Experiment set13IT081 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with Cobalt chloride hexahydrate 0.4 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4071 -3.1 -4.2 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_5111 -2.8 -2.6 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_5346 -2.5 -1.7 rRNA small subunit methyltransferase I compare
Pf6N2E2_3607 -2.5 -7.9 3'-to-5' exoribonuclease RNase R compare
Pf6N2E2_3658 -2.5 -7.4 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_4797 -2.5 -1.7 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3661 -2.4 -6.1 hypothetical protein compare
Pf6N2E2_2675 -2.3 -1.2 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_4993 -2.3 -2.6 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
Pf6N2E2_5319 -2.1 -7.2 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
Pf6N2E2_2518 -2.0 -2.9 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_5705 -2.0 -3.7 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_2835 -2.0 -3.2 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) compare
Pf6N2E2_2549 -1.9 -1.8 hypothetical protein compare
Pf6N2E2_4612 -1.9 -3.9 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_5150 -1.9 -4.3 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_199 -1.8 -3.0 hypothetical protein compare
Pf6N2E2_3240 -1.8 -1.4 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf6N2E2_4599 -1.8 -1.7 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_659 -1.7 -2.2 Transcriptional regulatory protein ompR compare
Pf6N2E2_5155 -1.7 -3.2 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_2857 -1.7 -3.3 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
Pf6N2E2_3908 -1.7 -2.5 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_5320 -1.7 -6.3 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
Pf6N2E2_2519 -1.6 -1.2 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_4162 -1.6 -2.8 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_5869 -1.6 -2.5 Helicase subunit of the DNA excision repair complex compare
Pf6N2E2_6035 -1.6 -2.5 alpha/beta hydrolase fold compare
Pf6N2E2_3569 -1.6 -1.4 hypothetical protein compare
Pf6N2E2_4153 -1.6 -3.7 Sensory box histidine kinase compare
Pf6N2E2_2129 -1.6 -3.3 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_2106 -1.6 -1.7 hypothetical protein compare
Pf6N2E2_2496 -1.5 -2.1 FIG00956575: hypothetical protein compare
Pf6N2E2_4614 -1.5 -2.6 twitching motility protein PilH compare
Pf6N2E2_48 -1.5 -2.9 FIG00955661: hypothetical protein compare
Pf6N2E2_5679 -1.5 -3.7 hypothetical protein compare
Pf6N2E2_3516 -1.5 -2.6 Probable transmembrane protein compare
Pf6N2E2_4545 -1.5 -2.1 hypothetical protein compare
Pf6N2E2_4367 -1.5 -1.4 hypothetical protein compare
Pf6N2E2_6045 -1.5 -1.7 hypothetical protein compare
Pf6N2E2_2795 -1.5 -2.1 putative exported protein compare
Pf6N2E2_2402 -1.5 -1.4 hypothetical protein compare
Pf6N2E2_4399 -1.5 -4.3 GGDEF domain/EAL domain protein compare
Pf6N2E2_1032 -1.5 -1.5 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
Pf6N2E2_5430 -1.4 -3.7 Transglycosylase, Slt family compare
Pf6N2E2_2447 -1.4 -4.8 Probable protease htpX homolog (EC 3.4.24.-) compare
Pf6N2E2_5534 -1.4 -1.9 FIG000859: hypothetical protein YebC compare
Pf6N2E2_3498 -1.4 -3.2 FIG00953349: hypothetical protein compare
Pf6N2E2_5318 -1.4 -10.7 Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-) compare
Pf6N2E2_5261 -1.4 -0.7 FIG00956983: hypothetical protein compare
Pf6N2E2_4418 -1.4 -0.7 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_241 -1.4 -1.6 hypothetical protein compare
Pf6N2E2_827 -1.4 -1.8 probable dioxygenase compare
Pf6N2E2_5321 -1.4 -6.9 Heme O synthase, protoheme IX farnesyltransferase (EC 2.5.1.-) COX10-CtaB compare
Pf6N2E2_342 -1.4 -1.4 DNA-binding response regulator compare
Pf6N2E2_282 -1.4 -1.2 GNAT family acetyltransferase YjcF compare
Pf6N2E2_446 -1.4 -4.4 Glutathione reductase (EC 1.8.1.7) compare
Pf6N2E2_1315 -1.3 -1.9 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) compare
Pf6N2E2_2258 -1.3 -5.5 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_2967 -1.3 -2.1 Cold shock protein CspA compare
Pf6N2E2_5841 -1.3 -1.2 GlcG protein compare
Pf6N2E2_4360 -1.3 -6.7 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_3847 -1.3 -2.2 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_5819 -1.3 -3.9 Protein-N(5)-glutamine methyltransferase PrmB, methylates LSU ribosomal protein L3p compare
Pf6N2E2_1168 -1.3 -2.7 Transposase compare
Pf6N2E2_1804 -1.3 -3.1 Immune-responsive protein 1 compare
Pf6N2E2_2012 -1.3 -2.2 hypothetical protein compare
Pf6N2E2_693 -1.2 -2.0 hypothetical protein compare
Pf6N2E2_1305 -1.2 -2.0 Homoprotocatechuate degradative operon repressor compare
Pf6N2E2_2791 -1.2 -1.9 FIG00954883: hypothetical protein compare
Pf6N2E2_5317 -1.2 -7.9 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) compare
Pf6N2E2_453 -1.2 -2.7 LysR family transcriptional regulator STM2281 compare
Pf6N2E2_961 -1.2 -1.8 FIG00954712: hypothetical protein compare
Pf6N2E2_5785 -1.2 -2.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4974 -1.2 -5.2 DedA protein compare
Pf6N2E2_5768 -1.2 -2.5 DNA recombination-dependent growth factor C compare
Pf6N2E2_3283 -1.2 -4.4 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Pf6N2E2_1957 -1.2 -2.5 putative inner membrane protein compare
Pf6N2E2_4369 -1.2 -0.8 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_5613 -1.2 -2.1 FIG00953674: hypothetical protein compare
Pf6N2E2_5671 -1.2 -2.0 Succinylglutamate desuccinylase (EC 3.5.1.96) compare
Pf6N2E2_2870 -1.2 -1.5 Ribonuclease BN (EC 3.1.-.-) compare
Pf6N2E2_1806 -1.2 -1.3 hypothetical protein compare
Pf6N2E2_2064 -1.2 -1.6 Cobalt-precorrin-3b C17-methyltransferase compare
Pf6N2E2_2367 -1.2 -1.5 hypothetical protein compare
Pf6N2E2_3270 -1.2 -2.9 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_6063 -1.2 -3.8 2-methylcitrate dehydratase FeS dependent (EC 4.2.1.79) compare
Pf6N2E2_2927 -1.2 -2.7 Putative signal peptide protein compare
Pf6N2E2_2386 -1.1 -1.6 Magnesium and cobalt transport protein CorA compare
Pf6N2E2_1288 -1.1 -1.5 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf6N2E2_4092 -1.1 -1.7 FIG00954395: hypothetical protein compare
Pf6N2E2_1083 -1.1 -1.4 hypothetical protein compare
Pf6N2E2_1625 -1.1 -2.0 Ferric reductase (1.6.99.14) compare
Pf6N2E2_1040 -1.1 -1.4 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_3179 -1.1 -1.7 FIG021952: putative membrane protein compare
Pf6N2E2_1173 -1.1 -1.8 hypothetical protein compare
Pf6N2E2_4083 -1.1 -2.5 hypothetical protein compare
Pf6N2E2_1211 -1.1 -1.8 Lactoylglutathione lyase compare
Pf6N2E2_563 -1.1 -5.2 Serine transporter conserved
Pf6N2E2_3321 -1.1 -2.9 Ornithine cyclodeaminase (EC 4.3.1.12) compare
Pf6N2E2_2418 -1.1 -1.8 DNA-binding response regulator, LuxR family compare
Pf6N2E2_193 -1.1 -2.1 hypothetical protein compare
Pf6N2E2_4453 -1.1 -7.2 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_5006 -1.1 -3.4 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4691 -1.1 -1.8 hypothetical protein compare
Pf6N2E2_1987 -1.1 -1.0 hypothetical protein compare
Pf6N2E2_3305 -1.1 -1.9 hypothetical protein compare
Pf6N2E2_3659 -1.1 -3.5 Protein fixF compare
Pf6N2E2_3406 -1.1 -2.6 putative ABC transporter ATP-binding protein compare
Pf6N2E2_3095 -1.1 -0.9 hypothetical protein compare
Pf6N2E2_3264 -1.1 -4.0 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_6085 -1.0 -0.8 Aha1 domain superfamily compare
Pf6N2E2_2794 -1.0 -1.7 putative membrane protein compare
Pf6N2E2_5733 -1.0 -3.7 NLP/P60 family protein compare
Pf6N2E2_5226 -1.0 -1.6 FIG00955589: hypothetical protein compare
Pf6N2E2_434 -1.0 -1.9 hypothetical protein compare
Pf6N2E2_2510 -1.0 -1.7 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_5331 -1.0 -3.0 ATPase, AFG1 family compare
Pf6N2E2_1705 -1.0 -1.3 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_942 -1.0 -1.2 Mll6465 protein compare
Pf6N2E2_2499 -1.0 -1.5 Competence protein ComEA helix-hairpin-helix region precursor compare
Pf6N2E2_5520 -1.0 -3.4 Sensory box histidine kinase compare
Pf6N2E2_3612 -1.0 -1.8 HflK protein compare
Pf6N2E2_4422 -1.0 -1.8 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
Pf6N2E2_1776 -1.0 -1.4 Chemotaxis protein CheD compare
Pf6N2E2_922 -1.0 -1.4 FIG00794167: hypothetical protein compare
Pf6N2E2_2526 -1.0 -2.3 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_2634 -1.0 -5.0 Potassium uptake protein TrkH compare
Pf6N2E2_572 -1.0 -1.6 hypothetical protein compare
Pf6N2E2_2706 -1.0 -1.7 Allophanate hydrolase 2 subunit 2 (EC 3.5.1.54) compare
Pf6N2E2_2572 -1.0 -2.2 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_2732 -1.0 -2.8 Transcriptional regulator, LysR family compare
Pf6N2E2_521 -1.0 -2.2 hypothetical protein compare
Pf6N2E2_4486 -0.9 -3.4 Glycine cleavage system H protein compare
Pf6N2E2_4680 -0.9 -2.4 HTH-type transcriptional regulator BetI compare
Pf6N2E2_4413 -0.9 -4.9 FIG004064: hypothetical protein compare
Pf6N2E2_3320 -0.9 -1.9 hypothetical protein compare
Pf6N2E2_2156 -0.9 -1.6 Putative polyketide synthase (Fragment) compare
Pf6N2E2_4708 -0.9 -1.1 hypothetical protein compare
Pf6N2E2_945 -0.9 -1.5 Transcriptional regulator, TetR family compare
Pf6N2E2_3762 -0.9 -3.1 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_1632 -0.9 -1.8 Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1) compare
Pf6N2E2_1683 -0.9 -1.9 Fe2+-dicitrate sensor, membrane component compare
Pf6N2E2_4113 -0.9 -2.0 Redox-sensing transcriptional regulator QorR compare
Pf6N2E2_817 -0.9 -4.1 Protein-glutamate methylesterase (EC 3.1.1.61) compare
Pf6N2E2_2636 -0.9 -1.2 FIG027190: Putative transmembrane protein compare
Pf6N2E2_1179 -0.9 -2.0 hypothetical protein compare
Pf6N2E2_4762 -0.9 -1.3 Biotin synthesis protein BioH compare
Pf6N2E2_1081 -0.9 -1.4 probable membrane protein YPO3302 compare
Pf6N2E2_2189 -0.9 -2.4 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_1634 -0.9 -2.4 ABC-type Fe3+-siderophore transport system, permease component compare
Pf6N2E2_1912 -0.9 -1.9 hypothetical protein compare
Pf6N2E2_924 -0.9 -1.1 Transcriptional regulator XdhR, TetR family compare
Pf6N2E2_5172 -0.9 -1.7 FOG: TPR repeat compare
Pf6N2E2_1014 -0.9 -1.1 Nitrate/nitrite transporter compare
Pf6N2E2_1249 -0.9 -1.6 Transcriptional regulator, AraC family compare
Pf6N2E2_3362 -0.9 -2.3 hypothetical protein compare
Pf6N2E2_2885 -0.9 -2.9 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_2264 -0.9 -1.8 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_1635 -0.9 -2.2 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components compare
Pf6N2E2_2207 -0.9 -2.3 cytochrome b(561) compare
Pf6N2E2_40 -0.9 -3.0 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_2121 -0.9 -1.4 hypothetical protein compare
Pf6N2E2_3792 -0.8 -3.4 Glucans biosynthesis protein G precursor compare
Pf6N2E2_4120 -0.8 -5.5 Trk system potassium uptake protein TrkA compare
Pf6N2E2_3829 -0.8 -2.1 Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state) compare
Pf6N2E2_367 -0.8 -1.7 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_3323 -0.8 -1.6 hypothetical protein compare
Pf6N2E2_622 -0.8 -1.6 BatA (Bacteroides aerotolerance operon) compare
Pf6N2E2_1043 -0.8 -2.0 Transcriptional regulator, IclR family compare
Pf6N2E2_1201 -0.8 -2.4 hypothetical protein compare
Pf6N2E2_6031 -0.8 -1.3 hypothetical protein compare
Pf6N2E2_1793 -0.8 -2.8 Inositol transport system sugar-binding protein compare
Pf6N2E2_5950 -0.8 -1.7 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_4352 -0.8 -0.5 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_3255 -0.8 -1.7 YrbA protein compare
Pf6N2E2_3638 -0.8 -2.0 hypothetical protein compare
Pf6N2E2_1463 -0.8 -1.1 Isochorismate pyruvate-lyase (EC 4.-.-.-) compare
Pf6N2E2_902 -0.8 -1.3 hypothetical protein compare
Pf6N2E2_1155 -0.8 -2.0 Cyn operon transcriptional activator compare
Pf6N2E2_3726 -0.8 -2.6 3-oxoacyl-[ACP] synthase (EC 2.3.1.41) FabV like compare
Pf6N2E2_5223 -0.8 -2.6 Molybdopterin biosynthesis protein MoeB compare
Pf6N2E2_5669 -0.8 -3.0 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_3830 -0.8 -2.3 Glutaredoxin 3 (Grx3) compare
Pf6N2E2_33 -0.8 -1.6 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_553 -0.8 -2.2 Uncharacterized protein ImpD compare
Pf6N2E2_558 -0.8 -2.4 Uncharacterized protein ImpJ/VasE compare
Pf6N2E2_2387 -0.8 -1.4 Ribonuclease E inhibitor RraA compare
Pf6N2E2_2274 -0.8 -1.2 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_238 -0.8 -1.2 hypothetical protein compare
Pf6N2E2_613 -0.8 -0.8 lipoprotein, putative compare
Pf6N2E2_1505 -0.8 -2.1 Transporter, MFS superfamily compare
Pf6N2E2_1691 -0.8 -1.1 hypothetical protein compare
Pf6N2E2_3597 -0.8 -2.2 hypothetical protein compare
Pf6N2E2_3282 -0.8 -0.7 FIG005080: Possible exported protein compare
Pf6N2E2_1636 -0.8 -2.8 Ferrichrome-iron receptor compare
Pf6N2E2_4615 -0.8 -0.9 type IV pili signal transduction protein PilI compare
Pf6N2E2_3841 -0.8 -2.3 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_5574 -0.7 -1.9 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_81 -0.7 -1.6 hypothetical protein compare


Specific Phenotypes

For 5 genes in this experiment

For stress Cobalt chloride hexahydrate in Pseudomonas fluorescens FW300-N2E2

For stress Cobalt chloride hexahydrate across organisms