Experiment set13S650 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Novobiocin sodium salt 0.025 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS06400 -4.3 -1.0 4Fe-4S binding protein compare
MMP_RS08790 -4.1 -2.2 translation initiation factor IF-2 subunit alpha compare
MMP_RS01500 -4.0 -1.7 CBS domain-containing protein compare
MMP_RS03445 -4.0 -0.8 methanogenesis marker 17 protein compare
MMP_RS02900 -4.0 -0.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS00520 -3.9 -1.5 RNA polymerase Rpb4 family protein compare
MMP_RS06730 -3.8 -2.0 phosphopantothenate/pantothenate synthetase compare
MMP_RS03315 -3.7 -0.8 ferrous iron transport protein A compare
MMP_RS06285 -3.6 -1.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS00515 -3.5 -0.7 DUF655 domain-containing protein compare
MMP_RS02175 -3.4 -0.8 DUF1611 domain-containing protein compare
MMP_RS06600 -3.3 -1.1 class III signal peptide-containing protein compare
MMP_RS08300 -3.3 -0.8 metal-sulfur cluster assembly factor compare
MMP_RS03205 -3.3 -1.2 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS01795 -3.2 -1.2 methanogenesis marker 6 protein compare
MMP_RS01005 -3.2 -0.9 riboflavin synthase compare
MMP_RS09020 -3.2 -1.2 hypothetical protein compare
MMP_RS08460 -3.1 -2.7 proteasome-activating nucleotidase compare
MMP_RS06015 -3.1 -10.0 flavodoxin family protein compare
MMP_RS07845 -3.0 -1.4 LL-diaminopimelate aminotransferase compare
MMP_RS06290 -3.0 -5.2 DNA repair and recombination protein RadA compare
MMP_RS01755 -3.0 -0.8 DUF2097 domain-containing protein compare
MMP_RS00685 -3.0 -3.0 2-phospho-L-lactate guanylyltransferase compare
MMP_RS06840 -3.0 -0.9 DNA-directed RNA polymerase subunit N compare
MMP_RS03580 -2.9 -3.0 signal recognition particle-docking protein FtsY compare
MMP_RS01380 -2.9 -4.0 PHP domain-containing protein compare
MMP_RS06110 -2.9 -3.5 ATP-dependent protease LonB compare
MMP_RS06230 -2.8 -2.2 helix-turn-helix domain-containing protein compare
MMP_RS08635 -2.8 -1.5 UbiA family prenyltransferase compare
MMP_RS02875 -2.7 -9.4 chorismate pyruvate-lyase family protein compare
MMP_RS07635 -2.7 -5.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08785 -2.7 -0.9 RNA-protein complex protein Nop10 compare
MMP_RS01020 -2.6 -0.8 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS08720 -2.6 -1.2 4Fe-4S binding protein compare
MMP_RS03435 -2.6 -1.5 ketol-acid reductoisomerase compare
MMP_RS01325 -2.6 -1.6 dihydroneopterin aldolase family protein compare
MMP_RS05430 -2.5 -5.9 TIGR00288 family NYN domain-containing protein compare
MMP_RS03640 -2.5 -2.5 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS03960 -2.5 -0.8 hypothetical protein compare
MMP_RS04485 -2.5 -10.4 putative beta-lysine N-acetyltransferase compare
MMP_RS00735 -2.5 -4.8 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS06355 -2.4 -2.0 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS07620 -2.4 -3.7 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS07380 -2.4 -1.8 transcription elongation factor Spt5 compare
MMP_RS00130 -2.4 -1.0 nickel-responsive transcriptional regulator NikR compare
MMP_RS01365 -2.4 -3.3 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07545 -2.3 -0.6 HTH domain-containing protein compare
MMP_RS00110 -2.3 -2.0 hypothetical protein compare
MMP_RS01175 -2.3 -2.3 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08645 -2.3 -6.0 UPF0179 family protein compare
MMP_RS05765 -2.2 -4.6 M42 family metallopeptidase compare
MMP_RS04780 -2.2 -2.2 ribonuclease P compare
MMP_RS08715 -2.2 -1.4 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06395 -2.2 -2.8 ThiF family adenylyltransferase compare
MMP_RS01265 -2.2 -2.1 hypothetical protein compare
MMP_RS06725 -2.2 -8.4 hypothetical protein compare
MMP_RS03490 -2.0 -1.4 DUF2115 domain-containing protein compare
MMP_RS08210 -2.0 -1.5 phosphatidylglycerophosphatase A compare
MMP_RS07200 -2.0 -5.1 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05550 -2.0 -0.5 cation:proton antiporter compare
MMP_RS03400 -2.0 -1.6 archease compare
MMP_RS06175 -2.0 -5.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS01700 -2.0 -0.8 dihydroxy-acid dehydratase compare
MMP_RS09025 -1.9 -0.9 hypothetical protein compare
MMP_RS08435 -1.9 -1.5 Era-like GTP-binding protein compare
MMP_RS04890 -1.9 -0.7 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS00725 -1.9 -4.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS05515 -1.9 -4.2 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS04685 -1.9 -1.9 DUF126 domain-containing protein compare
MMP_RS07730 -1.9 -1.4 pyruvate synthase subunit beta compare
MMP_RS08570 -1.8 -6.2 coenzyme F420-0:L-glutamate ligase compare
MMP_RS03520 -1.8 -1.7 YwbE family protein compare
MMP_RS04585 -1.8 -6.7 AIR synthase related protein compare
MMP_RS00730 -1.7 -3.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS06020 -1.7 -2.4 archaeoflavoprotein AfpA compare
MMP_RS07695 -1.7 -4.5 DUF3236 domain-containing protein compare
MMP_RS03700 -1.7 -6.3 sodium:proton antiporter compare
MMP_RS00305 -1.7 -1.3 phosphoribosyl-ATP diphosphatase compare
MMP_RS06975 -1.7 -1.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS04090 -1.7 -2.0 hypothetical protein compare
MMP_RS08225 -1.7 -6.0 RimK family alpha-L-glutamate ligase compare
MMP_RS06625 -1.6 -1.2 DNA primase compare
MMP_RS03555 -1.6 -5.6 transcriptional regulator compare
MMP_RS07355 -1.6 -0.7 transcription factor S compare
MMP_RS01800 -1.6 -2.5 TIGR00303 family protein compare
MMP_RS04850 -1.6 -8.2 UPF0254 family protein compare
MMP_RS06295 -1.6 -3.9 methanogenesis marker 14 protein compare
MMP_RS08820 -1.6 -3.8 hypothetical protein compare
MMP_RS04710 -1.6 -1.0 hypothetical protein compare
MMP_RS07445 -1.6 -4.1 helix-turn-helix domain-containing protein compare
MMP_RS08650 -1.6 -2.3 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS03600 -1.6 -1.2 triose-phosphate isomerase compare
MMP_RS07700 -1.6 -5.4 DUF1188 domain-containing protein compare
MMP_RS06350 -1.6 -3.4 HesA/MoeB/ThiF family protein compare
MMP_RS07615 -1.6 -4.5 energy-coupling factor ABC transporter permease compare
MMP_RS02240 -1.5 -2.0 methanogenesis marker 7 protein compare
MMP_RS05865 -1.5 -1.8 hypothetical protein compare
MMP_RS06120 -1.5 -1.4 UPF0147 family protein compare
MMP_RS07710 -1.5 -4.4 cell division protein FtsZ compare
MMP_RS05285 -1.4 -4.9 MMPL family transporter compare
MMP_RS08580 -1.4 -3.9 flagellin compare
MMP_RS01155 -1.4 -4.2 XRE family transcriptional regulator compare
MMP_RS07625 -1.4 -2.1 cobalt ECF transporter T component CbiQ compare
MMP_RS07765 -1.4 -4.4 sodium:alanine symporter family protein compare
MMP_RS06735 -1.4 -4.3 class I SAM-dependent rRNA methyltransferase compare
MMP_RS03015 -1.4 -5.1 GTP 3' 8-cyclase MoaA compare
MMP_RS08940 -1.3 -0.9 MetS family NSS transporter small subunit compare
MMP_RS05090 -1.3 -5.6 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS06270 -1.3 -2.6 TIGR00300 family protein compare
MMP_RS00040 -1.3 -4.2 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS04015 -1.3 -2.0 hypothetical protein compare
MMP_RS05295 -1.3 -6.0 minichromosome maintenance protein MCM compare
MMP_RS03080 -1.3 -2.4 universal stress protein compare
MMP_RS01285 -1.3 -5.8 hypothetical protein compare
MMP_RS01290 -1.3 -5.1 class III signal peptide-containing protein compare
MMP_RS05020 -1.3 -2.3 hypothetical protein compare
MMP_RS00570 -1.3 -1.9 protein-L-isoaspartate O-methyltransferase compare
MMP_RS01985 -1.3 -3.0 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS01610 -1.3 -1.5 hypothetical protein compare
MMP_RS02545 -1.3 -2.1 hypothetical protein compare
MMP_RS00535 -1.2 -1.9 TIGR00375 family protein compare
MMP_RS06885 -1.2 -1.2 50S ribosome-binding GTPase compare
MMP_RS08750 -1.2 -1.1 hypothetical protein compare
MMP_RS05920 -1.2 -0.3 50S ribosomal protein L37e compare
MMP_RS08675 -1.2 -1.4 class III signal peptide-containing protein compare
MMP_RS02745 -1.2 -1.5 hypothetical protein compare
MMP_RS03245 -1.2 -3.1 DNA repair and recombination protein RadB compare
MMP_RS03035 -1.2 -2.4 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS07425 -1.2 -2.7 GTP-binding protein compare
MMP_RS05545 -1.2 -2.6 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS04870 -1.2 -3.0 TIGR02253 family HAD-type hydrolase compare
MMP_RS05280 -1.2 -5.0 COG1361 S-layer family protein compare
MMP_RS08855 -1.2 -4.4 hypothetical protein compare
MMP_RS06865 -1.1 -1.3 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS06200 -1.1 -3.9 M24 family metallopeptidase compare
MMP_RS03025 -1.1 -2.5 molybdenum cofactor guanylyltransferase compare
MMP_RS03125 -1.1 -3.4 cell division ATPase MinD compare
MMP_RS05265 -1.1 -1.0 2-isopropylmalate synthase compare
MMP_RS01295 -1.1 -5.4 hypothetical protein compare
MMP_RS05845 -1.1 -1.0 tRNA-intron lyase compare
MMP_RS05290 -1.1 -3.0 TetR/AcrR family transcriptional regulator compare
MMP_RS01280 -1.1 -5.9 DUF515 domain-containing protein compare
MMP_RS00245 -1.1 -6.5 type II secretion system F family protein compare
MMP_RS01195 -1.1 -0.7 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS07115 -1.1 -2.5 MBL fold metallo-hydrolase compare
MMP_RS00240 -1.1 -7.1 type II secretion system F family protein compare
MMP_RS07600 -1.1 -0.9 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS05060 -1.1 -4.8 AAA family ATPase compare
MMP_RS06315 -1.0 -0.5 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS00900 -1.0 -1.1 50S ribosomal protein L39e compare
MMP_RS01275 -1.0 -2.7 class III signal peptide-containing protein compare
MMP_RS07540 -1.0 -2.4 CBS domain-containing protein compare
MMP_RS08860 -1.0 -2.9 MinD/ParA family protein compare
MMP_RS07580 -1.0 -1.3 DUF356 domain-containing protein compare
MMP_RS03305 -1.0 -3.3 winged helix-turn-helix domain-containing protein compare
MMP_RS02995 -1.0 -2.5 acyl-CoA thioesterase compare
MMP_RS01305 -1.0 -6.5 hypothetical protein compare
MMP_RS04990 -1.0 -2.6 aquaporin family protein compare
MMP_RS00695 -0.9 -0.4 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00250 -0.9 -5.9 Flp pilus assembly complex ATPase component TadA compare
MMP_RS01445 -0.9 -2.5 hypothetical protein compare
MMP_RS01270 -0.9 -5.8 prepilin peptidase compare
MMP_RS05080 -0.9 -4.5 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS00895 -0.9 -1.0 hypothetical protein compare
MMP_RS05875 -0.9 -1.6 hydroxyethylthiazole kinase compare
MMP_RS07365 -0.9 -5.0 2-phosphoglycerate kinase compare
MMP_RS08195 -0.9 -2.8 hypothetical protein compare
MMP_RS07525 -0.9 -3.0 4Fe-4S binding protein compare
MMP_RS03800 -0.9 -1.5 hypothetical protein compare
MMP_RS06215 -0.9 -1.1 30S ribosomal protein S6e compare
MMP_RS06095 -0.9 -3.0 ABC transporter ATP-binding protein compare
MMP_RS02170 -0.9 -1.6 CBS domain-containing protein compare
MMP_RS04410 -0.9 -1.5 hypothetical protein compare
MMP_RS06605 -0.9 -4.1 DUF5814 domain-containing protein compare
MMP_RS07735 -0.9 -0.3 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS05635 -0.8 -3.3 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS04595 -0.8 -2.1 hypothetical protein compare
MMP_RS05070 -0.8 -2.8 4Fe-4S dicluster domain-containing protein compare
MMP_RS01310 -0.8 -5.0 hypothetical protein compare
MMP_RS04060 -0.8 -2.0 hypothetical protein compare
MMP_RS03550 -0.8 -1.0 DUF2124 domain-containing protein compare
MMP_RS01075 -0.8 -0.9 hypothetical protein compare
MMP_RS01720 -0.8 -0.8 replication factor C large subunit compare
MMP_RS01655 -0.8 -1.1 DsrE family protein compare
MMP_RS04480 -0.8 -3.7 lysine 2 3-aminomutase compare
MMP_RS08830 -0.8 -2.4 GTP-binding protein compare
MMP_RS03140 -0.8 -2.6 hypothetical protein compare
MMP_RS04985 -0.8 -1.8 DUF2180 family protein compare
MMP_RS02905 -0.8 -1.3 2-thiouracil desulfurase family protein compare
MMP_RS07385 -0.7 -0.9 protein translocase SEC61 complex subunit gamma compare
MMP_RS03105 -0.7 -3.4 radical SAM protein compare
MMP_RS04980 -0.7 -4.3 DUF2193 domain-containing protein compare
MMP_RS02280 -0.7 -0.4 DUF211 domain-containing protein compare
MMP_RS05075 -0.7 -4.4 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS01455 -0.7 -2.5 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS02720 -0.7 -1.5 molybdate ABC transporter substrate-binding protein compare
MMP_RS05100 -0.7 -4.4 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS04610 -0.7 -1.2 Dabb family protein compare
MMP_RS05535 -0.7 -1.5 hypothetical protein compare
MMP_RS00315 -0.7 -1.9 Nif3-like dinuclear metal center hexameric protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Novobiocin sodium salt across organisms