Experiment set13S630 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS07860		-2.0	-1.0	hypothetical protein
MMP_RS02900		-2.0	-0.8	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS08940		-1.5	-1.5	MetS family NSS transporter small subunit
MMP_RS08635		-1.4	-1.5	UbiA family prenyltransferase
MMP_RS04090		-1.3	-1.3	hypothetical protein
MMP_RS03450		-1.2	-2.2	glycine synthesis protein GlyXS (from data)
MMP_RS01100		-1.1	-1.4	ABC transporter ATP-binding protein
MMP_RS08300		-1.1	-1.0	metal-sulfur cluster assembly factor
MMP_RS00300		-1.0	-0.5	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS06230		-1.0	-1.0	helix-turn-helix domain-containing protein
MMP_RS06840		-0.9	-0.8	DNA-directed RNA polymerase subunit N
MMP_RS07730		-0.9	-0.9	pyruvate synthase subunit beta
MMP_RS06735		-0.9	-1.8	class I SAM-dependent rRNA methyltransferase
MMP_RS08775		-0.8	-3.4	methanogenesis marker 9 domain-containing protein
MMP_RS09055		-0.8	-0.7	CAP domain-containing protein
MMP_RS04100		-0.8	-1.1	hypothetical protein
MMP_RS00670		-0.8	-2.7	TIM barrel protein
MMP_RS01635		-0.8	-2.0	thiamine pyrophosphate-dependent enzyme
MMP_RS01110		-0.8	-1.3	FmdE family protein
MMP_RS02905		-0.7	-1.6	2-thiouracil desulfurase family protein
MMP_RS06905		-0.7	-1.0	hypothetical protein
MMP_RS00395		-0.7	-1.1	MGMT family protein
MMP_RS08350		-0.7	-0.7	hypothetical protein
MMP_RS05555		-0.7	-0.9	DUF4040 domain-containing protein
MMP_RS00110		-0.7	-1.0	hypothetical protein
MMP_RS07905		-0.7	-1.7	DUF3343 domain-containing protein
MMP_RS03320		-0.7	-1.7	metal-dependent transcriptional regulator
MMP_RS01440		-0.7	-3.4	NAAT family transporter
MMP_RS08860		-0.7	-1.9	MinD/ParA family protein
MMP_RS01865		-0.7	-1.0	GPR1/FUN34/YaaH family transporter
MMP_RS07390		-0.7	-0.9	cell division protein FtsZ
MMP_RS03125		-0.7	-1.8	cell division ATPase MinD
MMP_RS07625		-0.6	-1.2	cobalt ECF transporter T component CbiQ
MMP_RS05355		-0.6	-0.6	hypothetical protein
MMP_RS04060		-0.6	-2.1	hypothetical protein
MMP_RS06535		-0.6	-1.3	2-oxoacid:acceptor oxidoreductase family protein
MMP_RS06475		-0.6	-1.1	FAD-dependent oxidoreductase
MMP_RS06225		-0.6	-2.6	DNA double-strand break repair nuclease NurA
MMP_RS07540		-0.6	-1.3	CBS domain-containing protein
MMP_RS05550		-0.6	-0.3	cation:proton antiporter
MMP_RS06400		-0.6	-0.5	4Fe-4S binding protein
MMP_RS04410		-0.6	-1.4	hypothetical protein
MMP_RS01095		-0.6	-1.7	iron ABC transporter permease
MMP_RS01960		-0.6	-0.5	hypothetical protein
MMP_RS06965		-0.6	-2.6	TIGR04014 family B12-binding domain/radical SAM domain-containing protein
MMP_RS09050		-0.6	-2.1	CAP domain-containing protein
MMP_RS02495		-0.6	-1.3	hypothetical protein
MMP_RS01385		-0.6	-0.3	imidazole glycerol phosphate synthase subunit HisH
MMP_RS04145		-0.6	-0.9	hypothetical protein
MMP_RS01620		-0.6	-2.1	hypothetical protein
MMP_RS04985		-0.5	-1.4	DUF2180 family protein
MMP_RS05930		-0.5	-0.7	3-isopropylmalate dehydratase large subunit
MMP_RS02025		-0.5	-3.4	DNA-directed DNA polymerase
MMP_RS04035		-0.5	-0.9	hypothetical protein
MMP_RS07335		-0.5	-1.6	tRNA (cytidine(56)-2'-O)-methyltransferase
MMP_RS04475		-0.5	-1.8	nitrogen fixation
MMP_RS01540		-0.5	-1.4	DUF504 domain-containing protein
MMP_RS00515		-0.5	-0.5	DUF655 domain-containing protein
MMP_RS06045		-0.5	-2.2	DNA polymerase
MMP_RS07845		-0.5	-0.3	LL-diaminopimelate aminotransferase
MMP_RS03080		-0.5	-0.9	universal stress protein
MMP_RS01745		-0.5	-1.1	AMP phosphorylase
MMP_RS06975		-0.5	-0.8	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS04520		-0.5	-1.1	nucleoside deaminase
MMP_RS07130		-0.5	-2.7	coenzyme F420 hydrogenase subunit gamma
MMP_RS00895		-0.5	-0.8	hypothetical protein
MMP_RS02370		-0.5	-1.6	NifB/NifX family molybdenum-iron cluster-binding protein
MMP_RS07795		-0.5	-2.7	site-2 protease family protein
MMP_RS07725		-0.5	-1.8	4Fe-4S dicluster domain-containing protein
MMP_RS01485		-0.5	-2.4	right-handed parallel beta-helix repeat-containing protein
MMP_RS03235		-0.5	-1.4	tRNA pseudouridine(13) synthase TruD
MMP_RS03330		-0.4	-2.7	rubrerythrin family protein
MMP_RS08645		-0.4	-1.6	UPF0179 family protein
MMP_RS07955		-0.4	-1.7	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS08480		-0.4	-1.9	molybdate ABC transporter substrate-binding protein
MMP_RS03215		-0.4	-2.1	MBL fold metallo-hydrolase
MMP_RS05435		-0.4	-1.8	5'/3'-nucleotidase SurE
MMP_RS02965		-0.4	-1.2	carboxymuconolactone decarboxylase family protein
MMP_RS05490		-0.4	-2.0	IMPACT family protein
MMP_RS07150		-0.4	-1.5	MTH895/ArsE family thioredoxin-like protein
MMP_RS00135		-0.4	-2.2	DUF2121 domain-containing protein
MMP_RS08675		-0.4	-0.9	class III signal peptide-containing protein
MMP_RS02785		-0.4	-2.1	MarR family transcriptional regulator
MMP_RS05660		-0.4	-1.8	phosphate ABC transporter substrate-binding protein
MMP_RS02745		-0.4	-0.9	hypothetical protein
MMP_RS01240		-0.4	-0.7	7-cyano-7-deazaguanine synthase QueC
MMP_RS04325		-0.4	-1.6	MtaA/CmuA family methyltransferase
MMP_RS06990		-0.4	-1.6	CatB-related O-acetyltransferase
MMP_RS08260		-0.4	-2.3	DUF99 family protein
MMP_RS02360		-0.4	-1.6	hypothetical protein
MMP_RS02425		-0.4	-1.5	hypothetical protein
MMP_RS08760		-0.4	-1.2	hypothetical protein
MMP_RS01365		-0.4	-1.0	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS08600		-0.4	-0.6	flagellar protein D
MMP_RS08330		-0.4	-1.4	NADH-quinone oxidoreductase subunit H
MMP_RS05850		-0.4	-1.1	Ldh family oxidoreductase
MMP_RS01280		-0.4	-3.0	DUF515 domain-containing protein
MMP_RS08075		-0.4	-1.3	DUF749 domain-containing protein
MMP_RS07550		-0.4	-2.0	L-serine ammonia-lyase iron-sulfur-dependent subunit alpha
MMP_RS05990		-0.4	-0.8	DsrE family protein
MMP_RS01785		-0.4	-1.9	hypothetical protein
MMP_RS01655		-0.4	-0.9	DsrE family protein
MMP_RS05835		-0.4	-0.3	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS08470		-0.4	-1.6	ATP-binding cassette domain-containing protein
MMP_RS05715		-0.4	-1.7	hypothetical protein
MMP_RS01275		-0.4	-1.4	class III signal peptide-containing protein
MMP_RS08570		-0.3	-1.8	coenzyme F420-0:L-glutamate ligase
MMP_RS01120		-0.3	-2.0	permease
MMP_RS01450		-0.3	-1.8	tRNA pseudouridine(38-40) synthase TruA
MMP_RS01860		-0.3	-1.7	hypothetical protein
MMP_RS04320		-0.3	-2.5	uroporphyrinogen decarboxylase family protein
MMP_RS00700		-0.3	-0.9	OB-fold nucleic acid binding domain-containing protein
MMP_RS06050		-0.3	-1.7	ZIP family metal transporter
MMP_RS00735		-0.3	-1.7	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS03315		-0.3	-0.2	ferrous iron transport protein A
MMP_RS08785		-0.3	-0.4	RNA-protein complex protein Nop10
MMP_RS03900		-0.3	-1.9	minichromosome maintenance protein MCM
MMP_RS02550		-0.3	-1.1	helix-turn-helix transcriptional regulator
MMP_RS05845		-0.3	-0.5	tRNA-intron lyase
MMP_RS03625		-0.3	-1.5	cell wall-binding protein
MMP_RS07650		-0.3	-1.5	TldD/PmbA family protein
MMP_RS02540		-0.3	-1.2	DUF2283 domain-containing protein
MMP_RS01305		-0.3	-2.5	hypothetical protein
MMP_RS08400		-0.3	-0.8	MJ0307 family thioredoxin
MMP_RS03990		-0.3	-1.0	recombinase family protein
MMP_RS01460		-0.3	-0.6	hypothetical protein
MMP_RS03590		-0.3	-1.2	METTL5 family protein
MMP_RS03340		-0.3	-0.3	ABC transporter ATP-binding protein
MMP_RS05720		-0.3	-0.9	signal recognition particle subunit SRP19/SEC65 family protein
MMP_RS08070		-0.3	-0.8	DUF2096 domain-containing protein
MMP_RS01295		-0.3	-1.6	hypothetical protein
MMP_RS02575		-0.3	-1.5	CAAX prenyl protease Rce1
MMP_RS00570		-0.3	-1.0	protein-L-isoaspartate O-methyltransferase
MMP_RS03520		-0.3	-0.7	YwbE family protein
MMP_RS01470		-0.3	-0.8	ATP-binding cassette domain-containing protein
MMP_RS00240		-0.3	-2.3	type II secretion system F family protein
MMP_RS07910		-0.3	-1.8	NAD(P)H-hydrate dehydratase
MMP_RS05430		-0.3	-1.3	TIGR00288 family NYN domain-containing protein
MMP_RS00335		-0.3	-1.1	5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
MMP_RS08990		-0.3	-1.1	hypothetical protein
MMP_RS00950		-0.3	-1.0	site-2 protease family protein
MMP_RS00185		-0.3	-1.9	potassium channel protein
MMP_RS04130		-0.3	-2.1	alpha/beta hydrolase
MMP_RS06085		-0.3	-2.3	iron ABC transporter substrate-binding protein
MMP_RS01160		-0.3	-1.3	DMT family transporter
MMP_RS06015		-0.3	-1.3	flavodoxin family protein
MMP_RS07615		-0.3	-1.0	energy-coupling factor ABC transporter permease
MMP_RS05800		-0.3	-1.3	B12-binding domain-containing radical SAM protein
MMP_RS03020		-0.3	-0.8	peptidylprolyl isomerase
MMP_RS02695		-0.3	-1.3	formylmethanofuran dehydrogenase subunit A
MMP_RS06745		-0.3	-1.1	DUF2119 domain-containing protein
MMP_RS04470		-0.3	-1.8	nitrogenase
MMP_RS06395		-0.3	-0.8	ThiF family adenylyltransferase
MMP_RS01575		-0.3	-1.5	aldolase
MMP_RS00245		-0.3	-2.2	type II secretion system F family protein
MMP_RS05770		-0.3	-1.3	YkgJ family cysteine cluster protein
MMP_RS05970		-0.3	-0.6	class II SORL domain-containing protein
MMP_RS00695		-0.3	-0.3	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS04335		-0.3	-1.6	GTP-binding protein
MMP_RS01315		-0.3	-2.3	DUF2341 domain-containing protein
MMP_RS05665		-0.3	-1.3	phosphate ABC transporter permease subunit PstC
MMP_RS08090		-0.3	-0.6	hypothetical protein
MMP_RS06150		-0.3	-1.4	hypothetical protein
MMP_RS00050		-0.3	-1.0	AarF/UbiB family protein
MMP_RS06460		-0.3	-0.8	pyrimidine dimer DNA glycosylase/endonuclease V
MMP_RS01805		-0.3	-1.2	NUDIX hydrolase
MMP_RS08445		-0.3	-0.6	DUF2099 family protein
MMP_RS08475		-0.3	-1.6	ABC transporter permease
MMP_RS01310		-0.3	-1.9	hypothetical protein
MMP_RS01215		-0.3	-1.3	sodium/proline symporter PutP
MMP_RS07605		-0.3	-0.5	diadenylate cyclase
MMP_RS04440		-0.3	-1.1	nitrogenase iron protein
MMP_RS00645		-0.3	-1.1	iron ABC transporter permease
MMP_RS01140		-0.3	-0.9	molybdate ABC transporter permease subunit
MMP_RS07115		-0.3	-0.9	MBL fold metallo-hydrolase
MMP_RS02300		-0.3	-1.2	NAD(P)H-dependent oxidoreductase
MMP_RS06190		-0.3	-1.0	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
MMP_RS07890		-0.3	-0.7	OB-fold nucleic acid binding domain-containing protein
MMP_RS08250		-0.3	-1.2	pyruvate kinase
MMP_RS04790		-0.3	-1.3	4-hydroxy-tetrahydrodipicolinate reductase
MMP_RS03765		-0.3	-0.7	CopG family ribbon-helix-helix protein
MMP_RS05940		-0.3	-1.3	corrinoid protein
MMP_RS05285		-0.3	-1.2	MMPL family transporter
MMP_RS08195		-0.3	-1.0	hypothetical protein
MMP_RS06095		-0.3	-1.3	ABC transporter ATP-binding protein
MMP_RS00375		-0.3	-1.3	ammonium transporter
MMP_RS06100		-0.3	-1.8	GNAT family N-acetyltransferase
MMP_RS02230		-0.3	-1.4	sodium-dependent transporter
MMP_RS07425		-0.3	-0.9	GTP-binding protein
MMP_RS03820		-0.3	-1.2	EamA family transporter
MMP_RS08460		-0.3	-0.4	proteasome-activating nucleotidase
MMP_RS02500		-0.3	-1.4	minichromosome maintenance protein MCM
MMP_RS07345		-0.3	-0.7	glycine synthesis protein GlyXL (from data)
MMP_RS04300		-0.3	-1.1	hypothetical protein
MMP_RS02245		-0.3	-0.7	hypothetical protein
MMP_RS01270		-0.3	-1.7	prepilin peptidase
MMP_RS03560		-0.2	-2.0	Na+/H+ antiporter NhaC family protein
MMP_RS01285		-0.2	-1.6	hypothetical protein
MMP_RS05895		-0.2	-1.4	metallophosphoesterase
MMP_RS05825		-0.2	-1.1	peptidyl-prolyl cis-trans isomerase

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress potassium hexahydroxoantimonate across organisms