Experiment set13S659 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete 3-nitroxypropanol 0.000416666666666667 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS08320 +4.0 14.7 molybdopterin molybdotransferase MoeA compare
MMP_RS07415 +4.0 14.8 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS02885 +3.9 30.0 molybdopterin biosynthesis protein compare
MMP_RS01370 +3.8 13.7 acetate--CoA ligase family protein compare
MMP_RS06705 +2.8 7.8 formate/nitrite transporter family protein compare
MMP_RS07955 +2.6 9.6 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS00750 +2.1 3.4 fumarate hydratase compare
MMP_RS01775 +2.1 2.1 TIGR00297 family protein compare
MMP_RS06720 +2.0 8.1 response regulator transcription factor compare
MMP_RS04605 +2.0 4.5 cobalt ECF transporter T component CbiQ compare
MMP_RS07075 +2.0 3.7 phosphomannomutase/phosphoglucomutase compare
MMP_RS07705 +2.0 6.9 transcriptional regulator compare
MMP_RS06715 +2.0 13.1 cache domain-containing protein compare
MMP_RS02410 +1.9 2.2 ABC transporter substrate-binding protein compare
MMP_RS05315 +1.9 3.0 hypothetical protein compare
MMP_RS02805 +1.9 2.2 HEPN domain-containing protein compare
MMP_RS08660 +1.8 5.2 DHH family phosphoesterase compare
MMP_RS02880 +1.8 5.7 AmmeMemoRadiSam system radical SAM enzyme compare
MMP_RS04695 +1.8 6.6 selenide water dikinase SelD compare
MMP_RS07960 +1.7 7.2 sugar phosphate isomerase/epimerase compare
MMP_RS02310 +1.7 2.8 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS03485 +1.7 3.7 TIGR00267 family protein compare
MMP_RS00325 +1.7 2.8 RNA-binding protein compare
MMP_RS08275 +1.6 7.1 hypothetical protein compare
MMP_RS08380 +1.6 2.5 phosphatase PAP2 family protein compare
MMP_RS08355 +1.4 3.0 Na(+)/H(+) antiporter subunit B compare
MMP_RS00675 +1.4 1.3 nitroreductase family protein compare
MMP_RS01890 +1.4 2.9 nucleotide sugar dehydrogenase compare
MMP_RS06670 +1.4 3.1 glucose-6-phosphate isomerase compare
MMP_RS02870 +1.4 8.1 hypothetical protein compare
MMP_RS05535 +1.3 3.9 hypothetical protein compare
MMP_RS01955 +1.3 1.4 hypothetical protein compare
MMP_RS07090 +1.3 3.4 tRNA (adenine-N1)-methyltransferase compare
MMP_RS07355 +1.2 1.1 transcription factor S compare
MMP_RS07890 +1.2 2.9 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS03320 +1.2 1.5 metal-dependent transcriptional regulator compare
MMP_RS04620 +1.2 5.0 cobalt transporter CbiM compare
MMP_RS04875 +1.2 2.3 energy-converting hydrogenase B subunit P compare
MMP_RS07725 +1.2 1.9 4Fe-4S dicluster domain-containing protein compare
MMP_RS08360 +1.1 2.9 hypothetical protein compare
MMP_RS06575 +1.1 1.7 fluoride efflux transporter CrcB compare
MMP_RS07555 +1.1 0.6 monovalent cation/H+ antiporter subunit E compare
MMP_RS07435 +1.1 1.7 GMP synthase subunit A compare
MMP_RS05460 +1.1 5.0 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS03495 +1.0 3.1 Na/Pi cotransporter family protein compare
MMP_RS08775 +1.0 4.3 methanogenesis marker 9 domain-containing protein compare
MMP_RS06525 +1.0 1.2 YciI family protein compare
MMP_RS06990 +1.0 2.7 CatB-related O-acetyltransferase compare
MMP_RS08340 +1.0 2.1 4Fe-4S binding protein compare
MMP_RS05850 +1.0 2.2 Ldh family oxidoreductase compare
MMP_RS03270 +1.0 2.5 ADP-ribosylglycohydrolase family protein compare
MMP_RS02010 +1.0 3.6 PHP domain-containing protein compare
MMP_RS00670 +1.0 2.6 TIM barrel protein compare
MMP_RS04015 +1.0 2.0 hypothetical protein compare
MMP_RS03420 +1.0 3.2 acetolactate synthase small subunit compare
MMP_RS07710 +1.0 2.2 cell division protein FtsZ compare
MMP_RS04615 +1.0 1.2 PDGLE domain-containing protein compare
MMP_RS06365 +0.9 2.0 hypothetical protein compare
MMP_RS06570 +0.9 2.6 DUF190 domain-containing protein compare
MMP_RS01210 +0.9 2.1 sodium:solute symporter compare
MMP_RS00120 +0.9 2.3 LysR family transcriptional regulator compare
MMP_RS01195 +0.9 1.0 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS02605 +0.9 0.8 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS05140 +0.9 2.1 helix-turn-helix transcriptional regulator compare
MMP_RS04055 +0.9 1.3 hypothetical protein compare
MMP_RS01830 +0.9 1.1 tRNA-Val compare
MMP_RS08335 +0.9 2.3 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS07420 +0.9 2.7 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS08070 +0.9 3.4 DUF2096 domain-containing protein compare
MMP_RS05550 +0.9 0.5 cation:proton antiporter compare
MMP_RS01865 +0.9 1.2 GPR1/FUN34/YaaH family transporter compare
MMP_RS07895 +0.9 2.5 cytochrome c compare
MMP_RS06130 +0.9 1.7 peptidylprolyl isomerase compare
MMP_RS08345 +0.9 3.2 4Fe-4S binding protein compare
MMP_RS05640 +0.9 2.3 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS03215 +0.9 2.8 MBL fold metallo-hydrolase compare
MMP_RS00530 +0.9 2.3 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS01660 +0.8 2.1 hypothetical protein compare
MMP_RS00125 +0.8 1.0 DUF2798 domain-containing protein compare
MMP_RS03675 +0.8 4.3 RimK family alpha-L-glutamate ligase compare
MMP_RS00760 +0.8 3.5 branched-chain-amino-acid transaminase compare
MMP_RS04720 +0.8 1.3 DedA family protein compare
MMP_RS03125 +0.8 2.9 cell division ATPase MinD compare
MMP_RS02290 +0.8 2.3 MBL fold metallo-hydrolase compare
MMP_RS01945 +0.8 2.6 DUF4350 domain-containing protein compare
MMP_RS00450 +0.8 0.9 4Fe-4S binding protein compare
MMP_RS06760 +0.8 2.4 hypothetical protein compare
MMP_RS03900 +0.8 2.0 minichromosome maintenance protein MCM compare
MMP_RS05720 +0.8 1.7 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS00345 +0.8 2.3 DUF2666 domain-containing protein compare
MMP_RS06535 +0.7 1.2 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS01150 +0.7 2.5 aldo/keto reductase compare
MMP_RS00150 +0.7 2.3 AAA family ATPase compare
MMP_RS02355 +0.7 0.8 30S ribosomal protein S27ae compare
MMP_RS04740 +0.7 2.3 DUF473 domain-containing protein compare
MMP_RS02045 +0.7 0.9 tRNA-Met compare
MMP_RS01910 +0.7 2.6 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS01880 +0.7 2.2 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01875 +0.7 2.6 N-acetyltransferase compare
MMP_RS03770 +0.7 3.3 hydroxylamine reductase compare
MMP_RS01190 +0.7 2.0 cadmium-translocating P-type ATPase compare
MMP_RS08205 +0.7 3.6 stage II sporulation protein M compare
MMP_RS01685 +0.7 1.5 indolepyruvate oxidoreductase subunit beta compare
MMP_RS07130 +0.7 3.7 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS02130 +0.7 1.9 zinc metalloprotease HtpX compare
MMP_RS02415 +0.7 1.1 site-specific integrase compare
MMP_RS08930 +0.6 0.5 hypothetical protein compare
MMP_RS07900 +0.6 0.8 YeeE/YedE family protein compare
MMP_RS06860 +0.6 0.9 4Fe-4S binding protein compare
MMP_RS05365 +0.6 1.3 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS01940 +0.6 1.0 MoxR family ATPase compare
MMP_RS07850 +0.6 0.9 prephenate dehydratase compare
MMP_RS05950 +0.6 2.3 nickel-dependent hydrogenase large subunit compare
MMP_RS03875 +0.6 1.1 hypothetical protein compare
MMP_RS01240 +0.6 0.8 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS07800 +0.6 2.4 ATP-binding cassette domain-containing protein compare
MMP_RS08615 +0.6 1.0 flagellar protein G compare
MMP_RS04100 +0.6 0.7 hypothetical protein compare
MMP_RS06050 +0.6 2.3 ZIP family metal transporter compare
MMP_RS03085 +0.6 2.5 endonuclease III compare
MMP_RS05900 +0.6 1.9 tetratricopeptide repeat protein compare
MMP_RS05175 +0.6 1.1 hypothetical protein compare
MMP_RS05940 +0.6 1.9 corrinoid protein compare
MMP_RS00535 +0.6 1.0 TIGR00375 family protein compare
MMP_RS05685 +0.6 1.5 winged helix-turn-helix domain-containing protein compare
MMP_RS00795 +0.6 2.0 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS09050 +0.5 0.8 CAP domain-containing protein compare
MMP_RS07885 +0.5 1.4 tripartite tricarboxylate transporter permease compare
MMP_RS01465 +0.5 0.6 hypothetical protein compare
MMP_RS01275 +0.5 1.0 class III signal peptide-containing protein compare
MMP_RS06770 +0.5 1.8 DHH family phosphoesterase compare
MMP_RS00940 +0.5 1.7 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS00960 +0.5 0.9 iron export ABC transporter permease subunit FetB compare
MMP_RS08395 +0.5 1.5 DsrE family protein compare
MMP_RS01895 +0.5 2.2 flippase compare
MMP_RS05680 +0.5 2.1 phosphate signaling complex protein PhoU compare
MMP_RS03405 +0.5 1.5 RNA 3'-terminal phosphate cyclase compare
MMP_RS04305 +0.5 0.6 hypothetical protein compare
MMP_RS01270 +0.5 2.6 prepilin peptidase compare
MMP_RS01310 +0.5 2.6 hypothetical protein compare
MMP_RS07835 +0.5 1.5 TldD/PmbA family protein compare
MMP_RS01905 +0.5 2.4 glycosyltransferase compare
MMP_RS08075 +0.5 1.4 DUF749 domain-containing protein compare
MMP_RS07820 +0.5 1.0 UPF0104 family protein compare
MMP_RS05450 +0.5 0.9 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS01605 +0.5 1.4 hypothetical protein compare
MMP_RS01580 +0.5 1.5 PQQ-binding-like beta-propeller repeat protein compare
MMP_RS01975 +0.5 2.5 hypothetical protein compare
MMP_RS03250 +0.5 1.1 MJ1244 family protein compare
MMP_RS01155 +0.5 1.4 XRE family transcriptional regulator compare
MMP_RS07570 +0.5 2.7 nucleotidyltransferase family protein compare
MMP_RS03150 +0.5 1.6 phosphoglycerate mutase compare
MMP_RS06310 +0.5 0.8 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS09045 +0.5 2.7 class III signal peptide-containing protein compare
MMP_RS08455 +0.5 1.1 multiprotein bridging factor aMBF1 compare
MMP_RS01430 +0.5 2.0 mechanosensitive ion channel family protein compare
MMP_RS01970 +0.5 2.3 TIGR04279 domain-containing protein compare
MMP_RS05660 +0.5 2.5 phosphate ABC transporter substrate-binding protein compare
MMP_RS02765 +0.5 0.9 ABC transporter ATP-binding protein compare
MMP_RS07135 +0.5 1.8 coenzyme F420 hydrogenase subunit beta compare
MMP_RS03685 +0.5 2.4 Mrp/NBP35 family ATP-binding protein compare
MMP_RS07190 +0.5 1.4 chromosome segregation protein SMC compare
MMP_RS00985 +0.5 1.3 CDC48 family AAA ATPase compare
MMP_RS03540 +0.5 1.3 DUF2178 domain-containing protein compare
MMP_RS01725 +0.5 0.8 class I SAM-dependent methyltransferase family protein compare
MMP_RS07155 +0.5 1.6 MFS transporter compare
MMP_RS01305 +0.5 3.1 hypothetical protein compare
MMP_RS09060 +0.5 1.8 hypothetical protein compare
MMP_RS01515 +0.5 2.0 PINc/VapC family ATPase compare
MMP_RS02785 +0.5 1.7 MarR family transcriptional regulator compare
MMP_RS03090 +0.5 1.0 cation:proton antiporter compare
MMP_RS04105 +0.5 1.7 MarR family transcriptional regulator compare
MMP_RS07095 +0.4 1.1 PspC domain-containing protein compare
MMP_RS02800 +0.4 1.3 nucleotidyltransferase domain-containing protein compare
MMP_RS06745 +0.4 0.8 DUF2119 domain-containing protein compare
MMP_RS02790 +0.4 0.4 class III signal peptide-containing protein compare
MMP_RS03480 +0.4 2.0 SulP family inorganic anion transporter compare
MMP_RS04325 +0.4 1.1 MtaA/CmuA family methyltransferase compare
MMP_RS02530 +0.4 1.9 type II toxin-antitoxin system mRNA interferase toxin RelE/StbE family compare
MMP_RS00965 +0.4 1.1 hypothetical protein compare
MMP_RS02645 +0.4 2.0 ArsR family transcriptional regulator compare
MMP_RS04125 +0.4 1.2 TetR/AcrR family transcriptional regulator compare
MMP_RS02710 +0.4 2.4 formylmethanofuran dehydrogenase subunit B compare
MMP_RS03430 +0.4 2.3 bile acid:sodium symporter family protein compare
MMP_RS08250 +0.4 1.8 pyruvate kinase compare
MMP_RS01415 +0.4 1.4 DUF2067 domain-containing protein compare
MMP_RS04035 +0.4 1.0 hypothetical protein compare
MMP_RS06375 +0.4 1.0 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS00235 +0.4 1.9 HDIG domain-containing protein compare
MMP_RS07410 +0.4 1.5 4-demethylwyosine synthase TYW1 compare
MMP_RS01855 +0.4 1.3 2-hydroxyacyl-CoA dehydratase family protein compare
MMP_RS02450 +0.4 1.3 hypothetical protein compare
MMP_RS07815 +0.4 0.4 DUF2120 domain-containing protein compare
MMP_RS04050 +0.4 1.0 hypothetical protein compare
MMP_RS05310 +0.4 1.8 hypothetical protein compare
MMP_RS08400 +0.4 0.9 MJ0307 family thioredoxin compare
MMP_RS02675 +0.4 0.6 hypothetical protein compare
MMP_RS06060 +0.4 1.6 hypothetical protein compare
MMP_RS01925 +0.4 1.5 DUF1616 domain-containing protein compare
MMP_RS07855 +0.4 1.5 class I SAM-dependent methyltransferase compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress 3-nitroxypropanol across organisms