Experiment set12S376 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS01385		-5.3	-0.9	imidazole glycerol phosphate synthase subunit HisH
MMP_RS05550		-2.7	-1.1	cation:proton antiporter
MMP_RS06315		-2.5	-1.2	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS07390		-2.0	-1.9	cell division protein FtsZ
MMP_RS03300		-1.8	-1.0	TOBE domain-containing protein
MMP_RS01960		-1.8	-1.6	hypothetical protein
MMP_RS03475		-1.7	-0.9	hypothetical protein
MMP_RS05835		-1.7	-1.1	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS00300		-1.6	-0.9	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS07860		-1.5	-0.8	hypothetical protein
MMP_RS01020		-1.5	-1.3	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS07730		-1.4	-2.7	pyruvate synthase subunit beta
MMP_RS08785		-1.4	-1.1	RNA-protein complex protein Nop10
MMP_RS02470		-1.4	-1.6	helix-turn-helix transcriptional regulator
MMP_RS03435		-1.4	-1.8	ketol-acid reductoisomerase
MMP_RS01755		-1.3	-1.5	DUF2097 domain-containing protein
MMP_RS03520		-1.3	-1.3	YwbE family protein
MMP_RS01240		-1.2	-1.2	7-cyano-7-deazaguanine synthase QueC
MMP_RS05425		-1.2	-4.0	monovalent cation/H+ antiporter complex subunit F
MMP_RS08435		-1.1	-1.9	Era-like GTP-binding protein
MMP_RS07845		-1.1	-3.1	LL-diaminopimelate aminotransferase
MMP_RS06285		-1.0	-1.2	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS03445		-1.0	-0.9	methanogenesis marker 17 protein
MMP_RS03080		-1.0	-2.1	universal stress protein
MMP_RS02605		-1.0	-0.7	MotA/TolQ/ExbB proton channel family protein
MMP_RS04605		-1.0	-2.7	cobalt ECF transporter T component CbiQ
MMP_RS01500		-0.9	-1.2	CBS domain-containing protein
MMP_RS03025		-0.9	-3.0	molybdenum cofactor guanylyltransferase
MMP_RS05535		-0.9	-3.0	hypothetical protein
MMP_RS01195		-0.9	-1.1	metalloregulator ArsR/SmtB family transcription factor
MMP_RS03250		-0.9	-2.4	MJ1244 family protein
MMP_RS05965		-0.9	-3.4	carboxymuconolactone decarboxylase family protein
MMP_RS05460		-0.9	-5.0	YcaO-related McrA-glycine thioamidation protein
MMP_RS00695		-0.9	-0.8	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS07545		-0.9	-0.9	HTH domain-containing protein
MMP_RS01380		-0.8	-2.7	PHP domain-containing protein
MMP_RS07420		-0.8	-2.4	metalloregulator ArsR/SmtB family transcription factor
MMP_RS08195		-0.8	-4.5	hypothetical protein
MMP_RS06355		-0.8	-2.5	molybdenum cofactor biosynthesis protein MoaE
MMP_RS06555		-0.8	-1.3	cupin domain-containing protein
MMP_RS03110		-0.8	-2.6	glycosyltransferase family 2 protein
MMP_RS00750		-0.8	-1.6	fumarate hydratase
MMP_RS08745		-0.8	-2.8	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS07635		-0.8	-3.5	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS01265		-0.8	-2.7	hypothetical protein
MMP_RS06105		-0.8	-3.5	hydrogenase maturation peptidase HycI
MMP_RS01175		-0.8	-3.2	triphosphoribosyl-dephospho-CoA synthase
MMP_RS07625		-0.8	-1.5	cobalt ECF transporter T component CbiQ
MMP_RS06840		-0.8	-0.9	DNA-directed RNA polymerase subunit N
MMP_RS05280		-0.7	-3.7	COG1361 S-layer family protein
MMP_RS05910		-0.7	-1.3	cell division ATPase MinD
MMP_RS04485		-0.7	-4.0	putative beta-lysine N-acetyltransferase
MMP_RS02145		-0.7	-3.0	winged helix-turn-helix transcriptional regulator
MMP_RS01795		-0.7	-0.9	methanogenesis marker 6 protein
MMP_RS05515		-0.7	-3.4	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS06915		-0.7	-2.5	metallophosphoesterase
MMP_RS06900		-0.7	-1.4	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS08600		-0.7	-0.8	flagellar protein D
MMP_RS00305		-0.7	-1.0	phosphoribosyl-ATP diphosphatase
MMP_RS06350		-0.7	-2.5	HesA/MoeB/ThiF family protein
MMP_RS06175		-0.7	-3.8	winged helix-turn-helix transcriptional regulator
MMP_RS01100		-0.7	-0.9	ABC transporter ATP-binding protein
MMP_RS01545		-0.6	-0.8	CBS domain-containing protein
MMP_RS03700		-0.6	-2.9	sodium:proton antiporter
MMP_RS07180		-0.6	-3.9	DEAD/DEAH box helicase
MMP_RS04900		-0.6	-5.6	hypothetical protein
MMP_RS09020		-0.6	-0.8	hypothetical protein
MMP_RS05640		-0.6	-2.0	UTP--glucose-1-phosphate uridylyltransferase GalU
MMP_RS06295		-0.6	-3.0	methanogenesis marker 14 protein
MMP_RS04870		-0.6	-2.5	TIGR02253 family HAD-type hydrolase
MMP_RS04720		-0.6	-1.1	DedA family protein
MMP_RS07350		-0.6	-0.8	preprotein translocase subunit Sec61beta
MMP_RS02800		-0.6	-3.3	nucleotidyltransferase domain-containing protein
MMP_RS01925		-0.6	-3.2	DUF1616 domain-containing protein
MMP_RS02135		-0.6	-1.6	DUF5612 domain-containing protein
MMP_RS01765		-0.6	-1.7	HIT family protein
MMP_RS08820		-0.6	-2.4	hypothetical protein
MMP_RS06895		-0.6	-0.7	selenocysteine-specific translation elongation factor
MMP_RS02010		-0.6	-2.4	PHP domain-containing protein
MMP_RS06630		-0.6	-0.5	UPF0058 family protein
MMP_RS05285		-0.5	-2.5	MMPL family transporter
MMP_RS01575		-0.5	-2.6	aldolase
MMP_RS01720		-0.5	-0.8	replication factor C large subunit
MMP_RS08860		-0.5	-1.8	MinD/ParA family protein
MMP_RS02240		-0.5	-1.1	methanogenesis marker 7 protein
MMP_RS03390		-0.5	-2.0	malate dehydrogenase
MMP_RS06765		-0.5	-1.9	flap endonuclease-1
MMP_RS01665		-0.5	-1.3	DUF2111 domain-containing protein
MMP_RS00515		-0.5	-0.6	DUF655 domain-containing protein
MMP_RS01900		-0.5	-3.3	hypothetical protein
MMP_RS00320		-0.5	-0.9	class I SAM-dependent methyltransferase
MMP_RS06535		-0.5	-1.7	2-oxoacid:acceptor oxidoreductase family protein
MMP_RS08105		-0.5	-1.9	6-carboxyhexanoate--CoA ligase
MMP_RS08650		-0.5	-1.1	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS08675		-0.5	-1.6	class III signal peptide-containing protein
MMP_RS04710		-0.5	-0.8	hypothetical protein
MMP_RS01965		-0.5	-1.2	DUF1616 domain-containing protein
MMP_RS05930		-0.5	-0.8	3-isopropylmalate dehydratase large subunit
MMP_RS08175		-0.5	-1.6	7-cyano-7-deazaguanine synthase
MMP_RS04035		-0.5	-0.9	hypothetical protein
MMP_RS03315		-0.5	-0.4	ferrous iron transport protein A
MMP_RS03015		-0.5	-2.7	GTP 3' 8-cyclase MoaA
MMP_RS00240		-0.5	-3.7	type II secretion system F family protein
MMP_RS07755		-0.5	-0.5	DUF555 domain-containing protein
MMP_RS01905		-0.5	-3.1	glycosyltransferase
MMP_RS05355		-0.5	-0.4	hypothetical protein
MMP_RS01305		-0.5	-3.8	hypothetical protein
MMP_RS08280		-0.5	-1.4	proteasome assembly chaperone family protein
MMP_RS01610		-0.5	-1.1	hypothetical protein
MMP_RS05420		-0.5	-2.0	DUF61 family protein
MMP_RS06925		-0.5	-0.8	ribonuclease VapC4
MMP_RS03580		-0.5	-1.3	signal recognition particle-docking protein FtsY
MMP_RS07775		-0.4	-1.4	alanine dehydrogenase
MMP_RS04695		-0.4	-2.0	selenide water dikinase SelD
MMP_RS05510		-0.4	-1.6	Rrf2 family transcriptional regulator
MMP_RS02545		-0.4	-1.5	hypothetical protein
MMP_RS03640		-0.4	-1.4	archaeal proteasome endopeptidase complex subunit beta
MMP_RS00060		-0.4	-0.8	3-dehydroquinate synthase II
MMP_RS07345		-0.4	-1.5	glycine synthesis protein GlyXL (from data)
MMP_RS06600		-0.4	-0.5	class III signal peptide-containing protein
MMP_RS00720		-0.4	-2.0	metal-dependent hydrolase
MMP_RS01310		-0.4	-3.2	hypothetical protein
MMP_RS09055		-0.4	-0.5	CAP domain-containing protein
MMP_RS01990		-0.4	-1.8	hypothetical protein
MMP_RS03590		-0.4	-2.1	METTL5 family protein
MMP_RS03420		-0.4	-1.1	acetolactate synthase small subunit
MMP_RS06340		-0.4	-1.9	phosphoadenosine phosphosulfate reductase family protein
MMP_RS02340		-0.4	-0.7	DNA-directed RNA polymerase subunit E''
MMP_RS05295		-0.4	-2.5	minichromosome maintenance protein MCM
MMP_RS07580		-0.4	-1.3	DUF356 domain-containing protein
MMP_RS05540		-0.4	-1.4	hypothetical protein
MMP_RS04480		-0.4	-3.1	lysine 2 3-aminomutase
MMP_RS06720		-0.4	-2.4	response regulator transcription factor
MMP_RS07355		-0.4	-0.4	transcription factor S
MMP_RS00730		-0.4	-1.8	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS02175		-0.4	-0.3	DUF1611 domain-containing protein
MMP_RS06920		-0.4	-2.6	AAA family ATPase
MMP_RS06525		-0.4	-0.6	YciI family protein
MMP_RS04615		-0.4	-1.0	PDGLE domain-containing protein
MMP_RS07445		-0.4	-1.8	helix-turn-helix domain-containing protein
MMP_RS05560		-0.4	-1.6	deoxyuridine 5'-triphosphate nucleotidohydrolase
MMP_RS07695		-0.4	-2.1	DUF3236 domain-containing protein
MMP_RS03540		-0.4	-1.5	DUF2178 domain-containing protein
MMP_RS02195		-0.4	-1.0	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS08855		-0.4	-2.5	hypothetical protein
MMP_RS08645		-0.4	-1.6	UPF0179 family protein
MMP_RS01315		-0.4	-3.4	DUF2341 domain-containing protein
MMP_RS00090		-0.4	-1.4	CoA-binding protein
MMP_RS04255		-0.4	-1.9	coenzyme F420 hydrogenase subunit beta
MMP_RS09010		-0.4	-2.0	hypothetical protein
MMP_RS04620		-0.4	-2.3	cobalt transporter CbiM
MMP_RS00115		-0.4	-2.3	radical SAM protein
MMP_RS08165		-0.4	-0.7	phosphoglycerate dehydrogenase
MMP_RS01085		-0.4	-0.8	hypothetical protein
MMP_RS06530		-0.4	-1.5	bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
MMP_RS00245		-0.4	-3.2	type II secretion system F family protein
MMP_RS01430		-0.4	-2.2	mechanosensitive ion channel family protein
MMP_RS04585		-0.4	-2.1	AIR synthase related protein
MMP_RS08245		-0.4	-1.7	DUF4013 domain-containing protein
MMP_RS05850		-0.4	-0.7	Ldh family oxidoreductase
MMP_RS04990		-0.4	-2.2	aquaporin family protein
MMP_RS01280		-0.4	-2.5	DUF515 domain-containing protein
MMP_RS06400		-0.4	-0.4	4Fe-4S binding protein
MMP_RS06110		-0.4	-1.0	ATP-dependent protease LonB
MMP_RS04850		-0.4	-2.6	UPF0254 family protein
MMP_RS04780		-0.4	-0.7	ribonuclease P
MMP_RS04290		-0.4	-1.4	4Fe-4S binding protein
MMP_RS07540		-0.4	-1.0	CBS domain-containing protein
MMP_RS08635		-0.4	-0.7	UbiA family prenyltransferase
MMP_RS04410		-0.3	-1.1	hypothetical protein
MMP_RS06675		-0.3	-1.5	ADP-specific phosphofructokinase
MMP_RS07525		-0.3	-1.5	4Fe-4S binding protein
MMP_RS03495		-0.3	-1.8	Na/Pi cotransporter family protein
MMP_RS01270		-0.3	-2.9	prepilin peptidase
MMP_RS01620		-0.3	-0.8	hypothetical protein
MMP_RS01295		-0.3	-2.0	hypothetical protein
MMP_RS05245		-0.3	-1.1	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS04090		-0.3	-0.9	hypothetical protein
MMP_RS01880		-0.3	-1.5	DegT/DnrJ/EryC1/StrS family aminotransferase
MMP_RS06435		-0.3	-1.9	CBS domain-containing protein
MMP_RS06610		-0.3	-1.0	DUF2334 domain-containing protein
MMP_RS06020		-0.3	-1.3	archaeoflavoprotein AfpA
MMP_RS02290		-0.3	-2.0	MBL fold metallo-hydrolase
MMP_RS03245		-0.3	-1.4	DNA repair and recombination protein RadB
MMP_RS08940		-0.3	-0.5	MetS family NSS transporter small subunit
MMP_RS01790		-0.3	-1.8	restriction endonuclease
MMP_RS01725		-0.3	-1.2	class I SAM-dependent methyltransferase family protein
MMP_RS07710		-0.3	-1.1	cell division protein FtsZ
MMP_RS04815		-0.3	-1.9	chemotaxis protein CheD
MMP_RS09045		-0.3	-2.5	class III signal peptide-containing protein
MMP_RS05325		-0.3	-1.8	hypothetical protein
MMP_RS00520		-0.3	-0.4	RNA polymerase Rpb4 family protein
MMP_RS04125		-0.3	-1.4	TetR/AcrR family transcriptional regulator
MMP_RS05800		-0.3	-1.5	B12-binding domain-containing radical SAM protein
MMP_RS00735		-0.3	-1.4	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS02930		-0.3	-0.8	class I SAM-dependent methyltransferase
MMP_RS00140		-0.3	-1.5	DUF192 domain-containing protein
MMP_RS01895		-0.3	-2.2	flippase
MMP_RS08230		-0.3	-1.9	50S ribosomal protein L11 methyltransferase
MMP_RS04730		-0.3	-2.2	flavodoxin family protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium Chloride across organisms