Experiment set13IT019 for Klebsiella michiganensis M5al

Compare to:

Fungal_growth_media_mCAFEs_v1 with Thallium(I) acetate 0.05 mg/mL

200 most important genes:

  gene name fitness t score description  
BWI76_RS18930 -7.0 -3.5 histidinol-phosphate transaminase compare
BWI76_RS26425 -6.4 -6.3 zinc/cadmium/mercury/lead-transporting ATPase compare
BWI76_RS11965 -6.3 -3.5 orotidine-5'-phosphate decarboxylase compare
BWI76_RS04250 -6.0 -7.0 homoserine kinase compare
BWI76_RS25700 -6.0 -5.5 heavy metal-responsive transcriptional regulator compare
BWI76_RS02995 -5.7 -8.2 aspartate carbamoyltransferase compare
BWI76_RS26460 -5.5 -3.4 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS08385 -5.4 -2.1 citrate (Si)-synthase compare
BWI76_RS18955 -5.1 -3.7 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS05520 -5.1 -3.6 hypothetical protein compare
BWI76_RS16490 -5.1 -1.2 glutaredoxin compare
BWI76_RS00845 -5.1 -9.9 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS07070 -4.9 -2.7 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS18920 -4.9 -2.8 ATP phosphoribosyltransferase compare
BWI76_RS00875 -4.8 -4.7 DNA-binding transcriptional regulator FabR compare
BWI76_RS21265 -4.8 -12.2 phosphoribosylformylglycinamidine synthase compare
BWI76_RS08580 -4.8 -3.2 quinolinate synthetase compare
BWI76_RS20355 -4.7 -3.5 colicin V production protein compare
BWI76_RS25115 -4.7 -7.5 argininosuccinate synthase compare
BWI76_RS26455 -4.7 -1.6 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS18940 -4.6 -4.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS00855 -4.5 -11.7 argininosuccinate lyase compare
BWI76_RS00850 -4.5 -8.1 acetylglutamate kinase compare
BWI76_RS09760 -4.5 -2.6 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS23220 -4.5 -8.0 amino-acid N-acetyltransferase compare
BWI76_RS18925 -4.4 -5.5 histidinol dehydrogenase compare
BWI76_RS17915 -4.4 -5.7 membrane protein compare
BWI76_RS21475 -4.4 -2.5 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS11850 -4.4 -7.5 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS19375 -4.3 -1.7 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS27385 -4.3 -7.9 orotate phosphoribosyltransferase compare
BWI76_RS26000 -4.3 -7.3 aspartate aminotransferase family protein compare
BWI76_RS04675 -4.3 -5.7 3-isopropylmalate dehydrogenase compare
BWI76_RS09910 -4.3 -16.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS20390 -4.3 -3.5 erythronate-4-phosphate dehydrogenase compare
BWI76_RS22755 -4.2 -2.9 phosphoadenosine phosphosulfate reductase compare
BWI76_RS00975 -4.2 -13.2 dihydroxy-acid dehydratase compare
BWI76_RS05515 -4.2 -4.0 NADH:ubiquinone reductase (Na(+)-transporting) subunit F compare
BWI76_RS27390 -4.1 -6.5 ribonuclease PH compare
BWI76_RS23365 -4.1 -3.0 LysR family transcriptional regulator compare
BWI76_RS01110 -4.1 -6.0 TDP-fucosamine acetyltransferase compare
BWI76_RS18950 -4.1 -3.5 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00835 -4.1 -11.8 phosphoenolpyruvate carboxylase compare
BWI76_RS11840 -4.1 -4.7 tryptophan synthase subunit alpha compare
BWI76_RS01615 -4.1 -8.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS04255 -4.1 -8.6 threonine synthase compare
BWI76_RS18935 -4.0 -7.0 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS24285 -4.0 -6.8 cystathionine beta-lyase compare
BWI76_RS20350 -4.0 -5.0 amidophosphoribosyltransferase compare
BWI76_RS04160 -4.0 -2.5 phosphoserine phosphatase compare
BWI76_RS04465 -3.9 -3.9 carbamoyl-phosphate synthase small subunit compare
BWI76_RS00990 -3.9 -14.6 ketol-acid reductoisomerase compare
BWI76_RS05840 -3.9 -2.4 glutamate 5-kinase compare
BWI76_RS05495 -3.9 -8.0 NADH:ubiquinone reductase (Na(+)-transporting) subunit B compare
BWI76_RS08520 -3.9 -1.6 colicin transporter TolQ compare
BWI76_RS11845 -3.9 -1.8 tryptophan synthase subunit beta compare
BWI76_RS10990 -3.8 -1.5 dihydroorotase compare
BWI76_RS21350 -3.8 -3.2 anti-RNA polymerase sigma factor SigE compare
BWI76_RS03010 -3.7 -7.6 ornithine carbamoyltransferase compare
BWI76_RS00785 -3.7 -5.2 cystathionine gamma-synthase compare
BWI76_RS04245 -3.7 -12.6 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS01115 -3.7 -2.4 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS00805 -3.7 -5.6 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04665 -3.7 -16.6 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04685 -3.7 -10.6 putative leucine operon leader peptide compare
BWI76_RS20895 -3.7 -5.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04470 -3.6 -8.2 carbamoyl phosphate synthase large subunit compare
BWI76_RS09645 -3.6 -0.8 thioredoxin-disulfide reductase compare
BWI76_RS08535 -3.6 -1.5 translocation protein TolB compare
BWI76_RS07065 -3.6 -4.7 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS21070 -3.5 -1.4 outer membrane protein assembly factor BamB compare
BWI76_RS21660 -3.5 -1.4 antirestriction protein compare
BWI76_RS00980 -3.5 -10.0 PLP-dependent threonine dehydratase compare
BWI76_RS22760 -3.4 -6.3 sulfite reductase subunit beta compare
BWI76_RS06525 -3.4 -4.3 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS01610 -3.4 -5.5 phosphoribosylamine--glycine ligase compare
BWI76_RS05490 -3.4 -5.8 Na(+)-translocating NADH-quinone reductase subunit A compare
BWI76_RS04645 -3.4 -2.3 3-dehydroquinase compare
BWI76_RS12070 -3.4 -1.1 hypothetical protein compare
BWI76_RS04240 -3.4 -2.2 thr operon leader peptide compare
BWI76_RS04845 -3.4 -7.3 nicotinate-nucleotide pyrophosphorylase compare
BWI76_RS25335 -3.3 -1.3 stringent starvation protein A compare
BWI76_RS11860 -3.3 -6.9 anthranilate synthase component I compare
BWI76_RS04525 -3.3 -1.3 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS22765 -3.3 -9.7 sulfite reductase subunit alpha compare
BWI76_RS17910 -3.3 -6.8 hypothetical protein compare
BWI76_RS04670 -3.2 -6.7 3-isopropylmalate dehydratase large subunit compare
BWI76_RS05500 -3.2 -7.5 NADH:ubiquinone reductase (Na(+)-transporting) subunit C compare
BWI76_RS08530 -3.2 -1.1 protein TolA compare
BWI76_RS01095 -3.2 -2.0 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS04680 -3.2 -14.2 2-isopropylmalate synthase compare
BWI76_RS20380 -3.2 -0.7 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS11440 -3.2 -1.0 hypothetical protein compare
BWI76_RS01125 -3.1 -4.8 4-alpha-L-fucosyltransferase compare
BWI76_RS20965 -3.1 -3.9 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS21165 -3.1 -1.3 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS24595 -3.1 -3.0 dihydroxyacetone kinase subunit DhaK compare
BWI76_RS01655 -3.1 -7.6 homoserine O-succinyltransferase compare
BWI76_RS19770 -3.0 -1.0 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS01275 -3.0 -6.4 LysR family transcriptional regulator compare
BWI76_RS05835 -3.0 -1.4 gamma-glutamyl-phosphate reductase compare
BWI76_RS23920 -3.0 -1.5 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS06535 -2.9 -1.9 endopeptidase La compare
BWI76_RS24580 -2.9 -2.8 PTS-dependent dihydroxyacetone kinase operon transcriptional regulator DhaR compare
BWI76_RS26570 -2.9 -1.8 anion permease compare
BWI76_RS21075 -2.9 -1.1 membrane protein compare
BWI76_RS09755 -2.9 -3.1 phosphoserine transaminase compare
BWI76_RS27425 -2.8 -1.1 DNA-directed RNA polymerase subunit omega compare
BWI76_RS24340 -2.8 -5.2 two-component sensor histidine kinase compare
BWI76_RS20360 -2.8 -0.6 cell division protein DedD compare
BWI76_RS08525 -2.8 -2.2 colicin transporter compare
BWI76_RS26620 -2.8 -0.6 Fe-S biogenesis protein NfuA compare
BWI76_RS19900 -2.7 -3.3 FAD:protein FMN transferase compare
BWI76_RS20375 -2.7 -1.1 membrane protein compare
BWI76_RS05510 -2.6 -3.5 NADH:ubiquinone reductase (Na(+)-transporting) subunit E compare
BWI76_RS15825 -2.6 -0.9 hypothetical protein compare
BWI76_RS06485 -2.6 -1.1 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS23360 -2.6 -1.2 diaminopimelate decarboxylase compare
BWI76_RS04270 -2.6 -3.2 transaldolase compare
BWI76_RS09970 -2.6 -0.8 porin OmpA compare
BWI76_RS04705 -2.6 -3.2 DNA-binding transcriptional regulator FruR compare
BWI76_RS16210 -2.5 -1.4 hypothetical protein compare
BWI76_RS25645 -2.5 -4.2 shikimate dehydrogenase compare
BWI76_RS25300 -2.5 -2.3 hybrid sensor histidine kinase/response regulator compare
BWI76_RS01900 -2.5 -3.5 tRNA-dihydrouridine synthase A compare
BWI76_RS22625 -2.5 -1.2 transcriptional regulator compare
BWI76_RS05015 -2.5 -1.6 transcriptional regulator compare
BWI76_RS10935 -2.5 -3.7 glucan biosynthesis glucosyltransferase H compare
BWI76_RS15195 -2.4 -1.6 DUF4186 domain-containing protein compare
BWI76_RS13775 -2.4 -2.2 putative FMN-dependent luciferase-like monooxygenase compare
BWI76_RS19840 -2.4 -0.9 hypothetical protein compare
BWI76_RS00965 -2.4 -0.8 acetolactate synthase 2 small subunit compare
BWI76_RS26470 -2.4 -3.9 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS07465 -2.4 -0.7 TetR family transcriptional regulator compare
BWI76_RS11855 -2.3 -5.8 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS20995 -2.3 -6.3 RNA degradosome polyphosphate kinase compare
BWI76_RS22690 -2.3 -1.2 adenylyl-sulfate kinase compare
BWI76_RS26670 -2.3 -6.4 two-component sensor histidine kinase compare
BWI76_RS01210 -2.3 -0.9 tyrosine recombinase XerC compare
BWI76_RS23985 -2.3 -6.1 erythrose-4-phosphate dehydrogenase compare
BWI76_RS22805 -2.3 -6.8 GTP diphosphokinase compare
BWI76_RS15965 -2.2 -4.7 MFS transporter compare
BWI76_RS26730 -2.2 -4.6 inner membrane protein YhjD compare
BWI76_RS06530 -2.2 -3.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS26055 -2.2 -7.2 siroheme synthase compare
BWI76_RS25320 -2.2 -9.0 glutamate synthase compare
BWI76_RS22120 -2.2 -4.4 glutamate--cysteine ligase compare
BWI76_RS00345 -2.2 -3.4 protein disulfide oxidoreductase DsbA compare
BWI76_RS24900 -2.2 -1.0 DeoR family transcriptional regulator compare
BWI76_RS10700 -2.1 -3.3 XRE family transcriptional regulator compare
BWI76_RS05260 -2.1 -0.8 chaperone compare
BWI76_RS19905 -2.1 -2.5 OmpK36 porin compare
BWI76_RS19845 -2.1 -5.0 phosphatase compare
BWI76_RS10305 -2.1 -5.7 transposase compare
BWI76_RS21570 -2.1 -1.9 RnfH family protein compare
BWI76_RS23885 -2.1 -0.7 2-octaprenylphenol hydroxylase compare
BWI76_RS10480 -2.1 -7.7 amino acid ABC transporter substrate-binding protein compare
BWI76_RS24850 -2.1 -5.0 DeoR family transcriptional regulator compare
BWI76_RS05450 -2.1 -0.6 ribonuclease HI compare
BWI76_RS17975 -2.0 -4.2 tail-specific protease compare
BWI76_RS23265 -2.0 -1.1 hypothetical protein compare
BWI76_RS00400 -2.0 -0.8 glutamine synthetase compare
BWI76_RS01385 -2.0 -1.5 potassium transporter compare
BWI76_RS10530 -2.0 -2.4 GntR family transcriptional regulator with compare
BWI76_RS27450 -2.0 -5.0 ferredoxin--NADP(+) reductase compare
BWI76_RS24400 -2.0 -2.7 outer membrane channel protein TolC compare
BWI76_RS26665 -2.0 -1.7 DNA-binding response regulator compare
BWI76_RS01080 -2.0 -4.4 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase compare
BWI76_RS21370 -2.0 -0.6 ATP-dependent RNA helicase SrmB compare
BWI76_RS06370 -2.0 -3.7 phosphatidylglycerophosphatase A compare
BWI76_RS24605 -2.0 -4.4 dihydroxyacetone kinase subunit DhaM compare
BWI76_RS17980 -2.0 -3.4 RNA chaperone ProQ compare
BWI76_RS26775 -1.9 -3.8 endo-1,4-D-glucanase compare
BWI76_RS21465 -1.9 -1.7 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS17720 -1.9 -0.4 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS15110 -1.9 -3.2 putative excinuclease ABC subunit A compare
BWI76_RS10950 -1.9 -1.5 MFS transporter compare
BWI76_RS26395 -1.9 -5.3 cell division protein FtsE compare
BWI76_RS06490 -1.9 -3.1 cytochrome ubiquinol oxidase subunit I compare
BWI76_RS00960 -1.9 -4.2 acetolactate synthase 2 catalytic subunit compare
BWI76_RS01070 -1.9 -5.5 thiol reductase thioredoxin compare
BWI76_RS01135 -1.9 -3.4 lipopolysaccharide N-acetylmannosaminouronosyltransferase compare
BWI76_RS01090 -1.9 -4.0 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
BWI76_RS16955 -1.9 -0.6 hypothetical protein compare
BWI76_RS26390 -1.9 -5.4 cell division protein FtsX compare
BWI76_RS21340 -1.9 -1.7 SoxR reducing system protein RseC compare
BWI76_RS00355 -1.9 -1.4 DNA polymerase I compare
BWI76_RS14065 -1.9 -0.9 hypothetical protein compare
BWI76_RS04990 -1.8 -5.4 pantoate--beta-alanine ligase compare
BWI76_RS19010 -1.8 -1.5 polysaccharide pyruvyl transferase yvff compare
BWI76_RS00240 -1.8 -0.8 FMN-binding protein MioC compare
BWI76_RS02550 -1.8 -3.3 protease modulator HflC compare
BWI76_RS12270 -1.8 -2.5 hypothetical protein compare
BWI76_RS01280 -1.8 -8.4 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase compare
BWI76_RS15015 -1.8 -1.1 DUF2132 domain-containing protein compare
BWI76_RS21360 -1.8 -5.4 L-aspartate oxidase compare
BWI76_RS02735 -1.8 -3.1 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS06495 -1.7 -6.6 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS16965 -1.7 -1.9 murein lipoprotein compare
BWI76_RS01105 -1.7 -2.9 glucose-1-phosphate thymidylyltransferase compare


Specific Phenotypes

For 14 genes in this experiment

For stress Thallium(I) acetate in Klebsiella michiganensis M5al

For stress Thallium(I) acetate across organisms