Experiment set12S351 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete Zinc Pyrithione 0.0142857142857143 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS01195 -5.4 -0.8 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS07005 -5.3 -0.5 4Fe-4S binding protein compare
MMP_RS01020 -5.0 -0.8 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS05550 -4.6 -0.6 cation:proton antiporter compare
MMP_RS08435 -4.4 -1.9 Era-like GTP-binding protein compare
MMP_RS01610 -4.2 -2.4 hypothetical protein compare
MMP_RS06730 -3.9 -1.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS03315 -3.8 -1.0 ferrous iron transport protein A compare
MMP_RS07845 -3.8 -2.5 LL-diaminopimelate aminotransferase compare
MMP_RS01265 -3.7 -2.3 hypothetical protein compare
MMP_RS00730 -3.6 -5.6 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS08675 -3.4 -2.1 class III signal peptide-containing protein compare
MMP_RS01755 -3.4 -1.1 DUF2097 domain-containing protein compare
MMP_RS08720 -3.3 -1.3 4Fe-4S binding protein compare
MMP_RS07635 -3.2 -7.8 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06350 -3.2 -6.2 HesA/MoeB/ThiF family protein compare
MMP_RS01385 -3.1 -0.5 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS08785 -3.0 -0.7 RNA-protein complex protein Nop10 compare
MMP_RS01085 -3.0 -1.5 hypothetical protein compare
MMP_RS03640 -3.0 -2.9 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06400 -3.0 -1.2 4Fe-4S binding protein compare
MMP_RS08300 -2.9 -1.0 metal-sulfur cluster assembly factor compare
MMP_RS01175 -2.9 -3.3 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS02800 -2.9 -7.1 nucleotidyltransferase domain-containing protein compare
MMP_RS03015 -2.9 -8.6 GTP 3' 8-cyclase MoaA compare
MMP_RS08745 -2.8 -6.2 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06355 -2.8 -2.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS05515 -2.8 -5.8 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS02900 -2.8 -0.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS01190 -2.7 -7.0 cadmium-translocating P-type ATPase conserved
MMP_RS01545 -2.7 -0.9 CBS domain-containing protein compare
MMP_RS03025 -2.7 -4.3 molybdenum cofactor guanylyltransferase compare
MMP_RS00040 -2.7 -5.2 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS02145 -2.7 -6.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS06625 -2.7 -1.5 DNA primase compare
MMP_RS04900 -2.7 -18.0 hypothetical protein compare
MMP_RS05635 -2.7 -8.9 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS01225 -2.6 -4.2 DUF5379 domain-containing protein compare
MMP_RS07755 -2.6 -1.0 DUF555 domain-containing protein compare
MMP_RS01270 -2.6 -14.8 prepilin peptidase compare
MMP_RS06035 -2.5 -9.8 glycosyltransferase family 2 protein compare
MMP_RS02195 -2.5 -3.0 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS09055 -2.5 -0.8 CAP domain-containing protein compare
MMP_RS08855 -2.5 -9.7 hypothetical protein compare
MMP_RS00725 -2.5 -7.0 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS06840 -2.5 -0.9 DNA-directed RNA polymerase subunit N compare
MMP_RS03580 -2.5 -2.8 signal recognition particle-docking protein FtsY compare
MMP_RS02230 -2.4 -10.2 sodium-dependent transporter compare
MMP_RS06725 -2.4 -7.9 hypothetical protein compare
MMP_RS07695 -2.4 -5.9 DUF3236 domain-containing protein compare
MMP_RS00245 -2.4 -16.1 type II secretion system F family protein compare
MMP_RS07700 -2.4 -9.7 DUF1188 domain-containing protein compare
MMP_RS07555 -2.4 -0.6 monovalent cation/H+ antiporter subunit E compare
MMP_RS01310 -2.4 -11.8 hypothetical protein compare
MMP_RS07540 -2.4 -2.7 CBS domain-containing protein compare
MMP_RS05425 -2.4 -4.1 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS05925 -2.4 -3.0 small nuclear ribonucleoprotein compare
MMP_RS02235 -2.3 -9.8 CBS domain-containing protein compare
MMP_RS01900 -2.3 -12.2 hypothetical protein compare
MMP_RS00250 -2.3 -15.2 Flp pilus assembly complex ATPase component TadA compare
MMP_RS04850 -2.3 -14.9 UPF0254 family protein compare
MMP_RS01305 -2.3 -14.9 hypothetical protein compare
MMP_RS07200 -2.3 -5.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS00985 -2.3 -4.9 CDC48 family AAA ATPase compare
MMP_RS01500 -2.3 -1.7 CBS domain-containing protein compare
MMP_RS03475 -2.3 -0.5 hypothetical protein compare
MMP_RS00695 -2.3 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS07355 -2.3 -0.7 transcription factor S compare
MMP_RS03700 -2.3 -6.4 sodium:proton antiporter compare
MMP_RS03095 -2.2 -5.3 diphthine synthase compare
MMP_RS06900 -2.2 -1.9 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS02355 -2.2 -2.1 30S ribosomal protein S27ae compare
MMP_RS01295 -2.2 -9.8 hypothetical protein compare
MMP_RS08940 -2.2 -1.0 MetS family NSS transporter small subunit compare
MMP_RS00240 -2.2 -12.5 type II secretion system F family protein compare
MMP_RS07600 -2.2 -1.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS08715 -2.2 -1.1 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07330 -2.2 -15.3 membrane protein compare
MMP_RS03080 -2.2 -3.1 universal stress protein compare
MMP_RS01285 -2.2 -8.9 hypothetical protein compare
MMP_RS01875 -2.2 -8.1 N-acetyltransferase compare
MMP_RS09020 -2.2 -1.3 hypothetical protein compare
MMP_RS01290 -2.1 -10.0 class III signal peptide-containing protein compare
MMP_RS05580 -2.1 -13.5 glycosyltransferase compare
MMP_RS06395 -2.1 -2.7 ThiF family adenylyltransferase compare
MMP_RS08820 -2.1 -3.8 hypothetical protein compare
MMP_RS03035 -2.1 -2.4 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS06895 -2.1 -1.2 selenocysteine-specific translation elongation factor compare
MMP_RS07750 -2.1 -5.1 DUF357 domain-containing protein compare
MMP_RS01925 -2.1 -7.8 DUF1616 domain-containing protein compare
MMP_RS01075 -2.1 -1.0 hypothetical protein compare
MMP_RS07710 -2.1 -5.3 cell division protein FtsZ compare
MMP_RS03250 -2.1 -3.3 MJ1244 family protein compare
MMP_RS02875 -2.1 -6.9 chorismate pyruvate-lyase family protein compare
MMP_RS06020 -2.1 -3.4 archaeoflavoprotein AfpA compare
MMP_RS01905 -2.1 -11.6 glycosyltransferase compare
MMP_RS05540 -2.1 -3.2 hypothetical protein compare
MMP_RS01880 -2.0 -5.0 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01955 -2.0 -2.2 hypothetical protein compare
MMP_RS01280 -2.0 -10.8 DUF515 domain-containing protein compare
MMP_RS08195 -2.0 -8.0 hypothetical protein compare
MMP_RS02240 -2.0 -1.9 methanogenesis marker 7 protein compare
MMP_RS07075 -2.0 -2.8 phosphomannomutase/phosphoglucomutase compare
MMP_RS00810 -2.0 -5.6 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS01890 -1.9 -2.1 nucleotide sugar dehydrogenase compare
MMP_RS05815 -1.9 -1.6 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08995 -1.9 -0.9 hypothetical protein compare
MMP_RS01315 -1.9 -13.9 DUF2341 domain-containing protein compare
MMP_RS06295 -1.9 -5.6 methanogenesis marker 14 protein compare
MMP_RS06885 -1.9 -1.9 50S ribosome-binding GTPase compare
MMP_RS03535 -1.9 -2.3 helix-turn-helix transcriptional regulator compare
MMP_RS02345 -1.9 -2.8 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS03125 -1.9 -4.8 cell division ATPase MinD compare
MMP_RS01885 -1.8 -4.4 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS06340 -1.8 -5.4 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS03110 -1.8 -4.0 glycosyltransferase family 2 protein compare
MMP_RS01220 -1.8 -4.8 hypothetical protein compare
MMP_RS06855 -1.8 -7.5 hypothetical protein compare
MMP_RS03445 -1.8 -0.7 methanogenesis marker 17 protein compare
MMP_RS05850 -1.8 -2.2 Ldh family oxidoreductase compare
MMP_RS02340 -1.8 -1.3 DNA-directed RNA polymerase subunit E'' compare
MMP_RS05430 -1.8 -3.5 TIGR00288 family NYN domain-containing protein compare
MMP_RS00895 -1.7 -2.5 hypothetical protein compare
MMP_RS00315 -1.7 -5.4 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS06105 -1.7 -5.4 hydrogenase maturation peptidase HycI compare
MMP_RS04585 -1.7 -6.0 AIR synthase related protein compare
MMP_RS03435 -1.7 -1.0 ketol-acid reductoisomerase compare
MMP_RS07390 -1.7 -1.9 cell division protein FtsZ compare
MMP_RS07820 -1.7 -2.5 UPF0104 family protein compare
MMP_RS01275 -1.7 -3.7 class III signal peptide-containing protein compare
MMP_RS02245 -1.6 -2.1 hypothetical protein compare
MMP_RS06015 -1.6 -3.5 flavodoxin family protein compare
MMP_RS04710 -1.6 -1.3 hypothetical protein compare
MMP_RS06980 -1.6 -4.6 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS00735 -1.6 -1.8 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS05920 -1.6 -0.4 50S ribosomal protein L37e compare
MMP_RS01005 -1.6 -0.8 riboflavin synthase compare
MMP_RS07425 -1.6 -3.4 GTP-binding protein compare
MMP_RS00750 -1.5 -1.3 fumarate hydratase compare
MMP_RS08645 -1.5 -3.9 UPF0179 family protein compare
MMP_RS08790 -1.5 -1.1 translation initiation factor IF-2 subunit alpha compare
MMP_RS02545 -1.5 -2.7 hypothetical protein compare
MMP_RS06865 -1.5 -1.6 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS07955 -1.5 -3.2 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS04685 -1.5 -1.8 DUF126 domain-containing protein compare
MMP_RS01380 -1.5 -1.9 PHP domain-containing protein compare
MMP_RS08860 -1.5 -4.3 MinD/ParA family protein compare
MMP_RS06670 -1.4 -3.0 glucose-6-phosphate isomerase compare
MMP_RS09045 -1.4 -8.6 class III signal peptide-containing protein compare
MMP_RS01365 -1.4 -1.8 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS02780 -1.4 -6.1 hypothetical protein compare
MMP_RS08595 -1.4 -0.6 flagellar protein C compare
MMP_RS01140 -1.4 -2.2 molybdate ABC transporter permease subunit compare
MMP_RS01045 -1.4 -3.4 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS03600 -1.4 -1.4 triose-phosphate isomerase compare
MMP_RS07420 -1.4 -3.0 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS04605 -1.4 -2.5 cobalt ECF transporter T component CbiQ compare
MMP_RS08975 -1.4 -2.7 hypothetical protein compare
MMP_RS06600 -1.4 -0.7 class III signal peptide-containing protein compare
MMP_RS03400 -1.4 -1.2 archease compare
MMP_RS00110 -1.4 -1.9 hypothetical protein compare
MMP_RS06925 -1.4 -1.5 ribonuclease VapC4 compare
MMP_RS01325 -1.3 -1.0 dihydroneopterin aldolase family protein compare
MMP_RS03205 -1.3 -0.9 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS00320 -1.3 -1.0 class I SAM-dependent methyltransferase compare
MMP_RS02010 -1.3 -4.4 PHP domain-containing protein compare
MMP_RS02190 -1.3 -1.6 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS01840 -1.3 -3.5 TIGR00289 family protein compare
MMP_RS00535 -1.3 -0.7 TIGR00375 family protein compare
MMP_RS03485 -1.3 -2.5 TIGR00267 family protein compare
MMP_RS00305 -1.3 -0.9 phosphoribosyl-ATP diphosphatase compare
MMP_RS05245 -1.3 -4.9 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS00115 -1.3 -5.9 radical SAM protein compare
MMP_RS00310 -1.3 -5.8 CBS domain-containing protein compare
MMP_RS03390 -1.3 -4.3 malate dehydrogenase compare
MMP_RS01975 -1.3 -8.1 hypothetical protein compare
MMP_RS07900 -1.3 -1.5 YeeE/YedE family protein compare
MMP_RS01910 -1.3 -5.5 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS05910 -1.3 -1.9 cell division ATPase MinD compare
MMP_RS04775 -1.2 -2.1 adenosylhomocysteinase compare
MMP_RS00720 -1.2 -4.1 metal-dependent hydrolase compare
MMP_RS07580 -1.2 -1.4 DUF356 domain-containing protein compare
MMP_RS03145 -1.2 -3.0 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS00120 -1.2 -2.7 LysR family transcriptional regulator compare
MMP_RS01725 -1.2 -1.6 class I SAM-dependent methyltransferase family protein compare
MMP_RS06230 -1.2 -1.5 helix-turn-helix domain-containing protein compare
MMP_RS01665 -1.2 -1.9 DUF2111 domain-containing protein compare
MMP_RS01800 -1.2 -1.9 TIGR00303 family protein compare
MMP_RS05345 -1.2 -3.9 hypothetical protein compare
MMP_RS03140 -1.2 -4.5 hypothetical protein compare
MMP_RS05955 -1.2 -1.1 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS05445 -1.2 -3.6 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS02135 -1.2 -2.6 DUF5612 domain-containing protein compare
MMP_RS05765 -1.2 -2.5 M42 family metallopeptidase compare
MMP_RS04695 -1.2 -4.4 selenide water dikinase SelD compare
MMP_RS05950 -1.1 -3.1 nickel-dependent hydrogenase large subunit compare
MMP_RS06315 -1.1 -0.5 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS00570 -1.1 -1.1 protein-L-isoaspartate O-methyltransferase compare
MMP_RS08830 -1.1 -3.3 GTP-binding protein compare
MMP_RS00880 -1.1 -1.6 ribosome assembly RNA-binding protein YhbY compare


Specific Phenotypes

For 1 genes in this experiment

For stress Zinc Pyrithione in Methanococcus maripaludis S2

For stress Zinc Pyrithione across organisms