Experiment set13S616 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Polymyxin B sulfate 0.1 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS08460 -5.5 -2.5 proteasome-activating nucleotidase compare
MMP_RS01380 -4.4 -6.4 PHP domain-containing protein compare
MMP_RS03960 -4.2 -1.1 hypothetical protein compare
MMP_RS06730 -4.1 -2.6 phosphopantothenate/pantothenate synthetase compare
MMP_RS02900 -4.1 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS08820 -4.1 -6.1 hypothetical protein compare
MMP_RS01500 -3.9 -2.5 CBS domain-containing protein compare
MMP_RS00300 -3.8 -0.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06700 -3.8 -12.0 hypothetical protein compare
MMP_RS01610 -3.7 -3.3 hypothetical protein compare
MMP_RS00915 -3.6 -7.8 DUF116 domain-containing protein compare
MMP_RS07635 -3.5 -9.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06110 -3.5 -4.2 ATP-dependent protease LonB compare
MMP_RS07005 -3.4 -0.6 4Fe-4S binding protein compare
MMP_RS06400 -3.4 -1.5 4Fe-4S binding protein compare
MMP_RS01020 -3.4 -1.0 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS00305 -3.3 -2.3 phosphoribosyl-ATP diphosphatase compare
MMP_RS06350 -3.3 -8.1 HesA/MoeB/ThiF family protein compare
MMP_RS06355 -3.3 -2.8 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06975 -3.3 -3.2 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07380 -3.2 -2.7 transcription elongation factor Spt5 compare
MMP_RS03600 -3.2 -2.5 triose-phosphate isomerase compare
MMP_RS06475 -3.2 -6.0 FAD-dependent oxidoreductase compare
MMP_RS08435 -3.2 -2.6 Era-like GTP-binding protein compare
MMP_RS08720 -3.2 -1.6 4Fe-4S binding protein compare
MMP_RS05845 -3.2 -2.2 tRNA-intron lyase compare
MMP_RS01225 -3.1 -5.6 DUF5379 domain-containing protein compare
MMP_RS05515 -3.1 -5.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06625 -3.0 -1.8 DNA primase compare
MMP_RS05550 -3.0 -0.8 cation:proton antiporter compare
MMP_RS04585 -3.0 -11.0 AIR synthase related protein compare
MMP_RS00130 -3.0 -1.4 nickel-responsive transcriptional regulator NikR compare
MMP_RS06285 -2.9 -2.2 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS00115 -2.9 -14.2 radical SAM protein compare
MMP_RS03015 -2.8 -10.0 GTP 3' 8-cyclase MoaA compare
MMP_RS08635 -2.8 -2.1 UbiA family prenyltransferase compare
MMP_RS07445 -2.8 -6.4 helix-turn-helix domain-containing protein compare
MMP_RS01175 -2.8 -3.6 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08790 -2.8 -2.4 translation initiation factor IF-2 subunit alpha compare
MMP_RS07390 -2.7 -2.5 cell division protein FtsZ compare
MMP_RS03475 -2.7 -0.7 hypothetical protein compare
MMP_RS06680 -2.7 -10.3 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03025 -2.7 -6.0 molybdenum cofactor guanylyltransferase compare
MMP_RS03315 -2.7 -1.1 ferrous iron transport protein A compare
MMP_RS03400 -2.6 -3.0 archease compare
MMP_RS04780 -2.6 -3.6 ribonuclease P compare
MMP_RS06230 -2.6 -3.2 helix-turn-helix domain-containing protein compare
MMP_RS06685 -2.6 -9.4 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS06870 -2.5 -7.2 DedA family protein compare
MMP_RS01755 -2.5 -1.1 DUF2097 domain-containing protein compare
MMP_RS03445 -2.5 -1.1 methanogenesis marker 17 protein compare
MMP_RS08645 -2.5 -9.1 UPF0179 family protein compare
MMP_RS02875 -2.5 -11.7 chorismate pyruvate-lyase family protein compare
MMP_RS08650 -2.5 -3.4 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS06175 -2.5 -6.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS06020 -2.5 -4.8 archaeoflavoprotein AfpA compare
MMP_RS00895 -2.4 -5.0 hypothetical protein compare
MMP_RS07755 -2.4 -1.3 DUF555 domain-containing protein compare
MMP_RS00515 -2.4 -1.0 DUF655 domain-containing protein compare
MMP_RS06345 -2.4 -11.3 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS00695 -2.4 -0.8 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS04890 -2.4 -1.0 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS03435 -2.4 -1.9 ketol-acid reductoisomerase compare
MMP_RS07525 -2.3 -8.1 4Fe-4S binding protein compare
MMP_RS02165 -2.3 -8.6 tRNA-dihydrouridine synthase compare
MMP_RS07600 -2.3 -1.8 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS04685 -2.3 -3.1 DUF126 domain-containing protein compare
MMP_RS06340 -2.3 -8.1 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07735 -2.3 -0.6 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS01800 -2.3 -3.1 TIGR00303 family protein compare
MMP_RS05430 -2.3 -2.8 TIGR00288 family NYN domain-containing protein compare
MMP_RS04870 -2.3 -4.6 TIGR02253 family HAD-type hydrolase compare
MMP_RS01545 -2.3 -1.2 CBS domain-containing protein compare
MMP_RS06270 -2.2 -6.2 TIGR00300 family protein compare
MMP_RS07625 -2.2 -3.2 cobalt ECF transporter T component CbiQ compare
MMP_RS03580 -2.2 -3.4 signal recognition particle-docking protein FtsY compare
MMP_RS02240 -2.2 -3.1 methanogenesis marker 7 protein compare
MMP_RS03035 -2.2 -3.5 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS02280 -2.2 -1.0 DUF211 domain-containing protein compare
MMP_RS05265 -2.2 -2.0 2-isopropylmalate synthase compare
MMP_RS06120 -2.1 -1.6 UPF0147 family protein compare
MMP_RS07615 -2.1 -7.1 energy-coupling factor ABC transporter permease compare
MMP_RS07630 -2.1 -1.7 ATP-binding cassette domain-containing protein compare
MMP_RS01005 -2.0 -0.9 riboflavin synthase compare
MMP_RS03550 -2.0 -2.5 DUF2124 domain-containing protein compare
MMP_RS08595 -2.0 -1.2 flagellar protein C compare
MMP_RS07620 -2.0 -4.8 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS05865 -2.0 -3.6 hypothetical protein compare
MMP_RS06895 -2.0 -1.4 selenocysteine-specific translation elongation factor compare
MMP_RS07730 -2.0 -1.7 pyruvate synthase subunit beta compare
MMP_RS01265 -2.0 -2.1 hypothetical protein compare
MMP_RS00685 -2.0 -3.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS02195 -2.0 -3.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS03640 -1.9 -2.7 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS04775 -1.9 -2.8 adenosylhomocysteinase compare
MMP_RS01795 -1.9 -1.3 methanogenesis marker 6 protein compare
MMP_RS01700 -1.9 -1.0 dihydroxy-acid dehydratase compare
MMP_RS06630 -1.8 -0.6 UPF0058 family protein compare
MMP_RS03305 -1.8 -7.8 winged helix-turn-helix domain-containing protein compare
MMP_RS08210 -1.8 -1.8 phosphatidylglycerophosphatase A compare
MMP_RS05765 -1.8 -4.8 M42 family metallopeptidase compare
MMP_RS00295 -1.8 -1.6 gamma carbonic anhydrase family protein compare
MMP_RS05930 -1.8 -2.1 3-isopropylmalate dehydratase large subunit compare
MMP_RS07200 -1.8 -4.9 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05245 -1.7 -7.5 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS03555 -1.7 -6.3 transcriptional regulator compare
MMP_RS03205 -1.7 -1.4 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS02800 -1.7 -4.7 nucleotidyltransferase domain-containing protein compare
MMP_RS01250 -1.7 -5.8 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS03300 -1.7 -0.7 TOBE domain-containing protein compare
MMP_RS05525 -1.7 -4.6 calcium/sodium antiporter compare
MMP_RS02340 -1.6 -2.1 DNA-directed RNA polymerase subunit E'' compare
MMP_RS07420 -1.6 -2.8 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS09020 -1.6 -1.2 hypothetical protein compare
MMP_RS08840 -1.6 -6.5 class I SAM-dependent methyltransferase compare
MMP_RS01980 -1.6 -9.7 trimeric intracellular cation channel family protein compare
MMP_RS00520 -1.6 -1.0 RNA polymerase Rpb4 family protein compare
MMP_RS01840 -1.5 -5.2 TIGR00289 family protein compare
MMP_RS07765 -1.5 -6.2 sodium:alanine symporter family protein compare
MMP_RS03095 -1.5 -4.3 diphthine synthase compare
MMP_RS02345 -1.5 -2.9 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS01725 -1.5 -2.7 class I SAM-dependent methyltransferase family protein compare
MMP_RS06885 -1.5 -2.0 50S ribosome-binding GTPase compare
MMP_RS01220 -1.4 -5.7 hypothetical protein compare
MMP_RS06105 -1.4 -6.4 hydrogenase maturation peptidase HycI compare
MMP_RS08785 -1.4 -0.9 RNA-protein complex protein Nop10 compare
MMP_RS00040 -1.4 -5.0 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS00110 -1.4 -2.8 hypothetical protein compare
MMP_RS06855 -1.4 -6.4 hypothetical protein compare
MMP_RS05815 -1.4 -1.6 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08445 -1.4 -3.2 DUF2099 family protein compare
MMP_RS07845 -1.4 -1.1 LL-diaminopimelate aminotransferase compare
MMP_RS08590 -1.3 -4.4 flagellin compare
MMP_RS01985 -1.3 -2.0 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS05555 -1.3 -1.2 DUF4040 domain-containing protein compare
MMP_RS07575 -1.3 -2.9 RNA ligase partner protein compare
MMP_RS01865 -1.3 -1.3 GPR1/FUN34/YaaH family transporter compare
MMP_RS02355 -1.3 -1.6 30S ribosomal protein S27ae compare
MMP_RS00730 -1.2 -2.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS05295 -1.2 -6.4 minichromosome maintenance protein MCM compare
MMP_RS07695 -1.2 -4.4 DUF3236 domain-containing protein compare
MMP_RS08440 -1.2 -2.3 cell division protein SepF compare
MMP_RS04090 -1.2 -2.0 hypothetical protein compare
MMP_RS00315 -1.2 -4.8 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS00810 -1.2 -4.8 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS08300 -1.2 -0.8 metal-sulfur cluster assembly factor compare
MMP_RS08200 -1.2 -7.6 archaeosine synthase subunit alpha compare
MMP_RS05060 -1.2 -8.1 AAA family ATPase compare
MMP_RS06930 -1.2 -6.0 MBL fold metallo-hydrolase compare
MMP_RS05920 -1.2 -0.4 50S ribosomal protein L37e compare
MMP_RS03110 -1.2 -3.7 glycosyltransferase family 2 protein compare
MMP_RS07365 -1.2 -5.1 2-phosphoglycerate kinase compare
MMP_RS05250 -1.2 -2.2 NFYB/HAP3 family transcription factor subunit compare
MMP_RS07385 -1.1 -2.0 protein translocase SEC61 complex subunit gamma compare
MMP_RS05345 -1.1 -3.4 hypothetical protein compare
MMP_RS01830 -1.1 -1.1 tRNA-Val compare
MMP_RS06840 -1.1 -0.7 DNA-directed RNA polymerase subunit N compare
MMP_RS05075 -1.1 -6.7 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS06760 -1.1 -2.8 hypothetical protein compare
MMP_RS05100 -1.1 -7.4 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS05085 -1.1 -5.3 AAA family ATPase compare
MMP_RS00720 -1.1 -5.1 metal-dependent hydrolase compare
MMP_RS06925 -1.1 -1.3 ribonuclease VapC4 compare
MMP_RS02175 -1.1 -0.7 DUF1611 domain-containing protein compare
MMP_RS02135 -1.1 -2.2 DUF5612 domain-containing protein compare
MMP_RS05800 -1.1 -4.7 B12-binding domain-containing radical SAM protein compare
MMP_RS08745 -1.1 -4.2 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06865 -1.1 -0.9 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS06200 -1.0 -3.8 M24 family metallopeptidase compare
MMP_RS02130 -1.0 -3.9 zinc metalloprotease HtpX compare
MMP_RS05090 -1.0 -4.5 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS01495 -1.0 -4.9 TraB/GumN family protein compare
MMP_RS06725 -1.0 -3.6 hypothetical protein compare
MMP_RS06295 -1.0 -2.3 methanogenesis marker 14 protein compare
MMP_RS00290 -1.0 -4.2 hypothetical protein compare
MMP_RS07605 -1.0 -1.4 diadenylate cyclase compare
MMP_RS07580 -1.0 -1.7 DUF356 domain-containing protein compare
MMP_RS06600 -1.0 -0.9 class III signal peptide-containing protein compare
MMP_RS05080 -1.0 -7.0 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS05070 -1.0 -3.4 4Fe-4S dicluster domain-containing protein compare
MMP_RS01365 -1.0 -2.3 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS05095 -1.0 -3.6 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS01045 -1.0 -3.5 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS04195 -1.0 -2.3 flavodoxin compare
MMP_RS00060 -1.0 -1.3 3-dehydroquinate synthase II compare
MMP_RS02605 -1.0 -0.7 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS07350 -1.0 -1.1 preprotein translocase subunit Sec61beta compare
MMP_RS07685 -0.9 -3.4 TIGR01212 family radical SAM protein compare
MMP_RS05280 -0.9 -4.7 COG1361 S-layer family protein compare
MMP_RS07425 -0.9 -2.2 GTP-binding protein compare
MMP_RS07700 -0.9 -5.2 DUF1188 domain-containing protein compare
MMP_RS08195 -0.9 -4.8 hypothetical protein compare
MMP_RS03585 -0.9 -2.2 Hsp20/alpha crystallin family protein compare
MMP_RS05285 -0.9 -3.7 MMPL family transporter compare
MMP_RS03440 -0.9 -0.8 MoaD/ThiS family protein compare
MMP_RS02170 -0.9 -2.6 CBS domain-containing protein compare
MMP_RS06710 -0.9 -2.6 selenium-binding protein compare
MMP_RS03120 -0.9 -1.4 hypothetical protein compare
MMP_RS02190 -0.8 -1.6 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS06525 -0.8 -0.8 YciI family protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Polymyxin B sulfate across organisms