Experiment set12S346 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS00695		-2.9	-1.4	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS07845		-2.4	-4.0	LL-diaminopimelate aminotransferase
MMP_RS03445		-2.3	-1.4	methanogenesis marker 17 protein
MMP_RS06840		-2.2	-1.8	DNA-directed RNA polymerase subunit N
MMP_RS07355		-1.5	-1.2	transcription factor S
MMP_RS07630		-1.3	-1.2	ATP-binding cassette domain-containing protein
MMP_RS08300		-1.3	-1.5	metal-sulfur cluster assembly factor
MMP_RS01020		-1.2	-1.3	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS03080		-1.1	-2.8	universal stress protein
MMP_RS06600		-1.1	-1.5	class III signal peptide-containing protein
MMP_RS08165		-1.0	-2.2	phosphoglycerate dehydrogenase
MMP_RS02900		-1.0	-0.6	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS00060		-1.0	-1.3	3-dehydroquinate synthase II
MMP_RS02300		-1.0	-3.0	NAD(P)H-dependent oxidoreductase
MMP_RS01075		-1.0	-2.1	hypothetical protein
MMP_RS00300		-0.9	-0.7	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS05835		-0.9	-0.8	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS06590		-0.9	-1.7	GNAT family N-acetyltransferase
MMP_RS06395		-0.9	-2.3	ThiF family adenylyltransferase
MMP_RS00730		-0.9	-2.0	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS07860		-0.9	-0.5	hypothetical protein
MMP_RS02310		-0.8	-1.4	RimK-like ATPgrasp N-terminal domain-containing protein
MMP_RS01960		-0.8	-0.9	hypothetical protein
MMP_RS08940		-0.8	-1.1	MetS family NSS transporter small subunit
MMP_RS01100		-0.8	-1.2	ABC transporter ATP-binding protein
MMP_RS03535		-0.8	-2.0	helix-turn-helix transcriptional regulator
MMP_RS03125		-0.8	-2.7	cell division ATPase MinD
MMP_RS02720		-0.8	-1.6	molybdate ABC transporter substrate-binding protein
MMP_RS05830		-0.8	-1.3	peptidyl-prolyl cis-trans isomerase
MMP_RS06870		-0.7	-1.9	DedA family protein
MMP_RS03550		-0.7	-0.9	DUF2124 domain-containing protein
MMP_RS08195		-0.7	-3.4	hypothetical protein
MMP_RS01545		-0.7	-0.9	CBS domain-containing protein
MMP_RS01180		-0.7	-1.8	XTP/dITP diphosphatase
MMP_RS08350		-0.7	-0.8	hypothetical protein
MMP_RS06515		-0.7	-1.9	UPF0489 family protein
MMP_RS02410		-0.7	-1.4	ABC transporter substrate-binding protein
MMP_RS06900		-0.7	-1.3	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS06610		-0.7	-1.7	DUF2334 domain-containing protein
MMP_RS05910		-0.7	-1.9	cell division ATPase MinD
MMP_RS07730		-0.7	-1.1	pyruvate synthase subunit beta
MMP_RS02495		-0.6	-1.1	hypothetical protein
MMP_RS01110		-0.6	-1.9	FmdE family protein
MMP_RS05850		-0.6	-1.2	Ldh family oxidoreductase
MMP_RS08860		-0.6	-2.1	MinD/ParA family protein
MMP_RS08370		-0.6	-0.4	cation:proton antiporter subunit C
MMP_RS07560		-0.6	-2.4	prefoldin subunit alpha
MMP_RS00295		-0.6	-1.4	gamma carbonic anhydrase family protein
MMP_RS07755		-0.6	-0.7	DUF555 domain-containing protein
MMP_RS06885		-0.6	-1.1	50S ribosome-binding GTPase
MMP_RS01755		-0.6	-1.0	DUF2097 domain-containing protein
MMP_RS08650		-0.6	-1.5	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS02145		-0.6	-2.2	winged helix-turn-helix transcriptional regulator
MMP_RS02190		-0.6	-1.4	sulfopyruvate decarboxylase subunit alpha
MMP_RS06355		-0.6	-1.3	molybdenum cofactor biosynthesis protein MoaE
MMP_RS01290		-0.6	-3.1	class III signal peptide-containing protein
MMP_RS02605		-0.6	-0.5	MotA/TolQ/ExbB proton channel family protein
MMP_RS00675		-0.6	-0.5	nitroreductase family protein
MMP_RS01435		-0.6	-2.2	DMT family transporter
MMP_RS05985		-0.5	-1.5	hypothetical protein
MMP_RS02930		-0.5	-1.4	class I SAM-dependent methyltransferase
MMP_RS08600		-0.5	-0.7	flagellar protein D
MMP_RS08580		-0.5	-1.4	flagellin
MMP_RS00750		-0.5	-1.0	fumarate hydratase
MMP_RS01285		-0.5	-2.3	hypothetical protein
MMP_RS08635		-0.5	-0.6	UbiA family prenyltransferase
MMP_RS08590		-0.5	-1.5	flagellin
MMP_RS06575		-0.5	-1.1	fluoride efflux transporter CrcB
MMP_RS06285		-0.5	-0.8	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS08615		-0.5	-1.3	flagellar protein G
MMP_RS06915		-0.5	-1.4	metallophosphoesterase
MMP_RS00720		-0.5	-2.0	metal-dependent hydrolase
MMP_RS05795		-0.5	-1.7	redox-regulated ATPase YchF
MMP_RS06720		-0.5	-3.7	response regulator transcription factor
MMP_RS06525		-0.5	-0.7	YciI family protein
MMP_RS01275		-0.5	-2.1	class III signal peptide-containing protein
MMP_RS01890		-0.5	-1.3	nucleotide sugar dehydrogenase
MMP_RS01305		-0.5	-4.2	hypothetical protein
MMP_RS01295		-0.5	-2.4	hypothetical protein
MMP_RS05980		-0.5	-2.7	ferritin
MMP_RS02965		-0.5	-1.9	carboxymuconolactone decarboxylase family protein
MMP_RS07580		-0.5	-1.1	DUF356 domain-containing protein
MMP_RS00240		-0.5	-4.1	type II secretion system F family protein
MMP_RS06375		-0.5	-2.3	ATP-dependent sacrificial sulfur transferase LarE
MMP_RS01660		-0.5	-1.2	hypothetical protein
MMP_RS06990		-0.5	-1.7	CatB-related O-acetyltransferase
MMP_RS04125		-0.5	-1.9	TetR/AcrR family transcriptional regulator
MMP_RS01270		-0.4	-3.5	prepilin peptidase
MMP_RS08855		-0.4	-3.1	hypothetical protein
MMP_RS02815		-0.4	-1.2	hypothetical protein
MMP_RS03780		-0.4	-1.5	4Fe-4S binding protein
MMP_RS03305		-0.4	-2.7	winged helix-turn-helix domain-containing protein
MMP_RS06665		-0.4	-2.6	glycogen/starch synthase
MMP_RS06715		-0.4	-2.9	cache domain-containing protein
MMP_RS03960		-0.4	-0.6	hypothetical protein
MMP_RS01830		-0.4	-0.4	tRNA-Val
MMP_RS01085		-0.4	-1.0	hypothetical protein
MMP_RS04195		-0.4	-1.0	flavodoxin
MMP_RS01310		-0.4	-2.9	hypothetical protein
MMP_RS05965		-0.4	-1.2	carboxymuconolactone decarboxylase family protein
MMP_RS07345		-0.4	-1.6	glycine synthesis protein GlyXL (from data)
MMP_RS02240		-0.4	-1.0	methanogenesis marker 7 protein
MMP_RS02545		-0.4	-1.9	hypothetical protein
MMP_RS05975		-0.4	-1.9	hypothetical protein
MMP_RS03235		-0.4	-1.3	tRNA pseudouridine(13) synthase TruD
MMP_RS06735		-0.4	-1.1	class I SAM-dependent rRNA methyltransferase
MMP_RS01965		-0.4	-1.0	DUF1616 domain-containing protein
MMP_RS01120		-0.4	-1.4	permease
MMP_RS01265		-0.4	-1.2	hypothetical protein
MMP_RS01280		-0.4	-3.0	DUF515 domain-containing protein
MMP_RS08215		-0.4	-0.9	DUF483 domain-containing protein
MMP_RS01315		-0.4	-3.5	DUF2341 domain-containing protein
MMP_RS06095		-0.4	-2.5	ABC transporter ATP-binding protein
MMP_RS02175		-0.4	-0.3	DUF1611 domain-containing protein
MMP_RS06055		-0.4	-2.1	peroxiredoxin
MMP_RS03620		-0.4	-2.0	hypothetical protein
MMP_RS08310		-0.4	-0.8	TMEM165/GDT1 family protein
MMP_RS03395		-0.4	-1.5	hypothetical protein
MMP_RS08980		-0.4	-1.9	hypothetical protein
MMP_RS07445		-0.4	-2.2	helix-turn-helix domain-containing protein
MMP_RS00905		-0.4	-1.2	phenylacetate--CoA ligase
MMP_RS08095		-0.4	-1.4	dethiobiotin synthase
MMP_RS00530		-0.4	-1.6	tRNA pseudouridine(54/55) synthase Pus10
MMP_RS02745		-0.4	-0.5	hypothetical protein
MMP_RS04945		-0.4	-1.2	hypothetical protein
MMP_RS04060		-0.4	-1.6	hypothetical protein
MMP_RS06625		-0.4	-0.9	DNA primase
MMP_RS01465		-0.4	-0.7	hypothetical protein
MMP_RS07955		-0.4	-1.2	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS08235		-0.4	-1.3	hypothetical protein
MMP_RS03565		-0.4	-1.6	uracil phosphoribosyltransferase
MMP_RS00125		-0.4	-0.6	DUF2798 domain-containing protein
MMP_RS05995		-0.4	-1.8	FprA family A-type flavoprotein
MMP_RS03390		-0.4	-1.6	malate dehydrogenase
MMP_RS03280		-0.4	-1.5	pyridoxamine 5'-phosphate oxidase family protein
MMP_RS00245		-0.3	-2.9	type II secretion system F family protein
MMP_RS02010		-0.3	-1.6	PHP domain-containing protein
MMP_RS04045		-0.3	-1.7	hypothetical protein
MMP_RS05990		-0.3	-1.1	DsrE family protein
MMP_RS07620		-0.3	-1.4	energy-coupling factor ABC transporter substrate-binding protein
MMP_RS08835		-0.3	-2.1	H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
MMP_RS08430		-0.3	-1.5	HAD family hydrolase
MMP_RS02550		-0.3	-1.3	helix-turn-helix transcriptional regulator
MMP_RS06460		-0.3	-0.7	pyrimidine dimer DNA glycosylase/endonuclease V
MMP_RS01445		-0.3	-1.3	hypothetical protein
MMP_RS00725		-0.3	-1.9	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS07960		-0.3	-2.2	sugar phosphate isomerase/epimerase
MMP_RS04285		-0.3	-1.4	Ni/Fe hydrogenase subunit alpha
MMP_RS05770		-0.3	-1.5	YkgJ family cysteine cluster protein
MMP_RS02850		-0.3	-1.8	hypothetical protein
MMP_RS05425		-0.3	-1.2	monovalent cation/H+ antiporter complex subunit F
MMP_RS05960		-0.3	-1.9	CoB--CoM heterodisulfide reductase subunit B
MMP_RS06895		-0.3	-0.6	selenocysteine-specific translation elongation factor
MMP_RS04850		-0.3	-2.2	UPF0254 family protein
MMP_RS08460		-0.3	-0.8	proteasome-activating nucleotidase
MMP_RS04335		-0.3	-1.8	GTP-binding protein
MMP_RS08105		-0.3	-1.4	6-carboxyhexanoate--CoA ligase
MMP_RS04605		-0.3	-0.9	cobalt ECF transporter T component CbiQ
MMP_RS08285		-0.3	-1.4	serine/threonine protein kinase
MMP_RS01470		-0.3	-0.7	ATP-binding cassette domain-containing protein
MMP_RS08455		-0.3	-0.9	multiprotein bridging factor aMBF1
MMP_RS02530		-0.3	-1.8	type II toxin-antitoxin system mRNA interferase toxin RelE/StbE family
MMP_RS05810		-0.3	-2.0	archaeosortase family protein ArtE
MMP_RS03900		-0.3	-1.6	minichromosome maintenance protein MCM
MMP_RS03425		-0.3	-1.2	hypothetical protein
MMP_RS07710		-0.3	-1.1	cell division protein FtsZ
MMP_RS05925		-0.3	-0.9	small nuclear ribonucleoprotein
MMP_RS08830		-0.3	-1.5	GTP-binding protein
MMP_RS00965		-0.3	-1.0	hypothetical protein
MMP_RS00545		-0.3	-0.6	XRE family transcriptional regulator
MMP_RS04215		-0.3	-1.2	nickel pincer cofactor biosynthesis protein LarB
MMP_RS01195		-0.3	-0.4	metalloregulator ArsR/SmtB family transcription factor
MMP_RS03120		-0.3	-1.1	hypothetical protein
MMP_RS08200		-0.3	-2.1	archaeosine synthase subunit alpha
MMP_RS00140		-0.3	-1.5	DUF192 domain-containing protein
MMP_RS06225		-0.3	-1.6	DNA double-strand break repair nuclease NurA
MMP_RS05020		-0.3	-1.1	hypothetical protein
MMP_RS08720		-0.3	-0.3	4Fe-4S binding protein
MMP_RS05295		-0.3	-1.3	minichromosome maintenance protein MCM
MMP_RS02425		-0.3	-1.4	hypothetical protein
MMP_RS04815		-0.3	-1.2	chemotaxis protein CheD
MMP_RS07805		-0.3	-1.4	ABC transporter permease
MMP_RS08770		-0.3	-1.4	hypothetical protein
MMP_RS02730		-0.3	-1.8	ModD protein
MMP_RS08760		-0.3	-0.6	hypothetical protein
MMP_RS02955		-0.3	-0.9	DJ-1/PfpI family protein
MMP_RS06765		-0.3	-1.3	flap endonuclease-1
MMP_RS05160		-0.3	-1.5	cupredoxin family copper-binding protein
MMP_RS04740		-0.3	-0.8	DUF473 domain-containing protein
MMP_RS08660		-0.3	-1.4	DHH family phosphoesterase
MMP_RS03330		-0.3	-2.0	rubrerythrin family protein
MMP_RS01925		-0.3	-1.4	DUF1616 domain-containing protein
MMP_RS03065		-0.3	-0.9	AzlC family ABC transporter permease
MMP_RS01805		-0.3	-1.3	NUDIX hydrolase
MMP_RS08175		-0.3	-1.2	7-cyano-7-deazaguanine synthase
MMP_RS00555		-0.3	-1.5	MFS transporter
MMP_RS03495		-0.3	-1.3	Na/Pi cotransporter family protein
MMP_RS01045		-0.3	-1.2	diphthamide biosynthesis enzyme Dph2
MMP_RS02985		-0.3	-0.9	hypothetical protein
MMP_RS04100		-0.3	-1.1	hypothetical protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Hydroxylamine hydrochloride across organisms