Experiment set13S628 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Rifampicin 0.5 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS03960 -5.3 -1.0 hypothetical protein compare
MMP_RS01225 -5.2 -5.7 DUF5379 domain-containing protein compare
MMP_RS08600 -5.1 -3.6 flagellar protein D compare
MMP_RS08460 -5.1 -3.2 proteasome-activating nucleotidase compare
MMP_RS03600 -5.1 -2.2 triose-phosphate isomerase compare
MMP_RS03435 -5.1 -2.0 ketol-acid reductoisomerase compare
MMP_RS05285 -4.9 -13.7 MMPL family transporter compare
MMP_RS05280 -4.5 -13.9 COG1361 S-layer family protein compare
MMP_RS02195 -4.4 -4.9 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS01380 -4.4 -6.5 PHP domain-containing protein compare
MMP_RS03580 -4.2 -4.0 signal recognition particle-docking protein FtsY compare
MMP_RS06110 -4.2 -3.9 ATP-dependent protease LonB compare
MMP_RS08720 -4.1 -1.6 4Fe-4S binding protein compare
MMP_RS01020 -4.1 -1.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06175 -4.1 -8.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS05290 -4.0 -14.9 TetR/AcrR family transcriptional regulator compare
MMP_RS02875 -4.0 -12.1 chorismate pyruvate-lyase family protein compare
MMP_RS07635 -3.9 -9.3 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS01005 -3.9 -1.1 riboflavin synthase compare
MMP_RS03305 -3.9 -10.7 winged helix-turn-helix domain-containing protein compare
MMP_RS09020 -3.8 -1.7 hypothetical protein compare
MMP_RS06975 -3.8 -2.5 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS03475 -3.8 -0.7 hypothetical protein compare
MMP_RS01975 -3.8 -19.8 hypothetical protein compare
MMP_RS01500 -3.8 -2.4 CBS domain-containing protein compare
MMP_RS01800 -3.8 -4.7 TIGR00303 family protein compare
MMP_RS08590 -3.8 -6.2 flagellin compare
MMP_RS07380 -3.7 -2.8 transcription elongation factor Spt5 compare
MMP_RS01495 -3.7 -11.4 TraB/GumN family protein compare
MMP_RS03445 -3.6 -1.2 methanogenesis marker 17 protein compare
MMP_RS01610 -3.6 -3.4 hypothetical protein compare
MMP_RS01755 -3.6 -1.0 DUF2097 domain-containing protein compare
MMP_RS03110 -3.6 -7.7 glycosyltransferase family 2 protein compare
MMP_RS06120 -3.6 -2.5 UPF0147 family protein compare
MMP_RS08820 -3.6 -6.7 hypothetical protein compare
MMP_RS04720 -3.5 -3.5 DedA family protein compare
MMP_RS06400 -3.5 -1.6 4Fe-4S binding protein compare
MMP_RS02280 -3.5 -1.1 DUF211 domain-containing protein compare
MMP_RS08840 -3.5 -17.8 class I SAM-dependent methyltransferase compare
MMP_RS07005 -3.5 -0.7 4Fe-4S binding protein compare
MMP_RS06895 -3.4 -1.7 selenocysteine-specific translation elongation factor compare
MMP_RS03700 -3.4 -11.0 sodium:proton antiporter compare
MMP_RS08210 -3.4 -2.3 phosphatidylglycerophosphatase A compare
MMP_RS08745 -3.4 -7.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS08595 -3.3 -1.2 flagellar protein C compare
MMP_RS07625 -3.3 -4.9 cobalt ECF transporter T component CbiQ compare
MMP_RS03315 -3.3 -1.4 ferrous iron transport protein A compare
MMP_RS04585 -3.3 -12.5 AIR synthase related protein compare
MMP_RS06035 -3.3 -13.3 glycosyltransferase family 2 protein compare
MMP_RS05635 -3.3 -9.1 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS06285 -3.3 -2.5 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS04685 -3.3 -3.7 DUF126 domain-containing protein compare
MMP_RS06700 -3.3 -12.0 hypothetical protein compare
MMP_RS08645 -3.2 -9.9 UPF0179 family protein compare
MMP_RS01325 -3.2 -2.3 dihydroneopterin aldolase family protein compare
MMP_RS02145 -3.2 -11.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS08790 -3.2 -3.1 translation initiation factor IF-2 subunit alpha compare
MMP_RS00130 -3.2 -1.6 nickel-responsive transcriptional regulator NikR compare
MMP_RS07600 -3.1 -2.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS07330 -3.1 -19.4 membrane protein compare
MMP_RS00895 -3.1 -5.1 hypothetical protein compare
MMP_RS00915 -3.1 -8.2 DUF116 domain-containing protein compare
MMP_RS04710 -3.1 -2.1 hypothetical protein compare
MMP_RS07615 -3.0 -8.6 energy-coupling factor ABC transporter permease compare
MMP_RS03205 -3.0 -1.9 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS08605 -3.0 -6.2 flagellar protein E compare
MMP_RS00515 -3.0 -1.1 DUF655 domain-containing protein compare
MMP_RS06670 -3.0 -6.8 glucose-6-phosphate isomerase compare
MMP_RS02165 -3.0 -8.6 tRNA-dihydrouridine synthase compare
MMP_RS00685 -3.0 -4.6 2-phospho-L-lactate guanylyltransferase compare
MMP_RS00735 -3.0 -6.6 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS06230 -2.9 -3.3 helix-turn-helix domain-containing protein compare
MMP_RS06475 -2.8 -5.9 FAD-dependent oxidoreductase compare
MMP_RS04780 -2.8 -3.6 ribonuclease P compare
MMP_RS05580 -2.8 -15.9 glycosyltransferase compare
MMP_RS06600 -2.8 -1.7 class III signal peptide-containing protein compare
MMP_RS06340 -2.8 -8.3 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07605 -2.8 -2.8 diadenylate cyclase compare
MMP_RS03640 -2.8 -4.1 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06295 -2.8 -5.5 methanogenesis marker 14 protein compare
MMP_RS07445 -2.7 -7.3 helix-turn-helix domain-containing protein compare
MMP_RS00730 -2.7 -7.6 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS07525 -2.7 -6.2 4Fe-4S binding protein compare
MMP_RS00315 -2.7 -8.8 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01385 -2.7 -0.7 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS07620 -2.7 -5.3 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS01365 -2.7 -3.8 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS05430 -2.7 -3.7 TIGR00288 family NYN domain-containing protein compare
MMP_RS04890 -2.6 -1.0 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS00725 -2.6 -11.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS04775 -2.6 -4.1 adenosylhomocysteinase compare
MMP_RS07200 -2.6 -7.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS01925 -2.6 -8.1 DUF1616 domain-containing protein compare
MMP_RS00520 -2.6 -1.6 RNA polymerase Rpb4 family protein compare
MMP_RS01265 -2.6 -2.6 hypothetical protein compare
MMP_RS07730 -2.6 -2.5 pyruvate synthase subunit beta compare
MMP_RS00110 -2.6 -3.4 hypothetical protein compare
MMP_RS01795 -2.5 -1.6 methanogenesis marker 6 protein compare
MMP_RS03400 -2.5 -2.7 archease compare
MMP_RS06730 -2.5 -2.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS01900 -2.5 -14.2 hypothetical protein compare
MMP_RS06725 -2.5 -8.4 hypothetical protein compare
MMP_RS08440 -2.4 -2.7 cell division protein SepF compare
MMP_RS02240 -2.4 -2.6 methanogenesis marker 7 protein compare
MMP_RS00305 -2.4 -2.0 phosphoribosyl-ATP diphosphatase compare
MMP_RS08715 -2.4 -1.8 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07875 -2.4 -4.4 hypothetical protein compare
MMP_RS07390 -2.4 -2.4 cell division protein FtsZ compare
MMP_RS06020 -2.4 -4.4 archaeoflavoprotein AfpA compare
MMP_RS07700 -2.4 -11.0 DUF1188 domain-containing protein compare
MMP_RS01970 -2.4 -14.0 TIGR04279 domain-containing protein compare
MMP_RS08650 -2.4 -3.9 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS06270 -2.4 -6.4 TIGR00300 family protein compare
MMP_RS07820 -2.4 -6.5 UPF0104 family protein compare
MMP_RS01175 -2.4 -3.3 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03535 -2.4 -3.0 helix-turn-helix transcriptional regulator compare
MMP_RS08435 -2.4 -2.4 Era-like GTP-binding protein compare
MMP_RS05640 -2.3 -7.2 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS05765 -2.3 -6.9 M42 family metallopeptidase compare
MMP_RS05930 -2.3 -2.8 3-isopropylmalate dehydratase large subunit compare
MMP_RS06680 -2.3 -9.6 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06105 -2.3 -7.7 hydrogenase maturation peptidase HycI compare
MMP_RS04870 -2.3 -5.4 TIGR02253 family HAD-type hydrolase compare
MMP_RS02900 -2.2 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS08300 -2.2 -1.4 metal-sulfur cluster assembly factor compare
MMP_RS06370 -2.2 -7.2 biotin synthase BioB compare
MMP_RS08635 -2.2 -2.1 UbiA family prenyltransferase compare
MMP_RS06625 -2.2 -1.9 DNA primase compare
MMP_RS01875 -2.2 -9.1 N-acetyltransferase compare
MMP_RS00115 -2.2 -12.1 radical SAM protein compare
MMP_RS03555 -2.2 -8.6 transcriptional regulator compare
MMP_RS08195 -2.2 -8.5 hypothetical protein compare
MMP_RS01885 -2.1 -7.8 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS03035 -2.1 -3.9 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS05345 -2.1 -6.9 hypothetical protein compare
MMP_RS07425 -2.1 -5.6 GTP-binding protein compare
MMP_RS07755 -2.1 -1.2 DUF555 domain-containing protein compare
MMP_RS06345 -2.1 -9.6 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS05550 -2.1 -0.7 cation:proton antiporter compare
MMP_RS04850 -2.1 -14.1 UPF0254 family protein compare
MMP_RS05555 -2.1 -1.7 DUF4040 domain-containing protein compare
MMP_RS00985 -2.1 -4.3 CDC48 family AAA ATPase compare
MMP_RS06315 -2.1 -0.8 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS02100 -2.1 -4.4 metallophosphoesterase compare
MMP_RS05845 -2.0 -1.6 tRNA-intron lyase compare
MMP_RS06685 -2.0 -8.3 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS01955 -2.0 -2.6 hypothetical protein compare
MMP_RS02345 -2.0 -3.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS03095 -2.0 -5.5 diphthine synthase compare
MMP_RS01985 -2.0 -4.8 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS05865 -2.0 -3.3 hypothetical protein compare
MMP_RS00300 -1.9 -0.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS07075 -1.9 -3.5 phosphomannomutase/phosphoglucomutase compare
MMP_RS04090 -1.9 -3.0 hypothetical protein compare
MMP_RS06290 -1.9 -5.8 DNA repair and recombination protein RadA compare
MMP_RS01880 -1.9 -6.5 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01865 -1.9 -1.8 GPR1/FUN34/YaaH family transporter compare
MMP_RS01960 -1.9 -1.1 hypothetical protein compare
MMP_RS06760 -1.9 -4.6 hypothetical protein compare
MMP_RS01220 -1.9 -5.5 hypothetical protein compare
MMP_RS00320 -1.9 -1.8 class I SAM-dependent methyltransferase compare
MMP_RS05295 -1.9 -8.3 minichromosome maintenance protein MCM compare
MMP_RS07420 -1.9 -2.6 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS03390 -1.9 -7.0 malate dehydrogenase compare
MMP_RS01335 -1.8 -2.4 prefoldin subunit beta compare
MMP_RS07735 -1.8 -0.7 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS08095 -1.8 -7.8 dethiobiotin synthase compare
MMP_RS03025 -1.8 -4.4 molybdenum cofactor guanylyltransferase compare
MMP_RS04500 -1.8 -11.5 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS01890 -1.8 -3.3 nucleotide sugar dehydrogenase compare
MMP_RS07545 -1.8 -0.9 HTH domain-containing protein compare
MMP_RS00850 -1.8 -4.8 TIGR01177 family methyltransferase compare
MMP_RS06395 -1.8 -4.5 ThiF family adenylyltransferase compare
MMP_RS09025 -1.8 -1.2 hypothetical protein compare
MMP_RS07685 -1.8 -7.7 TIGR01212 family radical SAM protein compare
MMP_RS05920 -1.7 -0.5 50S ribosomal protein L37e compare
MMP_RS01725 -1.7 -4.1 class I SAM-dependent methyltransferase family protein compare
MMP_RS00620 -1.7 -5.3 4Fe-4S binding protein compare
MMP_RS06940 -1.7 -2.9 polyprenyl diphosphate synthase compare
MMP_RS07695 -1.7 -6.7 DUF3236 domain-containing protein compare
MMP_RS00900 -1.6 -2.2 50S ribosomal protein L39e compare
MMP_RS07750 -1.6 -4.5 DUF357 domain-containing protein compare
MMP_RS01455 -1.6 -5.9 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS05245 -1.6 -7.9 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS06930 -1.6 -8.9 MBL fold metallo-hydrolase compare
MMP_RS05250 -1.5 -3.1 NFYB/HAP3 family transcription factor subunit compare
MMP_RS06870 -1.5 -4.6 DedA family protein compare
MMP_RS02190 -1.5 -2.5 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS07350 -1.5 -1.2 preprotein translocase subunit Sec61beta compare
MMP_RS06770 -1.5 -6.2 DHH family phosphoesterase compare
MMP_RS06840 -1.5 -1.0 DNA-directed RNA polymerase subunit N compare
MMP_RS04485 -1.5 -7.0 putative beta-lysine N-acetyltransferase compare
MMP_RS03585 -1.5 -2.4 Hsp20/alpha crystallin family protein compare
MMP_RS00695 -1.4 -0.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS08105 -1.4 -5.7 6-carboxyhexanoate--CoA ligase compare
MMP_RS07580 -1.4 -2.9 DUF356 domain-containing protein compare
MMP_RS05515 -1.4 -4.9 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS05545 -1.4 -5.0 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS00185 -1.4 -7.7 potassium channel protein compare
MMP_RS05815 -1.4 -1.8 NOL1/NOP2/sun family putative RNA methylase compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Rifampicin across organisms