Experiment set13S608 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Sodium phosphite dibasic pentahydrate 100 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS03385 +2.7 3.7 cation diffusion facilitator family transporter compare
MMP_RS01370 +1.6 10.1 acetate--CoA ligase family protein compare
MMP_RS07415 +1.5 5.5 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS05355 +1.4 1.7 hypothetical protein compare
MMP_RS01960 +1.4 1.5 hypothetical protein compare
MMP_RS07955 +1.2 5.6 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS00750 +1.1 1.9 fumarate hydratase compare
MMP_RS00395 +1.1 2.2 MGMT family protein compare
MMP_RS01570 +1.0 2.1 hypothetical protein compare
MMP_RS01775 +1.0 2.0 TIGR00297 family protein compare
MMP_RS00675 +0.9 1.1 nitroreductase family protein compare
MMP_RS06540 +0.9 2.7 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS02885 +0.9 7.4 molybdopterin biosynthesis protein compare
MMP_RS02805 +0.9 1.2 HEPN domain-containing protein compare
MMP_RS07895 +0.8 3.5 cytochrome c compare
MMP_RS08275 +0.8 4.1 hypothetical protein compare
MMP_RS07125 +0.8 2.0 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS06575 +0.8 4.3 fluoride efflux transporter CrcB compare
MMP_RS07850 +0.7 2.4 prephenate dehydratase compare
MMP_RS06310 +0.7 1.8 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS08660 +0.7 3.4 DHH family phosphoesterase compare
MMP_RS07555 +0.7 0.5 monovalent cation/H+ antiporter subunit E compare
MMP_RS08340 +0.7 2.2 4Fe-4S binding protein compare
MMP_RS07705 +0.7 3.2 transcriptional regulator compare
MMP_RS06555 +0.7 1.9 cupin domain-containing protein compare
MMP_RS05770 +0.6 2.6 YkgJ family cysteine cluster protein compare
MMP_RS06535 +0.6 2.1 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS03320 +0.6 2.3 metal-dependent transcriptional regulator compare
MMP_RS08370 +0.6 0.4 cation:proton antiporter subunit C compare
MMP_RS07435 +0.6 0.8 GMP synthase subunit A compare
MMP_RS01055 +0.6 2.8 hypothetical protein compare
MMP_RS06860 +0.6 0.9 4Fe-4S binding protein compare
MMP_RS07840 +0.6 1.9 ribonuclease III compare
MMP_RS07815 +0.6 0.8 DUF2120 domain-containing protein compare
MMP_RS01180 +0.6 0.8 XTP/dITP diphosphatase compare
MMP_RS01650 +0.6 0.6 sulfurtransferase TusA family protein compare
MMP_RS00670 +0.6 2.2 TIM barrel protein compare
MMP_RS01880 +0.6 1.8 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS03215 +0.5 3.3 MBL fold metallo-hydrolase compare
MMP_RS08320 +0.5 2.2 molybdopterin molybdotransferase MoeA compare
MMP_RS04695 +0.5 1.9 selenide water dikinase SelD compare
MMP_RS01925 +0.5 2.0 DUF1616 domain-containing protein compare
MMP_RS06570 +0.5 1.9 DUF190 domain-containing protein compare
MMP_RS08355 +0.5 2.4 Na(+)/H(+) antiporter subunit B compare
MMP_RS05970 +0.5 1.5 class II SORL domain-containing protein compare
MMP_RS05955 +0.5 1.2 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS04100 +0.5 2.1 hypothetical protein compare
MMP_RS00960 +0.5 1.8 iron export ABC transporter permease subunit FetB compare
MMP_RS08215 +0.5 1.8 DUF483 domain-containing protein compare
MMP_RS06480 +0.5 2.9 ABC transporter substrate-binding protein compare
MMP_RS08455 +0.5 2.3 multiprotein bridging factor aMBF1 compare
MMP_RS00665 +0.5 1.0 hypothetical protein compare
MMP_RS05720 +0.5 1.6 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS05940 +0.5 2.2 corrinoid protein compare
MMP_RS05360 +0.5 1.8 hypothetical protein compare
MMP_RS01435 +0.5 2.1 DMT family transporter compare
MMP_RS02300 +0.5 1.9 NAD(P)H-dependent oxidoreductase compare
MMP_RS00080 +0.5 2.4 RecB-family nuclease compare
MMP_RS08995 +0.5 0.7 hypothetical protein compare
MMP_RS00400 +0.4 1.5 tributyrin esterase compare
MMP_RS00740 +0.4 1.6 cyclase family protein compare
MMP_RS05535 +0.4 1.2 hypothetical protein compare
MMP_RS01940 +0.4 1.4 MoxR family ATPase compare
MMP_RS03270 +0.4 2.3 ADP-ribosylglycohydrolase family protein compare
MMP_RS02130 +0.4 1.5 zinc metalloprotease HtpX compare
MMP_RS02880 +0.4 2.5 AmmeMemoRadiSam system radical SAM enzyme compare
MMP_RS08315 +0.4 1.5 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS01620 +0.4 1.1 hypothetical protein compare
MMP_RS04620 +0.4 2.5 cobalt transporter CbiM compare
MMP_RS00940 +0.4 2.7 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS06190 +0.4 2.5 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO compare
MMP_RS01525 +0.4 0.9 nucleoside-diphosphate kinase compare
MMP_RS02010 +0.4 1.5 PHP domain-containing protein compare
MMP_RS08760 +0.4 1.3 hypothetical protein compare
MMP_RS00990 +0.4 1.4 hypothetical protein compare
MMP_RS04145 +0.4 0.8 hypothetical protein compare
MMP_RS03675 +0.4 2.8 RimK family alpha-L-glutamate ligase compare
MMP_RS00705 +0.4 1.2 hypothetical protein compare
MMP_RS06500 +0.4 1.9 ATP-binding protein compare
MMP_RS05365 +0.4 1.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS08350 +0.4 0.4 hypothetical protein compare
MMP_RS02605 +0.4 0.4 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS01805 +0.4 1.1 NUDIX hydrolase compare
MMP_RS02595 +0.4 0.5 putative zinc-binding protein compare
MMP_RS01885 +0.4 1.1 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS07835 +0.4 1.1 TldD/PmbA family protein compare
MMP_RS00430 +0.4 1.7 hypothetical protein compare
MMP_RS08335 +0.4 1.4 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS06910 +0.4 1.8 RlmF-related methyltransferase compare
MMP_RS01150 +0.4 1.6 aldo/keto reductase compare
MMP_RS02895 +0.4 2.1 DHH family phosphoesterase compare
MMP_RS06485 +0.4 0.3 zinc ribbon domain-containing protein compare
MMP_RS07145 +0.4 2.0 AmmeMemoRadiSam system protein B compare
MMP_RS03870 +0.4 1.7 purine NTPase compare
MMP_RS06585 +0.4 0.6 DMT family protein compare
MMP_RS01900 +0.4 2.0 hypothetical protein compare
MMP_RS01210 +0.4 1.9 sodium:solute symporter compare
MMP_RS08430 +0.4 1.7 HAD family hydrolase compare
MMP_RS07130 +0.3 1.9 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS07855 +0.3 1.8 class I SAM-dependent methyltransferase compare
MMP_RS07650 +0.3 2.6 TldD/PmbA family protein compare
MMP_RS01415 +0.3 1.2 DUF2067 domain-containing protein compare
MMP_RS00630 +0.3 2.2 ECF transporter S component compare
MMP_RS00530 +0.3 1.2 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS03740 +0.3 1.2 indolepyruvate oxidoreductase subunit beta compare
MMP_RS08175 +0.3 1.4 7-cyano-7-deazaguanine synthase compare
MMP_RS01630 +0.3 1.6 N-glycosylase/DNA lyase compare
MMP_RS03100 +0.3 1.4 hypothetical protein compare
MMP_RS00770 +0.3 1.3 hypothetical protein compare
MMP_RS00650 +0.3 1.7 ABC transporter ATP-binding protein compare
MMP_RS05495 +0.3 2.0 hypothetical protein compare
MMP_RS04720 +0.3 0.7 DedA family protein compare
MMP_RS03420 +0.3 1.3 acetolactate synthase small subunit compare
MMP_RS06525 +0.3 0.4 YciI family protein compare
MMP_RS07590 +0.3 2.1 hypothetical protein compare
MMP_RS08395 +0.3 1.3 DsrE family protein compare
MMP_RS07725 +0.3 1.1 4Fe-4S dicluster domain-containing protein compare
MMP_RS00085 +0.3 1.9 DNA cytosine methyltransferase compare
MMP_RS06075 +0.3 1.5 class I SAM-dependent methyltransferase compare
MMP_RS00565 +0.3 1.4 CBS domain-containing protein compare
MMP_RS05975 +0.3 1.5 hypothetical protein compare
MMP_RS00800 +0.3 1.7 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS08160 +0.3 1.8 EamA family transporter compare
MMP_RS07960 +0.3 1.3 sugar phosphate isomerase/epimerase compare
MMP_RS08380 +0.3 1.8 phosphatase PAP2 family protein compare
MMP_RS08415 +0.3 0.7 radical SAM protein compare
MMP_RS07540 +0.3 1.0 CBS domain-containing protein compare
MMP_RS08310 +0.3 0.7 TMEM165/GDT1 family protein compare
MMP_RS08235 +0.3 1.7 hypothetical protein compare
MMP_RS05980 +0.3 1.6 ferritin compare
MMP_RS02675 +0.3 0.6 hypothetical protein compare
MMP_RS00795 +0.3 1.8 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS03910 +0.3 0.8 hypothetical protein compare
MMP_RS05140 +0.3 0.7 helix-turn-helix transcriptional regulator compare
MMP_RS03485 +0.3 0.9 TIGR00267 family protein compare
MMP_RS05835 +0.3 0.3 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS06225 +0.3 1.4 DNA double-strand break repair nuclease NurA compare
MMP_RS04050 +0.3 1.3 hypothetical protein compare
MMP_RS01990 +0.3 0.9 hypothetical protein compare
MMP_RS07890 +0.3 0.6 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS02785 +0.3 0.9 MarR family transcriptional regulator compare
MMP_RS05695 +0.3 0.9 phospholipase D-like domain-containing protein compare
MMP_RS04580 +0.3 1.8 hypothetical protein compare
MMP_RS04520 +0.3 1.1 nucleoside deaminase compare
MMP_RS07595 +0.3 1.7 hypothetical protein compare
MMP_RS06550 +0.3 1.3 AMP-binding protein compare
MMP_RS01920 +0.3 1.7 glycosyltransferase family 2 protein compare
MMP_RS01875 +0.3 1.3 N-acetyltransferase compare
MMP_RS06490 +0.3 1.0 hypothetical protein compare
MMP_RS05150 +0.3 1.5 hypothetical protein compare
MMP_RS06545 +0.3 1.3 ferredoxin family protein compare
MMP_RS03325 +0.3 1.2 hypothetical protein compare
MMP_RS03395 +0.3 1.1 hypothetical protein compare
MMP_RS03150 +0.3 1.4 phosphoglycerate mutase compare
MMP_RS04945 +0.3 1.0 hypothetical protein compare
MMP_RS02495 +0.3 0.6 hypothetical protein compare
MMP_RS02735 +0.3 1.3 MBL fold metallo-hydrolase compare
MMP_RS03760 +0.3 1.7 hypothetical protein compare
MMP_RS03585 +0.3 0.9 Hsp20/alpha crystallin family protein compare
MMP_RS04175 +0.3 1.8 permease compare
MMP_RS00950 +0.2 1.4 site-2 protease family protein compare
MMP_RS00155 +0.2 1.3 heavy metal-binding domain-containing protein compare
MMP_RS04270 +0.2 1.0 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS00855 +0.2 0.7 DUF367 family protein compare
MMP_RS08685 +0.2 1.9 hypothetical protein compare
MMP_RS08770 +0.2 1.0 hypothetical protein compare
MMP_RS02970 +0.2 1.6 hypothetical protein compare
MMP_RS04840 +0.2 1.6 response regulator compare
MMP_RS03980 +0.2 0.9 hypothetical protein compare
MMP_RS02590 +0.2 1.4 low molecular weight phosphatase family protein compare
MMP_RS05450 +0.2 0.8 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS01780 +0.2 0.8 TrmJ/YjtD family RNA methyltransferase compare
MMP_RS04205 +0.2 1.2 carboxymuconolactone decarboxylase family protein compare
MMP_RS08345 +0.2 1.2 4Fe-4S binding protein compare
MMP_RS01130 +0.2 1.0 flavoprotein compare
MMP_RS00980 +0.2 1.3 hypothetical protein compare
MMP_RS06870 +0.2 0.9 DedA family protein compare
MMP_RS06495 +0.2 0.8 YkgJ family cysteine cluster protein compare
MMP_RS07715 +0.2 1.3 YfcE family phosphodiesterase compare
MMP_RS02480 +0.2 0.5 hypothetical protein compare
MMP_RS00825 +0.2 1.1 fumarylacetoacetate hydrolase family protein compare
MMP_RS01675 +0.2 0.4 hypothetical protein compare
MMP_RS07560 +0.2 1.1 prefoldin subunit alpha compare
MMP_RS05455 +0.2 1.4 DUF167 domain-containing protein compare
MMP_RS01065 +0.2 1.4 alpha/beta hydrolase compare
MMP_RS03065 +0.2 0.9 AzlC family ABC transporter permease compare
MMP_RS01515 +0.2 1.4 PINc/VapC family ATPase compare
MMP_RS03115 +0.2 1.6 hypothetical protein compare
MMP_RS07095 +0.2 0.9 PspC domain-containing protein compare
MMP_RS06440 +0.2 1.2 CBS domain-containing protein compare
MMP_RS07115 +0.2 0.7 MBL fold metallo-hydrolase compare
MMP_RS08775 +0.2 0.7 methanogenesis marker 9 domain-containing protein compare
MMP_RS02415 +0.2 0.5 site-specific integrase compare
MMP_RS05470 +0.2 1.4 DUF523 and DUF1722 domain-containing protein compare
MMP_RS03450 +0.2 0.3 glycine synthesis protein GlyXS (from data) compare
MMP_RS07155 +0.2 1.0 MFS transporter compare
MMP_RS01115 +0.2 1.4 molybdopterin molybdotransferase MoeA compare
MMP_RS05530 +0.2 1.1 signal peptide peptidase SppA compare
MMP_RS06655 +0.2 1.5 glycoside hydrolase family 15 protein compare
MMP_RS00100 +0.2 1.3 tRNA pseudouridine(13) synthase TruD compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium phosphite dibasic pentahydrate across organisms