Experiment set13S630 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete potassium hexahydroxoantimonate 0.5 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS01175 +1.9 4.6 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03300 +1.8 1.7 TOBE domain-containing protein compare
MMP_RS07735 +1.6 1.1 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS05920 +1.5 0.9 50S ribosomal protein L37e compare
MMP_RS01005 +1.5 2.2 riboflavin synthase compare
MMP_RS06625 +1.5 2.1 DNA primase compare
MMP_RS09020 +1.4 2.0 hypothetical protein compare
MMP_RS07545 +1.4 1.6 HTH domain-containing protein compare
MMP_RS01325 +1.3 2.5 dihydroneopterin aldolase family protein compare
MMP_RS01830 +1.2 1.0 tRNA-Val compare
MMP_RS06680 +1.2 7.9 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS05315 +1.1 1.8 hypothetical protein compare
MMP_RS04720 +1.1 1.7 DedA family protein compare
MMP_RS03960 +1.1 1.2 hypothetical protein compare
MMP_RS03025 +1.1 2.9 molybdenum cofactor guanylyltransferase compare
MMP_RS02345 +1.0 2.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06315 +1.0 1.3 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS01020 +1.0 1.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07385 +1.0 1.7 protein translocase SEC61 complex subunit gamma compare
MMP_RS07005 +1.0 0.6 4Fe-4S binding protein compare
MMP_RS07075 +1.0 4.0 phosphomannomutase/phosphoglucomutase compare
MMP_RS06705 +1.0 3.9 formate/nitrite transporter family protein compare
MMP_RS01955 +1.0 2.0 hypothetical protein compare
MMP_RS06885 +1.0 1.6 50S ribosome-binding GTPase compare
MMP_RS01800 +1.0 2.5 TIGR00303 family protein compare
MMP_RS06295 +0.9 3.3 methanogenesis marker 14 protein compare
MMP_RS06700 +0.9 5.1 hypothetical protein compare
MMP_RS05815 +0.9 1.5 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08720 +0.9 0.9 4Fe-4S binding protein compare
MMP_RS04605 +0.9 3.7 cobalt ECF transporter T component CbiQ compare
MMP_RS08370 +0.9 0.6 cation:proton antiporter subunit C compare
MMP_RS01600 +0.9 2.0 50S ribosomal protein L15e compare
MMP_RS02240 +0.8 2.1 methanogenesis marker 7 protein compare
MMP_RS08210 +0.8 1.9 phosphatidylglycerophosphatase A compare
MMP_RS01380 +0.8 3.5 PHP domain-containing protein compare
MMP_RS01700 +0.8 0.9 dihydroxy-acid dehydratase compare
MMP_RS01180 +0.8 2.0 XTP/dITP diphosphatase compare
MMP_RS06355 +0.8 1.1 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06685 +0.8 4.1 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS04685 +0.8 1.5 DUF126 domain-containing protein compare
MMP_RS04775 +0.8 2.0 adenosylhomocysteinase compare
MMP_RS06715 +0.8 4.6 cache domain-containing protein compare
MMP_RS01220 +0.8 3.0 hypothetical protein compare
MMP_RS01725 +0.8 2.5 class I SAM-dependent methyltransferase family protein compare
MMP_RS08745 +0.7 2.6 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS03110 +0.7 2.8 glycosyltransferase family 2 protein compare
MMP_RS07355 +0.7 0.8 transcription factor S compare
MMP_RS06020 +0.7 2.1 archaeoflavoprotein AfpA compare
MMP_RS03440 +0.7 1.0 MoaD/ThiS family protein compare
MMP_RS02110 +0.7 1.9 hypothetical protein compare
MMP_RS06350 +0.7 3.0 HesA/MoeB/ThiF family protein compare
MMP_RS02605 +0.7 0.8 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS01875 +0.7 3.6 N-acetyltransferase compare
MMP_RS06670 +0.7 1.6 glucose-6-phosphate isomerase compare
MMP_RS05515 +0.7 4.2 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS01610 +0.7 1.8 hypothetical protein compare
MMP_RS02800 +0.7 2.4 nucleotidyltransferase domain-containing protein compare
MMP_RS07635 +0.7 2.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS04615 +0.7 1.8 PDGLE domain-containing protein compare
MMP_RS08340 +0.7 1.5 4Fe-4S binding protein compare
MMP_RS01890 +0.7 1.9 nucleotide sugar dehydrogenase compare
MMP_RS07380 +0.7 1.4 transcription elongation factor Spt5 compare
MMP_RS07600 +0.6 1.2 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS07435 +0.6 1.3 GMP synthase subunit A compare
MMP_RS02805 +0.6 0.9 HEPN domain-containing protein compare
MMP_RS07680 +0.6 1.9 DUF366 family protein compare
MMP_RS01895 +0.6 3.5 flippase compare
MMP_RS01915 +0.6 3.9 DUF354 domain-containing protein compare
MMP_RS07445 +0.6 3.1 helix-turn-helix domain-containing protein compare
MMP_RS02310 +0.6 1.2 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS08435 +0.6 1.1 Era-like GTP-binding protein compare
MMP_RS00900 +0.6 1.4 50S ribosomal protein L39e compare
MMP_RS02190 +0.6 1.3 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS01265 +0.6 1.4 hypothetical protein compare
MMP_RS01650 +0.6 0.7 sulfurtransferase TusA family protein compare
MMP_RS07200 +0.6 2.2 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS04875 +0.6 1.7 energy-converting hydrogenase B subunit P compare
MMP_RS03250 +0.6 1.0 MJ1244 family protein compare
MMP_RS06340 +0.6 2.4 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06895 +0.6 0.8 selenocysteine-specific translation elongation factor compare
MMP_RS01905 +0.6 3.5 glycosyltransferase compare
MMP_RS06290 +0.6 1.9 DNA repair and recombination protein RadA compare
MMP_RS08590 +0.6 1.7 flagellin compare
MMP_RS01195 +0.6 0.8 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS03475 +0.6 0.3 hypothetical protein compare
MMP_RS00960 +0.6 2.5 iron export ABC transporter permease subunit FetB compare
MMP_RS03385 +0.6 0.6 cation diffusion facilitator family transporter compare
MMP_RS08725 +0.6 1.0 Ni/Fe hydrogenase subunit alpha compare
MMP_RS05540 +0.5 1.9 hypothetical protein compare
MMP_RS01970 +0.5 3.5 TIGR04279 domain-containing protein compare
MMP_RS05535 +0.5 1.5 hypothetical protein compare
MMP_RS06345 +0.5 2.2 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS01945 +0.5 2.7 DUF4350 domain-containing protein compare
MMP_RS07710 +0.5 2.2 cell division protein FtsZ compare
MMP_RS04780 +0.5 1.2 ribonuclease P compare
MMP_RS00665 +0.5 1.7 hypothetical protein compare
MMP_RS06285 +0.5 1.0 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS00290 +0.5 2.8 hypothetical protein compare
MMP_RS04620 +0.5 2.6 cobalt transporter CbiM compare
MMP_RS06370 +0.5 1.8 biotin synthase BioB compare
MMP_RS06865 +0.5 1.3 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS01940 +0.5 1.5 MoxR family ATPase compare
MMP_RS08280 +0.5 1.4 proteasome assembly chaperone family protein compare
MMP_RS04870 +0.5 1.2 TIGR02253 family HAD-type hydrolase compare
MMP_RS03205 +0.5 0.8 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS01910 +0.5 2.6 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS02415 +0.5 1.4 site-specific integrase compare
MMP_RS06495 +0.5 1.6 YkgJ family cysteine cluster protein compare
MMP_RS06630 +0.5 0.4 UPF0058 family protein compare
MMP_RS03400 +0.5 1.0 archease compare
MMP_RS03015 +0.5 2.5 GTP 3' 8-cyclase MoaA compare
MMP_RS06600 +0.5 0.7 class III signal peptide-containing protein compare
MMP_RS07525 +0.5 2.3 4Fe-4S binding protein compare
MMP_RS03830 +0.5 2.2 exodeoxyribonuclease VII large subunit compare
MMP_RS01925 +0.5 2.1 DUF1616 domain-containing protein compare
MMP_RS03245 +0.5 1.7 DNA repair and recombination protein RadB compare
MMP_RS03700 +0.5 1.9 sodium:proton antiporter compare
MMP_RS01795 +0.5 0.6 methanogenesis marker 6 protein compare
MMP_RS05065 +0.5 1.6 CooT family nickel-binding protein compare
MMP_RS00120 +0.5 1.8 LysR family transcriptional regulator compare
MMP_RS07350 +0.5 0.8 preprotein translocase subunit Sec61beta compare
MMP_RS01665 +0.5 1.0 DUF2111 domain-containing protein compare
MMP_RS01685 +0.5 1.0 indolepyruvate oxidoreductase subunit beta compare
MMP_RS03485 +0.5 2.0 TIGR00267 family protein compare
MMP_RS07365 +0.5 2.7 2-phosphoglycerate kinase compare
MMP_RS06760 +0.5 1.2 hypothetical protein compare
MMP_RS01885 +0.5 2.0 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS05640 +0.4 1.5 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS01775 +0.4 0.6 TIGR00297 family protein compare
MMP_RS00810 +0.4 2.1 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS03550 +0.4 0.9 DUF2124 domain-containing protein compare
MMP_RS01900 +0.4 2.9 hypothetical protein compare
MMP_RS03100 +0.4 1.1 hypothetical protein compare
MMP_RS02675 +0.4 1.5 hypothetical protein compare
MMP_RS07815 +0.4 0.6 DUF2120 domain-containing protein compare
MMP_RS01920 +0.4 2.8 glycosyltransferase family 2 protein compare
MMP_RS00830 +0.4 1.4 purine phosphoribosyltransferase family protein compare
MMP_RS06310 +0.4 1.1 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS03350 +0.4 1.5 winged helix-turn-helix domain-containing protein compare
MMP_RS01985 +0.4 1.8 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS07630 +0.4 0.6 ATP-binding cassette domain-containing protein compare
MMP_RS06490 +0.4 1.6 hypothetical protein compare
MMP_RS06555 +0.4 1.2 cupin domain-containing protein compare
MMP_RS02130 +0.4 1.7 zinc metalloprotease HtpX compare
MMP_RS01755 +0.4 0.5 DUF2097 domain-containing protein compare
MMP_RS01465 +0.4 0.8 hypothetical protein compare
MMP_RS01975 +0.4 2.8 hypothetical protein compare
MMP_RS08335 +0.4 1.4 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS02930 +0.4 1.2 class I SAM-dependent methyltransferase compare
MMP_RS05450 +0.4 1.5 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS06720 +0.4 1.8 response regulator transcription factor compare
MMP_RS02955 +0.4 1.4 DJ-1/PfpI family protein compare
MMP_RS04265 +0.4 1.0 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS03270 +0.4 1.9 ADP-ribosylglycohydrolase family protein compare
MMP_RS01950 +0.4 2.4 hypothetical protein compare
MMP_RS00565 +0.4 2.1 CBS domain-containing protein compare
MMP_RS03225 +0.4 1.8 acetolactate decarboxylase compare
MMP_RS06130 +0.4 0.9 peptidylprolyl isomerase compare
MMP_RS08715 +0.4 0.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS08595 +0.4 0.5 flagellar protein C compare
MMP_RS00520 +0.4 0.5 RNA polymerase Rpb4 family protein compare
MMP_RS03950 +0.4 2.6 HNH endonuclease compare
MMP_RS04585 +0.4 2.1 AIR synthase related protein compare
MMP_RS07705 +0.4 1.9 transcriptional regulator compare
MMP_RS02740 +0.4 1.3 hypothetical protein compare
MMP_RS07900 +0.4 0.7 YeeE/YedE family protein compare
MMP_RS03785 +0.4 1.2 cupin domain-containing protein compare
MMP_RS04955 +0.4 1.7 DNA topoisomerase I compare
MMP_RS04310 +0.4 1.6 hypothetical protein compare
MMP_RS06585 +0.4 0.7 DMT family protein compare
MMP_RS01880 +0.4 1.5 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS04315 +0.4 1.8 corrinoid protein compare
MMP_RS02265 +0.4 1.0 nitroreductase family protein compare
MMP_RS04695 +0.4 1.6 selenide water dikinase SelD compare
MMP_RS07885 +0.4 0.9 tripartite tricarboxylate transporter permease compare
MMP_RS08975 +0.4 1.1 hypothetical protein compare
MMP_RS02510 +0.4 1.7 site-specific integrase compare
MMP_RS02780 +0.4 2.5 hypothetical protein compare
MMP_RS05070 +0.4 2.2 4Fe-4S dicluster domain-containing protein compare
MMP_RS00040 +0.4 1.3 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS00965 +0.4 1.2 hypothetical protein compare
MMP_RS02790 +0.4 0.4 class III signal peptide-containing protein compare
MMP_RS06590 +0.3 1.0 GNAT family N-acetyltransferase compare
MMP_RS05035 +0.3 1.6 hypothetical protein compare
MMP_RS05145 +0.3 2.1 hypothetical protein compare
MMP_RS04650 +0.3 1.6 tetratricopeptide repeat protein compare
MMP_RS07185 +0.3 1.9 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS08310 +0.3 0.8 TMEM165/GDT1 family protein compare
MMP_RS02145 +0.3 1.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS06870 +0.3 1.8 DedA family protein compare
MMP_RS03685 +0.3 1.6 Mrp/NBP35 family ATP-binding protein compare
MMP_RS07645 +0.3 1.5 aldehyde dehydrogenase family protein compare
MMP_RS07850 +0.3 1.0 prephenate dehydratase compare
MMP_RS07180 +0.3 2.0 DEAD/DEAH box helicase compare
MMP_RS02910 +0.3 1.4 ABC transporter substrate-binding protein compare
MMP_RS01415 +0.3 1.1 DUF2067 domain-containing protein compare
MMP_RS02405 +0.3 0.8 hypothetical protein compare
MMP_RS05975 +0.3 1.6 hypothetical protein compare
MMP_RS01935 +0.3 1.8 DUF58 domain-containing protein compare
MMP_RS06550 +0.3 1.6 AMP-binding protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress potassium hexahydroxoantimonate across organisms