Experiment set13S625 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Anhydrotetracycline hydrochloride 0.05 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS07600 -4.4 -2.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS02900 -4.3 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS01020 -4.3 -1.2 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06895 -4.2 -1.9 selenocysteine-specific translation elongation factor compare
MMP_RS01500 -3.7 -2.7 CBS domain-containing protein compare
MMP_RS06625 -3.6 -2.6 DNA primase compare
MMP_RS07005 -3.6 -0.7 4Fe-4S binding protein compare
MMP_RS06730 -3.5 -2.9 phosphopantothenate/pantothenate synthetase compare
MMP_RS07605 -3.3 -3.8 diadenylate cyclase compare
MMP_RS02195 -3.2 -4.8 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS00515 -3.1 -1.2 DUF655 domain-containing protein compare
MMP_RS03600 -3.1 -2.9 triose-phosphate isomerase compare
MMP_RS03205 -3.1 -2.1 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS01610 -3.0 -3.0 hypothetical protein compare
MMP_RS04585 -3.0 -14.2 AIR synthase related protein compare
MMP_RS00895 -3.0 -5.0 hypothetical protein compare
MMP_RS07445 -3.0 -9.0 helix-turn-helix domain-containing protein compare
MMP_RS06975 -3.0 -3.5 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS00915 -3.0 -9.1 DUF116 domain-containing protein compare
MMP_RS08435 -2.9 -3.0 Era-like GTP-binding protein compare
MMP_RS06340 -2.9 -8.9 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS04780 -2.9 -4.2 ribonuclease P compare
MMP_RS03960 -2.9 -1.3 hypothetical protein compare
MMP_RS03435 -2.9 -2.5 ketol-acid reductoisomerase compare
MMP_RS00130 -2.9 -1.7 nickel-responsive transcriptional regulator NikR compare
MMP_RS06345 -2.9 -11.9 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS03305 -2.8 -9.6 winged helix-turn-helix domain-containing protein compare
MMP_RS01385 -2.8 -0.7 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS05265 -2.8 -3.4 2-isopropylmalate synthase compare
MMP_RS04890 -2.8 -1.0 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS04685 -2.7 -3.7 DUF126 domain-containing protein compare
MMP_RS02875 -2.7 -10.7 chorismate pyruvate-lyase family protein compare
MMP_RS06685 -2.7 -11.4 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS01325 -2.7 -2.6 dihydroneopterin aldolase family protein compare
MMP_RS00320 -2.7 -2.5 class I SAM-dependent methyltransferase compare
MMP_RS04720 -2.7 -3.2 DedA family protein compare
MMP_RS02240 -2.6 -3.3 methanogenesis marker 7 protein compare
MMP_RS02280 -2.6 -1.2 DUF211 domain-containing protein compare
MMP_RS03445 -2.6 -1.2 methanogenesis marker 17 protein compare
MMP_RS06400 -2.6 -1.6 4Fe-4S binding protein compare
MMP_RS01175 -2.6 -3.6 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS05430 -2.6 -7.1 TIGR00288 family NYN domain-containing protein compare
MMP_RS08645 -2.6 -8.8 UPF0179 family protein compare
MMP_RS07630 -2.6 -2.0 ATP-binding cassette domain-containing protein compare
MMP_RS06285 -2.5 -2.8 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS03315 -2.5 -1.3 ferrous iron transport protein A compare
MMP_RS06680 -2.5 -11.3 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS01225 -2.5 -6.7 DUF5379 domain-containing protein compare
MMP_RS00685 -2.5 -3.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS08820 -2.5 -6.1 hypothetical protein compare
MMP_RS08600 -2.5 -3.5 flagellar protein D compare
MMP_RS07635 -2.4 -7.4 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS04870 -2.4 -5.4 TIGR02253 family HAD-type hydrolase compare
MMP_RS03025 -2.4 -5.7 molybdenum cofactor guanylyltransferase compare
MMP_RS06870 -2.4 -9.2 DedA family protein compare
MMP_RS06700 -2.4 -10.6 hypothetical protein compare
MMP_RS08635 -2.4 -2.2 UbiA family prenyltransferase compare
MMP_RS06120 -2.4 -3.4 UPF0147 family protein compare
MMP_RS06175 -2.3 -6.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS06105 -2.3 -9.7 hydrogenase maturation peptidase HycI compare
MMP_RS05640 -2.3 -8.3 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS05515 -2.3 -5.5 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS07620 -2.3 -7.3 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS04710 -2.3 -2.0 hypothetical protein compare
MMP_RS07615 -2.2 -7.0 energy-coupling factor ABC transporter permease compare
MMP_RS07525 -2.2 -8.0 4Fe-4S binding protein compare
MMP_RS03640 -2.2 -3.8 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS08300 -2.2 -1.4 metal-sulfur cluster assembly factor compare
MMP_RS00115 -2.2 -12.3 radical SAM protein compare
MMP_RS06295 -2.2 -5.5 methanogenesis marker 14 protein compare
MMP_RS04775 -2.2 -3.8 adenosylhomocysteinase compare
MMP_RS02165 -2.2 -8.4 tRNA-dihydrouridine synthase compare
MMP_RS01380 -2.2 -4.5 PHP domain-containing protein compare
MMP_RS03400 -2.2 -2.3 archease compare
MMP_RS07425 -2.1 -7.7 GTP-binding protein compare
MMP_RS06885 -2.1 -3.2 50S ribosome-binding GTPase compare
MMP_RS06020 -2.1 -5.0 archaeoflavoprotein AfpA compare
MMP_RS08650 -2.1 -4.0 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS02145 -2.1 -6.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS07875 -2.1 -5.4 hypothetical protein compare
MMP_RS08595 -2.1 -1.5 flagellar protein C compare
MMP_RS00695 -2.0 -1.0 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS08790 -2.0 -2.6 translation initiation factor IF-2 subunit alpha compare
MMP_RS05865 -2.0 -4.2 hypothetical protein compare
MMP_RS05635 -2.0 -10.4 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS01985 -2.0 -5.9 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS00110 -2.0 -3.4 hypothetical protein compare
MMP_RS05245 -2.0 -9.3 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS07625 -2.0 -3.7 cobalt ECF transporter T component CbiQ compare
MMP_RS00295 -2.0 -2.5 gamma carbonic anhydrase family protein compare
MMP_RS05845 -2.0 -2.1 tRNA-intron lyase compare
MMP_RS02800 -1.9 -5.8 nucleotidyltransferase domain-containing protein compare
MMP_RS01795 -1.9 -1.5 methanogenesis marker 6 protein compare
MMP_RS06230 -1.9 -3.2 helix-turn-helix domain-containing protein compare
MMP_RS01800 -1.9 -3.7 TIGR00303 family protein compare
MMP_RS01700 -1.9 -1.1 dihydroxy-acid dehydratase compare
MMP_RS06725 -1.9 -9.1 hypothetical protein compare
MMP_RS05920 -1.9 -0.6 50S ribosomal protein L37e compare
MMP_RS03015 -1.9 -8.7 GTP 3' 8-cyclase MoaA compare
MMP_RS00900 -1.9 -2.2 50S ribosomal protein L39e compare
MMP_RS06110 -1.9 -3.9 ATP-dependent protease LonB compare
MMP_RS07420 -1.9 -3.2 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS03555 -1.8 -5.2 transcriptional regulator compare
MMP_RS06670 -1.8 -5.1 glucose-6-phosphate isomerase compare
MMP_RS00315 -1.8 -5.8 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS08720 -1.8 -1.5 4Fe-4S binding protein compare
MMP_RS08210 -1.8 -2.1 phosphatidylglycerophosphatase A compare
MMP_RS06350 -1.8 -5.5 HesA/MoeB/ThiF family protein compare
MMP_RS07575 -1.8 -4.7 RNA ligase partner protein compare
MMP_RS08590 -1.8 -5.2 flagellin compare
MMP_RS06270 -1.7 -4.1 TIGR00300 family protein compare
MMP_RS05550 -1.7 -0.7 cation:proton antiporter compare
MMP_RS06355 -1.7 -2.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS08745 -1.7 -4.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS07200 -1.7 -4.1 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS08460 -1.7 -2.2 proteasome-activating nucleotidase compare
MMP_RS05250 -1.7 -4.3 NFYB/HAP3 family transcription factor subunit compare
MMP_RS05545 -1.7 -6.2 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS07845 -1.7 -1.9 LL-diaminopimelate aminotransferase compare
MMP_RS06035 -1.7 -9.0 glycosyltransferase family 2 protein compare
MMP_RS01545 -1.7 -1.2 CBS domain-containing protein compare
MMP_RS07380 -1.6 -1.9 transcription elongation factor Spt5 compare
MMP_RS01955 -1.6 -2.3 hypothetical protein compare
MMP_RS00300 -1.6 -0.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS01005 -1.6 -1.3 riboflavin synthase compare
MMP_RS01220 -1.6 -6.1 hypothetical protein compare
MMP_RS00305 -1.6 -1.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS06930 -1.6 -9.3 MBL fold metallo-hydrolase compare
MMP_RS03580 -1.6 -3.3 signal recognition particle-docking protein FtsY compare
MMP_RS08605 -1.6 -6.4 flagellar protein E compare
MMP_RS07330 -1.6 -12.1 membrane protein compare
MMP_RS07755 -1.5 -1.2 DUF555 domain-containing protein compare
MMP_RS03035 -1.5 -4.0 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS03095 -1.5 -6.8 diphthine synthase compare
MMP_RS05295 -1.5 -6.8 minichromosome maintenance protein MCM compare
MMP_RS06855 -1.5 -7.9 hypothetical protein compare
MMP_RS00730 -1.5 -4.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS04195 -1.5 -4.1 flavodoxin compare
MMP_RS02235 -1.5 -7.0 CBS domain-containing protein compare
MMP_RS08840 -1.5 -6.7 class I SAM-dependent methyltransferase compare
MMP_RS07750 -1.5 -6.4 DUF357 domain-containing protein compare
MMP_RS07555 -1.5 -0.7 monovalent cation/H+ antiporter subunit E compare
MMP_RS07365 -1.5 -8.8 2-phosphoglycerate kinase compare
MMP_RS06290 -1.5 -4.2 DNA repair and recombination protein RadA compare
MMP_RS04875 -1.5 -4.0 energy-converting hydrogenase B subunit P compare
MMP_RS00735 -1.4 -4.3 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS01840 -1.4 -4.7 TIGR00289 family protein compare
MMP_RS00725 -1.4 -5.3 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS06865 -1.4 -1.5 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS05765 -1.4 -4.5 M42 family metallopeptidase compare
MMP_RS00985 -1.4 -3.4 CDC48 family AAA ATPase compare
MMP_RS08200 -1.4 -10.7 archaeosine synthase subunit alpha compare
MMP_RS01865 -1.4 -1.6 GPR1/FUN34/YaaH family transporter compare
MMP_RS07075 -1.4 -3.3 phosphomannomutase/phosphoglucomutase compare
MMP_RS07390 -1.4 -2.2 cell division protein FtsZ compare
MMP_RS07580 -1.3 -2.5 DUF356 domain-containing protein compare
MMP_RS07700 -1.3 -7.9 DUF1188 domain-containing protein compare
MMP_RS00290 -1.3 -5.4 hypothetical protein compare
MMP_RS05095 -1.3 -4.6 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS07730 -1.3 -1.5 pyruvate synthase subunit beta compare
MMP_RS00040 -1.3 -4.9 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS08715 -1.3 -1.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS01975 -1.3 -7.3 hypothetical protein compare
MMP_RS05580 -1.3 -7.1 glycosyltransferase compare
MMP_RS06475 -1.3 -3.4 FAD-dependent oxidoreductase compare
MMP_RS06200 -1.2 -6.5 M24 family metallopeptidase compare
MMP_RS01725 -1.2 -3.3 class I SAM-dependent methyltransferase family protein compare
MMP_RS08440 -1.2 -2.4 cell division protein SepF compare
MMP_RS01335 -1.2 -2.3 prefoldin subunit beta compare
MMP_RS06940 -1.2 -2.3 polyprenyl diphosphate synthase compare
MMP_RS01365 -1.2 -2.5 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS01755 -1.2 -0.9 DUF2097 domain-containing protein compare
MMP_RS01885 -1.2 -4.3 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01180 -1.2 -1.6 XTP/dITP diphosphatase compare
MMP_RS00810 -1.2 -4.8 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07685 -1.2 -4.0 TIGR01212 family radical SAM protein compare
MMP_RS03550 -1.1 -1.7 DUF2124 domain-containing protein compare
MMP_RS01900 -1.1 -6.3 hypothetical protein compare
MMP_RS05090 -1.1 -4.4 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS05085 -1.1 -7.3 AAA family ATPase compare
MMP_RS00185 -1.1 -7.2 potassium channel protein compare
MMP_RS03700 -1.1 -3.3 sodium:proton antiporter compare
MMP_RS05540 -1.1 -1.6 hypothetical protein compare
MMP_RS00050 -1.1 -4.2 AarF/UbiB family protein compare
MMP_RS01045 -1.1 -5.1 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS00310 -1.1 -6.8 CBS domain-containing protein compare
MMP_RS01085 -1.1 -1.6 hypothetical protein compare
MMP_RS01980 -1.1 -6.8 trimeric intracellular cation channel family protein compare
MMP_RS02340 -1.1 -1.9 DNA-directed RNA polymerase subunit E'' compare
MMP_RS05280 -1.1 -5.5 COG1361 S-layer family protein compare
MMP_RS08785 -1.1 -0.9 RNA-protein complex protein Nop10 compare
MMP_RS03590 -1.1 -4.0 METTL5 family protein compare
MMP_RS04850 -1.1 -7.2 UPF0254 family protein compare
MMP_RS01250 -1.1 -5.5 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS04485 -1.1 -5.0 putative beta-lysine N-acetyltransferase compare
MMP_RS05525 -1.1 -3.5 calcium/sodium antiporter compare
MMP_RS05800 -1.1 -5.6 B12-binding domain-containing radical SAM protein compare
MMP_RS07765 -1.0 -4.7 sodium:alanine symporter family protein compare
MMP_RS05125 -1.0 -6.8 D-aminoacyl-tRNA deacylase compare
MMP_RS02345 -1.0 -2.7 GTP-dependent dephospho-CoA kinase family protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Anhydrotetracycline hydrochloride across organisms