Experiment set13S625 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Anhydrotetracycline hydrochloride 0.05 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS01370 +2.6 12.3 acetate--CoA ligase family protein compare
MMP_RS06600 +2.0 1.7 class III signal peptide-containing protein compare
MMP_RS08350 +1.9 2.4 hypothetical protein compare
MMP_RS07415 +1.9 8.6 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS07955 +1.7 5.3 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS08340 +1.6 6.9 4Fe-4S binding protein compare
MMP_RS02885 +1.6 12.9 molybdopterin biosynthesis protein compare
MMP_RS00125 +1.3 2.2 DUF2798 domain-containing protein compare
MMP_RS03420 +1.3 6.1 acetolactate synthase small subunit compare
MMP_RS02310 +1.3 2.6 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS03215 +1.3 6.7 MBL fold metallo-hydrolase compare
MMP_RS06570 +1.3 5.4 DUF190 domain-containing protein compare
MMP_RS04695 +1.2 6.7 selenide water dikinase SelD compare
MMP_RS08275 +1.2 6.8 hypothetical protein compare
MMP_RS02790 +1.2 1.6 class III signal peptide-containing protein compare
MMP_RS08320 +1.2 4.8 molybdopterin molybdotransferase MoeA compare
MMP_RS07725 +1.1 1.8 4Fe-4S dicluster domain-containing protein compare
MMP_RS07705 +1.1 5.1 transcriptional regulator compare
MMP_RS06575 +1.1 4.8 fluoride efflux transporter CrcB compare
MMP_RS07850 +1.1 2.5 prephenate dehydratase compare
MMP_RS07125 +1.1 2.5 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS03320 +1.1 2.7 metal-dependent transcriptional regulator compare
MMP_RS00530 +1.0 3.6 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS08335 +1.0 3.9 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS05720 +0.9 2.1 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS02880 +0.9 4.9 AmmeMemoRadiSam system radical SAM enzyme compare
MMP_RS07815 +0.9 1.2 DUF2120 domain-containing protein compare
MMP_RS01525 +0.9 2.0 nucleoside-diphosphate kinase compare
MMP_RS07860 +0.9 0.7 hypothetical protein compare
MMP_RS06440 +0.9 5.3 CBS domain-containing protein compare
MMP_RS07355 +0.9 0.9 transcription factor S compare
MMP_RS04310 +0.9 2.9 hypothetical protein compare
MMP_RS00750 +0.9 1.2 fumarate hydratase compare
MMP_RS04605 +0.9 3.3 cobalt ECF transporter T component CbiQ compare
MMP_RS08315 +0.8 3.4 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS08365 +0.8 4.3 energy conserving hydrogenase EhbF compare
MMP_RS06540 +0.8 1.4 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS07890 +0.8 1.8 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS05315 +0.8 1.3 hypothetical protein compare
MMP_RS01685 +0.7 1.5 indolepyruvate oxidoreductase subunit beta compare
MMP_RS04620 +0.7 4.0 cobalt transporter CbiM compare
MMP_RS07970 +0.7 2.5 hypothetical protein compare
MMP_RS05365 +0.7 2.0 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS02405 +0.7 1.7 hypothetical protein compare
MMP_RS08360 +0.7 3.5 hypothetical protein compare
MMP_RS06590 +0.7 1.8 GNAT family N-acetyltransferase compare
MMP_RS08415 +0.7 2.3 radical SAM protein compare
MMP_RS07960 +0.7 3.5 sugar phosphate isomerase/epimerase compare
MMP_RS08345 +0.7 3.7 4Fe-4S binding protein compare
MMP_RS04055 +0.7 1.1 hypothetical protein compare
MMP_RS08215 +0.7 2.5 DUF483 domain-containing protein compare
MMP_RS08355 +0.6 2.9 Na(+)/H(+) antiporter subunit B compare
MMP_RS08265 +0.6 2.2 rubrerythrin compare
MMP_RS00450 +0.6 1.1 4Fe-4S binding protein compare
MMP_RS08995 +0.6 0.9 hypothetical protein compare
MMP_RS05460 +0.6 3.7 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS02480 +0.6 1.5 hypothetical protein compare
MMP_RS02045 +0.6 1.0 tRNA-Met compare
MMP_RS01775 +0.6 1.2 TIGR00297 family protein compare
MMP_RS06910 +0.6 3.4 RlmF-related methyltransferase compare
MMP_RS01605 +0.6 3.2 hypothetical protein compare
MMP_RS05685 +0.6 2.6 winged helix-turn-helix domain-containing protein compare
MMP_RS07560 +0.5 3.2 prefoldin subunit alpha compare
MMP_RS07130 +0.5 3.1 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS03485 +0.5 1.6 TIGR00267 family protein compare
MMP_RS05985 +0.5 1.5 hypothetical protein compare
MMP_RS00945 +0.5 0.7 PadR family transcriptional regulator compare
MMP_RS03465 +0.5 0.7 adenine phosphoribosyltransferase compare
MMP_RS07115 +0.5 1.4 MBL fold metallo-hydrolase compare
MMP_RS06170 +0.5 2.5 ABC transporter ATP-binding protein compare
MMP_RS02300 +0.5 2.1 NAD(P)H-dependent oxidoreductase compare
MMP_RS02805 +0.5 0.6 HEPN domain-containing protein compare
MMP_RS08175 +0.5 2.0 7-cyano-7-deazaguanine synthase compare
MMP_RS06165 +0.5 2.2 ABC transporter permease compare
MMP_RS05950 +0.5 2.1 nickel-dependent hydrogenase large subunit compare
MMP_RS01660 +0.5 1.1 hypothetical protein compare
MMP_RS07145 +0.5 2.4 AmmeMemoRadiSam system protein B compare
MMP_RS06485 +0.5 0.4 zinc ribbon domain-containing protein compare
MMP_RS07910 +0.5 2.2 NAD(P)H-hydrate dehydratase compare
MMP_RS03675 +0.5 2.8 RimK family alpha-L-glutamate ligase compare
MMP_RS08775 +0.5 1.9 methanogenesis marker 9 domain-containing protein compare
MMP_RS01105 +0.5 2.2 hypothetical protein compare
MMP_RS01540 +0.5 1.1 DUF504 domain-containing protein compare
MMP_RS06610 +0.5 1.7 DUF2334 domain-containing protein compare
MMP_RS00760 +0.5 2.5 branched-chain-amino-acid transaminase compare
MMP_RS03895 +0.4 1.4 hypothetical protein compare
MMP_RS07840 +0.4 1.2 ribonuclease III compare
MMP_RS06075 +0.4 2.4 class I SAM-dependent methyltransferase compare
MMP_RS07150 +0.4 1.4 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS00770 +0.4 1.4 hypothetical protein compare
MMP_RS00480 +0.4 2.7 hypothetical protein compare
MMP_RS06860 +0.4 0.6 4Fe-4S binding protein compare
MMP_RS01255 +0.4 1.5 amino acid ABC transporter ATP-binding protein compare
MMP_RS03495 +0.4 1.3 Na/Pi cotransporter family protein compare
MMP_RS03115 +0.4 2.7 hypothetical protein compare
MMP_RS00975 +0.4 2.3 HD domain-containing protein compare
MMP_RS07915 +0.4 1.5 DUF4870 domain-containing protein compare
MMP_RS01150 +0.4 1.7 aldo/keto reductase compare
MMP_RS05415 +0.4 1.5 DUF22 domain-containing protein compare
MMP_RS08370 +0.4 0.3 cation:proton antiporter subunit C compare
MMP_RS02415 +0.4 0.8 site-specific integrase compare
MMP_RS01320 +0.4 2.3 hypothetical protein compare
MMP_RS08380 +0.4 2.1 phosphatase PAP2 family protein compare
MMP_RS06705 +0.4 1.3 formate/nitrite transporter family protein compare
MMP_RS02595 +0.4 0.5 putative zinc-binding protein compare
MMP_RS06500 +0.4 2.3 ATP-binding protein compare
MMP_RS08395 +0.4 1.3 DsrE family protein compare
MMP_RS07335 +0.4 1.3 tRNA (cytidine(56)-2'-O)-methyltransferase compare
MMP_RS06150 +0.4 2.8 hypothetical protein compare
MMP_RS00660 +0.4 2.3 alkaline phosphatase family protein compare
MMP_RS01130 +0.4 2.4 flavoprotein compare
MMP_RS00665 +0.4 1.0 hypothetical protein compare
MMP_RS06335 +0.4 1.7 HAD family hydrolase compare
MMP_RS05965 +0.4 1.3 carboxymuconolactone decarboxylase family protein compare
MMP_RS03965 +0.4 0.9 hypothetical protein compare
MMP_RS02755 +0.4 1.7 ABC transporter permease compare
MMP_RS01430 +0.4 1.9 mechanosensitive ion channel family protein compare
MMP_RS01165 +0.4 1.5 DUF434 domain-containing protein compare
MMP_RS01435 +0.4 1.2 DMT family transporter compare
MMP_RS05945 +0.4 0.9 CBS domain-containing protein compare
MMP_RS02960 +0.4 2.2 class I SAM-dependent methyltransferase family protein compare
MMP_RS02470 +0.4 0.4 helix-turn-helix transcriptional regulator compare
MMP_RS02510 +0.4 2.1 site-specific integrase compare
MMP_RS00565 +0.4 1.2 CBS domain-containing protein compare
MMP_RS06000 +0.4 1.7 divalent-cation tolerance protein CutA compare
MMP_RS04105 +0.4 1.7 MarR family transcriptional regulator compare
MMP_RS09035 +0.4 1.4 hypothetical protein compare
MMP_RS06060 +0.3 2.0 hypothetical protein compare
MMP_RS01155 +0.3 1.3 XRE family transcriptional regulator compare
MMP_RS07095 +0.3 1.0 PspC domain-containing protein compare
MMP_RS07120 +0.3 2.4 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS06515 +0.3 1.0 UPF0489 family protein compare
MMP_RS00990 +0.3 1.2 hypothetical protein compare
MMP_RS07855 +0.3 1.6 class I SAM-dependent methyltransferase compare
MMP_RS08250 +0.3 1.5 pyruvate kinase compare
MMP_RS06550 +0.3 1.2 AMP-binding protein compare
MMP_RS08410 +0.3 1.3 DUF169 domain-containing protein compare
MMP_RS07650 +0.3 1.9 TldD/PmbA family protein compare
MMP_RS03735 +0.3 1.8 indolepyruvate ferredoxin oxidoreductase subunit alpha compare
MMP_RS00630 +0.3 1.3 ECF transporter S component compare
MMP_RS05450 +0.3 1.0 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS03010 +0.3 2.2 cupin domain-containing protein compare
MMP_RS07190 +0.3 1.2 chromosome segregation protein SMC compare
MMP_RS05955 +0.3 0.7 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS07135 +0.3 1.5 coenzyme F420 hydrogenase subunit beta compare
MMP_RS06535 +0.3 0.8 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS04475 +0.3 1.7 nitrogen fixation compare
MMP_RS00325 +0.3 0.6 RNA-binding protein compare
MMP_RS08850 +0.3 2.3 hypothetical protein compare
MMP_RS06130 +0.3 0.5 peptidylprolyl isomerase compare
MMP_RS00105 +0.3 1.6 hypothetical protein compare
MMP_RS08930 +0.3 0.6 hypothetical protein compare
MMP_RS01145 +0.3 1.4 ABC transporter ATP-binding protein compare
MMP_RS03765 +0.3 1.2 CopG family ribbon-helix-helix protein compare
MMP_RS05980 +0.3 1.1 ferritin compare
MMP_RS04520 +0.3 0.9 nucleoside deaminase compare
MMP_RS06480 +0.3 1.2 ABC transporter substrate-binding protein compare
MMP_RS08245 +0.3 1.4 DUF4013 domain-containing protein compare
MMP_RS07545 +0.3 0.3 HTH domain-containing protein compare
MMP_RS00120 +0.3 1.0 LysR family transcriptional regulator compare
MMP_RS05675 +0.3 0.5 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS00740 +0.3 0.5 cyclase family protein compare
MMP_RS04960 +0.3 2.0 cytochrome c biogenesis CcdA family protein compare
MMP_RS07570 +0.3 1.6 nucleotidyltransferase family protein compare
MMP_RS09030 +0.3 1.0 hypothetical protein compare
MMP_RS01470 +0.3 0.7 ATP-binding cassette domain-containing protein compare
MMP_RS02390 +0.3 1.3 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS03840 +0.3 1.1 hypothetical protein compare
MMP_RS01060 +0.3 2.0 calcium/sodium antiporter compare
MMP_RS00235 +0.3 1.3 HDIG domain-containing protein compare
MMP_RS00705 +0.3 0.6 hypothetical protein compare
MMP_RS08665 +0.3 2.0 hypothetical protein compare
MMP_RS00155 +0.3 1.4 heavy metal-binding domain-containing protein compare
MMP_RS03280 +0.3 1.0 pyridoxamine 5'-phosphate oxidase family protein compare
MMP_RS01115 +0.3 1.7 molybdopterin molybdotransferase MoeA compare
MMP_RS03790 +0.3 1.2 hypothetical protein compare
MMP_RS06745 +0.3 0.5 DUF2119 domain-containing protein compare
MMP_RS06555 +0.3 0.6 cupin domain-containing protein compare
MMP_RS02895 +0.3 1.4 DHH family phosphoesterase compare
MMP_RS00800 +0.3 1.5 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06385 +0.3 1.0 hypothetical protein compare
MMP_RS07085 +0.3 1.6 ribonuclease HII compare
MMP_RS03670 +0.3 0.7 DUF1890 domain-containing protein compare
MMP_RS00670 +0.3 0.7 TIM barrel protein compare
MMP_RS01620 +0.3 0.9 hypothetical protein compare
MMP_RS05595 +0.3 1.7 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS00100 +0.2 1.4 tRNA pseudouridine(13) synthase TruD compare
MMP_RS02360 +0.2 1.3 hypothetical protein compare
MMP_RS01485 +0.2 1.6 right-handed parallel beta-helix repeat-containing protein compare
MMP_RS02650 +0.2 1.0 flavodoxin family protein compare
MMP_RS02555 +0.2 2.1 AIPR family protein compare
MMP_RS02645 +0.2 1.1 ArsR family transcriptional regulator compare
MMP_RS02465 +0.2 1.3 hypothetical protein compare
MMP_RS07590 +0.2 1.5 hypothetical protein compare
MMP_RS05660 +0.2 1.3 phosphate ABC transporter substrate-binding protein compare
MMP_RS02780 +0.2 1.6 hypothetical protein compare
MMP_RS02290 +0.2 0.9 MBL fold metallo-hydrolase compare
MMP_RS02770 +0.2 1.3 hypothetical protein compare
MMP_RS08845 +0.2 1.4 archaellum operon transcriptional activator EarA family protein compare
MMP_RS04205 +0.2 0.8 carboxymuconolactone decarboxylase family protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Anhydrotetracycline hydrochloride across organisms