Experiment set12S369 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS06840		-4.8	-1.1	DNA-directed RNA polymerase subunit N
MMP_RS03445		-4.1	-0.9	methanogenesis marker 17 protein
MMP_RS05355		-3.9	-0.9	hypothetical protein
MMP_RS00750		-3.8	-1.9	fumarate hydratase
MMP_RS05835		-3.8	-0.9	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS07555		-3.4	-0.8	monovalent cation/H+ antiporter subunit E
MMP_RS03300		-3.4	-0.8	TOBE domain-containing protein
MMP_RS03475		-3.0	-0.7	hypothetical protein
MMP_RS05920		-2.8	-0.6	50S ribosomal protein L37e
MMP_RS01180		-2.8	-1.9	XTP/dITP diphosphatase
MMP_RS07545		-2.8	-0.9	HTH domain-containing protein
MMP_RS02900		-2.6	-0.6	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS01265		-2.3	-2.3	hypothetical protein
MMP_RS02175		-2.1	-0.7	DUF1611 domain-containing protein
MMP_RS07735		-1.8	-0.6	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS08720		-1.8	-1.1	4Fe-4S binding protein
MMP_RS07860		-1.8	-0.6	hypothetical protein
MMP_RS01085		-1.8	-1.7	hypothetical protein
MMP_RS03640		-1.7	-1.9	archaeal proteasome endopeptidase complex subunit beta
MMP_RS08300		-1.7	-0.8	metal-sulfur cluster assembly factor
MMP_RS08595		-1.7	-0.9	flagellar protein C
MMP_RS06285		-1.6	-1.4	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS01500		-1.6	-1.4	CBS domain-containing protein
MMP_RS06895		-1.6	-1.0	selenocysteine-specific translation elongation factor
MMP_RS05450		-1.5	-1.6	CoB--CoM heterodisulfide reductase subunit C
MMP_RS01830		-1.5	-1.3	tRNA-Val
MMP_RS03385		-1.4	-0.8	cation diffusion facilitator family transporter
MMP_RS00730		-1.3	-3.2	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS00535		-1.3	-1.9	TIGR00375 family protein
MMP_RS00895		-1.3	-1.8	hypothetical protein
MMP_RS06355		-1.3	-1.3	molybdenum cofactor biosynthesis protein MoaE
MMP_RS05865		-1.2	-1.2	hypothetical protein
MMP_RS08370		-1.2	-0.5	cation:proton antiporter subunit C
MMP_RS07635		-1.2	-3.7	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS07730		-1.1	-1.3	pyruvate synthase subunit beta
MMP_RS03550		-1.1	-1.3	DUF2124 domain-containing protein
MMP_RS02045		-1.1	-1.0	tRNA-Met
MMP_RS05845		-1.1	-1.0	tRNA-intron lyase
MMP_RS08365		-1.0	-2.4	energy conserving hydrogenase EhbF
MMP_RS08435		-1.0	-0.8	Era-like GTP-binding protein
MMP_RS03450		-1.0	-1.4	glycine synthesis protein GlyXS (from data)
MMP_RS01745		-1.0	-2.0	AMP phosphorylase
MMP_RS07845		-1.0	-0.7	LL-diaminopimelate aminotransferase
MMP_RS07700		-0.9	-3.5	DUF1188 domain-containing protein
MMP_RS01110		-0.9	-2.0	FmdE family protein
MMP_RS00305		-0.9	-0.8	phosphoribosyl-ATP diphosphatase
MMP_RS04900		-0.9	-6.3	hypothetical protein
MMP_RS01925		-0.9	-3.7	DUF1616 domain-containing protein
MMP_RS02800		-0.9	-3.0	nucleotidyltransferase domain-containing protein
MMP_RS05815		-0.9	-0.7	NOL1/NOP2/sun family putative RNA methylase
MMP_RS06915		-0.9	-3.0	metallophosphoesterase
MMP_RS09035		-0.9	-1.8	hypothetical protein
MMP_RS00300		-0.9	-0.4	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS08860		-0.9	-1.8	MinD/ParA family protein
MMP_RS00965		-0.8	-1.1	hypothetical protein
MMP_RS07075		-0.8	-1.7	phosphomannomutase/phosphoglucomutase
MMP_RS02235		-0.8	-2.9	CBS domain-containing protein
MMP_RS05515		-0.8	-3.0	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS05990		-0.8	-1.4	DsrE family protein
MMP_RS04410		-0.8	-2.1	hypothetical protein
MMP_RS02605		-0.8	-0.4	MotA/TolQ/ExbB proton channel family protein
MMP_RS07815		-0.8	-0.6	DUF2120 domain-containing protein
MMP_RS01665		-0.8	-1.7	DUF2111 domain-containing protein
MMP_RS09020		-0.8	-0.6	hypothetical protein
MMP_RS02675		-0.8	-1.6	hypothetical protein
MMP_RS02195		-0.8	-0.9	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS05425		-0.8	-1.8	monovalent cation/H+ antiporter complex subunit F
MMP_RS06900		-0.8	-1.0	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS06860		-0.8	-0.8	4Fe-4S binding protein
MMP_RS03125		-0.7	-1.6	cell division ATPase MinD
MMP_RS08350		-0.7	-0.5	hypothetical protein
MMP_RS08725		-0.7	-0.8	Ni/Fe hydrogenase subunit alpha
MMP_RS07195		-0.7	-2.2	M20 family metallo-hydrolase
MMP_RS01150		-0.7	-1.5	aldo/keto reductase
MMP_RS06140		-0.7	-2.3	radical SAM protein
MMP_RS02910		-0.7	-1.3	ABC transporter substrate-binding protein
MMP_RS00655		-0.7	-0.9	hypothetical protein
MMP_RS05555		-0.7	-0.6	DUF4040 domain-containing protein
MMP_RS00850		-0.7	-1.5	TIGR01177 family methyltransferase
MMP_RS01020		-0.7	-0.5	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS02940		-0.7	-1.4	TatD family hydrolase
MMP_RS02765		-0.6	-1.6	ABC transporter ATP-binding protein
MMP_RS06600		-0.6	-0.6	class III signal peptide-containing protein
MMP_RS05825		-0.6	-1.3	peptidyl-prolyl cis-trans isomerase
MMP_RS06905		-0.6	-0.8	hypothetical protein
MMP_RS05560		-0.6	-2.3	deoxyuridine 5'-triphosphate nucleotidohydrolase
MMP_RS04955		-0.6	-1.8	DNA topoisomerase I
MMP_RS06445		-0.6	-1.2	DUF89 domain-containing protein
MMP_RS01030		-0.6	-1.6	MTAP family purine nucleoside phosphorylase
MMP_RS04720		-0.6	-1.1	DedA family protein
MMP_RS01575		-0.6	-1.8	aldolase
MMP_RS04475		-0.6	-2.1	nitrogen fixation
MMP_RS01310		-0.6	-3.3	hypothetical protein
MMP_RS04280		-0.6	-1.9	coenzyme F420-non-reducing hydrogenase subunit gamma
MMP_RS01295		-0.6	-2.8	hypothetical protein
MMP_RS03015		-0.6	-1.9	GTP 3' 8-cyclase MoaA
MMP_RS00240		-0.6	-3.2	type II secretion system F family protein
MMP_RS00250		-0.6	-4.0	Flp pilus assembly complex ATPase component TadA
MMP_RS04775		-0.6	-0.7	adenosylhomocysteinase
MMP_RS04615		-0.6	-1.1	PDGLE domain-containing protein
MMP_RS03465		-0.6	-0.4	adenine phosphoribosyltransferase
MMP_RS00735		-0.6	-1.2	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS00880		-0.5	-1.2	ribosome assembly RNA-binding protein YhbY
MMP_RS01385		-0.5	-0.2	imidazole glycerol phosphate synthase subunit HisH
MMP_RS00635		-0.5	-1.0	energy-coupling factor transporter transmembrane protein EcfT
MMP_RS07350		-0.5	-0.6	preprotein translocase subunit Sec61beta
MMP_RS00295		-0.5	-1.0	gamma carbonic anhydrase family protein
MMP_RS06760		-0.5	-1.3	hypothetical protein
MMP_RS03395		-0.5	-0.6	hypothetical protein
MMP_RS08095		-0.5	-1.8	dethiobiotin synthase
MMP_RS00915		-0.5	-1.3	DUF116 domain-containing protein
MMP_RS08645		-0.5	-1.8	UPF0179 family protein
MMP_RS06675		-0.5	-2.2	ADP-specific phosphofructokinase
MMP_RS02475		-0.5	-1.4	hypothetical protein
MMP_RS01495		-0.5	-1.6	TraB/GumN family protein
MMP_RS01790		-0.5	-2.6	restriction endonuclease
MMP_RS07390		-0.5	-0.8	cell division protein FtsZ
MMP_RS07575		-0.5	-1.1	RNA ligase partner protein
MMP_RS03965		-0.5	-0.8	hypothetical protein
MMP_RS08840		-0.5	-2.2	class I SAM-dependent methyltransferase
MMP_RS00245		-0.5	-3.6	type II secretion system F family protein
MMP_RS06395		-0.5	-0.7	ThiF family adenylyltransferase
MMP_RS02490		-0.5	-1.1	hypothetical protein
MMP_RS06920		-0.5	-1.7	AAA family ATPase
MMP_RS01305		-0.5	-3.3	hypothetical protein
MMP_RS00825		-0.5	-1.2	fumarylacetoacetate hydrolase family protein
MMP_RS08395		-0.5	-0.9	DsrE family protein
MMP_RS02405		-0.5	-1.2	hypothetical protein
MMP_RS08105		-0.5	-1.3	6-carboxyhexanoate--CoA ligase
MMP_RS04020		-0.5	-1.3	hypothetical protein
MMP_RS04945		-0.5	-1.1	hypothetical protein
MMP_RS04250		-0.5	-1.2	PC4/YdbC family ssDNA-binding protein
MMP_RS04125		-0.5	-1.4	TetR/AcrR family transcriptional regulator
MMP_RS03485		-0.5	-0.7	TIGR00267 family protein
MMP_RS00040		-0.5	-1.1	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS01315		-0.5	-3.6	DUF2341 domain-containing protein
MMP_RS05295		-0.5	-2.1	minichromosome maintenance protein MCM
MMP_RS07525		-0.5	-1.4	4Fe-4S binding protein
MMP_RS00570		-0.5	-1.0	protein-L-isoaspartate O-methyltransferase
MMP_RS01600		-0.5	-0.9	50S ribosomal protein L15e
MMP_RS06295		-0.5	-1.5	methanogenesis marker 14 protein
MMP_RS08230		-0.5	-1.4	50S ribosomal protein L11 methyltransferase
MMP_RS03535		-0.5	-0.5	helix-turn-helix transcriptional regulator
MMP_RS02015		-0.4	-1.1	amidohydrolase
MMP_RS07190		-0.4	-1.6	chromosome segregation protein SMC
MMP_RS06350		-0.4	-1.1	HesA/MoeB/ThiF family protein
MMP_RS06940		-0.4	-0.8	polyprenyl diphosphate synthase
MMP_RS00125		-0.4	-0.5	DUF2798 domain-containing protein
MMP_RS00090		-0.4	-1.1	CoA-binding protein
MMP_RS05905		-0.4	-1.6	undecaprenyl-diphosphate phosphatase
MMP_RS03225		-0.4	-1.5	acetolactate decarboxylase
MMP_RS00315		-0.4	-1.6	Nif3-like dinuclear metal center hexameric protein
MMP_RS05635		-0.4	-1.7	NAD-dependent epimerase/dehydratase family protein
MMP_RS01605		-0.4	-1.3	hypothetical protein
MMP_RS02745		-0.4	-0.8	hypothetical protein
MMP_RS07960		-0.4	-2.1	sugar phosphate isomerase/epimerase
MMP_RS00725		-0.4	-1.2	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS00150		-0.4	-1.3	AAA family ATPase
MMP_RS01290		-0.4	-2.1	class III signal peptide-containing protein
MMP_RS04390		-0.4	-1.9	hypothetical protein
MMP_RS01275		-0.4	-1.4	class III signal peptide-containing protein
MMP_RS03625		-0.4	-1.5	cell wall-binding protein
MMP_RS01225		-0.4	-0.9	DUF5379 domain-containing protein
MMP_RS06610		-0.4	-0.9	DUF2334 domain-containing protein
MMP_RS08330		-0.4	-0.8	NADH-quinone oxidoreductase subunit H
MMP_RS06525		-0.4	-0.4	YciI family protein
MMP_RS01120		-0.4	-1.4	permease
MMP_RS06055		-0.4	-1.3	peroxiredoxin
MMP_RS02955		-0.4	-1.1	DJ-1/PfpI family protein
MMP_RS02190		-0.4	-0.4	sulfopyruvate decarboxylase subunit alpha
MMP_RS08700		-0.4	-1.4	hypothetical protein
MMP_RS04690		-0.4	-0.8	class III signal peptide-containing protein
MMP_RS08100		-0.4	-0.9	8-amino-7-oxononanoate synthase
MMP_RS06970		-0.4	-1.3	ribosomal protein S18-alanine N-acetyltransferase
MMP_RS08745		-0.4	-1.1	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS04495		-0.4	-1.4	cation:proton antiporter
MMP_RS07775		-0.4	-0.9	alanine dehydrogenase
MMP_RS07645		-0.4	-1.5	aldehyde dehydrogenase family protein
MMP_RS08240		-0.4	-1.1	methanogenesis marker 16 metalloprotein
MMP_RS02390		-0.4	-1.5	NifB/NifX family molybdenum-iron cluster-binding protein
MMP_RS01280		-0.4	-2.2	DUF515 domain-containing protein
MMP_RS07695		-0.4	-1.2	DUF3236 domain-containing protein
MMP_RS03090		-0.4	-1.7	cation:proton antiporter
MMP_RS05875		-0.4	-1.2	hydroxyethylthiazole kinase
MMP_RS01200		-0.4	-1.4	hypothetical protein
MMP_RS04305		-0.4	-0.5	hypothetical protein
MMP_RS04845		-0.4	-1.1	CheF family chemotaxis protein
MMP_RS00120		-0.4	-1.0	LysR family transcriptional regulator
MMP_RS03275		-0.4	-1.2	TIGR00266 family protein
MMP_RS08855		-0.4	-1.7	hypothetical protein
MMP_RS02785		-0.4	-1.1	MarR family transcriptional regulator
MMP_RS03080		-0.4	-0.6	universal stress protein
MMP_RS01545		-0.4	-0.3	CBS domain-containing protein
MMP_RS07750		-0.4	-0.8	DUF357 domain-containing protein
MMP_RS04445		-0.4	-1.2	P-II family nitrogen regulator
MMP_RS06115		-0.4	-1.6	class II aldolase/adducin family protein
MMP_RS04850		-0.4	-2.2	UPF0254 family protein
MMP_RS07335		-0.4	-0.7	tRNA (cytidine(56)-2'-O)-methyltransferase
MMP_RS01685		-0.3	-0.8	indolepyruvate oxidoreductase subunit beta
MMP_RS02915		-0.3	-0.9	amino acid ABC transporter permease

Specific Phenotypes

For 2 genes in this experiment

For stress 5-fluorouracil in Methanococcus maripaludis S2

For stress 5-fluorouracil across organisms