Experiment set13S615 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Sulfaquinoxaline sodium salt 0.1 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS06355 -7.2 -2.5 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS07600 -5.9 -2.4 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06730 -5.7 -2.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS06285 -5.6 -2.2 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07630 -5.2 -1.8 ATP-binding cassette domain-containing protein compare
MMP_RS05835 -5.1 -1.0 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS03445 -5.1 -1.0 methanogenesis marker 17 protein compare
MMP_RS06895 -4.8 -1.6 selenocysteine-specific translation elongation factor compare
MMP_RS08715 -4.5 -1.8 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07860 -4.4 -0.9 hypothetical protein compare
MMP_RS07625 -4.2 -3.6 cobalt ECF transporter T component CbiQ compare
MMP_RS02900 -4.1 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS08720 -4.0 -1.6 4Fe-4S binding protein compare
MMP_RS06345 -3.9 -6.4 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS00300 -3.9 -0.8 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS03315 -3.9 -1.3 ferrous iron transport protein A compare
MMP_RS03600 -3.8 -2.7 triose-phosphate isomerase compare
MMP_RS00685 -3.7 -3.1 2-phospho-L-lactate guanylyltransferase compare
MMP_RS03015 -3.7 -5.1 GTP 3' 8-cyclase MoaA compare
MMP_RS03475 -3.7 -0.7 hypothetical protein compare
MMP_RS01385 -3.6 -0.7 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01755 -3.5 -1.0 DUF2097 domain-containing protein compare
MMP_RS08650 -3.5 -4.0 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS05515 -3.5 -4.2 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS08635 -3.4 -1.7 UbiA family prenyltransferase compare
MMP_RS06680 -3.4 -5.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS07635 -3.4 -5.2 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08300 -3.4 -1.1 metal-sulfur cluster assembly factor compare
MMP_RS07005 -3.4 -0.7 4Fe-4S binding protein compare
MMP_RS06315 -3.3 -0.9 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS06685 -3.2 -8.0 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS04890 -3.2 -0.9 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS05920 -3.2 -0.6 50S ribosomal protein L37e compare
MMP_RS00130 -3.1 -1.6 nickel-responsive transcriptional regulator NikR compare
MMP_RS00520 -3.0 -1.9 RNA polymerase Rpb4 family protein compare
MMP_RS07545 -3.0 -0.8 HTH domain-containing protein compare
MMP_RS01175 -3.0 -2.3 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03640 -2.9 -2.8 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS00110 -2.8 -3.6 hypothetical protein compare
MMP_RS08790 -2.8 -2.7 translation initiation factor IF-2 subunit alpha compare
MMP_RS03025 -2.7 -3.6 molybdenum cofactor guanylyltransferase compare
MMP_RS01800 -2.7 -3.2 TIGR00303 family protein compare
MMP_RS04685 -2.7 -2.5 DUF126 domain-containing protein compare
MMP_RS06295 -2.7 -4.6 methanogenesis marker 14 protein compare
MMP_RS06350 -2.6 -5.6 HesA/MoeB/ThiF family protein compare
MMP_RS02340 -2.6 -2.4 DNA-directed RNA polymerase subunit E'' compare
MMP_RS07755 -2.5 -1.3 DUF555 domain-containing protein compare
MMP_RS04585 -2.5 -7.0 AIR synthase related protein compare
MMP_RS06700 -2.5 -6.1 hypothetical protein compare
MMP_RS09020 -2.5 -1.5 hypothetical protein compare
MMP_RS02165 -2.4 -5.7 tRNA-dihydrouridine synthase compare
MMP_RS06630 -2.4 -0.7 UPF0058 family protein compare
MMP_RS03580 -2.4 -3.2 signal recognition particle-docking protein FtsY compare
MMP_RS08435 -2.3 -1.8 Era-like GTP-binding protein compare
MMP_RS03035 -2.2 -3.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS06720 -2.2 -3.6 response regulator transcription factor compare
MMP_RS08460 -2.2 -2.4 proteasome-activating nucleotidase compare
MMP_RS02240 -2.2 -2.4 methanogenesis marker 7 protein compare
MMP_RS07200 -2.2 -3.6 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06230 -2.1 -2.6 helix-turn-helix domain-containing protein compare
MMP_RS06270 -2.1 -4.6 TIGR00300 family protein compare
MMP_RS06110 -2.1 -2.5 ATP-dependent protease LonB compare
MMP_RS00945 -2.0 -1.5 PadR family transcriptional regulator compare
MMP_RS02875 -2.0 -7.1 chorismate pyruvate-lyase family protein compare
MMP_RS08210 -2.0 -1.5 phosphatidylglycerophosphatase A compare
MMP_RS02790 -2.0 -1.3 class III signal peptide-containing protein compare
MMP_RS02605 -2.0 -1.1 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS06020 -1.9 -2.3 archaeoflavoprotein AfpA compare
MMP_RS05865 -1.9 -4.5 hypothetical protein compare
MMP_RS06885 -1.9 -1.6 50S ribosome-binding GTPase compare
MMP_RS02135 -1.9 -3.3 DUF5612 domain-containing protein compare
MMP_RS01225 -1.9 -2.5 DUF5379 domain-containing protein compare
MMP_RS07390 -1.9 -2.0 cell division protein FtsZ compare
MMP_RS06715 -1.8 -5.8 cache domain-containing protein compare
MMP_RS03305 -1.8 -5.0 winged helix-turn-helix domain-containing protein compare
MMP_RS03110 -1.8 -4.7 glycosyltransferase family 2 protein compare
MMP_RS06770 -1.8 -6.4 DHH family phosphoesterase compare
MMP_RS02170 -1.8 -5.2 CBS domain-containing protein compare
MMP_RS01545 -1.8 -1.2 CBS domain-containing protein compare
MMP_RS01700 -1.7 -0.9 dihydroxy-acid dehydratase compare
MMP_RS03095 -1.7 -3.7 diphthine synthase compare
MMP_RS01100 -1.7 -1.5 ABC transporter ATP-binding protein compare
MMP_RS06120 -1.7 -1.3 UPF0147 family protein compare
MMP_RS05845 -1.7 -1.4 tRNA-intron lyase compare
MMP_RS03555 -1.6 -3.6 transcriptional regulator compare
MMP_RS01265 -1.6 -2.9 hypothetical protein compare
MMP_RS03300 -1.6 -0.7 TOBE domain-containing protein compare
MMP_RS07380 -1.5 -1.1 transcription elongation factor Spt5 compare
MMP_RS05430 -1.5 -2.8 TIGR00288 family NYN domain-containing protein compare
MMP_RS02230 -1.5 -6.3 sodium-dependent transporter compare
MMP_RS05930 -1.5 -2.0 3-isopropylmalate dehydratase large subunit compare
MMP_RS05545 -1.5 -4.1 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS07540 -1.5 -3.4 CBS domain-containing protein compare
MMP_RS01365 -1.5 -1.3 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS00115 -1.5 -6.8 radical SAM protein compare
MMP_RS07960 -1.5 -3.5 sugar phosphate isomerase/epimerase compare
MMP_RS02010 -1.5 -5.7 PHP domain-containing protein compare
MMP_RS02345 -1.4 -2.3 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS04775 -1.4 -1.9 adenosylhomocysteinase compare
MMP_RS05250 -1.4 -1.7 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08645 -1.4 -4.3 UPF0179 family protein compare
MMP_RS01985 -1.4 -3.1 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS05765 -1.4 -3.2 M42 family metallopeptidase compare
MMP_RS07445 -1.4 -2.9 helix-turn-helix domain-containing protein compare
MMP_RS06200 -1.4 -4.8 M24 family metallopeptidase compare
MMP_RS03145 -1.4 -4.4 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS07620 -1.4 -2.7 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS05245 -1.4 -4.3 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS02235 -1.3 -4.5 CBS domain-containing protein compare
MMP_RS06930 -1.3 -5.4 MBL fold metallo-hydrolase compare
MMP_RS02195 -1.3 -1.7 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07525 -1.3 -3.5 4Fe-4S binding protein compare
MMP_RS06340 -1.3 -4.1 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS02370 -1.2 -3.6 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS07765 -1.2 -3.9 sodium:alanine symporter family protein compare
MMP_RS08590 -1.2 -2.9 flagellin compare
MMP_RS00895 -1.2 -1.6 hypothetical protein compare
MMP_RS06475 -1.2 -2.7 FAD-dependent oxidoreductase compare
MMP_RS07615 -1.2 -2.5 energy-coupling factor ABC transporter permease compare
MMP_RS00305 -1.1 -0.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS08820 -1.1 -2.2 hypothetical protein compare
MMP_RS07845 -1.1 -0.8 LL-diaminopimelate aminotransferase compare
MMP_RS08615 -1.1 -1.8 flagellar protein G compare
MMP_RS02410 -1.1 -1.7 ABC transporter substrate-binding protein compare
MMP_RS08440 -1.1 -1.1 cell division protein SepF compare
MMP_RS06175 -1.1 -3.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS04500 -1.1 -6.8 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS04870 -1.1 -2.5 TIGR02253 family HAD-type hydrolase compare
MMP_RS01830 -1.1 -0.9 tRNA-Val compare
MMP_RS08200 -1.1 -6.5 archaeosine synthase subunit alpha compare
MMP_RS02175 -1.1 -0.7 DUF1611 domain-containing protein compare
MMP_RS06975 -1.0 -1.2 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS06370 -1.0 -2.3 biotin synthase BioB compare
MMP_RS05295 -1.0 -4.6 minichromosome maintenance protein MCM compare
MMP_RS06855 -1.0 -4.0 hypothetical protein compare
MMP_RS08095 -1.0 -2.7 dethiobiotin synthase compare
MMP_RS05800 -1.0 -4.2 B12-binding domain-containing radical SAM protein compare
MMP_RS05555 -1.0 -1.0 DUF4040 domain-containing protein compare
MMP_RS02045 -1.0 -1.2 tRNA-Met compare
MMP_RS01720 -1.0 -1.1 replication factor C large subunit compare
MMP_RS04710 -1.0 -0.6 hypothetical protein compare
MMP_RS03400 -1.0 -0.9 archease compare
MMP_RS04485 -1.0 -4.7 putative beta-lysine N-acetyltransferase compare
MMP_RS01220 -1.0 -2.1 hypothetical protein compare
MMP_RS01840 -1.0 -3.8 TIGR00289 family protein compare
MMP_RS01795 -0.9 -0.6 methanogenesis marker 6 protein compare
MMP_RS00915 -0.9 -2.4 DUF116 domain-containing protein compare
MMP_RS01500 -0.9 -1.0 CBS domain-containing protein compare
MMP_RS08840 -0.9 -3.7 class I SAM-dependent methyltransferase compare
MMP_RS00050 -0.9 -3.7 AarF/UbiB family protein compare
MMP_RS00385 -0.9 -2.9 P-II family nitrogen regulator compare
MMP_RS03020 -0.9 -2.2 peptidylprolyl isomerase compare
MMP_RS02355 -0.9 -1.2 30S ribosomal protein S27ae compare
MMP_RS01325 -0.9 -0.9 dihydroneopterin aldolase family protein compare
MMP_RS07385 -0.9 -1.2 protein translocase SEC61 complex subunit gamma compare
MMP_RS08745 -0.9 -2.0 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS01380 -0.9 -1.7 PHP domain-containing protein compare
MMP_RS07575 -0.9 -2.9 RNA ligase partner protein compare
MMP_RS03140 -0.9 -3.7 hypothetical protein compare
MMP_RS00725 -0.9 -3.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS05020 -0.9 -1.3 hypothetical protein compare
MMP_RS01655 -0.9 -1.2 DsrE family protein compare
MMP_RS06900 -0.9 -1.3 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS06290 -0.9 -2.5 DNA repair and recombination protein RadA compare
MMP_RS06130 -0.8 -1.3 peptidylprolyl isomerase compare
MMP_RS07685 -0.8 -2.8 TIGR01212 family radical SAM protein compare
MMP_RS06705 -0.8 -2.1 formate/nitrite transporter family protein compare
MMP_RS00810 -0.8 -2.4 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS00185 -0.8 -5.3 potassium channel protein compare
MMP_RS05510 -0.8 -1.9 Rrf2 family transcriptional regulator compare
MMP_RS04850 -0.8 -5.4 UPF0254 family protein compare
MMP_RS08555 -0.8 -2.6 hypothetical protein compare
MMP_RS02955 -0.8 -1.8 DJ-1/PfpI family protein compare
MMP_RS07645 -0.8 -2.7 aldehyde dehydrogenase family protein compare
MMP_RS02695 -0.8 -3.3 formylmethanofuran dehydrogenase subunit A compare
MMP_RS01575 -0.8 -2.9 aldolase compare
MMP_RS01005 -0.8 -0.6 riboflavin synthase compare
MMP_RS00620 -0.8 -2.5 4Fe-4S binding protein compare
MMP_RS01250 -0.8 -3.9 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS02705 -0.8 -2.3 formylmethanofuran dehydrogenase subunit B compare
MMP_RS05060 -0.8 -3.5 AAA family ATPase compare
MMP_RS08595 -0.8 -0.8 flagellar protein C compare
MMP_RS03385 -0.8 -0.6 cation diffusion facilitator family transporter compare
MMP_RS08100 -0.8 -2.3 8-amino-7-oxononanoate synthase compare
MMP_RS01020 -0.7 -0.5 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS02100 -0.7 -2.0 metallophosphoesterase compare
MMP_RS08930 -0.7 -0.8 hypothetical protein compare
MMP_RS08225 -0.7 -2.9 RimK family alpha-L-glutamate ligase compare
MMP_RS00290 -0.7 -2.6 hypothetical protein compare
MMP_RS04195 -0.7 -1.6 flavodoxin compare
MMP_RS01980 -0.7 -3.8 trimeric intracellular cation channel family protein compare
MMP_RS07350 -0.7 -0.8 preprotein translocase subunit Sec61beta compare
MMP_RS01600 -0.7 -1.1 50S ribosomal protein L15e compare
MMP_RS00040 -0.7 -1.8 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS06105 -0.7 -1.6 hydrogenase maturation peptidase HycI compare
MMP_RS00720 -0.7 -1.9 metal-dependent hydrolase compare
MMP_RS05355 -0.7 -0.5 hypothetical protein compare
MMP_RS08690 -0.7 -2.8 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS02965 -0.7 -1.4 carboxymuconolactone decarboxylase family protein compare
MMP_RS06865 -0.7 -0.7 HypC/HybG/HupF family hydrogenase formation chaperone compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sulfaquinoxaline sodium salt across organisms