Experiment set13S619 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Sodium hypophosphite monohydrate 125 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS01500 -5.8 -1.5 CBS domain-containing protein compare
MMP_RS00520 -5.6 -1.4 RNA polymerase Rpb4 family protein compare
MMP_RS05550 -3.7 -0.5 cation:proton antiporter compare
MMP_RS00300 -3.6 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS01265 -3.6 -2.4 hypothetical protein compare
MMP_RS01385 -3.4 -0.5 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01755 -3.3 -0.7 DUF2097 domain-containing protein compare
MMP_RS07005 -3.2 -0.5 4Fe-4S binding protein compare
MMP_RS03600 -3.0 -1.8 triose-phosphate isomerase compare
MMP_RS08300 -3.0 -0.7 metal-sulfur cluster assembly factor compare
MMP_RS00695 -2.9 -0.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS08595 -2.8 -1.0 flagellar protein C compare
MMP_RS07600 -2.8 -1.5 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS03205 -2.8 -1.2 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS02175 -2.7 -0.8 DUF1611 domain-containing protein compare
MMP_RS00110 -2.6 -2.0 hypothetical protein compare
MMP_RS06285 -2.6 -1.3 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS03960 -2.5 -0.8 hypothetical protein compare
MMP_RS03440 -2.3 -1.1 MoaD/ThiS family protein compare
MMP_RS08440 -2.3 -2.3 cell division protein SepF compare
MMP_RS08460 -2.3 -1.8 proteasome-activating nucleotidase compare
MMP_RS07635 -2.1 -4.0 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08645 -2.0 -4.6 UPF0179 family protein compare
MMP_RS01960 -2.0 -0.7 hypothetical protein compare
MMP_RS02145 -1.9 -5.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS04585 -1.9 -6.2 AIR synthase related protein compare
MMP_RS07385 -1.9 -2.3 protein translocase SEC61 complex subunit gamma compare
MMP_RS00305 -1.9 -1.2 phosphoribosyl-ATP diphosphatase compare
MMP_RS05515 -1.9 -4.2 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS05865 -1.9 -1.8 hypothetical protein compare
MMP_RS03550 -1.9 -1.7 DUF2124 domain-containing protein compare
MMP_RS01545 -1.8 -0.8 CBS domain-containing protein compare
MMP_RS01325 -1.8 -1.3 dihydroneopterin aldolase family protein compare
MMP_RS08615 -1.7 -1.8 flagellar protein G compare
MMP_RS01610 -1.6 -1.6 hypothetical protein compare
MMP_RS08635 -1.6 -1.3 UbiA family prenyltransferase compare
MMP_RS06350 -1.6 -2.3 HesA/MoeB/ThiF family protein compare
MMP_RS08790 -1.6 -1.6 translation initiation factor IF-2 subunit alpha compare
MMP_RS06485 -1.6 -0.6 zinc ribbon domain-containing protein compare
MMP_RS03700 -1.6 -5.4 sodium:proton antiporter compare
MMP_RS00900 -1.6 -1.0 50S ribosomal protein L39e compare
MMP_RS08210 -1.5 -1.4 phosphatidylglycerophosphatase A compare
MMP_RS04780 -1.5 -1.9 ribonuclease P compare
MMP_RS06120 -1.5 -1.3 UPF0147 family protein compare
MMP_RS01335 -1.5 -1.8 prefoldin subunit beta compare
MMP_RS04685 -1.4 -1.6 DUF126 domain-containing protein compare
MMP_RS05835 -1.4 -0.6 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS00850 -1.4 -2.7 TIGR01177 family methyltransferase compare
MMP_RS01005 -1.4 -0.6 riboflavin synthase compare
MMP_RS04775 -1.4 -2.0 adenosylhomocysteinase compare
MMP_RS03315 -1.4 -0.6 ferrous iron transport protein A compare
MMP_RS01380 -1.4 -2.3 PHP domain-containing protein compare
MMP_RS02495 -1.4 -1.8 hypothetical protein compare
MMP_RS03445 -1.4 -0.6 methanogenesis marker 17 protein compare
MMP_RS07605 -1.3 -1.6 diadenylate cyclase compare
MMP_RS06015 -1.3 -4.5 flavodoxin family protein compare
MMP_RS06230 -1.3 -1.4 helix-turn-helix domain-containing protein compare
MMP_RS01225 -1.3 -2.5 DUF5379 domain-containing protein compare
MMP_RS06355 -1.3 -1.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS04035 -1.2 -1.5 hypothetical protein compare
MMP_RS00685 -1.2 -2.0 2-phospho-L-lactate guanylyltransferase compare
MMP_RS06020 -1.2 -1.9 archaeoflavoprotein AfpA compare
MMP_RS01020 -1.2 -0.5 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS00295 -1.2 -1.1 gamma carbonic anhydrase family protein compare
MMP_RS03035 -1.2 -2.0 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS05765 -1.2 -3.2 M42 family metallopeptidase compare
MMP_RS06600 -1.2 -0.8 class III signal peptide-containing protein compare
MMP_RS02345 -1.2 -1.9 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS00895 -1.2 -1.9 hypothetical protein compare
MMP_RS02875 -1.2 -4.4 chorismate pyruvate-lyase family protein compare
MMP_RS05430 -1.2 -3.7 TIGR00288 family NYN domain-containing protein compare
MMP_RS02280 -1.2 -0.5 DUF211 domain-containing protein compare
MMP_RS07425 -1.2 -2.8 GTP-binding protein compare
MMP_RS00130 -1.1 -0.7 nickel-responsive transcriptional regulator NikR compare
MMP_RS06725 -1.1 -4.0 hypothetical protein compare
MMP_RS08860 -1.1 -2.6 MinD/ParA family protein compare
MMP_RS03555 -1.1 -3.0 transcriptional regulator compare
MMP_RS01285 -1.1 -5.6 hypothetical protein compare
MMP_RS07845 -1.1 -0.7 LL-diaminopimelate aminotransferase compare
MMP_RS02170 -1.1 -2.8 CBS domain-containing protein compare
MMP_RS05245 -1.1 -5.2 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS02165 -1.1 -3.9 tRNA-dihydrouridine synthase compare
MMP_RS01085 -1.1 -1.0 hypothetical protein compare
MMP_RS07525 -1.1 -3.9 4Fe-4S binding protein compare
MMP_RS07755 -1.1 -0.7 DUF555 domain-containing protein compare
MMP_RS06345 -1.1 -3.7 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS02605 -1.1 -0.5 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS01655 -1.0 -1.9 DsrE family protein compare
MMP_RS04485 -1.0 -4.6 putative beta-lysine N-acetyltransferase compare
MMP_RS07390 -1.0 -1.1 cell division protein FtsZ compare
MMP_RS07380 -1.0 -0.8 transcription elongation factor Spt5 compare
MMP_RS02240 -1.0 -1.2 methanogenesis marker 7 protein compare
MMP_RS00115 -1.0 -5.1 radical SAM protein compare
MMP_RS00315 -1.0 -2.0 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS06130 -1.0 -1.9 peptidylprolyl isomerase compare
MMP_RS02940 -1.0 -1.9 TatD family hydrolase compare
MMP_RS05545 -1.0 -2.6 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS06400 -1.0 -0.5 4Fe-4S binding protein compare
MMP_RS03025 -1.0 -2.1 molybdenum cofactor guanylyltransferase compare
MMP_RS04420 -1.0 -2.5 LysE family translocator compare
MMP_RS06310 -0.9 -2.3 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS02235 -0.9 -2.5 CBS domain-containing protein compare
MMP_RS07620 -0.9 -1.8 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS06430 -0.9 -2.2 6-carboxytetrahydropterin synthase QueD compare
MMP_RS05355 -0.9 -0.5 hypothetical protein compare
MMP_RS00620 -0.9 -3.4 4Fe-4S binding protein compare
MMP_RS06340 -0.9 -3.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00710 -0.9 -1.5 hypothetical protein compare
MMP_RS04475 -0.9 -1.6 nitrogen fixation compare
MMP_RS04870 -0.9 -1.9 TIGR02253 family HAD-type hydrolase compare
MMP_RS06200 -0.9 -4.0 M24 family metallopeptidase compare
MMP_RS03015 -0.9 -2.9 GTP 3' 8-cyclase MoaA compare
MMP_RS01075 -0.9 -0.8 hypothetical protein compare
MMP_RS06295 -0.9 -2.1 methanogenesis marker 14 protein compare
MMP_RS03520 -0.9 -1.0 YwbE family protein compare
MMP_RS00810 -0.9 -2.6 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS02675 -0.9 -0.7 hypothetical protein compare
MMP_RS07445 -0.9 -2.9 helix-turn-helix domain-containing protein compare
MMP_RS06175 -0.9 -2.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS03390 -0.9 -2.0 malate dehydrogenase compare
MMP_RS08310 -0.9 -1.0 TMEM165/GDT1 family protein compare
MMP_RS06885 -0.9 -0.7 50S ribosome-binding GTPase compare
MMP_RS06475 -0.9 -1.9 FAD-dependent oxidoreductase compare
MMP_RS01275 -0.9 -3.0 class III signal peptide-containing protein compare
MMP_RS04060 -0.9 -1.9 hypothetical protein compare
MMP_RS00735 -0.9 -2.3 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS06625 -0.9 -0.7 DNA primase compare
MMP_RS01790 -0.8 -3.4 restriction endonuclease compare
MMP_RS05635 -0.8 -2.8 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS03125 -0.8 -1.8 cell division ATPase MinD compare
MMP_RS08600 -0.8 -0.8 flagellar protein D compare
MMP_RS00725 -0.8 -4.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS07700 -0.8 -3.7 DUF1188 domain-containing protein compare
MMP_RS03875 -0.8 -1.7 hypothetical protein compare
MMP_RS04985 -0.8 -1.8 DUF2180 family protein compare
MMP_RS03580 -0.8 -1.0 signal recognition particle-docking protein FtsY compare
MMP_RS04125 -0.8 -1.5 TetR/AcrR family transcriptional regulator compare
MMP_RS08785 -0.8 -0.5 RNA-protein complex protein Nop10 compare
MMP_RS06940 -0.8 -1.5 polyprenyl diphosphate synthase compare
MMP_RS03385 -0.8 -0.4 cation diffusion facilitator family transporter compare
MMP_RS07695 -0.8 -2.7 DUF3236 domain-containing protein compare
MMP_RS06395 -0.8 -2.0 ThiF family adenylyltransferase compare
MMP_RS03680 -0.8 -3.0 hypothetical protein compare
MMP_RS08750 -0.8 -0.6 hypothetical protein compare
MMP_RS03020 -0.8 -2.8 peptidylprolyl isomerase compare
MMP_RS06685 -0.8 -3.0 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08675 -0.8 -1.5 class III signal peptide-containing protein compare
MMP_RS04305 -0.8 -0.7 hypothetical protein compare
MMP_RS08720 -0.8 -0.5 4Fe-4S binding protein compare
MMP_RS02490 -0.8 -1.2 hypothetical protein compare
MMP_RS08195 -0.8 -3.2 hypothetical protein compare
MMP_RS01980 -0.8 -3.6 trimeric intracellular cation channel family protein compare
MMP_RS03585 -0.8 -1.4 Hsp20/alpha crystallin family protein compare
MMP_RS07685 -0.8 -2.2 TIGR01212 family radical SAM protein compare
MMP_RS05250 -0.8 -1.1 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08820 -0.8 -2.1 hypothetical protein compare
MMP_RS01570 -0.8 -0.7 hypothetical protein compare
MMP_RS01175 -0.8 -0.8 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08715 -0.8 -0.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS00385 -0.8 -1.6 P-II family nitrogen regulator compare
MMP_RS07575 -0.8 -1.6 RNA ligase partner protein compare
MMP_RS04850 -0.8 -4.8 UPF0254 family protein compare
MMP_RS06975 -0.8 -1.1 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS02195 -0.7 -1.0 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS05900 -0.7 -1.8 tetratricopeptide repeat protein compare
MMP_RS07365 -0.7 -3.5 2-phosphoglycerate kinase compare
MMP_RS03140 -0.7 -2.5 hypothetical protein compare
MMP_RS00245 -0.7 -5.3 type II secretion system F family protein compare
MMP_RS01665 -0.7 -1.6 DUF2111 domain-containing protein compare
MMP_RS03465 -0.7 -0.6 adenine phosphoribosyltransferase compare
MMP_RS08930 -0.7 -0.7 hypothetical protein compare
MMP_RS01575 -0.7 -2.7 aldolase compare
MMP_RS05510 -0.7 -2.1 Rrf2 family transcriptional regulator compare
MMP_RS04795 -0.7 -2.1 tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY compare
MMP_RS07765 -0.7 -2.6 sodium:alanine symporter family protein compare
MMP_RS06900 -0.7 -1.1 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS00320 -0.7 -0.6 class I SAM-dependent methyltransferase compare
MMP_RS05540 -0.7 -1.4 hypothetical protein compare
MMP_RS02700 -0.7 -2.4 formylmethanofuran dehydrogenase subunit C compare
MMP_RS06270 -0.7 -1.9 TIGR00300 family protein compare
MMP_RS05875 -0.7 -1.2 hydroxyethylthiazole kinase compare
MMP_RS07880 -0.7 -2.7 AAA family ATPase compare
MMP_RS06585 -0.7 -0.6 DMT family protein compare
MMP_RS07535 -0.7 -2.5 4Fe-4S binding protein compare
MMP_RS01030 -0.7 -2.2 MTAP family purine nucleoside phosphorylase compare
MMP_RS08855 -0.7 -3.1 hypothetical protein compare
MMP_RS00310 -0.7 -2.6 CBS domain-containing protein compare
MMP_RS08200 -0.7 -4.5 archaeosine synthase subunit alpha compare
MMP_RS08555 -0.7 -0.9 hypothetical protein compare
MMP_RS03535 -0.7 -1.1 helix-turn-helix transcriptional regulator compare
MMP_RS03405 -0.7 -2.1 RNA 3'-terminal phosphate cyclase compare
MMP_RS08385 -0.7 -2.4 ABC transporter substrate-binding protein compare
MMP_RS06590 -0.7 -0.9 GNAT family N-acetyltransferase compare
MMP_RS04980 -0.7 -3.2 DUF2193 domain-containing protein compare
MMP_RS01440 -0.7 -1.3 NAAT family transporter compare
MMP_RS08650 -0.6 -0.8 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01280 -0.6 -3.5 DUF515 domain-containing protein compare
MMP_RS04945 -0.6 -1.2 hypothetical protein compare
MMP_RS04480 -0.6 -3.5 lysine 2 3-aminomutase compare
MMP_RS02815 -0.6 -1.0 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium hypophosphite monohydrate across organisms