Experiment set13H8 for Pseudomonas stutzeri RCH2

Compare to:

L-Isoleucine nitrogen source

200 most important genes:

  gene name fitness t score description  
Psest_3862 -5.0 -18.3 phosphoenolpyruvate-protein phosphotransferase compare
Psest_3648 -4.4 -12.7 anthranilate phosphoribosyltransferase compare
Psest_3649 -4.3 -12.9 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_3298 -4.3 -16.2 histidinol dehydrogenase compare
Psest_0152 -4.3 -8.7 Imidazoleglycerol-phosphate dehydratase compare
Psest_1496 -4.2 -2.0 Holliday junction DNA helicase, RuvA subunit compare
Psest_0326 -4.1 -19.2 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_0325 -4.1 -16.2 Putative threonine efflux protein compare
Psest_2591 -4.0 -5.2 3-isopropylmalate dehydratase, large subunit compare
Psest_2584 -4.0 -8.1 Phosphoribosylanthranilate isomerase compare
Psest_3647 -4.0 -10.1 Indole-3-glycerol phosphate synthase compare
Psest_3650 -4.0 -19.0 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_3932 -3.8 -9.2 nitrogen regulation protein NR(I) compare
Psest_3299 -3.8 -16.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_0153 -3.8 -14.0 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_3943 -3.8 -5.6 Phosphoribosyl-AMP cyclohydrolase compare
Psest_0062 -3.7 -16.3 tryptophan synthase, alpha subunit compare
Psest_0508 -3.6 -9.0 gamma-glutamyl phosphate reductase compare
Psest_2589 -3.5 -12.7 3-isopropylmalate dehydrogenase compare
Psest_0155 -3.3 -9.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_0313 -3.3 -9.1 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_2590 -3.2 -1.8 3-isopropylmalate dehydratase, small subunit compare
Psest_0279 -3.2 -7.0 methionine biosynthesis protein MetW compare
Psest_3864 -3.2 -15.1 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0063 -3.2 -15.4 tryptophan synthase, beta subunit compare
Psest_0191 -3.2 -1.2 PAS domain S-box compare
Psest_2579 -3.2 -6.3 amidophosphoribosyltransferase compare
Psest_0280 -3.1 -15.7 homoserine O-acetyltransferase compare
Psest_2578 -3.0 -15.1 O-succinylhomoserine sulfhydrylase compare
Psest_0450 -3.0 -11.5 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) conserved
Psest_0687 -3.0 -11.2 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_0327 -2.6 -6.7 Transcriptional regulator compare
Psest_0999 -2.6 -3.9 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_2714 -2.5 -2.9 7-cyano-7-deazaguanine reductase compare
Psest_3384 -2.4 -7.9 glutamate 5-kinase compare
Psest_3931 -2.1 -6.0 Signal transduction histidine kinase, nitrogen specific compare
Psest_3317 -2.1 -6.9 Phosphotransferase System HPr (HPr) Family compare
Psest_3518 -2.0 -1.3 Transcriptional regulators compare
Psest_3159 -2.0 -6.1 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_1013 -2.0 -2.7 phosphoribosylamine--glycine ligase compare
Psest_2027 -1.9 -11.6 ATP-dependent Clp protease ATP-binding subunit clpA compare
Psest_4287 -1.9 -7.7 Predicted glutamine amidotransferases compare
Psest_1640 -1.9 -11.3 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_1782 -1.8 -3.4 Predicted transcriptional regulators compare
Psest_3944 -1.8 -2.9 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_1474 -1.8 -2.4 phosphoribosylaminoimidazole synthetase compare
Psest_2845 -1.8 -7.8 [Protein-PII] uridylyltransferase compare
Psest_3039 -1.8 -2.1 periplasmic nitrate reductase, NapE protein compare
Psest_0442 -1.7 -3.0 ATPases of the AAA+ class compare
Psest_0417 -1.7 -2.8 Acyl-CoA dehydrogenases compare
Psest_3129 -1.7 -1.3 tyrosine recombinase XerD compare
Psest_3161 -1.7 -9.3 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family conserved
Psest_2324 -1.7 -12.4 hypothetical protein compare
Psest_1657 -1.6 -1.9 NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit compare
Psest_3042 -1.6 -1.5 Nitrate reductase cytochrome c-type subunit compare
Psest_0920 -1.5 -6.9 Transcriptional regulators conserved
Psest_3399 -1.5 -1.2 Uncharacterized protein conserved in bacteria compare
Psest_2446 -1.5 -2.5 acetyl-CoA acetyltransferases compare
Psest_1295 -1.5 -6.2 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3517 -1.5 -10.3 branched-chain ketoacid ferredoxin reductase (EC 1.2.7.7) active on 4-methyl-2-oxopentanoate, (S)-3-methyl-2-oxopentanoate, or 3-methyl-2-oxobutanoate (from data) compare
Psest_2712 -1.4 -4.9 Surface lipoprotein compare
Psest_2325 -1.4 -8.3 alpha-L-glutamate ligase-related protein compare
Psest_1311 -1.4 -8.2 Branched-chain amino acid ABC-type transport system, permease components conserved
Psest_3777 -1.4 -2.8 diguanylate cyclase (GGDEF) domain compare
Psest_1012 -1.4 -4.1 Signal transduction histidine kinase compare
Psest_0097 -1.4 -1.8 phosphonates metabolism transcriptional regulator PhnF compare
Psest_1310 -1.4 -7.2 ABC-type branched-chain amino acid transport system, permease component conserved
Psest_2158 -1.4 -10.7 alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase compare
Psest_3766 -1.4 -1.6 Uncharacterized protein conserved in bacteria compare
Psest_4405 -1.4 -2.1 hypothetical protein compare
Psest_3163 -1.4 -6.7 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_0192 -1.4 -4.4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0737 -1.3 -1.2 Cu(I)-responsive transcriptional regulator compare
Psest_0520 -1.3 -1.0 hypothetical protein compare
Psest_3338 -1.3 -1.5 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_1308 -1.3 -4.4 ABC-type branched-chain amino acid transport systems, ATPase component compare
Psest_3395 -1.3 -1.2 hypothetical protein compare
Psest_1204 -1.3 -2.1 Transcriptional regulators compare
Psest_1312 -1.3 -5.0 ABC-type branched-chain amino acid transport systems, periplasmic component compare
Psest_0919 -1.3 -1.5 Permeases of the drug/metabolite transporter (DMT) superfamily compare
Psest_3419 -1.3 -6.6 Predicted transcriptional regulators compare
Psest_3700 -1.3 -1.4 hypothetical protein compare
Psest_4196 -1.3 -3.4 Type II secretory pathway, component PulK compare
Psest_2442 -1.2 -2.0 hypothetical protein compare
Psest_3662 -1.2 -2.8 DnaJ-domain-containing proteins 1 compare
Psest_1037 -1.2 -2.0 acetolactate synthase, small subunit compare
Psest_1277 -1.2 -7.6 2-isopropylmalate synthase, yeast type compare
Psest_2953 -1.2 -2.3 Histone acetyltransferase compare
Psest_3226 -1.2 -1.1 Predicted membrane protein compare
Psest_3305 -1.2 -5.6 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_3113 -1.2 -1.4 electron transport complex, RnfABCDGE type, B subunit compare
Psest_1082 -1.2 -1.8 Enoyl-CoA hydratase/carnithine racemase compare
Psest_1518 -1.2 -2.0 tRNA_Ser_CGA compare
Psest_3162 -1.2 -6.4 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family conserved
Psest_1309 -1.2 -5.8 ABC-type branched-chain amino acid transport systems, ATPase component conserved
Psest_1313 -1.2 -2.0 Uncharacterized conserved small protein compare
Psest_2532 -1.2 -2.6 Uncharacterized protein conserved in bacteria compare
Psest_3307 -1.2 -4.9 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_1656 -1.1 -1.9 NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit compare
Psest_2067 -1.1 -1.2 ABC-type oligopeptide transport system, periplasmic component compare
Psest_3304 -1.1 -3.9 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_3114 -1.1 -6.0 electron transport complex, RnfABCDGE type, C subunit compare
Psest_0031 -1.1 -1.5 Uncharacterized conserved protein compare
Psest_1079 -1.1 -3.2 Isopropylmalate/homocitrate/citramalate synthases compare
Psest_0359 -1.1 -2.4 Transcriptional regulators compare
Psest_0952 -1.1 -2.0 Uncharacterized conserved protein compare
Psest_2088 -1.1 -1.9 Uncharacterized protein conserved in bacteria compare
Psest_2321 -1.1 -3.7 methylisocitrate lyase compare
Psest_3496 -1.1 -1.2 Predicted metal-binding protein compare
Psest_2445 -1.0 -4.1 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) compare
Psest_0357 -1.0 -1.6 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_1655 -1.0 -3.9 NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit compare
Psest_4084 -1.0 -6.9 oxaloacetate decarboxylase alpha subunit compare
Psest_2983 -1.0 -1.6 hypothetical protein compare
Psest_1920 -1.0 -0.9 Uncharacterized protein conserved in bacteria compare
Psest_4008 -1.0 -6.6 PAS domain S-box compare
Psest_0609 -1.0 -1.2 hypothetical protein compare
Psest_2293 -1.0 -1.2 hypothetical protein compare
Psest_3297 -1.0 -5.2 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_2448 -1.0 -3.5 AraC-type DNA-binding domain-containing proteins compare
Psest_0133 -0.9 -1.3 type VI secretion protein, VC_A0107 family compare
Psest_0692 -0.9 -2.2 rRNA methylase, putative, group 3 compare
Psest_1679 -0.9 -1.6 ribonuclease, Rne/Rng family compare
Psest_3306 -0.9 -3.9 conserved hypothetical integral membrane protein compare
Psest_1704 -0.9 -1.2 Dehydrogenases (flavoproteins) compare
Psest_1473 -0.9 -3.8 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_3045 -0.9 -1.7 Cold shock proteins compare
Psest_1659 -0.9 -2.5 NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit compare
Psest_0503 -0.9 -1.4 Acyl dehydratase compare
Psest_1292 -0.9 -5.2 monothiol glutaredoxin, Grx4 family compare
Psest_2561 -0.9 -1.0 hypothetical protein compare
Psest_0571 -0.9 -4.3 Transcriptional regulators compare
Psest_2405 -0.9 -2.0 NAD-dependent protein deacetylases, SIR2 family compare
Psest_4142 -0.9 -1.0 hypothetical protein compare
Psest_1601 -0.9 -1.9 Signal transduction histidine kinase compare
Psest_4363 -0.9 -4.5 ATPases involved in chromosome partitioning compare
Psest_0744 -0.9 -0.9 Uncharacterized conserved protein compare
Psest_3171 -0.9 -5.1 Predicted ATPase related to phosphate starvation-inducible protein PhoH compare
Psest_2872 -0.9 -1.0 protein RecA compare
Psest_4149 -0.8 -2.1 fagellar hook-basal body proteins compare
Psest_2810 -0.8 -3.6 5'/3'-nucleotidase SurE compare
Psest_3351 -0.8 -3.2 peptide chain release factor 3 compare
Psest_0922 -0.8 -2.5 alkylhydroperoxidase AhpD family core domain compare
Psest_0119 -0.8 -1.7 hypothetical protein compare
Psest_3670 -0.8 -5.3 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
Psest_3031 -0.8 -0.5 hypothetical protein compare
Psest_4085 -0.8 -5.5 Biotin carboxylase compare
Psest_3707 -0.8 -2.6 Transcriptional regulator compare
Psest_0367 -0.8 -1.7 Predicted branched-chain amino acid permease (azaleucine resistance) compare
Psest_1804 -0.8 -1.6 Superfamily II DNA and RNA helicases compare
Psest_3303 -0.8 -2.0 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_1006 -0.8 -3.8 dTDP-4-dehydrorhamnose reductase compare
Psest_1879 -0.8 -1.8 Trk-type K+ transport systems, membrane components compare
Psest_3828 -0.8 -1.1 zinc-binding alcohol dehydrogenase family protein compare
Psest_0536 -0.8 -3.4 thiamine-phosphate pyrophosphorylase compare
Psest_3014 -0.8 -1.5 cob(I)alamin adenosyltransferase compare
Psest_3458 -0.8 -2.0 hypothetical protein compare
Psest_3860 -0.8 -1.7 Predicted permeases compare
Psest_0547 -0.8 -1.5 Urease accessory protein UreF compare
Psest_2793 -0.8 -1.7 hypothetical protein compare
Psest_2333 -0.8 -0.8 Protein of unknown function (DUF3359). compare
Psest_1139 -0.8 -3.0 PAS domain S-box compare
Psest_2907 -0.7 -0.9 Protein of unknown function (DUF3618). compare
Psest_3301 -0.7 -1.9 Predicted transcriptional regulator, BolA superfamily compare
Psest_2809 -0.7 -1.9 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_2976 -0.7 -1.2 hypothetical protein compare
Psest_0094 -0.7 -1.3 Uncharacterized enzyme of phosphonate metabolism compare
Psest_2486 -0.7 -2.9 Uncharacterized protein, possibly involved in aromatic compounds catabolism compare
Psest_3056 -0.7 -1.9 hypothetical protein compare
Psest_0489 -0.7 -0.9 phosphoserine phosphatase SerB compare
Psest_2096 -0.7 -1.7 Domain of unknown function (DUF1883). compare
Psest_4128 -0.7 -1.0 Universal stress protein UspA and related nucleotide-binding proteins compare
Psest_2530 -0.7 -2.4 cytochrome c oxidase, cbb3-type, subunit III compare
Psest_1439 -0.7 -3.5 Transcriptional regulator compare
Psest_0511 -0.7 -0.9 rRNA large subunit m3Psi methyltransferase RlmH compare
Psest_2150 -0.7 -1.3 DNA polymerase LigD, polymerase domain compare
Psest_0154 -0.7 -2.4 Uncharacterized conserved protein compare
Psest_3215 -0.7 -1.8 1-acyl-sn-glycerol-3-phosphate acyltransferase compare
Psest_0355 -0.7 -1.0 Glycine cleavage system regulatory protein compare
Psest_3516 -0.7 -3.5 Leucine dehydrogenase (EC 1.4.1.9) (from data) compare
Psest_2447 -0.7 -1.3 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_3732 -0.7 -3.0 polyphosphate kinase 1 compare
Psest_2148 -0.7 -1.9 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_3998 -0.7 -3.6 glutamate--cysteine ligase compare
Psest_2612 -0.7 -2.3 hypothetical protein compare
Psest_0078 -0.7 -0.8 hypothetical protein compare
Psest_2053 -0.7 -1.2 Uncharacterized low-complexity proteins compare
Psest_2358 -0.7 -1.8 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_2527 -0.7 -3.4 cytochrome c oxidase, cbb3-type, subunit I compare
Psest_1772 -0.7 -1.9 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_1458 -0.7 -2.0 Uncharacterized protein conserved in bacteria compare
Psest_3934 -0.6 -2.3 rRNA methylase, putative, group 2 compare
Psest_1506 -0.6 -2.0 queuosine biosynthesis protein QueC compare
Psest_3721 -0.6 -2.8 Malic enzyme compare
Psest_1000 -0.6 -4.2 PAS domain S-box compare
Psest_3314 -0.6 -3.2 ribosomal subunit interface protein compare
Psest_1981 -0.6 -3.5 S-methyl-5-thioribose-1-phosphate isomerase compare
Psest_1960 -0.6 -1.3 Bacterial protein of unknown function (DUF903). compare
Psest_2946 -0.6 -1.7 septum site-determining protein MinD compare
Psest_2491 -0.6 -2.6 succinyl-CoA synthetase, beta subunit compare


Specific Phenotypes

For 19 genes in this experiment

For nitrogen source L-Isoleucine in Pseudomonas stutzeri RCH2

For nitrogen source L-Isoleucine across organisms