Experiment set12S333 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete dimetridazole 0.00833333333333333 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS08300 -5.7 -1.0 metal-sulfur cluster assembly factor compare
MMP_RS08210 -5.6 -1.7 phosphatidylglycerophosphatase A compare
MMP_RS08720 -5.5 -1.1 4Fe-4S binding protein compare
MMP_RS05550 -5.4 -0.5 cation:proton antiporter compare
MMP_RS07005 -4.9 -0.5 4Fe-4S binding protein compare
MMP_RS08715 -4.3 -1.4 formylmethanofuran dehydrogenase subunit B compare
MMP_RS03960 -4.2 -0.9 hypothetical protein compare
MMP_RS01960 -4.2 -0.8 hypothetical protein compare
MMP_RS08635 -4.0 -1.3 UbiA family prenyltransferase compare
MMP_RS03475 -3.8 -0.5 hypothetical protein compare
MMP_RS07735 -3.8 -0.5 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS03435 -3.6 -1.5 ketol-acid reductoisomerase compare
MMP_RS00110 -3.4 -2.7 hypothetical protein compare
MMP_RS01545 -3.3 -0.8 CBS domain-containing protein compare
MMP_RS00695 -3.0 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00985 -2.7 -4.4 CDC48 family AAA ATPase compare
MMP_RS07630 -2.7 -1.2 ATP-binding cassette domain-containing protein compare
MMP_RS01175 -2.7 -3.2 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06120 -2.7 -1.4 UPF0147 family protein compare
MMP_RS07635 -2.6 -7.0 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06350 -2.6 -4.3 HesA/MoeB/ThiF family protein compare
MMP_RS06355 -2.6 -2.1 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01610 -2.5 -2.2 hypothetical protein compare
MMP_RS00300 -2.5 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS08820 -2.5 -4.7 hypothetical protein compare
MMP_RS07555 -2.5 -0.5 monovalent cation/H+ antiporter subunit E compare
MMP_RS07545 -2.4 -0.8 HTH domain-containing protein compare
MMP_RS03445 -2.4 -0.7 methanogenesis marker 17 protein compare
MMP_RS01830 -2.3 -1.1 tRNA-Val compare
MMP_RS03400 -2.3 -1.9 archease compare
MMP_RS05845 -2.3 -1.3 tRNA-intron lyase compare
MMP_RS01005 -2.2 -0.8 riboflavin synthase compare
MMP_RS01385 -2.2 -0.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS04900 -2.2 -16.3 hypothetical protein compare
MMP_RS02800 -2.2 -4.5 nucleotidyltransferase domain-containing protein compare
MMP_RS07845 -2.2 -2.0 LL-diaminopimelate aminotransferase compare
MMP_RS06295 -2.2 -5.7 methanogenesis marker 14 protein compare
MMP_RS05295 -2.1 -9.8 minichromosome maintenance protein MCM compare
MMP_RS08195 -2.1 -6.9 hypothetical protein compare
MMP_RS07750 -2.0 -4.2 DUF357 domain-containing protein compare
MMP_RS01270 -2.0 -12.2 prepilin peptidase compare
MMP_RS08855 -2.0 -7.3 hypothetical protein compare
MMP_RS01800 -2.0 -2.7 TIGR00303 family protein compare
MMP_RS01310 -2.0 -12.5 hypothetical protein compare
MMP_RS01725 -2.0 -2.3 class I SAM-dependent methyltransferase family protein compare
MMP_RS07605 -2.0 -2.3 diadenylate cyclase compare
MMP_RS07380 -2.0 -1.4 transcription elongation factor Spt5 compare
MMP_RS03080 -2.0 -1.9 universal stress protein compare
MMP_RS00240 -2.0 -10.4 type II secretion system F family protein compare
MMP_RS06020 -2.0 -3.1 archaeoflavoprotein AfpA compare
MMP_RS01220 -1.9 -5.4 hypothetical protein compare
MMP_RS08675 -1.9 -1.9 class III signal peptide-containing protein compare
MMP_RS04780 -1.9 -2.0 ribonuclease P compare
MMP_RS01295 -1.9 -7.7 hypothetical protein compare
MMP_RS05635 -1.9 -7.4 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS01755 -1.9 -0.8 DUF2097 domain-containing protein compare
MMP_RS01285 -1.9 -8.2 hypothetical protein compare
MMP_RS06035 -1.9 -6.7 glycosyltransferase family 2 protein compare
MMP_RS01305 -1.9 -12.4 hypothetical protein compare
MMP_RS01500 -1.9 -1.4 CBS domain-containing protein compare
MMP_RS00040 -1.9 -5.2 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS03015 -1.8 -6.0 GTP 3' 8-cyclase MoaA compare
MMP_RS07575 -1.8 -3.0 RNA ligase partner protein compare
MMP_RS06485 -1.8 -0.6 zinc ribbon domain-containing protein compare
MMP_RS08860 -1.8 -3.6 MinD/ParA family protein compare
MMP_RS02145 -1.8 -5.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS01275 -1.8 -4.9 class III signal peptide-containing protein compare
MMP_RS08745 -1.8 -4.6 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS03315 -1.8 -0.6 ferrous iron transport protein A compare
MMP_RS01290 -1.7 -7.5 class III signal peptide-containing protein compare
MMP_RS07525 -1.7 -6.0 4Fe-4S binding protein compare
MMP_RS07600 -1.7 -1.2 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06625 -1.7 -1.2 DNA primase compare
MMP_RS02175 -1.7 -0.5 DUF1611 domain-containing protein compare
MMP_RS01265 -1.7 -1.8 hypothetical protein compare
MMP_RS06900 -1.7 -1.5 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS07075 -1.7 -3.1 phosphomannomutase/phosphoglucomutase compare
MMP_RS08790 -1.7 -1.0 translation initiation factor IF-2 subunit alpha compare
MMP_RS04685 -1.7 -2.0 DUF126 domain-containing protein compare
MMP_RS06315 -1.7 -0.5 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS07330 -1.7 -11.8 membrane protein compare
MMP_RS00250 -1.7 -9.6 Flp pilus assembly complex ATPase component TadA compare
MMP_RS00515 -1.6 -0.6 DUF655 domain-containing protein compare
MMP_RS03035 -1.6 -2.3 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS08595 -1.6 -0.7 flagellar protein C compare
MMP_RS05515 -1.6 -4.8 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS02235 -1.6 -6.3 CBS domain-containing protein compare
MMP_RS00520 -1.6 -1.0 RNA polymerase Rpb4 family protein compare
MMP_RS02195 -1.6 -2.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07420 -1.6 -3.9 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01325 -1.6 -0.9 dihydroneopterin aldolase family protein compare
MMP_RS04775 -1.6 -2.2 adenosylhomocysteinase compare
MMP_RS02470 -1.6 -0.9 helix-turn-helix transcriptional regulator compare
MMP_RS05815 -1.6 -1.1 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS01315 -1.6 -12.0 DUF2341 domain-containing protein compare
MMP_RS00810 -1.6 -4.1 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS06340 -1.5 -4.6 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS02340 -1.5 -1.3 DNA-directed RNA polymerase subunit E'' compare
MMP_RS05245 -1.5 -6.5 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS06290 -1.5 -3.0 DNA repair and recombination protein RadA compare
MMP_RS00245 -1.5 -9.8 type II secretion system F family protein compare
MMP_RS07390 -1.5 -1.5 cell division protein FtsZ compare
MMP_RS02345 -1.5 -2.3 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS05580 -1.5 -8.8 glycosyltransferase compare
MMP_RS05345 -1.5 -4.3 hypothetical protein compare
MMP_RS04585 -1.5 -6.1 AIR synthase related protein compare
MMP_RS01365 -1.5 -1.9 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS06630 -1.5 -0.4 UPF0058 family protein compare
MMP_RS03600 -1.5 -1.3 triose-phosphate isomerase compare
MMP_RS01280 -1.5 -8.9 DUF515 domain-containing protein compare
MMP_RS00725 -1.4 -4.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS07755 -1.4 -0.6 DUF555 domain-containing protein compare
MMP_RS03640 -1.4 -2.0 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01380 -1.4 -2.5 PHP domain-containing protein compare
MMP_RS04615 -1.4 -1.8 PDGLE domain-containing protein compare
MMP_RS06400 -1.4 -0.8 4Fe-4S binding protein compare
MMP_RS03245 -1.4 -2.5 DNA repair and recombination protein RadB compare
MMP_RS00895 -1.4 -2.1 hypothetical protein compare
MMP_RS08460 -1.4 -1.4 proteasome-activating nucleotidase compare
MMP_RS06895 -1.4 -0.8 selenocysteine-specific translation elongation factor compare
MMP_RS00720 -1.4 -5.2 metal-dependent hydrolase compare
MMP_RS07695 -1.4 -3.6 DUF3236 domain-containing protein compare
MMP_RS02355 -1.4 -1.6 30S ribosomal protein S27ae compare
MMP_RS02240 -1.4 -1.6 methanogenesis marker 7 protein compare
MMP_RS06230 -1.4 -1.4 helix-turn-helix domain-containing protein compare
MMP_RS01955 -1.4 -1.6 hypothetical protein compare
MMP_RS04090 -1.4 -1.5 hypothetical protein compare
MMP_RS01225 -1.4 -2.6 DUF5379 domain-containing protein compare
MMP_RS09045 -1.4 -6.8 class III signal peptide-containing protein compare
MMP_RS08600 -1.3 -1.4 flagellar protein D compare
MMP_RS03580 -1.3 -2.0 signal recognition particle-docking protein FtsY compare
MMP_RS07710 -1.3 -4.9 cell division protein FtsZ compare
MMP_RS01085 -1.3 -1.1 hypothetical protein compare
MMP_RS08660 -1.3 -3.6 DHH family phosphoesterase compare
MMP_RS08940 -1.3 -0.7 MetS family NSS transporter small subunit compare
MMP_RS03095 -1.3 -3.1 diphthine synthase compare
MMP_RS01900 -1.3 -5.2 hypothetical protein compare
MMP_RS05540 -1.3 -2.2 hypothetical protein compare
MMP_RS06885 -1.2 -1.6 50S ribosome-binding GTPase compare
MMP_RS02010 -1.2 -2.6 PHP domain-containing protein compare
MMP_RS06980 -1.2 -3.7 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS07875 -1.2 -2.7 hypothetical protein compare
MMP_RS06155 -1.2 -1.6 DUF4186 domain-containing protein compare
MMP_RS03700 -1.2 -3.7 sodium:proton antiporter compare
MMP_RS01885 -1.2 -3.3 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS07190 -1.2 -3.6 chromosome segregation protein SMC compare
MMP_RS09020 -1.2 -0.8 hypothetical protein compare
MMP_RS00315 -1.2 -2.9 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS04955 -1.1 -3.2 DNA topoisomerase I compare
MMP_RS01925 -1.1 -2.5 DUF1616 domain-containing protein compare
MMP_RS00730 -1.1 -2.6 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS07355 -1.1 -0.5 transcription factor S compare
MMP_RS01700 -1.1 -0.4 dihydroxy-acid dehydratase compare
MMP_RS03125 -1.1 -2.3 cell division ATPase MinD compare
MMP_RS08370 -1.1 -0.3 cation:proton antiporter subunit C compare
MMP_RS02545 -1.1 -2.0 hypothetical protein compare
MMP_RS06855 -1.1 -4.0 hypothetical protein compare
MMP_RS08440 -1.1 -0.9 cell division protein SepF compare
MMP_RS00850 -1.1 -2.2 TIGR01177 family methyltransferase compare
MMP_RS03025 -1.1 -2.4 molybdenum cofactor guanylyltransferase compare
MMP_RS06395 -1.1 -1.7 ThiF family adenylyltransferase compare
MMP_RS04850 -1.1 -6.3 UPF0254 family protein compare
MMP_RS00685 -1.1 -1.4 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07200 -1.1 -3.2 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS08360 -1.1 -1.6 hypothetical protein compare
MMP_RS05560 -1.0 -3.2 deoxyuridine 5'-triphosphate nucleotidohydrolase compare
MMP_RS01895 -1.0 -5.7 flippase compare
MMP_RS04710 -1.0 -0.9 hypothetical protein compare
MMP_RS02610 -1.0 -2.4 DUF2162 domain-containing protein compare
MMP_RS02245 -1.0 -1.3 hypothetical protein compare
MMP_RS01600 -1.0 -1.2 50S ribosomal protein L15e compare
MMP_RS04485 -1.0 -3.8 putative beta-lysine N-acetyltransferase compare
MMP_RS08350 -1.0 -0.4 hypothetical protein compare
MMP_RS07700 -1.0 -4.4 DUF1188 domain-containing protein compare
MMP_RS00140 -1.0 -2.9 DUF192 domain-containing protein compare
MMP_RS05535 -1.0 -1.8 hypothetical protein compare
MMP_RS01075 -1.0 -0.7 hypothetical protein compare
MMP_RS09055 -1.0 -0.5 CAP domain-containing protein compare
MMP_RS06525 -0.9 -0.5 YciI family protein compare
MMP_RS06725 -0.9 -2.7 hypothetical protein compare
MMP_RS01100 -0.9 -0.7 ABC transporter ATP-binding protein compare
MMP_RS06285 -0.9 -0.9 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS00310 -0.9 -3.2 CBS domain-containing protein compare
MMP_RS01875 -0.9 -3.2 N-acetyltransferase compare
MMP_RS07730 -0.9 -1.0 pyruvate synthase subunit beta compare
MMP_RS08645 -0.9 -2.7 UPF0179 family protein compare
MMP_RS07955 -0.9 -2.3 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS05460 -0.9 -3.5 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS01660 -0.9 -1.5 hypothetical protein compare
MMP_RS03485 -0.9 -2.0 TIGR00267 family protein compare
MMP_RS02930 -0.9 -1.3 class I SAM-dependent methyltransferase compare
MMP_RS06765 -0.9 -2.3 flap endonuclease-1 compare
MMP_RS03440 -0.9 -0.4 MoaD/ThiS family protein compare
MMP_RS02495 -0.9 -1.2 hypothetical protein compare
MMP_RS05865 -0.9 -0.8 hypothetical protein compare
MMP_RS00965 -0.9 -1.5 hypothetical protein compare
MMP_RS05965 -0.9 -1.0 carboxymuconolactone decarboxylase family protein compare
MMP_RS07540 -0.9 -1.8 CBS domain-containing protein compare
MMP_RS00305 -0.9 -0.7 phosphoribosyl-ATP diphosphatase compare
MMP_RS00115 -0.9 -3.6 radical SAM protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Dimetridazole across organisms