.8 0.6 hypothetical protein (NCBI ptt file) compare
BT0271 +0.8 2.2 hypothetical protein (NCBI ptt file) compare
BT0337 +0.8 1.8 conserved hypothetical protein (NCBI ptt file) compare
BT0376 +0.8 0.6 putative transcriptional regulator (NCBI ptt file) compare
BT0339 +0.8 2.6 alpha-glucosidase (NCBI ptt file) compare
BT0860 +0.8 0.8 putative ABC transporter ATP-binding protein (NCBI ptt file) compare
BT2287 +0.8 2.6 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT0603 +0.8 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT3591 +0.8 4.1 hypothetical protein (NCBI ptt file) compare
BT3821 +0.8 3.2 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) compare
BT2389 +0.8 1.1 putative transport protein (NCBI ptt file) compare
BT0220 +0.8 0.7 hypothetical protein (NCBI ptt file) compare
BT0705 +0.8 2.9 hypothetical protein (NCBI ptt file) compare
BT2228 +0.8 2.9 hypothetical protein (NCBI ptt file) compare
BT1713 +0.8 1.8 putative acylneuraminate cytidylyltransferase (NCBI ptt file) compare
BT0239 +0.8 2.3 hypothetical protein (NCBI ptt file) compare
BT2691 +0.8 1.7 methenyltetrahydrofolate cyclohydrolase (NCBI ptt file) compare
BT0085 +0.8 1.5 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT3303 +0.8 4.4 ATP-dependent RNA helicase (NCBI ptt file) compare
BT0568 +0.8 2.5 hypothetical protein (NCBI ptt file) compare
BT0558 +0.8 2.5 mannose-1-phosphate guanylyltransferase (NCBI ptt file) compare
BT2086 +0.8 2.5 choloylglycine hydrolase (NCBI ptt file) compare
BT3375 +0.8 3.2 aspartate aminotransferase (NCBI ptt file) compare
BT0656 +0.8 3.1 conserved hypothetical protein (NCBI ptt file) compare
BT2519 +0.8 1.7 putative glycine cleavage system H protein (NCBI ptt file) compare
BT2275 +0.8 2.1 thymidine kinase (NCBI ptt file) compare
BT3370 +0.8 1.9 putative glycosyltransferase yibD (NCBI ptt file) compare


Specific Phenotypes

For 9 genes in this experiment

For stress Simvastatin in Bacteroides thetaiotaomicron VPI-5482

For stress Simvastatin across organisms