Experiment set13S603 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete Spiramycin 0.1 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS00520 -5.0 -2.1 RNA polymerase Rpb4 family protein compare
MMP_RS01500 -4.3 -2.6 CBS domain-containing protein compare
MMP_RS03445 -4.2 -1.1 methanogenesis marker 17 protein compare
MMP_RS05355 -3.9 -1.2 hypothetical protein compare
MMP_RS00515 -3.6 -0.9 DUF655 domain-containing protein compare
MMP_RS05920 -3.2 -0.6 50S ribosomal protein L37e compare
MMP_RS00130 -3.0 -1.5 nickel-responsive transcriptional regulator NikR compare
MMP_RS01545 -3.0 -1.4 CBS domain-containing protein compare
MMP_RS03600 -2.9 -2.4 triose-phosphate isomerase compare
MMP_RS06350 -2.9 -6.9 HesA/MoeB/ThiF family protein compare
MMP_RS04780 -2.8 -3.7 ribonuclease P compare
MMP_RS08210 -2.8 -2.5 phosphatidylglycerophosphatase A compare
MMP_RS01225 -2.8 -4.9 DUF5379 domain-containing protein compare
MMP_RS07630 -2.7 -1.8 ATP-binding cassette domain-containing protein compare
MMP_RS03205 -2.7 -1.8 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS04585 -2.7 -12.4 AIR synthase related protein compare
MMP_RS05515 -2.7 -5.9 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS02900 -2.6 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS07635 -2.6 -8.2 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS05845 -2.6 -1.8 tRNA-intron lyase compare
MMP_RS03960 -2.5 -1.1 hypothetical protein compare
MMP_RS03640 -2.5 -3.6 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS03015 -2.5 -8.3 GTP 3' 8-cyclase MoaA compare
MMP_RS07445 -2.5 -8.3 helix-turn-helix domain-containing protein compare
MMP_RS06355 -2.4 -2.2 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01795 -2.4 -1.5 methanogenesis marker 6 protein compare
MMP_RS08635 -2.4 -2.2 UbiA family prenyltransferase compare
MMP_RS01175 -2.3 -2.8 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS05865 -2.3 -3.1 hypothetical protein compare
MMP_RS07600 -2.3 -2.6 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS02355 -2.3 -2.3 30S ribosomal protein S27ae compare
MMP_RS00305 -2.2 -1.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS06855 -2.2 -9.9 hypothetical protein compare
MMP_RS03475 -2.2 -0.7 hypothetical protein compare
MMP_RS02875 -2.2 -10.3 chorismate pyruvate-lyase family protein compare
MMP_RS06120 -2.2 -1.9 UPF0147 family protein compare
MMP_RS02175 -2.1 -1.0 DUF1611 domain-containing protein compare
MMP_RS01020 -2.1 -1.0 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS02240 -2.1 -2.5 methanogenesis marker 7 protein compare
MMP_RS02345 -2.1 -3.2 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS07425 -2.1 -6.4 GTP-binding protein compare
MMP_RS06295 -2.1 -5.3 methanogenesis marker 14 protein compare
MMP_RS02145 -2.1 -8.6 winged helix-turn-helix transcriptional regulator compare
MMP_RS00050 -2.1 -7.0 AarF/UbiB family protein compare
MMP_RS06230 -2.1 -3.3 helix-turn-helix domain-containing protein compare
MMP_RS01800 -2.1 -3.7 TIGR00303 family protein compare
MMP_RS06925 -2.1 -2.2 ribonuclease VapC4 compare
MMP_RS03580 -2.0 -3.7 signal recognition particle-docking protein FtsY compare
MMP_RS04710 -2.0 -1.7 hypothetical protein compare
MMP_RS06895 -2.0 -1.4 selenocysteine-specific translation elongation factor compare
MMP_RS05925 -2.0 -3.9 small nuclear ribonucleoprotein compare
MMP_RS06175 -1.9 -6.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS06215 -1.9 -3.4 30S ribosomal protein S6e compare
MMP_RS07525 -1.9 -6.6 4Fe-4S binding protein compare
MMP_RS01755 -1.9 -1.1 DUF2097 domain-containing protein compare
MMP_RS01250 -1.9 -6.9 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS03035 -1.9 -2.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS07605 -1.9 -3.4 diadenylate cyclase compare
MMP_RS08645 -1.8 -7.1 UPF0179 family protein compare
MMP_RS06975 -1.8 -2.8 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS08720 -1.8 -1.3 4Fe-4S binding protein compare
MMP_RS02165 -1.8 -8.5 tRNA-dihydrouridine synthase compare
MMP_RS02010 -1.8 -6.9 PHP domain-containing protein compare
MMP_RS06840 -1.8 -1.0 DNA-directed RNA polymerase subunit N compare
MMP_RS08535 -1.8 -8.1 bis-aminopropyl spermidine synthase family protein conserved
MMP_RS01365 -1.8 -3.2 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS04870 -1.8 -4.5 TIGR02253 family HAD-type hydrolase compare
MMP_RS05550 -1.8 -0.7 cation:proton antiporter compare
MMP_RS03555 -1.8 -5.7 transcriptional regulator compare
MMP_RS03400 -1.8 -2.3 archease compare
MMP_RS01985 -1.8 -6.0 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS08790 -1.8 -2.3 translation initiation factor IF-2 subunit alpha compare
MMP_RS00685 -1.8 -3.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07625 -1.7 -3.3 cobalt ECF transporter T component CbiQ compare
MMP_RS08300 -1.7 -0.9 metal-sulfur cluster assembly factor compare
MMP_RS08715 -1.7 -1.2 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07620 -1.7 -5.3 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS05765 -1.7 -4.2 M42 family metallopeptidase compare
MMP_RS00895 -1.7 -3.2 hypothetical protein compare
MMP_RS00695 -1.7 -0.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01265 -1.6 -2.5 hypothetical protein compare
MMP_RS01610 -1.6 -2.7 hypothetical protein compare
MMP_RS03435 -1.6 -1.6 ketol-acid reductoisomerase compare
MMP_RS05815 -1.6 -2.1 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS07845 -1.6 -1.4 LL-diaminopimelate aminotransferase compare
MMP_RS06680 -1.6 -7.5 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS07685 -1.6 -7.2 TIGR01212 family radical SAM protein compare
MMP_RS00850 -1.6 -5.1 TIGR01177 family methyltransferase compare
MMP_RS07860 -1.6 -0.7 hypothetical protein compare
MMP_RS09020 -1.6 -1.0 hypothetical protein compare
MMP_RS06685 -1.5 -6.8 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS01980 -1.5 -9.5 trimeric intracellular cation channel family protein compare
MMP_RS08600 -1.5 -1.8 flagellar protein D compare
MMP_RS08820 -1.5 -3.3 hypothetical protein compare
MMP_RS07005 -1.5 -0.5 4Fe-4S binding protein compare
MMP_RS07615 -1.5 -5.1 energy-coupling factor ABC transporter permease compare
MMP_RS03305 -1.5 -6.5 winged helix-turn-helix domain-containing protein compare
MMP_RS06200 -1.5 -6.8 M24 family metallopeptidase compare
MMP_RS06345 -1.5 -6.0 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS07575 -1.5 -3.6 RNA ligase partner protein compare
MMP_RS02195 -1.5 -2.6 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS04775 -1.5 -2.8 adenosylhomocysteinase compare
MMP_RS06930 -1.5 -7.9 MBL fold metallo-hydrolase compare
MMP_RS03025 -1.5 -3.4 molybdenum cofactor guanylyltransferase compare
MMP_RS04890 -1.5 -0.7 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS05250 -1.4 -3.0 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08460 -1.4 -2.0 proteasome-activating nucleotidase compare
MMP_RS08940 -1.4 -1.3 MetS family NSS transporter small subunit compare
MMP_RS07900 -1.4 -1.7 YeeE/YedE family protein compare
MMP_RS05430 -1.4 -3.9 TIGR00288 family NYN domain-containing protein compare
MMP_RS01840 -1.4 -5.2 TIGR00289 family protein compare
MMP_RS00110 -1.4 -2.5 hypothetical protein compare
MMP_RS06270 -1.4 -3.6 TIGR00300 family protein compare
MMP_RS02800 -1.4 -5.0 nucleotidyltransferase domain-containing protein compare
MMP_RS06340 -1.4 -4.7 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07755 -1.4 -0.8 DUF555 domain-containing protein compare
MMP_RS00125 -1.4 -1.3 DUF2798 domain-containing protein compare
MMP_RS07200 -1.4 -4.0 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05365 -1.4 -1.8 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS07580 -1.3 -2.7 DUF356 domain-containing protein compare
MMP_RS07750 -1.3 -3.9 DUF357 domain-containing protein compare
MMP_RS07365 -1.3 -6.4 2-phosphoglycerate kinase compare
MMP_RS03095 -1.3 -4.8 diphthine synthase compare
MMP_RS00295 -1.3 -1.6 gamma carbonic anhydrase family protein compare
MMP_RS06110 -1.3 -2.9 ATP-dependent protease LonB compare
MMP_RS01700 -1.3 -0.9 dihydroxy-acid dehydratase compare
MMP_RS00725 -1.3 -5.4 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS03440 -1.2 -1.1 MoaD/ThiS family protein compare
MMP_RS00315 -1.2 -4.6 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS08225 -1.2 -6.1 RimK family alpha-L-glutamate ligase compare
MMP_RS09025 -1.2 -1.0 hypothetical protein compare
MMP_RS05545 -1.2 -4.5 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS06400 -1.2 -0.9 4Fe-4S binding protein compare
MMP_RS03315 -1.2 -0.7 ferrous iron transport protein A compare
MMP_RS08370 -1.2 -0.5 cation:proton antiporter subunit C compare
MMP_RS05155 -1.2 -3.7 hypothetical protein compare
MMP_RS01665 -1.2 -2.6 DUF2111 domain-containing protein compare
MMP_RS00730 -1.2 -5.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS06980 -1.1 -4.4 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS01005 -1.1 -0.9 riboflavin synthase compare
MMP_RS06625 -1.1 -1.4 DNA primase compare
MMP_RS02135 -1.1 -2.9 DUF5612 domain-containing protein compare
MMP_RS07535 -1.1 -5.3 4Fe-4S binding protein compare
MMP_RS04685 -1.1 -1.7 DUF126 domain-containing protein compare
MMP_RS05830 -1.1 -2.8 peptidyl-prolyl cis-trans isomerase compare
MMP_RS00735 -1.1 -3.1 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS03550 -1.1 -1.1 DUF2124 domain-containing protein compare
MMP_RS05295 -1.1 -4.7 minichromosome maintenance protein MCM compare
MMP_RS05445 -1.1 -4.2 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS05800 -1.1 -4.8 B12-binding domain-containing radical SAM protein compare
MMP_RS03220 -1.1 -2.1 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS00040 -1.1 -3.8 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS03120 -1.1 -2.0 hypothetical protein compare
MMP_RS05060 -1.0 -6.3 AAA family ATPase compare
MMP_RS03590 -1.0 -3.1 METTL5 family protein compare
MMP_RS05540 -1.0 -1.8 hypothetical protein compare
MMP_RS01380 -1.0 -1.6 PHP domain-containing protein compare
MMP_RS05510 -1.0 -2.7 Rrf2 family transcriptional regulator compare
MMP_RS06130 -1.0 -2.0 peptidylprolyl isomerase compare
MMP_RS01495 -1.0 -4.2 TraB/GumN family protein compare
MMP_RS06730 -1.0 -0.8 phosphopantothenate/pantothenate synthetase compare
MMP_RS03225 -1.0 -2.1 acetolactate decarboxylase compare
MMP_RS05265 -1.0 -1.3 2-isopropylmalate synthase compare
MMP_RS07695 -1.0 -2.9 DUF3236 domain-containing protein compare
MMP_RS04850 -1.0 -7.0 UPF0254 family protein compare
MMP_RS08570 -1.0 -5.1 coenzyme F420-0:L-glutamate ligase compare
MMP_RS03080 -1.0 -1.4 universal stress protein compare
MMP_RS00915 -0.9 -3.3 DUF116 domain-containing protein compare
MMP_RS01445 -0.9 -5.1 hypothetical protein compare
MMP_RS01325 -0.9 -1.4 dihydroneopterin aldolase family protein compare
MMP_RS02340 -0.9 -1.6 DNA-directed RNA polymerase subunit E'' compare
MMP_RS04485 -0.9 -4.9 putative beta-lysine N-acetyltransferase compare
MMP_RS04500 -0.9 -6.4 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS07700 -0.9 -4.7 DUF1188 domain-containing protein compare
MMP_RS01655 -0.9 -1.4 DsrE family protein compare
MMP_RS03145 -0.9 -2.9 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS07380 -0.9 -1.4 transcription elongation factor Spt5 compare
MMP_RS08605 -0.9 -2.7 flagellar protein E compare
MMP_RS07775 -0.9 -3.1 alanine dehydrogenase compare
MMP_RS05635 -0.9 -4.8 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS03700 -0.9 -3.1 sodium:proton antiporter compare
MMP_RS06015 -0.9 -2.7 flavodoxin family protein compare
MMP_RS01085 -0.9 -1.2 hypothetical protein compare
MMP_RS04955 -0.9 -1.9 DNA topoisomerase I compare
MMP_RS06475 -0.9 -2.9 FAD-dependent oxidoreductase compare
MMP_RS06020 -0.9 -1.8 archaeoflavoprotein AfpA compare
MMP_RS07390 -0.9 -1.5 cell division protein FtsZ compare
MMP_RS01955 -0.9 -1.8 hypothetical protein compare
MMP_RS00555 -0.9 -3.7 MFS transporter compare
MMP_RS02995 -0.9 -2.9 acyl-CoA thioesterase compare
MMP_RS05440 -0.8 -3.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS05965 -0.8 -1.2 carboxymuconolactone decarboxylase family protein compare
MMP_RS05100 -0.8 -5.7 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS00115 -0.8 -3.4 radical SAM protein compare
MMP_RS05075 -0.8 -5.7 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS05875 -0.8 -2.4 hydroxyethylthiazole kinase compare
MMP_RS06865 -0.8 -1.2 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS02280 -0.8 -0.5 DUF211 domain-containing protein compare
MMP_RS08195 -0.8 -3.3 hypothetical protein compare
MMP_RS01285 -0.8 -3.8 hypothetical protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress Spiramycin in Methanococcus maripaludis S2

For stress Spiramycin across organisms