Experiment set12S345 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete dimetridazole 0.000833333333333333 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS08435 -8.1 -1.4 Era-like GTP-binding protein compare
MMP_RS03600 -7.0 -1.4 triose-phosphate isomerase compare
MMP_RS07390 -6.9 -1.5 cell division protein FtsZ compare
MMP_RS06400 -6.6 -1.0 4Fe-4S binding protein compare
MMP_RS05550 -5.7 -0.5 cation:proton antiporter compare
MMP_RS00300 -5.6 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS07005 -5.0 -0.4 4Fe-4S binding protein compare
MMP_RS05920 -5.0 -0.4 50S ribosomal protein L37e compare
MMP_RS01755 -4.8 -0.8 DUF2097 domain-containing protein compare
MMP_RS00515 -4.8 -0.6 DUF655 domain-containing protein compare
MMP_RS00695 -4.7 -0.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01890 -4.7 -4.1 nucleotide sugar dehydrogenase compare
MMP_RS06730 -4.5 -1.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS08715 -4.5 -1.3 formylmethanofuran dehydrogenase subunit B compare
MMP_RS04090 -4.3 -2.0 hypothetical protein compare
MMP_RS04890 -4.2 -0.5 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS02145 -4.1 -7.8 winged helix-turn-helix transcriptional regulator compare
MMP_RS06895 -4.1 -1.3 selenocysteine-specific translation elongation factor compare
MMP_RS03580 -4.1 -2.6 signal recognition particle-docking protein FtsY compare
MMP_RS08720 -4.1 -1.2 4Fe-4S binding protein compare
MMP_RS06020 -4.0 -3.5 archaeoflavoprotein AfpA compare
MMP_RS07635 -4.0 -6.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08440 -3.9 -2.3 cell division protein SepF compare
MMP_RS00040 -3.9 -4.7 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS01610 -3.8 -2.5 hypothetical protein compare
MMP_RS01955 -3.8 -2.2 hypothetical protein compare
MMP_RS06630 -3.8 -0.7 UPF0058 family protein compare
MMP_RS06230 -3.7 -1.9 helix-turn-helix domain-containing protein compare
MMP_RS06350 -3.7 -5.2 HesA/MoeB/ThiF family protein compare
MMP_RS05345 -3.6 -6.3 hypothetical protein compare
MMP_RS03435 -3.6 -1.4 ketol-acid reductoisomerase compare
MMP_RS01880 -3.6 -6.3 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS07630 -3.6 -1.3 ATP-binding cassette domain-containing protein compare
MMP_RS07845 -3.5 -2.0 LL-diaminopimelate aminotransferase compare
MMP_RS01175 -3.5 -3.3 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06725 -3.5 -7.8 hypothetical protein compare
MMP_RS00520 -3.4 -1.2 RNA polymerase Rpb4 family protein compare
MMP_RS05845 -3.3 -1.4 tRNA-intron lyase compare
MMP_RS08855 -3.3 -8.8 hypothetical protein compare
MMP_RS08820 -3.3 -4.7 hypothetical protein compare
MMP_RS04710 -3.2 -1.4 hypothetical protein compare
MMP_RS08650 -3.2 -2.9 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS06625 -3.2 -1.3 DNA primase compare
MMP_RS08675 -3.1 -2.4 class III signal peptide-containing protein compare
MMP_RS07330 -3.1 -17.3 membrane protein compare
MMP_RS07075 -3.1 -3.3 phosphomannomutase/phosphoglucomutase compare
MMP_RS01800 -3.1 -3.0 TIGR00303 family protein compare
MMP_RS03035 -3.0 -2.6 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS07555 -3.0 -0.5 monovalent cation/H+ antiporter subunit E compare
MMP_RS00685 -3.0 -2.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS04900 -3.0 -17.3 hypothetical protein compare
MMP_RS06285 -3.0 -1.6 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS05635 -3.0 -8.4 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS08210 -2.9 -1.6 phosphatidylglycerophosphatase A compare
MMP_RS01295 -2.9 -10.2 hypothetical protein compare
MMP_RS00240 -2.9 -15.6 type II secretion system F family protein compare
MMP_RS01545 -2.9 -0.8 CBS domain-containing protein compare
MMP_RS03025 -2.9 -4.0 molybdenum cofactor guanylyltransferase compare
MMP_RS00245 -2.9 -18.2 type II secretion system F family protein compare
MMP_RS01265 -2.9 -2.1 hypothetical protein compare
MMP_RS01270 -2.8 -12.3 prepilin peptidase compare
MMP_RS07605 -2.8 -2.5 diadenylate cyclase compare
MMP_RS06035 -2.8 -8.4 glycosyltransferase family 2 protein compare
MMP_RS03640 -2.8 -2.6 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS05580 -2.8 -13.9 glycosyltransferase compare
MMP_RS01280 -2.8 -15.9 DUF515 domain-containing protein compare
MMP_RS07435 -2.8 -1.2 GMP synthase subunit A compare
MMP_RS06315 -2.8 -0.6 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS01005 -2.8 -0.9 riboflavin synthase compare
MMP_RS01285 -2.7 -8.4 hypothetical protein compare
MMP_RS00250 -2.7 -15.2 Flp pilus assembly complex ATPase component TadA compare
MMP_RS07755 -2.7 -0.9 DUF555 domain-containing protein compare
MMP_RS02470 -2.7 -1.2 helix-turn-helix transcriptional regulator compare
MMP_RS03400 -2.7 -1.8 archease compare
MMP_RS03125 -2.7 -4.6 cell division ATPase MinD compare
MMP_RS01380 -2.7 -2.8 PHP domain-containing protein compare
MMP_RS01290 -2.6 -9.7 class III signal peptide-containing protein compare
MMP_RS01875 -2.6 -7.3 N-acetyltransferase compare
MMP_RS00810 -2.6 -5.3 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS08745 -2.6 -5.1 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS03960 -2.6 -0.9 hypothetical protein compare
MMP_RS07710 -2.5 -5.5 cell division protein FtsZ compare
MMP_RS03080 -2.5 -2.7 universal stress protein compare
MMP_RS08860 -2.5 -4.8 MinD/ParA family protein compare
MMP_RS01905 -2.5 -9.3 glycosyltransferase compare
MMP_RS01885 -2.5 -4.5 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS00110 -2.5 -2.3 hypothetical protein compare
MMP_RS06340 -2.5 -6.1 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS01305 -2.5 -14.5 hypothetical protein compare
MMP_RS00985 -2.4 -4.4 CDC48 family AAA ATPase compare
MMP_RS01310 -2.4 -13.1 hypothetical protein compare
MMP_RS01315 -2.4 -16.1 DUF2341 domain-containing protein compare
MMP_RS07875 -2.3 -4.1 hypothetical protein compare
MMP_RS03700 -2.3 -6.0 sodium:proton antiporter compare
MMP_RS06940 -2.3 -3.0 polyprenyl diphosphate synthase compare
MMP_RS07750 -2.3 -4.3 DUF357 domain-containing protein compare
MMP_RS01075 -2.3 -1.4 hypothetical protein compare
MMP_RS00915 -2.3 -5.0 DUF116 domain-containing protein compare
MMP_RS01085 -2.3 -1.3 hypothetical protein compare
MMP_RS07380 -2.3 -1.4 transcription elongation factor Spt5 compare
MMP_RS08195 -2.3 -7.7 hypothetical protein compare
MMP_RS02235 -2.3 -7.7 CBS domain-containing protein compare
MMP_RS06295 -2.2 -5.3 methanogenesis marker 14 protein compare
MMP_RS00315 -2.2 -4.5 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01900 -2.2 -6.9 hypothetical protein compare
MMP_RS03315 -2.2 -0.8 ferrous iron transport protein A compare
MMP_RS04780 -2.2 -2.1 ribonuclease P compare
MMP_RS08645 -2.1 -4.4 UPF0179 family protein compare
MMP_RS02195 -2.1 -1.7 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS08785 -2.1 -0.6 RNA-protein complex protein Nop10 compare
MMP_RS01385 -2.1 -0.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS07820 -2.1 -2.2 UPF0104 family protein compare
MMP_RS05250 -2.1 -2.8 NFYB/HAP3 family transcription factor subunit compare
MMP_RS06120 -2.1 -1.1 UPF0147 family protein compare
MMP_RS08940 -2.1 -0.9 MetS family NSS transporter small subunit compare
MMP_RS01275 -2.0 -5.2 class III signal peptide-containing protein compare
MMP_RS06395 -2.0 -2.2 ThiF family adenylyltransferase compare
MMP_RS03475 -2.0 -0.4 hypothetical protein compare
MMP_RS01225 -2.0 -3.2 DUF5379 domain-containing protein compare
MMP_RS06925 -2.0 -1.7 ribonuclease VapC4 compare
MMP_RS06980 -2.0 -3.9 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS04955 -2.0 -4.9 DNA topoisomerase I compare
MMP_RS04685 -2.0 -1.9 DUF126 domain-containing protein compare
MMP_RS06900 -2.0 -2.0 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS07695 -2.0 -4.6 DUF3236 domain-containing protein compare
MMP_RS04585 -2.0 -5.1 AIR synthase related protein compare
MMP_RS07350 -2.0 -0.8 preprotein translocase subunit Sec61beta compare
MMP_RS04775 -2.0 -2.0 adenosylhomocysteinase compare
MMP_RS01725 -1.9 -2.3 class I SAM-dependent methyltransferase family protein compare
MMP_RS05295 -1.9 -5.3 minichromosome maintenance protein MCM compare
MMP_RS01830 -1.9 -0.9 tRNA-Val compare
MMP_RS06670 -1.9 -3.3 glucose-6-phosphate isomerase compare
MMP_RS03015 -1.9 -7.1 GTP 3' 8-cyclase MoaA compare
MMP_RS01895 -1.9 -7.1 flippase compare
MMP_RS08635 -1.9 -1.1 UbiA family prenyltransferase compare
MMP_RS01925 -1.9 -4.2 DUF1616 domain-containing protein compare
MMP_RS05265 -1.9 -1.4 2-isopropylmalate synthase compare
MMP_RS05430 -1.9 -4.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS02800 -1.9 -5.0 nucleotidyltransferase domain-containing protein compare
MMP_RS09045 -1.9 -8.7 class III signal peptide-containing protein compare
MMP_RS04720 -1.9 -1.9 DedA family protein compare
MMP_RS07625 -1.9 -1.7 cobalt ECF transporter T component CbiQ compare
MMP_RS05930 -1.8 -1.4 3-isopropylmalate dehydratase large subunit compare
MMP_RS05515 -1.8 -3.9 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS08460 -1.8 -1.4 proteasome-activating nucleotidase compare
MMP_RS09055 -1.8 -0.7 CAP domain-containing protein compare
MMP_RS00305 -1.8 -1.0 phosphoribosyl-ATP diphosphatase compare
MMP_RS01665 -1.8 -2.1 DUF2111 domain-containing protein compare
MMP_RS07730 -1.8 -1.3 pyruvate synthase subunit beta compare
MMP_RS06355 -1.7 -1.5 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS02930 -1.7 -1.9 class I SAM-dependent methyltransferase compare
MMP_RS03140 -1.7 -6.6 hypothetical protein compare
MMP_RS00310 -1.7 -6.1 CBS domain-containing protein compare
MMP_RS05640 -1.7 -3.3 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS04850 -1.7 -7.9 UPF0254 family protein compare
MMP_RS01220 -1.7 -4.4 hypothetical protein compare
MMP_RS07615 -1.6 -4.0 energy-coupling factor ABC transporter permease compare
MMP_RS05245 -1.6 -5.9 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS01960 -1.6 -0.6 hypothetical protein compare
MMP_RS06110 -1.6 -2.1 ATP-dependent protease LonB compare
MMP_RS08155 -1.6 -3.2 hypothetical protein compare
MMP_RS00320 -1.6 -1.0 class I SAM-dependent methyltransferase compare
MMP_RS01915 -1.6 -5.7 DUF354 domain-containing protein compare
MMP_RS04485 -1.6 -6.1 putative beta-lysine N-acetyltransferase compare
MMP_RS08600 -1.6 -1.2 flagellar protein D compare
MMP_RS05425 -1.6 -3.0 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS02240 -1.6 -1.4 methanogenesis marker 7 protein compare
MMP_RS01975 -1.6 -6.0 hypothetical protein compare
MMP_RS07620 -1.6 -3.0 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS07575 -1.5 -2.6 RNA ligase partner protein compare
MMP_RS05355 -1.5 -0.5 hypothetical protein compare
MMP_RS06105 -1.5 -4.8 hydrogenase maturation peptidase HycI compare
MMP_RS07200 -1.5 -3.7 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06885 -1.5 -1.5 50S ribosome-binding GTPase compare
MMP_RS07425 -1.5 -2.9 GTP-binding protein compare
MMP_RS01700 -1.5 -0.6 dihydroxy-acid dehydratase compare
MMP_RS08790 -1.5 -1.1 translation initiation factor IF-2 subunit alpha compare
MMP_RS00730 -1.4 -3.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS06130 -1.4 -1.5 peptidylprolyl isomerase compare
MMP_RS05540 -1.4 -1.9 hypothetical protein compare
MMP_RS01365 -1.4 -1.5 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS05020 -1.4 -1.4 hypothetical protein compare
MMP_RS01020 -1.4 -0.6 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS02405 -1.4 -3.0 hypothetical protein compare
MMP_RS01910 -1.4 -4.3 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS02345 -1.4 -1.8 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS05445 -1.4 -3.7 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS03445 -1.3 -0.5 methanogenesis marker 17 protein compare
MMP_RS01325 -1.3 -0.8 dihydroneopterin aldolase family protein compare
MMP_RS03145 -1.3 -2.7 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS04125 -1.3 -1.7 TetR/AcrR family transcriptional regulator compare
MMP_RS01500 -1.3 -1.2 CBS domain-containing protein compare
MMP_RS06015 -1.3 -2.6 flavodoxin family protein compare
MMP_RS07090 -1.3 -4.4 tRNA (adenine-N1)-methyltransferase compare
MMP_RS01840 -1.3 -2.9 TIGR00289 family protein compare
MMP_RS01970 -1.3 -4.3 TIGR04279 domain-containing protein compare
MMP_RS00720 -1.3 -2.4 metal-dependent hydrolase compare
MMP_RS01920 -1.3 -4.9 glycosyltransferase family 2 protein compare
MMP_RS02355 -1.2 -1.3 30S ribosomal protein S27ae compare
MMP_RS08165 -1.2 -1.0 phosphoglycerate dehydrogenase compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Dimetridazole across organisms