Experiment set13H7 for Pseudomonas stutzeri RCH2

Compare to:

L-Isoleucine nitrogen source

200 most important genes:

  gene name fitness t score description  
Psest_2590 -5.6 -1.6 3-isopropylmalate dehydratase, small subunit compare
Psest_3862 -5.5 -16.3 phosphoenolpyruvate-protein phosphotransferase compare
Psest_3647 -5.2 -8.4 Indole-3-glycerol phosphate synthase compare
Psest_1496 -4.3 -2.0 Holliday junction DNA helicase, RuvA subunit compare
Psest_3648 -4.3 -12.5 anthranilate phosphoribosyltransferase compare
Psest_3649 -4.3 -12.9 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0153 -4.2 -17.3 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_3650 -4.2 -16.1 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_3298 -4.1 -17.0 histidinol dehydrogenase compare
Psest_3943 -4.0 -7.2 Phosphoribosyl-AMP cyclohydrolase compare
Psest_3299 -3.9 -17.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_0155 -3.9 -7.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_2584 -3.9 -7.7 Phosphoribosylanthranilate isomerase compare
Psest_0062 -3.9 -11.7 tryptophan synthase, alpha subunit compare
Psest_0326 -3.8 -15.7 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_0325 -3.8 -16.8 Putative threonine efflux protein compare
Psest_0152 -3.6 -6.6 Imidazoleglycerol-phosphate dehydratase compare
Psest_2589 -3.5 -13.8 3-isopropylmalate dehydrogenase compare
Psest_0279 -3.5 -6.4 methionine biosynthesis protein MetW compare
Psest_0508 -3.4 -9.3 gamma-glutamyl phosphate reductase compare
Psest_0063 -3.2 -13.7 tryptophan synthase, beta subunit compare
Psest_0450 -3.1 -12.0 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) conserved
Psest_2578 -3.1 -15.9 O-succinylhomoserine sulfhydrylase compare
Psest_0280 -3.1 -14.4 homoserine O-acetyltransferase compare
Psest_3384 -3.1 -10.3 glutamate 5-kinase compare
Psest_0313 -3.1 -7.4 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_3932 -3.0 -7.3 nitrogen regulation protein NR(I) compare
Psest_3864 -3.0 -14.6 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0687 -3.0 -8.0 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_0999 -2.9 -3.9 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_2579 -2.8 -6.2 amidophosphoribosyltransferase compare
Psest_2591 -2.8 -4.8 3-isopropylmalate dehydratase, large subunit compare
Psest_0327 -2.7 -5.8 Transcriptional regulator compare
Psest_3931 -2.6 -6.2 Signal transduction histidine kinase, nitrogen specific compare
Psest_3159 -2.4 -5.4 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0191 -2.3 -1.5 PAS domain S-box compare
Psest_1013 -2.3 -2.2 phosphoribosylamine--glycine ligase compare
Psest_3317 -2.1 -6.1 Phosphotransferase System HPr (HPr) Family compare
Psest_1640 -2.0 -11.9 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_1037 -2.0 -2.7 acetolactate synthase, small subunit compare
Psest_4287 -1.9 -6.7 Predicted glutamine amidotransferases compare
Psest_1704 -1.9 -1.3 Dehydrogenases (flavoproteins) compare
Psest_2764 -1.9 -2.0 hypothetical protein compare
Psest_2845 -1.8 -8.6 [Protein-PII] uridylyltransferase compare
Psest_3129 -1.8 -1.7 tyrosine recombinase XerD compare
Psest_0919 -1.8 -3.3 Permeases of the drug/metabolite transporter (DMT) superfamily compare
Psest_3047 -1.8 -1.0 methionyl-tRNA synthetase/methionyl-tRNA synthetase C-terminal region/beta chain compare
Psest_0192 -1.7 -6.2 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0417 -1.7 -3.0 Acyl-CoA dehydrogenases compare
Psest_1313 -1.7 -1.7 Uncharacterized conserved small protein compare
Psest_2325 -1.6 -8.2 alpha-L-glutamate ligase-related protein compare
Psest_2027 -1.6 -9.3 ATP-dependent Clp protease ATP-binding subunit clpA compare
Psest_3735 -1.6 -2.2 uncharacterized domain 1 compare
Psest_2446 -1.6 -3.0 acetyl-CoA acetyltransferases compare
Psest_1474 -1.5 -2.1 phosphoribosylaminoimidazole synthetase compare
Psest_3517 -1.5 -11.3 branched-chain ketoacid ferredoxin reductase (EC 1.2.7.7) active on 4-methyl-2-oxopentanoate, (S)-3-methyl-2-oxopentanoate, or 3-methyl-2-oxobutanoate (from data) compare
Psest_4142 -1.5 -1.7 hypothetical protein compare
Psest_4082 -1.5 -4.6 hypothetical protein compare
Psest_3944 -1.5 -2.3 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_0243 -1.4 -1.5 hypothetical protein compare
Psest_2756 -1.4 -1.7 hypothetical protein compare
Psest_3161 -1.4 -7.0 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family conserved
Psest_1277 -1.4 -8.6 2-isopropylmalate synthase, yeast type compare
Psest_2324 -1.4 -10.6 hypothetical protein compare
Psest_1473 -1.4 -5.5 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_1804 -1.4 -2.1 Superfamily II DNA and RNA helicases compare
Psest_3338 -1.4 -1.9 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_1309 -1.3 -6.2 ABC-type branched-chain amino acid transport systems, ATPase component conserved
Psest_0988 -1.3 -1.6 Protein of unknown function (DUF2845). compare
Psest_4298 -1.3 -1.0 Response regulator containing a CheY-like receiver domain and a GGDEF domain compare
Psest_1308 -1.3 -5.2 ABC-type branched-chain amino acid transport systems, ATPase component compare
Psest_0759 -1.3 -1.7 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT). compare
Psest_0920 -1.3 -5.7 Transcriptional regulators conserved
Psest_2532 -1.3 -3.1 Uncharacterized protein conserved in bacteria compare
Psest_2158 -1.2 -8.9 alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase compare
Psest_2321 -1.2 -5.3 methylisocitrate lyase compare
Psest_4008 -1.2 -8.4 PAS domain S-box compare
Psest_1310 -1.2 -5.0 ABC-type branched-chain amino acid transport system, permease component conserved
Psest_3303 -1.2 -3.7 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_1292 -1.2 -6.5 monothiol glutaredoxin, Grx4 family compare
Psest_1082 -1.2 -2.2 Enoyl-CoA hydratase/carnithine racemase compare
Psest_3419 -1.2 -4.7 Predicted transcriptional regulators compare
Psest_0212 -1.2 -2.0 exodeoxyribonuclease V, gamma subunit compare
Psest_1772 -1.2 -3.1 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3767 -1.1 -3.0 tyrosine recombinase XerC compare
Psest_1661 -1.1 -1.7 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_3163 -1.1 -6.0 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_2566 -1.1 -1.1 Uncharacterized protein conserved in bacteria compare
Psest_0442 -1.1 -3.0 ATPases of the AAA+ class compare
Psest_3305 -1.1 -5.5 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_4370 -1.1 -2.6 Multisubunit Na+/H+ antiporter, MnhC subunit compare
Psest_2944 -1.1 -1.4 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_1195 -1.1 -2.7 xanthine permease compare
Psest_1312 -1.1 -4.2 ABC-type branched-chain amino acid transport systems, periplasmic component compare
Psest_1388 -1.1 -1.7 Uncharacterized protein conserved in bacteria compare
Psest_1311 -1.1 -7.0 Branched-chain amino acid ABC-type transport system, permease components conserved
Psest_2953 -1.1 -2.2 Histone acetyltransferase compare
Psest_0520 -1.1 -0.9 hypothetical protein compare
Psest_3005 -1.1 -2.3 Fructose-2,6-bisphosphatase compare
Psest_3162 -1.1 -5.9 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family conserved
Psest_3145 -1.1 -1.5 hypothetical protein compare
Psest_2712 -1.0 -3.0 Surface lipoprotein compare
Psest_1506 -1.0 -3.8 queuosine biosynthesis protein QueC compare
Psest_0717 -1.0 -6.8 Protein of unknown function (DUF1631). compare
Psest_1782 -1.0 -2.1 Predicted transcriptional regulators compare
Psest_2585 -1.0 -0.5 pseudouridylate synthase I compare
Psest_0489 -1.0 -1.0 phosphoserine phosphatase SerB compare
Psest_0526 -1.0 -3.5 hypothetical protein compare
Psest_1354 -1.0 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_3304 -1.0 -2.7 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_1167 -1.0 -1.1 hypothetical protein compare
Psest_2067 -1.0 -1.1 ABC-type oligopeptide transport system, periplasmic component compare
Psest_2448 -1.0 -3.0 AraC-type DNA-binding domain-containing proteins compare
Psest_4151 -1.0 -2.4 Flagellar hook capping protein compare
Psest_0537 -1.0 -2.0 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_1543 -1.0 -2.7 Predicted transcription regulator, contains HTH domain (MarR family) compare
Psest_1463 -1.0 -0.9 SufE protein probably involved in Fe-S center assembly compare
Psest_1643 -1.0 -1.1 hypothetical protein compare
Psest_2714 -1.0 -1.4 7-cyano-7-deazaguanine reductase compare
Psest_1242 -1.0 -1.5 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_3045 -1.0 -1.3 Cold shock proteins compare
Psest_3306 -0.9 -2.5 conserved hypothetical integral membrane protein compare
Psest_3307 -0.9 -3.1 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_0148 -0.9 -3.9 nitrate transport ATP-binding subunits C and D compare
Psest_4043 -0.9 -1.6 Site-specific recombinases, DNA invertase Pin homologs compare
Psest_2320 -0.9 -3.3 2-methylcitrate synthase/citrate synthase II compare
Psest_1183 -0.9 -2.1 hydroxyisourate hydrolase compare
Psest_3670 -0.9 -6.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
Psest_3297 -0.9 -4.6 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_1518 -0.9 -1.9 tRNA_Ser_CGA compare
Psest_3399 -0.9 -0.8 Uncharacterized protein conserved in bacteria compare
Psest_2445 -0.9 -3.4 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) compare
Psest_2288 -0.9 -2.9 trigger factor compare
Psest_1006 -0.9 -4.3 dTDP-4-dehydrorhamnose reductase compare
Psest_1079 -0.9 -2.8 Isopropylmalate/homocitrate/citramalate synthases compare
Psest_0359 -0.9 -2.1 Transcriptional regulators compare
Psest_4085 -0.9 -6.0 Biotin carboxylase compare
Psest_4170 -0.9 -1.3 Flagellar biosynthesis/type III secretory pathway protein compare
Psest_3850 -0.9 -0.6 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_1306 -0.9 -1.2 hypothetical protein compare
Psest_3810 -0.9 -0.8 orotate phosphoribosyltransferase compare
Psest_0678 -0.9 -2.0 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region compare
Psest_2437 -0.9 -2.2 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) (from data) compare
Psest_1132 -0.9 -2.6 mutator mutT protein compare
Psest_2703 -0.8 -2.3 ATPases involved in chromosome partitioning compare
Psest_1655 -0.8 -3.1 NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit compare
Psest_1505 -0.8 -1.0 Organic radical activating enzymes compare
Psest_4084 -0.8 -5.4 oxaloacetate decarboxylase alpha subunit compare
Psest_3070 -0.8 -1.8 3-oxoadipyl-CoA thiolase compare
Psest_4056 -0.8 -2.5 FMN reductase, SsuE family compare
Psest_1295 -0.8 -3.4 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3112 -0.8 -2.7 electron transport complex, RnfABCDGE type, A subunit compare
Psest_4363 -0.8 -3.6 ATPases involved in chromosome partitioning compare
Psest_3171 -0.8 -4.7 Predicted ATPase related to phosphate starvation-inducible protein PhoH compare
Psest_4209 -0.8 -1.8 Uncharacterized conserved small protein compare
Psest_4219 -0.8 -1.3 DNA polymerase I compare
Psest_4195 -0.8 -3.2 general secretion pathway protein L compare
Psest_2646 -0.8 -0.9 SOS regulatory protein LexA compare
Psest_0485 -0.8 -1.8 clan AA aspartic protease, TIGR02281 family compare
Psest_3350 -0.8 -5.3 Diaminopimelate decarboxylase compare
Psest_2557 -0.8 -1.1 Protein of unknown function (DUF2474). compare
Psest_2945 -0.8 -0.6 septum site-determining protein MinC compare
Psest_1000 -0.7 -4.8 PAS domain S-box compare
Psest_1056 -0.7 -1.5 2-isopropylmalate synthase, bacterial type compare
Psest_0182 -0.7 -3.2 glycine cleavage system H protein compare
Psest_2527 -0.7 -3.7 cytochrome c oxidase, cbb3-type, subunit I compare
Psest_3226 -0.7 -0.7 Predicted membrane protein compare
Psest_2976 -0.7 -1.2 hypothetical protein compare
Psest_4086 -0.7 -3.9 Transcriptional regulator compare
Psest_2491 -0.7 -4.0 succinyl-CoA synthetase, beta subunit compare
Psest_3351 -0.7 -3.0 peptide chain release factor 3 compare
Psest_0097 -0.7 -0.8 phosphonates metabolism transcriptional regulator PhnF compare
Psest_1439 -0.7 -3.8 Transcriptional regulator compare
Psest_4196 -0.7 -2.5 Type II secretory pathway, component PulK compare
Psest_3391 -0.7 -1.4 Uncharacterized protein conserved in bacteria compare
Psest_2369 -0.7 -1.8 Transcriptional regulator compare
Psest_0385 -0.7 -1.6 Conserved secreted protein compare
Psest_0571 -0.7 -3.0 Transcriptional regulators compare
Psest_1147 -0.7 -1.9 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_0536 -0.7 -2.3 thiamine-phosphate pyrophosphorylase compare
Psest_2940 -0.7 -1.7 Predicted membrane protein compare
Psest_3998 -0.7 -3.2 glutamate--cysteine ligase compare
Psest_4282 -0.7 -3.8 spermidine/putrescine ABC transporter ATP-binding subunit compare
Psest_1238 -0.7 -3.6 Predicted membrane protein/domain compare
Psest_3043 -0.7 -2.9 periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family compare
Psest_2425 -0.7 -2.0 Trk-type K+ transport systems, membrane components compare
Psest_1065 -0.7 -1.8 hypothetical protein compare
Psest_0795 -0.7 -1.9 ABC-type multidrug transport system, ATPase component compare
Psest_4199 -0.7 -2.9 general secretion pathway protein H compare
Psest_0744 -0.7 -0.8 Uncharacterized conserved protein compare
Psest_1805 -0.7 -1.3 integration host factor, beta subunit compare
Psest_3449 -0.7 -1.2 DJ-1 family protein compare
Psest_1792 -0.7 -2.1 RND family efflux transporter, MFP subunit compare
Psest_4366 -0.7 -2.5 Multisubunit Na+/H+ antiporter, MnhG subunit compare
Psest_3389 -0.7 -1.5 hypothetical protein compare
Psest_0159 -0.7 -2.7 Uncharacterized protein conserved in bacteria compare
Psest_1994 -0.7 -2.1 Amidases related to nicotinamidase compare
Psest_4310 -0.7 -0.7 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_3355 -0.7 -2.5 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components (from data) compare
Psest_1149 -0.7 -2.0 Protein affecting phage T7 exclusion by the F plasmid compare


Specific Phenotypes

For 15 genes in this experiment

For nitrogen source L-Isoleucine in Pseudomonas stutzeri RCH2

For nitrogen source L-Isoleucine across organisms