Experiment set13S626 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Irgasan 0.025 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS01020 -5.1 -1.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07390 -4.6 -3.2 cell division protein FtsZ compare
MMP_RS05550 -4.1 -0.8 cation:proton antiporter compare
MMP_RS00305 -3.4 -2.6 phosphoribosyl-ATP diphosphatase compare
MMP_RS05845 -3.3 -2.3 tRNA-intron lyase compare
MMP_RS04890 -3.3 -1.0 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS05920 -3.3 -0.7 50S ribosomal protein L37e compare
MMP_RS06730 -3.2 -2.5 phosphopantothenate/pantothenate synthetase compare
MMP_RS03445 -3.1 -1.3 methanogenesis marker 17 protein compare
MMP_RS03035 -2.9 -5.4 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS03960 -2.9 -1.3 hypothetical protein compare
MMP_RS06295 -2.8 -5.5 methanogenesis marker 14 protein compare
MMP_RS02195 -2.8 -4.2 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS04585 -2.7 -10.5 AIR synthase related protein compare
MMP_RS01700 -2.7 -1.3 dihydroxy-acid dehydratase compare
MMP_RS03315 -2.7 -1.3 ferrous iron transport protein A compare
MMP_RS01795 -2.6 -1.7 methanogenesis marker 6 protein compare
MMP_RS06315 -2.6 -1.0 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS06285 -2.6 -2.6 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS06625 -2.6 -2.2 DNA primase compare
MMP_RS06685 -2.6 -11.4 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS01610 -2.6 -3.7 hypothetical protein compare
MMP_RS03600 -2.5 -2.6 triose-phosphate isomerase compare
MMP_RS07635 -2.5 -5.5 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS02280 -2.5 -1.2 DUF211 domain-containing protein compare
MMP_RS06230 -2.4 -3.3 helix-turn-helix domain-containing protein compare
MMP_RS00300 -2.4 -0.8 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06345 -2.4 -8.3 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS01755 -2.3 -1.3 DUF2097 domain-containing protein compare
MMP_RS03640 -2.3 -3.9 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06600 -2.3 -1.2 class III signal peptide-containing protein compare
MMP_RS02875 -2.3 -9.4 chorismate pyruvate-lyase family protein compare
MMP_RS00110 -2.3 -2.9 hypothetical protein compare
MMP_RS05265 -2.2 -2.9 2-isopropylmalate synthase compare
MMP_RS06680 -2.2 -7.6 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS08790 -2.2 -3.2 translation initiation factor IF-2 subunit alpha compare
MMP_RS08460 -2.2 -2.9 proteasome-activating nucleotidase compare
MMP_RS01175 -2.2 -2.9 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03475 -2.2 -0.7 hypothetical protein compare
MMP_RS08720 -2.1 -1.7 4Fe-4S binding protein compare
MMP_RS07605 -2.1 -3.6 diadenylate cyclase compare
MMP_RS07625 -2.0 -3.8 cobalt ECF transporter T component CbiQ compare
MMP_RS04780 -2.0 -3.0 ribonuclease P compare
MMP_RS07600 -2.0 -2.2 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS08210 -2.0 -2.3 phosphatidylglycerophosphatase A compare
MMP_RS01800 -2.0 -4.1 TIGR00303 family protein compare
MMP_RS07580 -2.0 -3.5 DUF356 domain-containing protein compare
MMP_RS01225 -2.0 -5.0 DUF5379 domain-containing protein compare
MMP_RS03700 -1.9 -7.1 sodium:proton antiporter compare
MMP_RS06120 -1.9 -2.8 UPF0147 family protein compare
MMP_RS08820 -1.9 -4.8 hypothetical protein compare
MMP_RS05245 -1.9 -10.4 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS08645 -1.9 -6.4 UPF0179 family protein compare
MMP_RS06340 -1.9 -6.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS01005 -1.9 -1.1 riboflavin synthase compare
MMP_RS02900 -1.8 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS07380 -1.8 -2.2 transcription elongation factor Spt5 compare
MMP_RS03555 -1.8 -7.1 transcriptional regulator compare
MMP_RS06975 -1.8 -1.9 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS03110 -1.8 -5.7 glycosyltransferase family 2 protein compare
MMP_RS03400 -1.8 -2.8 archease compare
MMP_RS05250 -1.8 -3.9 NFYB/HAP3 family transcription factor subunit compare
MMP_RS05430 -1.7 -4.8 TIGR00288 family NYN domain-containing protein compare
MMP_RS05815 -1.7 -1.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS01380 -1.7 -3.9 PHP domain-containing protein compare
MMP_RS06855 -1.7 -8.7 hypothetical protein compare
MMP_RS04870 -1.7 -3.8 TIGR02253 family HAD-type hydrolase compare
MMP_RS05280 -1.7 -9.7 COG1361 S-layer family protein compare
MMP_RS05865 -1.7 -3.2 hypothetical protein compare
MMP_RS00115 -1.6 -8.0 radical SAM protein compare
MMP_RS05875 -1.6 -4.5 hydroxyethylthiazole kinase compare
MMP_RS06840 -1.6 -1.1 DNA-directed RNA polymerase subunit N compare
MMP_RS07525 -1.6 -6.5 4Fe-4S binding protein compare
MMP_RS08715 -1.6 -1.9 formylmethanofuran dehydrogenase subunit B compare
MMP_RS00130 -1.6 -1.3 nickel-responsive transcriptional regulator NikR compare
MMP_RS03025 -1.6 -3.6 molybdenum cofactor guanylyltransferase compare
MMP_RS07445 -1.5 -5.8 helix-turn-helix domain-containing protein compare
MMP_RS07730 -1.5 -1.8 pyruvate synthase subunit beta compare
MMP_RS08300 -1.5 -1.2 metal-sulfur cluster assembly factor compare
MMP_RS04685 -1.5 -2.1 DUF126 domain-containing protein compare
MMP_RS07200 -1.5 -3.9 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS00685 -1.5 -2.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07750 -1.5 -3.9 DUF357 domain-containing protein compare
MMP_RS01250 -1.5 -6.7 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS07685 -1.5 -7.6 TIGR01212 family radical SAM protein compare
MMP_RS04710 -1.5 -1.3 hypothetical protein compare
MMP_RS07755 -1.4 -1.2 DUF555 domain-containing protein compare
MMP_RS08745 -1.4 -3.0 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06270 -1.4 -4.7 TIGR00300 family protein compare
MMP_RS03580 -1.4 -2.9 signal recognition particle-docking protein FtsY compare
MMP_RS06105 -1.4 -5.2 hydrogenase maturation peptidase HycI compare
MMP_RS06110 -1.4 -3.5 ATP-dependent protease LonB compare
MMP_RS00810 -1.4 -5.4 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS08200 -1.3 -11.5 archaeosine synthase subunit alpha compare
MMP_RS07820 -1.3 -3.1 UPF0104 family protein compare
MMP_RS07365 -1.3 -7.3 2-phosphoglycerate kinase compare
MMP_RS05545 -1.3 -3.8 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS05440 -1.3 -6.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS05765 -1.3 -3.5 M42 family metallopeptidase compare
MMP_RS03095 -1.3 -4.3 diphthine synthase compare
MMP_RS01085 -1.3 -1.9 hypothetical protein compare
MMP_RS00895 -1.3 -1.9 hypothetical protein compare
MMP_RS06400 -1.3 -0.9 4Fe-4S binding protein compare
MMP_RS07615 -1.3 -5.0 energy-coupling factor ABC transporter permease compare
MMP_RS05285 -1.3 -5.9 MMPL family transporter compare
MMP_RS07735 -1.2 -0.6 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS07425 -1.2 -4.6 GTP-binding protein compare
MMP_RS07385 -1.2 -2.3 protein translocase SEC61 complex subunit gamma compare
MMP_RS05085 -1.2 -6.9 AAA family ATPase compare
MMP_RS06475 -1.2 -4.7 FAD-dependent oxidoreductase compare
MMP_RS00320 -1.2 -1.7 class I SAM-dependent methyltransferase compare
MMP_RS07630 -1.2 -1.4 ATP-binding cassette domain-containing protein compare
MMP_RS03895 -1.2 -1.2 hypothetical protein compare
MMP_RS01500 -1.2 -1.3 CBS domain-containing protein compare
MMP_RS02165 -1.2 -5.4 tRNA-dihydrouridine synthase compare
MMP_RS09020 -1.2 -1.0 hypothetical protein compare
MMP_RS06630 -1.2 -0.6 UPF0058 family protein compare
MMP_RS08195 -1.2 -5.6 hypothetical protein compare
MMP_RS05800 -1.2 -5.1 B12-binding domain-containing radical SAM protein compare
MMP_RS07005 -1.2 -0.5 4Fe-4S binding protein compare
MMP_RS07620 -1.2 -3.6 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS05070 -1.2 -4.2 4Fe-4S dicluster domain-containing protein compare
MMP_RS05100 -1.2 -8.2 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS04775 -1.2 -2.3 adenosylhomocysteinase compare
MMP_RS07355 -1.2 -0.9 transcription factor S compare
MMP_RS05090 -1.1 -5.1 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS00515 -1.1 -0.9 DUF655 domain-containing protein compare
MMP_RS06725 -1.1 -5.1 hypothetical protein compare
MMP_RS00730 -1.1 -3.6 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS01365 -1.1 -2.1 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS01840 -1.1 -5.1 TIGR00289 family protein compare
MMP_RS05080 -1.1 -6.4 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS03020 -1.1 -3.8 peptidylprolyl isomerase compare
MMP_RS02345 -1.1 -2.7 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS07765 -1.1 -3.9 sodium:alanine symporter family protein compare
MMP_RS02190 -1.1 -2.8 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS05060 -1.1 -5.8 AAA family ATPase compare
MMP_RS06525 -1.1 -1.1 YciI family protein compare
MMP_RS00050 -1.1 -4.7 AarF/UbiB family protein compare
MMP_RS03470 -1.1 -5.2 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06355 -1.1 -1.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS07350 -1.1 -1.5 preprotein translocase subunit Sec61beta compare
MMP_RS02995 -1.0 -2.5 acyl-CoA thioesterase compare
MMP_RS02170 -1.0 -3.2 CBS domain-containing protein compare
MMP_RS00310 -1.0 -6.1 CBS domain-containing protein compare
MMP_RS00735 -1.0 -3.7 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS05075 -1.0 -6.7 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS08330 -1.0 -4.2 NADH-quinone oxidoreductase subunit H compare
MMP_RS06200 -1.0 -4.4 M24 family metallopeptidase compare
MMP_RS01725 -1.0 -2.7 class I SAM-dependent methyltransferase family protein compare
MMP_RS02235 -1.0 -5.2 CBS domain-containing protein compare
MMP_RS01220 -1.0 -3.5 hypothetical protein compare
MMP_RS01265 -1.0 -1.4 hypothetical protein compare
MMP_RS05835 -1.0 -0.7 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS02340 -1.0 -1.4 DNA-directed RNA polymerase subunit E'' compare
MMP_RS06925 -1.0 -1.6 ribonuclease VapC4 compare
MMP_RS06020 -1.0 -2.0 archaeoflavoprotein AfpA compare
MMP_RS07330 -1.0 -7.2 membrane protein compare
MMP_RS05515 -1.0 -4.6 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS02240 -1.0 -1.9 methanogenesis marker 7 protein compare
MMP_RS05925 -1.0 -2.7 small nuclear ribonucleoprotein compare
MMP_RS00315 -1.0 -2.8 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01290 -1.0 -5.0 class III signal peptide-containing protein compare
MMP_RS05055 -1.0 -5.8 DUF166 domain-containing protein compare
MMP_RS05930 -1.0 -1.6 3-isopropylmalate dehydratase large subunit compare
MMP_RS03550 -1.0 -1.2 DUF2124 domain-containing protein compare
MMP_RS01675 -1.0 -1.4 hypothetical protein compare
MMP_RS01985 -1.0 -3.2 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS08635 -0.9 -1.2 UbiA family prenyltransferase compare
MMP_RS06175 -0.9 -2.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS03210 -0.9 -6.3 tRNA guanosine(15) transglycosylase TgtA compare
MMP_RS01305 -0.9 -7.1 hypothetical protein compare
MMP_RS01720 -0.9 -1.0 replication factor C large subunit compare
MMP_RS06865 -0.9 -1.2 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS05095 -0.9 -3.2 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS00040 -0.9 -3.8 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS05290 -0.9 -4.0 TetR/AcrR family transcriptional regulator compare
MMP_RS05635 -0.9 -4.1 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS06015 -0.9 -3.3 flavodoxin family protein compare
MMP_RS01045 -0.9 -5.1 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS06350 -0.9 -2.2 HesA/MoeB/ThiF family protein compare
MMP_RS07420 -0.9 -2.6 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS03435 -0.9 -1.0 ketol-acid reductoisomerase compare
MMP_RS02100 -0.9 -2.2 metallophosphoesterase compare
MMP_RS06495 -0.8 -1.7 YkgJ family cysteine cluster protein compare
MMP_RS03305 -0.8 -4.3 winged helix-turn-helix domain-containing protein compare
MMP_RS00555 -0.8 -3.2 MFS transporter compare
MMP_RS04990 -0.8 -4.4 aquaporin family protein compare
MMP_RS00900 -0.8 -1.4 50S ribosomal protein L39e compare
MMP_RS00725 -0.8 -3.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS01285 -0.8 -5.6 hypothetical protein compare
MMP_RS01275 -0.8 -2.9 class III signal peptide-containing protein compare
MMP_RS04485 -0.8 -3.9 putative beta-lysine N-acetyltransferase compare
MMP_RS09025 -0.8 -0.8 hypothetical protein compare
MMP_RS01195 -0.8 -0.9 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS03015 -0.8 -3.7 GTP 3' 8-cyclase MoaA compare
MMP_RS07875 -0.8 -1.9 hypothetical protein compare
MMP_RS04090 -0.8 -1.0 hypothetical protein compare
MMP_RS06035 -0.8 -4.1 glycosyltransferase family 2 protein compare
MMP_RS08940 -0.8 -0.9 MetS family NSS transporter small subunit compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Irgasan across organisms