Experiment set13H5 for Pseudomonas stutzeri RCH2

Compare to:

L-Valine nitrogen source

200 most important genes:

  gene name fitness t score description  
Psest_3862 -5.3 -14.1 phosphoenolpyruvate-protein phosphotransferase compare
Psest_2590 -5.3 -1.5 3-isopropylmalate dehydratase, small subunit compare
Psest_0153 -5.1 -12.3 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_2578 -5.0 -14.7 O-succinylhomoserine sulfhydrylase compare
Psest_1082 -4.8 -3.1 Enoyl-CoA hydratase/carnithine racemase compare
Psest_2591 -4.1 -4.3 3-isopropylmalate dehydratase, large subunit compare
Psest_0508 -4.0 -11.7 gamma-glutamyl phosphate reductase compare
Psest_3932 -3.9 -7.0 nitrogen regulation protein NR(I) compare
Psest_3649 -3.9 -11.8 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_3384 -3.8 -11.0 glutamate 5-kinase compare
Psest_0155 -3.8 -7.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_1079 -3.7 -4.4 Isopropylmalate/homocitrate/citramalate synthases compare
Psest_3648 -3.7 -11.5 anthranilate phosphoribosyltransferase compare
Psest_0062 -3.7 -13.0 tryptophan synthase, alpha subunit compare
Psest_3864 -3.7 -9.9 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_3866 -3.6 -20.3 threonine ammonia-lyase, biosynthetic, long form compare
Psest_0279 -3.6 -6.5 methionine biosynthesis protein MetW compare
Psest_1292 -3.6 -9.2 monothiol glutaredoxin, Grx4 family compare
Psest_2584 -3.6 -9.8 Phosphoribosylanthranilate isomerase compare
Psest_3298 -3.6 -11.8 histidinol dehydrogenase compare
Psest_3647 -3.6 -9.4 Indole-3-glycerol phosphate synthase compare
Psest_0313 -3.5 -7.1 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_0326 -3.5 -15.7 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_3650 -3.5 -17.0 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0280 -3.4 -13.9 homoserine O-acetyltransferase compare
Psest_3998 -3.3 -8.3 glutamate--cysteine ligase compare
Psest_2589 -3.2 -10.9 3-isopropylmalate dehydrogenase compare
Psest_0152 -3.2 -5.9 Imidazoleglycerol-phosphate dehydratase compare
Psest_0325 -3.2 -13.2 Putative threonine efflux protein compare
Psest_0063 -3.1 -11.2 tryptophan synthase, beta subunit compare
Psest_2845 -3.1 -13.0 [Protein-PII] uridylyltransferase compare
Psest_3299 -3.0 -15.1 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_0327 -3.0 -8.6 Transcriptional regulator compare
Psest_2579 -3.0 -3.5 amidophosphoribosyltransferase compare
Psest_1080 -3.0 -11.8 Acetyl/propionyl-CoA carboxylase, alpha subunit compare
Psest_1083 -2.9 -11.3 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) compare
Psest_1037 -2.9 -3.9 acetolactate synthase, small subunit compare
Psest_3517 -2.6 -16.4 branched-chain ketoacid ferredoxin reductase (EC 1.2.7.7) active on 4-methyl-2-oxopentanoate, (S)-3-methyl-2-oxopentanoate, or 3-methyl-2-oxobutanoate (from data) conserved
Psest_1295 -2.6 -8.0 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_4287 -2.5 -6.2 Predicted glutamine amidotransferases compare
Psest_3943 -2.4 -4.0 Phosphoribosyl-AMP cyclohydrolase compare
Psest_2850 -2.4 -1.7 Multisubunit Na+/H+ antiporter, MnhC subunit compare
Psest_3931 -2.4 -4.2 Signal transduction histidine kinase, nitrogen specific compare
Psest_3818 -2.3 -6.1 endoribonuclease L-PSP, putative compare
Psest_3518 -2.3 -1.3 Transcriptional regulators compare
Psest_0296 -2.3 -7.9 glutathione synthetase, prokaryotic compare
Psest_0999 -2.3 -3.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_1496 -2.2 -1.4 Holliday junction DNA helicase, RuvA subunit compare
Psest_1920 -2.2 -1.3 Uncharacterized protein conserved in bacteria compare
Psest_2090 -2.1 -3.7 Protein of unknown function (DUF2970). compare
Psest_3226 -2.1 -1.3 Predicted membrane protein compare
Psest_2988 -2.0 -6.6 aspartate kinase, monofunctional class compare
Psest_1463 -2.0 -1.3 SufE protein probably involved in Fe-S center assembly compare
Psest_4084 -2.0 -11.4 oxaloacetate decarboxylase alpha subunit compare
Psest_4085 -1.9 -11.5 Biotin carboxylase compare
Psest_2872 -1.9 -2.1 protein RecA compare
Psest_0687 -1.9 -7.9 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_0212 -1.9 -2.2 exodeoxyribonuclease V, gamma subunit compare
Psest_2158 -1.9 -13.6 alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase compare
Psest_3039 -1.8 -1.7 periplasmic nitrate reductase, NapE protein compare
Psest_3944 -1.8 -4.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_3828 -1.8 -1.3 zinc-binding alcohol dehydrogenase family protein compare
Psest_1013 -1.8 -1.2 phosphoribosylamine--glycine ligase compare
Psest_2324 -1.8 -13.0 hypothetical protein compare
Psest_0722 -1.7 -6.7 Predicted ATPase compare
Psest_2088 -1.7 -2.3 Uncharacterized protein conserved in bacteria compare
Psest_1640 -1.7 -9.6 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_3884 -1.6 -1.2 Signal transduction histidine kinase compare
Psest_2438 -1.6 -7.0 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) compare
Psest_3721 -1.6 -7.0 Malic enzyme compare
Psest_0744 -1.6 -1.2 Uncharacterized conserved protein compare
Psest_0119 -1.6 -1.8 hypothetical protein compare
Psest_1084 -1.6 -9.2 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) (from data) compare
Psest_2104 -1.6 -2.0 IscR-regulated protein YhgI compare
Psest_3297 -1.5 -7.6 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_2325 -1.5 -7.0 alpha-L-glutamate ligase-related protein compare
Psest_2436 -1.5 -6.3 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data) compare
Psest_2329 -1.5 -9.1 Transcriptional regulator compare
Psest_2440 -1.5 -5.5 isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data) conserved
Psest_1139 -1.5 -4.2 PAS domain S-box compare
Psest_3419 -1.4 -6.2 Predicted transcriptional regulators compare
Psest_3400 -1.4 -1.1 Copper resistance protein D. compare
Psest_3803 -1.4 -1.1 DNA repair protein radc compare
Psest_0953 -1.4 -6.3 iron-sulfur cluster-binding protein compare
Psest_2435 -1.4 -5.1 Transcriptional regulator conserved
Psest_1474 -1.4 -1.6 phosphoribosylaminoimidazole synthetase compare
Psest_3735 -1.4 -2.0 uncharacterized domain 1 compare
Psest_1619 -1.4 -5.5 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 compare
Psest_3159 -1.3 -4.9 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_3962 -1.3 -1.7 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED compare
Psest_0954 -1.3 -4.5 Fe-S oxidoreductase compare
Psest_0138 -1.3 -5.3 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_1111 -1.3 -3.9 Flp pilus assembly protein TadD, contains TPR repeats compare
Psest_1235 -1.3 -4.3 Leucyl aminopeptidase compare
Psest_0139 -1.3 -4.0 ABC-type histidine transport system, ATPase component compare
Psest_3301 -1.3 -3.5 Predicted transcriptional regulator, BolA superfamily compare
Psest_2439 -1.3 -6.8 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) conserved
Psest_2680 -1.3 -3.9 transcriptional regulator, BolA protein family compare
Psest_1464 -1.3 -5.5 Selenocysteine lyase compare
Psest_4158 -1.2 -1.4 Flagellar motor protein compare
Psest_2446 -1.2 -2.1 acetyl-CoA acetyltransferases compare
Psest_0442 -1.2 -2.3 ATPases of the AAA+ class compare
Psest_1118 -1.2 -2.1 Predicted Fe-S-cluster oxidoreductase compare
Psest_3537 -1.2 -4.9 hypothetical protein compare
Psest_0571 -1.2 -5.2 Transcriptional regulators compare
Psest_2907 -1.2 -1.2 Protein of unknown function (DUF3618). compare
Psest_1402 -1.2 -6.5 Putative threonine efflux protein compare
Psest_3777 -1.2 -3.7 diguanylate cyclase (GGDEF) domain compare
Psest_3795 -1.2 -5.8 Glycine/D-amino acid oxidases (deaminating) compare
Psest_3993 -1.2 -6.2 alpha-L-glutamate ligases, RimK family compare
Psest_2067 -1.1 -1.1 ABC-type oligopeptide transport system, periplasmic component compare
Psest_3816 -1.1 -0.9 DNA-directed RNA polymerase, omega subunit compare
Psest_2806 -1.1 -4.7 RNA polymerase sigma factor RpoS compare
Psest_0137 -1.1 -5.1 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_4086 -1.1 -4.8 Transcriptional regulator compare
Psest_2953 -1.1 -2.2 Histone acetyltransferase compare
Psest_2437 -1.1 -2.1 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) (from data) conserved
Psest_4219 -1.1 -1.9 DNA polymerase I compare
Psest_4083 -1.1 -7.0 Predicted permease compare
Psest_0078 -1.1 -1.1 hypothetical protein compare
Psest_0175 -1.1 -4.0 Xaa-Pro aminopeptidase compare
Psest_3840 -1.1 -3.4 D-lactate/glycolate dehydrogenase, FAD binding subunit GlcE (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_1081 -1.0 -2.1 hypothetical protein compare
Psest_0558 -1.0 -0.7 urease, beta subunit compare
Psest_0097 -1.0 -1.9 phosphonates metabolism transcriptional regulator PhnF compare
Psest_2756 -1.0 -1.1 hypothetical protein compare
Psest_3766 -1.0 -2.0 Uncharacterized protein conserved in bacteria compare
Psest_1468 -1.0 -1.9 hypothetical protein compare
Psest_1700 -1.0 -2.4 Transcriptional regulator compare
Psest_3921 -1.0 -1.8 Uncharacterized protein conserved in bacteria compare
Psest_1366 -1.0 -1.5 hypothetical protein compare
Psest_1986 -1.0 -1.0 3-phosphoshikimate 1-carboxyvinyltransferase compare
Psest_2585 -1.0 -0.7 pseudouridylate synthase I compare
Psest_2123 -1.0 -1.8 fusion of gluconokinase (EC 2.7.1.12) and the small permease component of the D-gluconate TRAP transporter (from data) compare
Psest_0136 -1.0 -5.9 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_3317 -1.0 -3.8 Phosphotransferase System HPr (HPr) Family compare
Psest_0450 -0.9 -3.7 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) compare
Psest_3670 -0.9 -5.7 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
Psest_0551 -0.9 -4.3 PEP phosphonomutase and related enzymes compare
Psest_3231 -0.9 -1.9 hypothetical protein compare
Psest_3960 -0.9 -0.9 3'(2'),5'-bisphosphate nucleotidase, bacterial compare
Psest_2018 -0.9 -2.1 Uncharacterized conserved protein compare
Psest_0510 -0.9 -2.5 iojap-like ribosome-associated protein compare
Psest_1631 -0.9 -1.3 Uncharacterized conserved small protein compare
Psest_3001 -0.9 -2.9 molybdenum ABC transporter, ATP-binding protein compare
Psest_2382 -0.9 -5.3 coenzyme PQQ biosynthesis probable peptidase PqqF compare
Psest_0115 -0.9 -1.0 Predicted integral membrane protein compare
Psest_2855 -0.9 -1.2 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Psest_1006 -0.9 -4.3 dTDP-4-dehydrorhamnose reductase compare
Psest_1403 -0.9 -3.8 Transcriptional regulators compare
Psest_3314 -0.9 -3.5 ribosomal subunit interface protein compare
Psest_3743 -0.9 -4.3 Regulator of sigma D compare
Psest_2322 -0.9 -2.0 Transcriptional regulators compare
Psest_2612 -0.9 -1.9 hypothetical protein compare
Psest_4305 -0.9 -3.5 NAD-dependent aldehyde dehydrogenases compare
Psest_2712 -0.9 -2.2 Surface lipoprotein compare
Psest_0148 -0.9 -1.9 nitrate transport ATP-binding subunits C and D compare
Psest_1704 -0.9 -0.8 Dehydrogenases (flavoproteins) compare
Psest_3168 -0.9 -1.8 Molybdopterin converting factor, large subunit compare
Psest_3480 -0.9 -1.3 molybdenum cofactor biosynthesis protein B, proteobacterial compare
Psest_3522 -0.9 -2.1 3-hydroxybutyrate dehydrogenase compare
Psest_1736 -0.9 -2.8 Cu/Zn superoxide dismutase compare
Psest_0837 -0.9 -1.6 Putative lipid carrier protein compare
Psest_0504 -0.9 -2.2 Putative effector of murein hydrolase LrgA compare
Psest_1724 -0.8 -2.0 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_0144 -0.8 -4.0 Fe-S cluster protector protein compare
Psest_3042 -0.8 -0.9 Nitrate reductase cytochrome c-type subunit compare
Psest_2253 -0.8 -1.3 small redox-active disulfide protein 2 compare
Psest_2044 -0.8 -2.0 ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system compare
Psest_0737 -0.8 -0.8 Cu(I)-responsive transcriptional regulator compare
Psest_3307 -0.8 -3.5 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_4221 -0.8 -1.7 homoserine kinase, Neisseria type compare
Psest_4005 -0.8 -2.6 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB compare
Psest_3839 -0.8 -2.0 D-lactate/glycolate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_1574 -0.8 -1.3 phenazine biosynthesis protein PhzF family compare
Psest_0145 -0.8 -1.9 A/G-specific adenine glycosylase compare
Psest_3171 -0.8 -5.1 Predicted ATPase related to phosphate starvation-inducible protein PhoH compare
Psest_1643 -0.8 -0.9 hypothetical protein compare
Psest_2557 -0.8 -1.6 Protein of unknown function (DUF2474). compare
Psest_4168 -0.8 -2.5 Flagellar FliJ protein. compare
Psest_2288 -0.8 -1.9 trigger factor compare
Psest_3519 -0.8 -1.7 Uncharacterized conserved protein compare
Psest_0066 -0.8 -1.3 Protein of unknown function (DUF3060). compare
Psest_1183 -0.8 -2.2 hydroxyisourate hydrolase compare
Psest_2027 -0.8 -4.7 ATP-dependent Clp protease ATP-binding subunit clpA compare
Psest_0503 -0.8 -1.3 Acyl dehydratase compare
Psest_2321 -0.8 -3.5 methylisocitrate lyase compare
Psest_1067 -0.8 -2.1 hypothetical protein compare
Psest_1664 -0.8 -3.6 Glycerophosphoryl diester phosphodiesterase compare
Psest_0531 -0.7 -3.7 Phosphate starvation-inducible protein PhoH, predicted ATPase compare
Psest_1354 -0.7 -0.9 Uncharacterized protein conserved in bacteria compare
Psest_2094 -0.7 -3.5 Predicted Fe-S-cluster redox enzyme compare
Psest_3700 -0.7 -0.9 hypothetical protein compare
Psest_1125 -0.7 -2.3 Protein of unknown function (DUF3509). compare
Psest_0091 -0.7 -2.9 phosphonate C-P lyase system protein PhnL compare
Psest_3575 -0.7 -3.4 Arabinose efflux permease compare
Psest_2500 -0.7 -1.6 hypothetical protein compare
Psest_0343 -0.7 -4.4 hypothetical membrane protein, TIGR01666 compare
Psest_0041 -0.7 -1.8 Uncharacterized protein conserved in bacteria compare
Psest_0154 -0.7 -2.4 Uncharacterized conserved protein compare


Specific Phenotypes

For 23 genes in this experiment

For nitrogen source L-Valine in Pseudomonas stutzeri RCH2

For nitrogen source L-Valine across organisms