Experiment set12S354 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete rubidium chloride 125 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS07605 +6.9 17.4 diadenylate cyclase compare
MMP_RS00185 +6.0 26.8 potassium channel protein compare
MMP_RS03700 +3.9 8.4 sodium:proton antiporter compare
MMP_RS06715 +2.2 8.2 cache domain-containing protein compare
MMP_RS06570 +2.0 5.1 DUF190 domain-containing protein compare
MMP_RS06720 +1.8 4.0 response regulator transcription factor compare
MMP_RS02605 +1.8 2.0 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS01775 +1.8 4.5 TIGR00297 family protein compare
MMP_RS03305 +1.8 3.4 winged helix-turn-helix domain-containing protein compare
MMP_RS02165 +1.7 4.2 tRNA-dihydrouridine synthase compare
MMP_RS06575 +1.6 3.9 fluoride efflux transporter CrcB compare
MMP_RS01055 +1.6 3.1 hypothetical protein compare
MMP_RS05545 +1.5 3.0 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS02110 +1.4 3.6 hypothetical protein compare
MMP_RS06860 +1.3 2.5 4Fe-4S binding protein compare
MMP_RS06130 +1.3 4.1 peptidylprolyl isomerase compare
MMP_RS03065 +1.2 4.4 AzlC family ABC transporter permease compare
MMP_RS02790 +1.2 1.6 class III signal peptide-containing protein compare
MMP_RS07765 +1.2 2.7 sodium:alanine symporter family protein compare
MMP_RS00990 +1.1 2.1 hypothetical protein compare
MMP_RS01980 +1.1 4.7 trimeric intracellular cation channel family protein compare
MMP_RS00705 +1.1 1.5 hypothetical protein compare
MMP_RS06200 +1.0 4.0 M24 family metallopeptidase compare
MMP_RS04875 +1.0 2.1 energy-converting hydrogenase B subunit P compare
MMP_RS08265 +1.0 1.9 rubrerythrin compare
MMP_RS08070 +1.0 4.8 DUF2096 domain-containing protein compare
MMP_RS08350 +1.0 1.2 hypothetical protein compare
MMP_RS02355 +1.0 1.9 30S ribosomal protein S27ae compare
MMP_RS01650 +1.0 0.9 sulfurtransferase TusA family protein compare
MMP_RS08315 +1.0 2.4 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS03220 +0.9 2.4 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS07860 +0.9 0.6 hypothetical protein compare
MMP_RS01640 +0.9 2.8 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMP_RS00375 +0.9 2.9 ammonium transporter compare
MMP_RS04145 +0.8 1.5 hypothetical protein compare
MMP_RS02340 +0.8 0.8 DNA-directed RNA polymerase subunit E'' compare
MMP_RS02595 +0.8 1.1 putative zinc-binding protein compare
MMP_RS08445 +0.8 1.8 DUF2099 family protein compare
MMP_RS03465 +0.8 1.0 adenine phosphoribosyltransferase compare
MMP_RS00655 +0.8 2.2 hypothetical protein compare
MMP_RS00795 +0.8 2.8 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS02370 +0.8 1.7 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS00855 +0.7 2.8 DUF367 family protein compare
MMP_RS03840 +0.7 2.6 hypothetical protein compare
MMP_RS04040 +0.7 1.3 hypothetical protein compare
MMP_RS02965 +0.7 1.8 carboxymuconolactone decarboxylase family protein compare
MMP_RS05250 +0.7 2.0 NFYB/HAP3 family transcription factor subunit compare
MMP_RS00770 +0.7 2.9 hypothetical protein compare
MMP_RS00400 +0.7 2.4 tributyrin esterase compare
MMP_RS06905 +0.7 1.1 hypothetical protein compare
MMP_RS08670 +0.7 1.8 metallophosphoesterase compare
MMP_RS01855 +0.7 2.5 2-hydroxyacyl-CoA dehydratase family protein compare
MMP_RS03845 +0.7 2.7 DNA adenine methylase compare
MMP_RS07125 +0.7 1.4 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS06685 +0.6 2.8 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS03440 +0.6 0.7 MoaD/ThiS family protein compare
MMP_RS07925 +0.6 1.5 haloacid dehalogenase compare
MMP_RS03775 +0.6 1.7 4Fe-4S dicluster domain-containing protein compare
MMP_RS08410 +0.6 2.8 DUF169 domain-containing protein compare
MMP_RS07680 +0.6 1.4 DUF366 family protein compare
MMP_RS06440 +0.6 1.4 CBS domain-containing protein compare
MMP_RS06865 +0.6 1.8 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS08085 +0.6 2.9 hypothetical protein compare
MMP_RS02740 +0.6 1.3 hypothetical protein compare
MMP_RS07150 +0.6 1.4 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS03800 +0.6 1.5 hypothetical protein compare
MMP_RS07195 +0.6 2.2 M20 family metallo-hydrolase compare
MMP_RS07885 +0.6 1.8 tripartite tricarboxylate transporter permease compare
MMP_RS08390 +0.6 1.9 DUF5400 domain-containing protein compare
MMP_RS08215 +0.6 0.8 DUF483 domain-containing protein compare
MMP_RS01675 +0.6 1.0 hypothetical protein compare
MMP_RS03115 +0.6 3.2 hypothetical protein compare
MMP_RS07435 +0.6 0.9 GMP synthase subunit A compare
MMP_RS03740 +0.6 2.4 indolepyruvate oxidoreductase subunit beta compare
MMP_RS05085 +0.6 2.0 AAA family ATPase compare
MMP_RS05780 +0.6 3.5 multidrug resistance efflux transporter family protein compare
MMP_RS05265 +0.6 1.0 2-isopropylmalate synthase compare
MMP_RS08725 +0.6 1.0 Ni/Fe hydrogenase subunit alpha compare
MMP_RS02410 +0.6 1.4 ABC transporter substrate-binding protein compare
MMP_RS01575 +0.6 2.0 aldolase compare
MMP_RS01525 +0.6 1.0 nucleoside-diphosphate kinase compare
MMP_RS02300 +0.5 2.1 NAD(P)H-dependent oxidoreductase compare
MMP_RS08325 +0.5 2.1 hypothetical protein compare
MMP_RS07130 +0.5 1.8 coenzyme F420 hydrogenase subunit gamma compare
MMP_RS01005 +0.5 0.6 riboflavin synthase compare
MMP_RS01750 +0.5 2.3 DUF63 family protein compare
MMP_RS04105 +0.5 2.4 MarR family transcriptional regulator compare
MMP_RS09025 +0.5 0.6 hypothetical protein compare
MMP_RS05140 +0.5 1.8 helix-turn-helix transcriptional regulator compare
MMP_RS02405 +0.5 2.2 hypothetical protein compare
MMP_RS06430 +0.5 1.5 6-carboxytetrahydropterin synthase QueD compare
MMP_RS03755 +0.5 2.3 MarR family transcriptional regulator compare
MMP_RS02085 +0.5 1.6 inosine/xanthosine triphosphatase compare
MMP_RS06545 +0.5 1.9 ferredoxin family protein compare
MMP_RS08260 +0.5 2.2 DUF99 family protein compare
MMP_RS07855 +0.5 2.4 class I SAM-dependent methyltransferase compare
MMP_RS02215 +0.5 2.0 ECF transporter S component compare
MMP_RS02455 +0.5 2.1 hypothetical protein compare
MMP_RS05155 +0.5 1.7 hypothetical protein compare
MMP_RS06910 +0.5 2.1 RlmF-related methyltransferase compare
MMP_RS05875 +0.5 1.6 hydroxyethylthiazole kinase compare
MMP_RS06190 +0.5 1.5 tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO compare
MMP_RS05275 +0.5 1.5 AI-2E family transporter compare
MMP_RS03765 +0.5 1.6 CopG family ribbon-helix-helix protein compare
MMP_RS05825 +0.5 1.7 peptidyl-prolyl cis-trans isomerase compare
MMP_RS04690 +0.5 0.9 class III signal peptide-containing protein compare
MMP_RS00565 +0.5 0.9 CBS domain-containing protein compare
MMP_RS08705 +0.5 1.5 sulfopyruvate decarboxylase subunit beta compare
MMP_RS05510 +0.5 1.4 Rrf2 family transcriptional regulator compare
MMP_RS01250 +0.4 1.5 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS00845 +0.4 2.4 acetate--CoA ligase compare
MMP_RS07120 +0.4 1.6 coenzyme F420 hydrogenase subunit alpha compare
MMP_RS06305 +0.4 2.3 transporter substrate-binding domain-containing protein compare
MMP_RS05955 +0.4 1.0 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS07095 +0.4 1.3 PspC domain-containing protein compare
MMP_RS00135 +0.4 1.7 DUF2121 domain-containing protein compare
MMP_RS00060 +0.4 0.8 3-dehydroquinate synthase II compare
MMP_RS01680 +0.4 1.7 phenylacetate--CoA ligase compare
MMP_RS07385 +0.4 0.8 protein translocase SEC61 complex subunit gamma compare
MMP_RS01110 +0.4 0.7 FmdE family protein compare
MMP_RS02870 +0.4 2.3 hypothetical protein compare
MMP_RS01320 +0.4 1.2 hypothetical protein compare
MMP_RS08630 +0.4 1.8 archaellar assembly protein FlaJ compare
MMP_RS08775 +0.4 1.2 methanogenesis marker 9 domain-containing protein compare
MMP_RS01895 +0.4 2.1 flippase compare
MMP_RS01645 +0.4 1.2 SWIM zinc finger family protein compare
MMP_RS07345 +0.4 1.4 glycine synthesis protein GlyXL (from data) compare
MMP_RS06155 +0.4 1.0 DUF4186 domain-containing protein compare
MMP_RS06520 +0.4 1.3 DUF1786 domain-containing protein compare
MMP_RS01570 +0.4 0.6 hypothetical protein compare
MMP_RS07645 +0.4 1.3 aldehyde dehydrogenase family protein compare
MMP_RS00830 +0.4 0.7 purine phosphoribosyltransferase family protein compare
MMP_RS02315 +0.4 1.5 RimK family alpha-L-glutamate ligase compare
MMP_RS06680 +0.4 1.9 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS01780 +0.4 1.7 TrmJ/YjtD family RNA methyltransferase compare
MMP_RS02295 +0.4 1.9 TatD family hydrolase compare
MMP_RS01090 +0.4 1.8 ABC transporter substrate-binding protein compare
MMP_RS05895 +0.4 1.6 metallophosphoesterase compare
MMP_RS03405 +0.4 1.0 RNA 3'-terminal phosphate cyclase compare
MMP_RS01630 +0.4 1.6 N-glycosylase/DNA lyase compare
MMP_RS08100 +0.4 1.4 8-amino-7-oxononanoate synthase compare
MMP_RS02720 +0.4 0.7 molybdate ABC transporter substrate-binding protein compare
MMP_RS02440 +0.4 1.7 hypothetical protein compare
MMP_RS04880 +0.4 2.2 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS02810 +0.4 1.7 hypothetical protein compare
MMP_RS07815 +0.4 0.5 DUF2120 domain-containing protein compare
MMP_RS08285 +0.4 1.9 serine/threonine protein kinase compare
MMP_RS04900 +0.4 2.5 hypothetical protein compare
MMP_RS00980 +0.4 2.0 hypothetical protein compare
MMP_RS00395 +0.4 0.6 MGMT family protein compare
MMP_RS04735 +0.4 1.6 tautomerase family protein compare
MMP_RS04060 +0.4 1.8 hypothetical protein compare
MMP_RS06915 +0.4 0.8 metallophosphoesterase compare
MMP_RS03585 +0.4 0.5 Hsp20/alpha crystallin family protein compare
MMP_RS03875 +0.4 1.0 hypothetical protein compare
MMP_RS06290 +0.4 1.4 DNA repair and recombination protein RadA compare
MMP_RS00305 +0.4 0.5 phosphoribosyl-ATP diphosphatase compare
MMP_RS08915 +0.4 1.2 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS06165 +0.4 1.1 ABC transporter permease compare
MMP_RS04165 +0.4 1.2 TetR/AcrR family transcriptional regulator compare
MMP_RS02680 +0.4 1.3 ABC transporter permease compare
MMP_RS07890 +0.4 0.7 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS07915 +0.4 1.2 DUF4870 domain-containing protein compare
MMP_RS00950 +0.4 1.8 site-2 protease family protein compare
MMP_RS05820 +0.4 1.4 RNA-binding transcriptional accessory protein compare
MMP_RS06965 +0.4 0.8 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS01115 +0.3 1.6 molybdopterin molybdotransferase MoeA compare
MMP_RS03265 +0.3 1.8 sugar phosphate isomerase/epimerase compare
MMP_RS01150 +0.3 1.4 aldo/keto reductase compare
MMP_RS00435 +0.3 1.8 CPBP family intramembrane metalloprotease compare
MMP_RS07135 +0.3 1.6 coenzyme F420 hydrogenase subunit beta compare
MMP_RS08580 +0.3 0.5 flagellin compare
MMP_RS07715 +0.3 1.6 YfcE family phosphodiesterase compare
MMP_RS03895 +0.3 0.8 hypothetical protein compare
MMP_RS02380 +0.3 1.3 ATP-binding protein compare
MMP_RS08645 +0.3 0.9 UPF0179 family protein compare
MMP_RS06975 +0.3 0.6 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS06515 +0.3 0.7 UPF0489 family protein compare
MMP_RS08480 +0.3 2.0 molybdate ABC transporter substrate-binding protein compare
MMP_RS08850 +0.3 2.2 hypothetical protein compare
MMP_RS02840 +0.3 1.1 DUF123 domain-containing protein compare
MMP_RS06445 +0.3 1.0 DUF89 domain-containing protein compare
MMP_RS05975 +0.3 1.4 hypothetical protein compare
MMP_RS01985 +0.3 1.2 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS06175 +0.3 1.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS06325 +0.3 0.4 hypothetical protein compare
MMP_RS05080 +0.3 1.8 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS02975 +0.3 1.0 DUF2124 domain-containing protein compare
MMP_RS06300 +0.3 1.1 ABC transporter substrate-binding protein compare
MMP_RS05595 +0.3 1.5 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01010 +0.3 1.3 DUF4352 domain-containing protein compare
MMP_RS03340 +0.3 0.3 ABC transporter ATP-binding protein compare
MMP_RS02590 +0.3 1.3 low molecular weight phosphatase family protein compare
MMP_RS09050 +0.3 0.9 CAP domain-containing protein compare
MMP_RS07705 +0.3 1.1 transcriptional regulator compare
MMP_RS08080 +0.3 1.0 YchF/TatD family DNA exonuclease compare
MMP_RS07835 +0.3 0.8 TldD/PmbA family protein compare
MMP_RS00235 +0.3 1.4 HDIG domain-containing protein compare
MMP_RS04405 +0.3 1.3 hypothetical protein compare
MMP_RS07805 +0.3 1.0 ABC transporter permease compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress rubidium chloride across organisms