Experiment set13S594 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS03475		-3.6	-0.6	hypothetical protein
MMP_RS00305		-3.2	-2.1	phosphoribosyl-ATP diphosphatase
MMP_RS01720		-2.2	-2.4	replication factor C large subunit
MMP_RS03435		-2.1	-1.3	ketol-acid reductoisomerase
MMP_RS09020		-1.7	-1.0	hypothetical protein
MMP_RS05845		-1.6	-1.2	tRNA-intron lyase
MMP_RS00515		-1.5	-0.9	DUF655 domain-containing protein
MMP_RS02280		-1.5	-0.8	DUF211 domain-containing protein
MMP_RS06885		-1.4	-1.7	50S ribosome-binding GTPase
MMP_RS06365		-1.3	-2.0	hypothetical protein
MMP_RS08435		-1.3	-1.4	Era-like GTP-binding protein
MMP_RS05835		-1.3	-0.8	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS01385		-1.3	-0.5	imidazole glycerol phosphate synthase subunit HisH
MMP_RS00900		-1.3	-1.7	50S ribosomal protein L39e
MMP_RS09025		-1.3	-1.0	hypothetical protein
MMP_RS06840		-1.3	-0.8	DNA-directed RNA polymerase subunit N
MMP_RS06870		-1.1	-2.8	DedA family protein
MMP_RS08615		-1.1	-1.6	flagellar protein G
MMP_RS01960		-1.1	-0.6	hypothetical protein
MMP_RS06230		-1.1	-1.6	helix-turn-helix domain-containing protein
MMP_RS06625		-1.1	-0.9	DNA primase
MMP_RS03785		-1.0	-3.1	cupin domain-containing protein
MMP_RS01700		-1.0	-0.6	dihydroxy-acid dehydratase
MMP_RS07435		-1.0	-1.6	GMP synthase subunit A
MMP_RS00060		-1.0	-0.8	3-dehydroquinate synthase II
MMP_RS00830		-1.0	-1.4	purine phosphoribosyltransferase family protein
MMP_RS07750		-0.9	-2.4	DUF357 domain-containing protein
MMP_RS06155		-0.9	-1.1	DUF4186 domain-containing protein
MMP_RS08725		-0.9	-1.1	Ni/Fe hydrogenase subunit alpha
MMP_RS07820		-0.9	-2.3	UPF0104 family protein
MMP_RS02490		-0.9	-1.5	hypothetical protein
MMP_RS06290		-0.9	-2.1	DNA repair and recombination protein RadA
MMP_RS05250		-0.9	-1.3	NFYB/HAP3 family transcription factor subunit
MMP_RS05355		-0.9	-0.6	hypothetical protein
MMP_RS03775		-0.9	-1.9	4Fe-4S dicluster domain-containing protein
MMP_RS01830		-0.9	-0.8	tRNA-Val
MMP_RS02790		-0.8	-0.7	class III signal peptide-containing protein
MMP_RS06940		-0.8	-1.4	polyprenyl diphosphate synthase
MMP_RS00915		-0.8	-2.6	DUF116 domain-containing protein
MMP_RS08650		-0.8	-1.2	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS02145		-0.8	-2.3	winged helix-turn-helix transcriptional regulator
MMP_RS07755		-0.8	-0.5	DUF555 domain-containing protein
MMP_RS07885		-0.8	-1.0	tripartite tricarboxylate transporter permease
MMP_RS03800		-0.7	-1.0	hypothetical protein
MMP_RS00735		-0.7	-2.3	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS08675		-0.7	-1.3	class III signal peptide-containing protein
MMP_RS04035		-0.7	-1.4	hypothetical protein
MMP_RS06120		-0.7	-1.3	UPF0147 family protein
MMP_RS07580		-0.7	-1.0	DUF356 domain-containing protein
MMP_RS03450		-0.7	-1.0	glycine synthesis protein GlyXS (from data)
MMP_RS04480		-0.7	-4.5	lysine 2 3-aminomutase
MMP_RS02265		-0.7	-1.8	nitroreductase family protein
MMP_RS01935		-0.7	-3.4	DUF58 domain-containing protein
MMP_RS01905		-0.7	-3.4	glycosyltransferase
MMP_RS00880		-0.7	-1.4	ribosome assembly RNA-binding protein YhbY
MMP_RS06395		-0.7	-1.6	ThiF family adenylyltransferase
MMP_RS05830		-0.7	-1.4	peptidyl-prolyl cis-trans isomerase
MMP_RS00040		-0.7	-2.1	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS06730		-0.6	-0.4	phosphopantothenate/pantothenate synthetase
MMP_RS08440		-0.6	-0.9	cell division protein SepF
MMP_RS00430		-0.6	-1.0	hypothetical protein
MMP_RS04485		-0.6	-2.7	putative beta-lysine N-acetyltransferase
MMP_RS00325		-0.6	-0.5	RNA-binding protein
MMP_RS08670		-0.6	-1.9	metallophosphoesterase
MMP_RS04195		-0.6	-1.1	flavodoxin
MMP_RS04060		-0.6	-2.5	hypothetical protein
MMP_RS08460		-0.6	-0.9	proteasome-activating nucleotidase
MMP_RS05640		-0.6	-1.6	UTP--glucose-1-phosphate uridylyltransferase GalU
MMP_RS04030		-0.6	-1.9	hypothetical protein
MMP_RS01675		-0.6	-0.8	hypothetical protein
MMP_RS06605		-0.6	-3.3	DUF5814 domain-containing protein
MMP_RS01435		-0.6	-1.6	DMT family transporter
MMP_RS05175		-0.6	-2.0	hypothetical protein
MMP_RS01110		-0.6	-1.4	FmdE family protein
MMP_RS01460		-0.6	-1.0	hypothetical protein
MMP_RS01925		-0.6	-2.2	DUF1616 domain-containing protein
MMP_RS00185		-0.6	-3.7	potassium channel protein
MMP_RS07925		-0.5	-1.5	haloacid dehalogenase
MMP_RS04790		-0.5	-2.4	4-hydroxy-tetrahydrodipicolinate reductase
MMP_RS04090		-0.5	-0.9	hypothetical protein
MMP_RS08240		-0.5	-1.5	methanogenesis marker 16 metalloprotein
MMP_RS03330		-0.5	-3.2	rubrerythrin family protein
MMP_RS01030		-0.5	-2.1	MTAP family purine nucleoside phosphorylase
MMP_RS07880		-0.5	-1.7	AAA family ATPase
MMP_RS00910		-0.5	-2.6	2-phosphosulfolactate phosphatase
MMP_RS04740		-0.5	-1.0	DUF473 domain-containing protein
MMP_RS00720		-0.5	-2.2	metal-dependent hydrolase
MMP_RS05420		-0.5	-2.0	DUF61 family protein
MMP_RS01885		-0.5	-1.8	Gfo/Idh/MocA family oxidoreductase
MMP_RS08580		-0.5	-1.7	flagellin
MMP_RS08390		-0.5	-0.7	DUF5400 domain-containing protein
MMP_RS07355		-0.5	-0.4	transcription factor S
MMP_RS03765		-0.5	-1.5	CopG family ribbon-helix-helix protein
MMP_RS01880		-0.5	-1.7	DegT/DnrJ/EryC1/StrS family aminotransferase
MMP_RS06015		-0.5	-2.8	flavodoxin family protein
MMP_RS05580		-0.5	-2.6	glycosyltransferase
MMP_RS06315		-0.5	-0.3	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS06270		-0.5	-1.3	TIGR00300 family protein
MMP_RS05700		-0.5	-2.6	TfuA-related McrA-glycine thioamidation protein
MMP_RS03390		-0.5	-1.7	malate dehydrogenase
MMP_RS06735		-0.5	-2.0	class I SAM-dependent rRNA methyltransferase
MMP_RS03950		-0.5	-1.7	HNH endonuclease
MMP_RS07725		-0.4	-0.8	4Fe-4S dicluster domain-containing protein
MMP_RS08175		-0.4	-1.3	7-cyano-7-deazaguanine synthase
MMP_RS08645		-0.4	-1.7	UPF0179 family protein
MMP_RS08860		-0.4	-1.4	MinD/ParA family protein
MMP_RS05360		-0.4	-0.8	hypothetical protein
MMP_RS04850		-0.4	-2.9	UPF0254 family protein
MMP_RS06670		-0.4	-0.9	glucose-6-phosphate isomerase
MMP_RS01465		-0.4	-0.9	hypothetical protein
MMP_RS01900		-0.4	-2.4	hypothetical protein
MMP_RS03560		-0.4	-2.7	Na+/H+ antiporter NhaC family protein
MMP_RS08930		-0.4	-0.6	hypothetical protein
MMP_RS02955		-0.4	-0.8	DJ-1/PfpI family protein
MMP_RS08640		-0.4	-2.5	TIM barrel protein
MMP_RS01600		-0.4	-0.9	50S ribosomal protein L15e
MMP_RS02875		-0.4	-1.4	chorismate pyruvate-lyase family protein
MMP_RS07695		-0.4	-1.4	DUF3236 domain-containing protein
MMP_RS06525		-0.4	-0.4	YciI family protein
MMP_RS03995		-0.4	-2.0	flippase-like domain-containing protein
MMP_RS05430		-0.4	-1.6	TIGR00288 family NYN domain-containing protein
MMP_RS01100		-0.4	-0.3	ABC transporter ATP-binding protein
MMP_RS03205		-0.4	-0.5	peptidyl-tRNA hydrolase Pth2
MMP_RS01640		-0.4	-2.2	2-oxoacid:acceptor oxidoreductase subunit alpha
MMP_RS04250		-0.4	-1.6	PC4/YdbC family ssDNA-binding protein
MMP_RS01005		-0.4	-0.3	riboflavin synthase
MMP_RS08385		-0.4	-1.1	ABC transporter substrate-binding protein
MMP_RS00155		-0.4	-1.4	heavy metal-binding domain-containing protein
MMP_RS03465		-0.4	-0.4	adenine phosphoribosyltransferase
MMP_RS04445		-0.4	-1.9	P-II family nitrogen regulator
MMP_RS08570		-0.4	-1.8	coenzyme F420-0:L-glutamate ligase
MMP_RS02730		-0.4	-1.8	ModD protein
MMP_RS08415		-0.4	-1.0	radical SAM protein
MMP_RS03210		-0.4	-2.3	tRNA guanosine(15) transglycosylase TgtA
MMP_RS05635		-0.4	-1.6	NAD-dependent epimerase/dehydratase family protein
MMP_RS09030		-0.4	-1.1	hypothetical protein
MMP_RS07685		-0.4	-1.3	TIGR01212 family radical SAM protein
MMP_RS08660		-0.4	-1.4	DHH family phosphoesterase
MMP_RS03490		-0.4	-0.5	DUF2115 domain-containing protein
MMP_RS07805		-0.4	-1.4	ABC transporter permease
MMP_RS02605		-0.4	-0.3	MotA/TolQ/ExbB proton channel family protein
MMP_RS08195		-0.4	-1.9	hypothetical protein
MMP_RS02410		-0.4	-0.9	ABC transporter substrate-binding protein
MMP_RS02235		-0.4	-1.7	CBS domain-containing protein
MMP_RS01620		-0.4	-0.6	hypothetical protein
MMP_RS06460		-0.4	-0.9	pyrimidine dimer DNA glycosylase/endonuclease V
MMP_RS01910		-0.4	-1.5	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
MMP_RS05435		-0.4	-1.3	5'/3'-nucleotidase SurE
MMP_RS00150		-0.4	-1.5	AAA family ATPase
MMP_RS00455		-0.4	-1.5	orotate phosphoribosyltransferase-like protein
MMP_RS00730		-0.4	-0.9	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS01490		-0.4	-1.4	tetratricopeptide repeat protein
MMP_RS00130		-0.4	-0.3	nickel-responsive transcriptional regulator NikR
MMP_RS02905		-0.4	-0.7	2-thiouracil desulfurase family protein
MMP_RS01145		-0.4	-1.5	ABC transporter ATP-binding protein
MMP_RS06035		-0.4	-1.5	glycosyltransferase family 2 protein
MMP_RS08280		-0.4	-0.5	proteasome assembly chaperone family protein
MMP_RS00110		-0.4	-0.5	hypothetical protein
MMP_RS05425		-0.4	-0.7	monovalent cation/H+ antiporter complex subunit F
MMP_RS01140		-0.3	-0.9	molybdate ABC transporter permease subunit
MMP_RS01125		-0.3	-1.5	thioredoxin family protein
MMP_RS08535		-0.3	-1.3	bis-aminopropyl spermidine synthase family protein
MMP_RS06550		-0.3	-1.4	AMP-binding protein
MMP_RS06515		-0.3	-0.6	UPF0489 family protein
MMP_RS08945		-0.3	-1.5	hypothetical protein
MMP_RS01105		-0.3	-1.3	hypothetical protein
MMP_RS03410		-0.3	-1.3	hypothetical protein
MMP_RS07895		-0.3	-0.6	cytochrome c
MMP_RS03315		-0.3	-0.2	ferrous iron transport protein A
MMP_RS01515		-0.3	-1.9	PINc/VapC family ATPase
MMP_RS01430		-0.3	-1.2	mechanosensitive ion channel family protein
MMP_RS02495		-0.3	-0.7	hypothetical protein
MMP_RS00955		-0.3	-1.7	coenzyme gamma-F420-2:alpha-L-glutamate ligase
MMP_RS05235		-0.3	-1.5	exodeoxyribonuclease III
MMP_RS06445		-0.3	-0.8	DUF89 domain-containing protein
MMP_RS04990		-0.3	-1.8	aquaporin family protein
MMP_RS05575		-0.3	-1.8	hypothetical protein
MMP_RS04490		-0.3	-1.4	CBS domain-containing protein
MMP_RS04785		-0.3	-2.0	hypothetical protein
MMP_RS03420		-0.3	-0.6	acetolactate synthase small subunit
MMP_RS07770		-0.3	-1.0	alanine racemase
MMP_RS08365		-0.3	-1.0	energy conserving hydrogenase EhbF
MMP_RS07005		-0.3	-0.1	4Fe-4S binding protein
MMP_RS06590		-0.3	-0.4	GNAT family N-acetyltransferase
MMP_RS02315		-0.3	-1.1	RimK family alpha-L-glutamate ligase
MMP_RS02010		-0.3	-1.5	PHP domain-containing protein
MMP_RS03125		-0.3	-0.9	cell division ATPase MinD
MMP_RS02170		-0.3	-1.1	CBS domain-containing protein
MMP_RS07115		-0.3	-1.4	MBL fold metallo-hydrolase
MMP_RS06975		-0.3	-0.4	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS00850		-0.3	-0.6	TIGR01177 family methyltransferase
MMP_RS08775		-0.3	-0.7	methanogenesis marker 9 domain-containing protein
MMP_RS00810		-0.3	-1.0	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS02580		-0.3	-1.0	cupin domain-containing protein
MMP_RS08785		-0.3	-0.2	RNA-protein complex protein Nop10
MMP_RS00315		-0.3	-1.3	Nif3-like dinuclear metal center hexameric protein
MMP_RS04310		-0.3	-0.6	hypothetical protein
MMP_RS05290		-0.3	-1.4	TetR/AcrR family transcriptional regulator
MMP_RS02745		-0.3	-0.6	hypothetical protein
MMP_RS06905		-0.3	-0.3	hypothetical protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Magnesium chloride hexahydrate across organisms