Experiment set12S350 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete Nitrofurantoin 0.1 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS06625 -7.5 -1.4 DNA primase compare
MMP_RS01020 -7.1 -0.6 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07380 -6.9 -1.4 transcription elongation factor Spt5 compare
MMP_RS01755 -5.9 -0.8 DUF2097 domain-containing protein compare
MMP_RS05550 -5.9 -0.5 cation:proton antiporter compare
MMP_RS00300 -5.8 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS07555 -5.8 -0.5 monovalent cation/H+ antiporter subunit E compare
MMP_RS08635 -5.7 -1.3 UbiA family prenyltransferase compare
MMP_RS03475 -5.6 -0.5 hypothetical protein compare
MMP_RS04685 -5.4 -2.6 DUF126 domain-containing protein compare
MMP_RS07005 -5.3 -0.5 4Fe-4S binding protein compare
MMP_RS07545 -5.2 -0.7 HTH domain-containing protein compare
MMP_RS01265 -5.1 -2.3 hypothetical protein compare
MMP_RS00515 -4.9 -0.6 DUF655 domain-containing protein compare
MMP_RS06400 -4.8 -1.2 4Fe-4S binding protein compare
MMP_RS06315 -4.6 -0.6 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS04710 -4.4 -1.6 hypothetical protein compare
MMP_RS02240 -4.3 -2.6 methanogenesis marker 7 protein compare
MMP_RS06925 -4.0 -2.0 ribonuclease VapC4 compare
MMP_RS06350 -4.0 -6.1 HesA/MoeB/ThiF family protein compare
MMP_RS04900 -4.0 -15.9 hypothetical protein compare
MMP_RS05865 -3.8 -2.4 hypothetical protein compare
MMP_RS02875 -3.7 -5.7 chorismate pyruvate-lyase family protein compare
MMP_RS08165 -3.7 -2.3 phosphoglycerate dehydrogenase compare
MMP_RS01795 -3.6 -1.1 methanogenesis marker 6 protein compare
MMP_RS03640 -3.6 -2.5 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS08435 -3.6 -1.6 Era-like GTP-binding protein compare
MMP_RS01500 -3.6 -1.7 CBS domain-containing protein compare
MMP_RS01325 -3.5 -1.6 dihydroneopterin aldolase family protein compare
MMP_RS06355 -3.5 -2.1 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS03080 -3.4 -2.3 universal stress protein compare
MMP_RS07635 -3.4 -5.7 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS05425 -3.3 -3.2 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS03315 -3.3 -0.8 ferrous iron transport protein A compare
MMP_RS06840 -3.2 -0.9 DNA-directed RNA polymerase subunit N compare
MMP_RS02235 -3.2 -7.8 CBS domain-containing protein compare
MMP_RS08000 -3.1 -9.8 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS07075 -3.1 -3.0 phosphomannomutase/phosphoglucomutase compare
MMP_RS01665 -3.0 -3.0 DUF2111 domain-containing protein compare
MMP_RS05515 -3.0 -5.1 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS03435 -2.9 -1.4 ketol-acid reductoisomerase compare
MMP_RS01075 -2.9 -1.7 hypothetical protein compare
MMP_RS06675 -2.8 -7.9 ADP-specific phosphofructokinase compare
MMP_RS06725 -2.8 -6.2 hypothetical protein compare
MMP_RS05925 -2.8 -2.5 small nuclear ribonucleoprotein compare
MMP_RS00315 -2.7 -4.2 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS05635 -2.7 -5.6 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS03250 -2.7 -2.6 MJ1244 family protein compare
MMP_RS07330 -2.6 -12.8 membrane protein compare
MMP_RS08785 -2.6 -0.7 RNA-protein complex protein Nop10 compare
MMP_RS06120 -2.6 -1.7 UPF0147 family protein compare
MMP_RS06730 -2.6 -1.4 phosphopantothenate/pantothenate synthetase compare
MMP_RS08350 -2.5 -0.8 hypothetical protein compare
MMP_RS07700 -2.5 -7.6 DUF1188 domain-containing protein compare
MMP_RS06395 -2.5 -2.7 ThiF family adenylyltransferase compare
MMP_RS01900 -2.5 -8.8 hypothetical protein compare
MMP_RS02290 -2.5 -6.5 MBL fold metallo-hydrolase compare
MMP_RS05580 -2.5 -11.9 glycosyltransferase compare
MMP_RS07695 -2.4 -3.4 DUF3236 domain-containing protein compare
MMP_RS08675 -2.4 -1.9 class III signal peptide-containing protein compare
MMP_RS01270 -2.4 -9.0 prepilin peptidase compare
MMP_RS02800 -2.3 -4.7 nucleotidyltransferase domain-containing protein compare
MMP_RS03015 -2.3 -4.6 GTP 3' 8-cyclase MoaA compare
MMP_RS05345 -2.3 -3.9 hypothetical protein compare
MMP_RS06295 -2.3 -4.1 methanogenesis marker 14 protein compare
MMP_RS08790 -2.3 -1.4 translation initiation factor IF-2 subunit alpha compare
MMP_RS05695 -2.3 -4.8 phospholipase D-like domain-containing protein compare
MMP_RS01905 -2.3 -8.0 glycosyltransferase compare
MMP_RS01880 -2.3 -3.4 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS00685 -2.2 -2.2 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01545 -2.2 -0.9 CBS domain-containing protein compare
MMP_RS03960 -2.2 -1.0 hypothetical protein compare
MMP_RS08650 -2.2 -2.7 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS00735 -2.2 -3.0 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS01575 -2.2 -3.7 aldolase compare
MMP_RS06035 -2.2 -6.3 glycosyltransferase family 2 protein compare
MMP_RS07630 -2.2 -1.2 ATP-binding cassette domain-containing protein compare
MMP_RS01280 -2.2 -8.9 DUF515 domain-containing protein compare
MMP_RS00730 -2.2 -3.7 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS08745 -2.2 -3.2 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS05920 -2.2 -0.5 50S ribosomal protein L37e compare
MMP_RS01875 -2.2 -5.8 N-acetyltransferase compare
MMP_RS08300 -2.1 -0.9 metal-sulfur cluster assembly factor compare
MMP_RS07600 -2.1 -1.2 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS08715 -2.1 -0.9 formylmethanofuran dehydrogenase subunit B compare
MMP_RS01925 -2.1 -4.5 DUF1616 domain-containing protein compare
MMP_RS08195 -2.1 -6.0 hypothetical protein compare
MMP_RS01385 -2.1 -0.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS03580 -2.0 -2.4 signal recognition particle-docking protein FtsY compare
MMP_RS01275 -2.0 -3.8 class III signal peptide-containing protein compare
MMP_RS03120 -2.0 -2.6 hypothetical protein compare
MMP_RS07730 -2.0 -1.6 pyruvate synthase subunit beta compare
MMP_RS07090 -2.0 -5.9 tRNA (adenine-N1)-methyltransferase compare
MMP_RS06175 -2.0 -3.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS06885 -2.0 -1.9 50S ribosome-binding GTPase compare
MMP_RS04850 -2.0 -8.9 UPF0254 family protein compare
MMP_RS01195 -2.0 -1.0 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01885 -2.0 -3.8 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS02145 -2.0 -5.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS01800 -2.0 -2.3 TIGR00303 family protein compare
MMP_RS04605 -1.9 -2.9 cobalt ECF transporter T component CbiQ compare
MMP_RS00810 -1.9 -4.3 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS01310 -1.9 -7.9 hypothetical protein compare
MMP_RS00240 -1.9 -8.4 type II secretion system F family protein compare
MMP_RS00250 -1.9 -9.2 Flp pilus assembly complex ATPase component TadA compare
MMP_RS03110 -1.9 -3.9 glycosyltransferase family 2 protein compare
MMP_RS00985 -1.9 -3.3 CDC48 family AAA ATPase compare
MMP_RS05640 -1.8 -3.7 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS00040 -1.8 -4.3 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS00245 -1.8 -10.8 type II secretion system F family protein compare
MMP_RS01745 -1.8 -5.2 AMP phosphorylase compare
MMP_RS07420 -1.8 -3.1 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06340 -1.8 -3.2 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS01290 -1.8 -5.9 class III signal peptide-containing protein compare
MMP_RS07390 -1.8 -1.4 cell division protein FtsZ compare
MMP_RS01610 -1.8 -2.2 hypothetical protein compare
MMP_RS08330 -1.8 -3.5 NADH-quinone oxidoreductase subunit H compare
MMP_RS00725 -1.8 -4.7 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS03390 -1.8 -4.5 malate dehydrogenase compare
MMP_RS00060 -1.8 -1.4 3-dehydroquinate synthase II compare
MMP_RS07525 -1.7 -5.5 4Fe-4S binding protein compare
MMP_RS01225 -1.7 -2.5 DUF5379 domain-containing protein compare
MMP_RS01175 -1.7 -1.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03400 -1.7 -1.2 archease compare
MMP_RS04615 -1.7 -1.6 PDGLE domain-containing protein compare
MMP_RS01890 -1.7 -2.7 nucleotide sugar dehydrogenase compare
MMP_RS01285 -1.7 -7.0 hypothetical protein compare
MMP_RS08855 -1.7 -7.3 hypothetical protein compare
MMP_RS07605 -1.7 -2.6 diadenylate cyclase compare
MMP_RS07575 -1.7 -2.8 RNA ligase partner protein compare
MMP_RS01295 -1.6 -6.4 hypothetical protein compare
MMP_RS08860 -1.6 -3.1 MinD/ParA family protein compare
MMP_RS07845 -1.6 -1.7 LL-diaminopimelate aminotransferase compare
MMP_RS05415 -1.6 -3.2 DUF22 domain-containing protein compare
MMP_RS08645 -1.6 -3.5 UPF0179 family protein compare
MMP_RS04585 -1.6 -4.7 AIR synthase related protein compare
MMP_RS05430 -1.5 -3.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS05250 -1.5 -2.3 NFYB/HAP3 family transcription factor subunit compare
MMP_RS05845 -1.5 -0.8 tRNA-intron lyase compare
MMP_RS04620 -1.5 -4.1 cobalt transporter CbiM compare
MMP_RS02780 -1.5 -5.1 hypothetical protein compare
MMP_RS08940 -1.5 -0.9 MetS family NSS transporter small subunit compare
MMP_RS04485 -1.5 -5.5 putative beta-lysine N-acetyltransferase compare
MMP_RS07625 -1.5 -1.3 cobalt ECF transporter T component CbiQ compare
MMP_RS01305 -1.5 -8.4 hypothetical protein compare
MMP_RS01315 -1.5 -9.9 DUF2341 domain-containing protein compare
MMP_RS03445 -1.4 -0.6 methanogenesis marker 17 protein compare
MMP_RS00915 -1.4 -3.0 DUF116 domain-containing protein compare
MMP_RS04955 -1.4 -3.6 DNA topoisomerase I compare
MMP_RS01895 -1.4 -6.7 flippase compare
MMP_RS01380 -1.4 -2.0 PHP domain-containing protein compare
MMP_RS03125 -1.4 -4.2 cell division ATPase MinD compare
MMP_RS01085 -1.4 -1.2 hypothetical protein compare
MMP_RS07540 -1.4 -1.8 CBS domain-containing protein compare
MMP_RS01975 -1.4 -6.8 hypothetical protein compare
MMP_RS07200 -1.4 -3.2 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS08460 -1.4 -1.1 proteasome-activating nucleotidase compare
MMP_RS01910 -1.4 -4.8 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS03700 -1.4 -3.4 sodium:proton antiporter compare
MMP_RS02345 -1.3 -2.0 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS03095 -1.3 -3.0 diphthine synthase compare
MMP_RS05910 -1.3 -1.6 cell division ATPase MinD compare
MMP_RS08225 -1.3 -4.3 RimK family alpha-L-glutamate ligase compare
MMP_RS03440 -1.3 -0.6 MoaD/ThiS family protein compare
MMP_RS05555 -1.3 -0.7 DUF4040 domain-containing protein compare
MMP_RS05295 -1.3 -4.9 minichromosome maintenance protein MCM compare
MMP_RS00185 -1.3 -5.1 potassium channel protein compare
MMP_RS03535 -1.3 -1.4 helix-turn-helix transcriptional regulator compare
MMP_RS03025 -1.3 -2.3 molybdenum cofactor guanylyltransferase compare
MMP_RS02930 -1.3 -1.3 class I SAM-dependent methyltransferase compare
MMP_RS01370 -1.3 -4.9 acetate--CoA ligase family protein compare
MMP_RS05850 -1.3 -1.9 Ldh family oxidoreductase compare
MMP_RS04720 -1.3 -1.3 DedA family protein compare
MMP_RS03020 -1.3 -2.2 peptidylprolyl isomerase compare
MMP_RS00305 -1.3 -0.8 phosphoribosyl-ATP diphosphatase compare
MMP_RS00320 -1.2 -1.0 class I SAM-dependent methyltransferase compare
MMP_RS06310 -1.2 -2.4 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS07710 -1.2 -3.1 cell division protein FtsZ compare
MMP_RS00140 -1.2 -2.6 DUF192 domain-containing protein compare
MMP_RS06895 -1.2 -0.8 selenocysteine-specific translation elongation factor compare
MMP_RS06170 -1.2 -2.9 ABC transporter ATP-binding protein compare
MMP_RS04125 -1.2 -1.4 TetR/AcrR family transcriptional regulator compare
MMP_RS06105 -1.2 -4.3 hydrogenase maturation peptidase HycI compare
MMP_RS07955 -1.2 -2.1 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS01525 -1.2 -1.0 nucleoside-diphosphate kinase compare
MMP_RS08830 -1.2 -3.5 GTP-binding protein compare
MMP_RS01725 -1.2 -1.7 class I SAM-dependent methyltransferase family protein compare
MMP_RS01915 -1.2 -4.8 DUF354 domain-containing protein compare
MMP_RS09055 -1.2 -0.6 CAP domain-containing protein compare
MMP_RS01955 -1.2 -1.3 hypothetical protein compare
MMP_RS08820 -1.2 -2.4 hypothetical protein compare
MMP_RS04255 -1.2 -2.8 coenzyme F420 hydrogenase subunit beta compare
MMP_RS01445 -1.2 -2.2 hypothetical protein compare
MMP_RS04870 -1.1 -2.0 TIGR02253 family HAD-type hydrolase compare
MMP_RS04090 -1.1 -1.2 hypothetical protein compare
MMP_RS09045 -1.1 -5.8 class III signal peptide-containing protein compare
MMP_RS06980 -1.1 -2.7 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS06285 -1.1 -1.3 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS03205 -1.1 -0.8 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS04290 -1.1 -2.6 4Fe-4S binding protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress Nitrofurantoin in Methanococcus maripaludis S2

For stress Nitrofurantoin across organisms