Experiment set13S589 for Methanococcus maripaludis S2

Compare to:

McCas_formate_complete 2,2-dibromo-2-cyanoacetamide 0.0333333333333333 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS02355 -4.4 -2.4 30S ribosomal protein S27ae compare
MMP_RS01020 -3.9 -1.2 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06730 -3.8 -2.9 phosphopantothenate/pantothenate synthetase compare
MMP_RS02340 -3.5 -4.0 DNA-directed RNA polymerase subunit E'' compare
MMP_RS08720 -3.5 -1.8 4Fe-4S binding protein compare
MMP_RS04890 -3.5 -0.9 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS06355 -3.3 -2.8 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS03155 -3.2 -7.7 precorrin-6A reductase compare
MMP_RS08070 -3.2 -7.3 DUF2096 domain-containing protein compare
MMP_RS06315 -3.2 -1.1 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08460 -3.1 -3.2 proteasome-activating nucleotidase compare
MMP_RS07635 -3.0 -9.8 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS01610 -3.0 -3.6 hypothetical protein compare
MMP_RS03960 -3.0 -1.3 hypothetical protein compare
MMP_RS06175 -3.0 -8.8 winged helix-turn-helix transcriptional regulator compare
MMP_RS01005 -2.9 -1.5 riboflavin synthase compare
MMP_RS00120 -2.9 -5.4 LysR family transcriptional regulator compare
MMP_RS03445 -2.9 -1.2 methanogenesis marker 17 protein compare
MMP_RS02900 -2.9 -0.9 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS03015 -2.9 -10.1 GTP 3' 8-cyclase MoaA compare
MMP_RS00305 -2.8 -2.0 phosphoribosyl-ATP diphosphatase compare
MMP_RS04585 -2.8 -11.9 AIR synthase related protein compare
MMP_RS02800 -2.7 -5.6 nucleotidyltransferase domain-containing protein compare
MMP_RS01175 -2.7 -3.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS00895 -2.7 -6.0 hypothetical protein compare
MMP_RS07380 -2.7 -2.7 transcription elongation factor Spt5 compare
MMP_RS02875 -2.6 -10.3 chorismate pyruvate-lyase family protein compare
MMP_RS04710 -2.6 -2.2 hypothetical protein compare
MMP_RS06120 -2.6 -3.2 UPF0147 family protein compare
MMP_RS02165 -2.6 -12.4 tRNA-dihydrouridine synthase compare
MMP_RS08945 -2.6 -11.3 hypothetical protein compare
MMP_RS02645 -2.6 -10.6 ArsR family transcriptional regulator compare
MMP_RS08635 -2.6 -2.1 UbiA family prenyltransferase compare
MMP_RS05925 -2.6 -4.4 small nuclear ribonucleoprotein compare
MMP_RS03110 -2.5 -7.1 glycosyltransferase family 2 protein compare
MMP_RS06110 -2.5 -4.6 ATP-dependent protease LonB compare
MMP_RS05920 -2.5 -0.6 50S ribosomal protein L37e compare
MMP_RS03435 -2.5 -2.2 ketol-acid reductoisomerase compare
MMP_RS01325 -2.5 -2.6 dihydroneopterin aldolase family protein compare
MMP_RS05515 -2.5 -7.4 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS05250 -2.5 -4.3 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08650 -2.5 -5.2 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01500 -2.5 -2.8 CBS domain-containing protein compare
MMP_RS06895 -2.4 -1.5 selenocysteine-specific translation elongation factor compare
MMP_RS06400 -2.4 -1.6 4Fe-4S binding protein compare
MMP_RS06020 -2.4 -4.7 archaeoflavoprotein AfpA compare
MMP_RS04870 -2.4 -6.0 TIGR02253 family HAD-type hydrolase compare
MMP_RS06295 -2.4 -7.1 methanogenesis marker 14 protein compare
MMP_RS01755 -2.4 -1.3 DUF2097 domain-containing protein compare
MMP_RS06230 -2.4 -3.1 helix-turn-helix domain-containing protein compare
MMP_RS00110 -2.3 -4.0 hypothetical protein compare
MMP_RS06975 -2.3 -2.8 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS04685 -2.3 -3.3 DUF126 domain-containing protein compare
MMP_RS05445 -2.3 -8.8 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS03035 -2.2 -3.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS03315 -2.2 -1.2 ferrous iron transport protein A compare
MMP_RS08075 -2.2 -5.4 DUF749 domain-containing protein compare
MMP_RS08300 -2.2 -1.2 metal-sulfur cluster assembly factor compare
MMP_RS05430 -2.2 -4.3 TIGR00288 family NYN domain-containing protein compare
MMP_RS08940 -2.2 -1.8 MetS family NSS transporter small subunit compare
MMP_RS02240 -2.2 -3.7 methanogenesis marker 7 protein compare
MMP_RS03600 -2.1 -2.5 triose-phosphate isomerase compare
MMP_RS01220 -2.1 -6.6 hypothetical protein compare
MMP_RS00685 -2.1 -4.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS08645 -2.1 -7.7 UPF0179 family protein compare
MMP_RS06680 -2.1 -10.0 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS01795 -2.1 -1.5 methanogenesis marker 6 protein compare
MMP_RS06350 -2.1 -6.1 HesA/MoeB/ThiF family protein compare
MMP_RS06290 -2.1 -6.6 DNA repair and recombination protein RadA compare
MMP_RS00515 -2.1 -1.2 DUF655 domain-containing protein compare
MMP_RS06345 -2.1 -9.7 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS03580 -2.1 -4.0 signal recognition particle-docking protein FtsY compare
MMP_RS07445 -2.0 -5.6 helix-turn-helix domain-containing protein compare
MMP_RS07765 -2.0 -9.3 sodium:alanine symporter family protein compare
MMP_RS08820 -2.0 -6.8 hypothetical protein compare
MMP_RS03640 -2.0 -4.4 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS07605 -2.0 -3.1 diadenylate cyclase compare
MMP_RS06715 -2.0 -13.2 cache domain-containing protein compare
MMP_RS07630 -1.9 -1.8 ATP-binding cassette domain-containing protein compare
MMP_RS03025 -1.9 -4.2 molybdenum cofactor guanylyltransferase compare
MMP_RS00695 -1.9 -1.0 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00115 -1.9 -11.1 radical SAM protein compare
MMP_RS03555 -1.9 -7.3 transcriptional regulator compare
MMP_RS07620 -1.9 -4.7 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS01650 -1.8 -1.2 sulfurtransferase TusA family protein compare
MMP_RS06725 -1.8 -7.2 hypothetical protein compare
MMP_RS06625 -1.8 -2.0 DNA primase compare
MMP_RS07525 -1.8 -7.2 4Fe-4S binding protein compare
MMP_RS04780 -1.8 -3.0 ribonuclease P compare
MMP_RS02650 -1.8 -6.6 flavodoxin family protein compare
MMP_RS00130 -1.8 -1.4 nickel-responsive transcriptional regulator NikR compare
MMP_RS06860 -1.8 -2.2 4Fe-4S binding protein compare
MMP_RS06720 -1.8 -4.5 response regulator transcription factor compare
MMP_RS08000 -1.8 -11.9 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS02235 -1.8 -7.0 CBS domain-containing protein compare
MMP_RS05865 -1.8 -2.7 hypothetical protein compare
MMP_RS01380 -1.8 -4.2 PHP domain-containing protein compare
MMP_RS06475 -1.8 -3.8 FAD-dependent oxidoreductase compare
MMP_RS05765 -1.8 -5.3 M42 family metallopeptidase compare
MMP_RS03475 -1.8 -0.6 hypothetical protein compare
MMP_RS05295 -1.7 -7.1 minichromosome maintenance protein MCM compare
MMP_RS08745 -1.7 -5.2 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS01750 -1.7 -7.8 DUF63 family protein compare
MMP_RS08210 -1.7 -1.7 phosphatidylglycerophosphatase A compare
MMP_RS06685 -1.7 -8.1 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS03305 -1.7 -5.4 winged helix-turn-helix domain-containing protein compare
MMP_RS06105 -1.6 -6.7 hydrogenase maturation peptidase HycI compare
MMP_RS02195 -1.6 -3.3 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS02345 -1.6 -4.2 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06855 -1.6 -6.5 hypothetical protein compare
MMP_RS00320 -1.6 -1.7 class I SAM-dependent methyltransferase compare
MMP_RS08715 -1.6 -1.4 formylmethanofuran dehydrogenase subunit B compare
MMP_RS01980 -1.5 -9.7 trimeric intracellular cation channel family protein compare
MMP_RS01800 -1.5 -3.0 TIGR00303 family protein compare
MMP_RS07625 -1.5 -2.6 cobalt ECF transporter T component CbiQ compare
MMP_RS07600 -1.5 -1.8 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS07615 -1.5 -4.3 energy-coupling factor ABC transporter permease compare
MMP_RS07200 -1.5 -4.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS01225 -1.5 -4.0 DUF5379 domain-containing protein compare
MMP_RS05815 -1.4 -2.2 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08370 -1.4 -0.6 cation:proton antiporter subunit C compare
MMP_RS05875 -1.4 -4.1 hydroxyethylthiazole kinase compare
MMP_RS06925 -1.4 -1.8 ribonuclease VapC4 compare
MMP_RS00290 -1.4 -5.4 hypothetical protein compare
MMP_RS06865 -1.4 -1.7 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS00945 -1.4 -1.3 PadR family transcriptional regulator compare
MMP_RS01960 -1.4 -1.0 hypothetical protein compare
MMP_RS05510 -1.4 -4.8 Rrf2 family transcriptional regulator compare
MMP_RS05095 -1.4 -5.2 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon compare
MMP_RS06200 -1.3 -7.4 M24 family metallopeptidase compare
MMP_RS06340 -1.3 -5.5 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00915 -1.3 -3.9 DUF116 domain-containing protein compare
MMP_RS08195 -1.3 -4.9 hypothetical protein compare
MMP_RS05835 -1.3 -0.9 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS02780 -1.3 -5.4 hypothetical protein compare
MMP_RS00295 -1.3 -1.8 gamma carbonic anhydrase family protein compare
MMP_RS05085 -1.3 -6.0 AAA family ATPase compare
MMP_RS05090 -1.3 -6.4 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS09020 -1.3 -1.0 hypothetical protein compare
MMP_RS05440 -1.3 -5.7 winged helix-turn-helix transcriptional regulator compare
MMP_RS04875 -1.3 -2.8 energy-converting hydrogenase B subunit P compare
MMP_RS05800 -1.2 -5.7 B12-binding domain-containing radical SAM protein compare
MMP_RS03205 -1.2 -1.1 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS05100 -1.2 -9.3 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha compare
MMP_RS01545 -1.2 -1.0 CBS domain-containing protein compare
MMP_RS05020 -1.2 -2.6 hypothetical protein compare
MMP_RS06700 -1.2 -5.9 hypothetical protein compare
MMP_RS06270 -1.2 -2.8 TIGR00300 family protein compare
MMP_RS08790 -1.2 -2.1 translation initiation factor IF-2 subunit alpha compare
MMP_RS00720 -1.2 -4.9 metal-dependent hydrolase compare
MMP_RS00050 -1.2 -4.9 AarF/UbiB family protein compare
MMP_RS01265 -1.2 -1.3 hypothetical protein compare
MMP_RS07005 -1.2 -0.5 4Fe-4S binding protein compare
MMP_RS05060 -1.2 -5.9 AAA family ATPase compare
MMP_RS06940 -1.2 -2.4 polyprenyl diphosphate synthase compare
MMP_RS00185 -1.2 -8.1 potassium channel protein compare
MMP_RS00300 -1.2 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS05545 -1.2 -5.1 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS03490 -1.2 -1.6 DUF2115 domain-containing protein compare
MMP_RS02280 -1.2 -0.8 DUF211 domain-containing protein compare
MMP_RS05450 -1.1 -2.7 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS05540 -1.1 -2.2 hypothetical protein compare
MMP_RS05850 -1.1 -2.5 Ldh family oxidoreductase compare
MMP_RS00735 -1.1 -4.0 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS05555 -1.1 -1.1 DUF4040 domain-containing protein compare
MMP_RS01790 -1.1 -3.9 restriction endonuclease compare
MMP_RS05080 -1.1 -6.8 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS05075 -1.1 -8.7 acetyl-CoA decarbonylase/synthase complex subunit gamma compare
MMP_RS07545 -1.1 -0.7 HTH domain-containing protein compare
MMP_RS02595 -1.1 -1.1 putative zinc-binding protein compare
MMP_RS05550 -1.1 -0.5 cation:proton antiporter compare
MMP_RS01335 -1.1 -1.4 prefoldin subunit beta compare
MMP_RS00310 -1.1 -6.9 CBS domain-containing protein compare
MMP_RS07425 -1.1 -3.7 GTP-binding protein compare
MMP_RS06930 -1.0 -6.7 MBL fold metallo-hydrolase compare
MMP_RS05055 -1.0 -7.5 DUF166 domain-containing protein compare
MMP_RS07820 -1.0 -3.0 UPF0104 family protein compare
MMP_RS00725 -1.0 -5.1 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS07365 -1.0 -5.9 2-phosphoglycerate kinase compare
MMP_RS08215 -1.0 -2.7 DUF483 domain-containing protein compare
MMP_RS04990 -1.0 -5.4 aquaporin family protein compare
MMP_RS00620 -1.0 -4.7 4Fe-4S binding protein compare
MMP_RS03020 -1.0 -3.0 peptidylprolyl isomerase compare
MMP_RS03700 -1.0 -4.1 sodium:proton antiporter compare
MMP_RS07775 -1.0 -3.8 alanine dehydrogenase compare
MMP_RS06710 -1.0 -3.6 selenium-binding protein compare
MMP_RS05245 -1.0 -5.4 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS06630 -1.0 -0.5 UPF0058 family protein compare
MMP_RS01075 -1.0 -1.0 hypothetical protein compare
MMP_RS05065 -1.0 -2.9 CooT family nickel-binding protein compare
MMP_RS08600 -1.0 -1.7 flagellar protein D compare
MMP_RS05845 -1.0 -1.1 tRNA-intron lyase compare
MMP_RS01665 -0.9 -2.3 DUF2111 domain-containing protein compare
MMP_RS01985 -0.9 -2.4 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS01365 -0.9 -2.1 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07730 -0.9 -1.0 pyruvate synthase subunit beta compare
MMP_RS06905 -0.9 -2.2 hypothetical protein compare
MMP_RS00985 -0.9 -2.4 CDC48 family AAA ATPase compare
MMP_RS07350 -0.9 -1.3 preprotein translocase subunit Sec61beta compare
MMP_RS00475 -0.9 -4.4 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare


Specific Phenotypes

For 4 genes in this experiment

For stress 2,2-dibromo-2-cyanoacetamide in Methanococcus maripaludis S2

For stress 2,2-dibromo-2-cyanoacetamide across organisms