Experiment set12S325 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete 8-hydroxy-nitroquinolone 0.0166666666666667 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS05550 -6.1 -0.6 cation:proton antiporter compare
MMP_RS09020 -4.1 -1.7 hypothetical protein compare
MMP_RS05850 -3.6 -5.3 Ldh family oxidoreductase compare
MMP_RS05425 -3.5 -5.1 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06350 -3.4 -7.5 HesA/MoeB/ThiF family protein compare
MMP_RS08715 -3.4 -1.7 formylmethanofuran dehydrogenase subunit B compare
MMP_RS04710 -3.3 -2.1 hypothetical protein compare
MMP_RS06355 -3.3 -2.8 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS07635 -3.3 -8.8 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS04900 -3.2 -24.9 hypothetical protein compare
MMP_RS01175 -3.1 -5.4 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03080 -3.1 -3.3 universal stress protein compare
MMP_RS07005 -3.1 -0.6 4Fe-4S binding protein compare
MMP_RS02290 -3.0 -9.7 MBL fold metallo-hydrolase compare
MMP_RS06725 -3.0 -10.2 hypothetical protein compare
MMP_RS08210 -2.9 -2.3 phosphatidylglycerophosphatase A compare
MMP_RS02145 -2.9 -9.8 winged helix-turn-helix transcriptional regulator compare
MMP_RS07755 -2.9 -1.2 DUF555 domain-containing protein compare
MMP_RS07735 -2.8 -0.8 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS01265 -2.8 -3.8 hypothetical protein compare
MMP_RS01545 -2.8 -1.2 CBS domain-containing protein compare
MMP_RS04890 -2.7 -0.8 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01225 -2.7 -4.6 DUF5379 domain-containing protein compare
MMP_RS03640 -2.7 -3.8 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06120 -2.7 -2.0 UPF0147 family protein compare
MMP_RS01325 -2.6 -1.7 dihydroneopterin aldolase family protein compare
MMP_RS03435 -2.6 -1.7 ketol-acid reductoisomerase compare
MMP_RS08745 -2.6 -6.2 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS01610 -2.6 -3.5 hypothetical protein compare
MMP_RS08435 -2.6 -2.5 Era-like GTP-binding protein compare
MMP_RS01875 -2.6 -12.2 N-acetyltransferase compare
MMP_RS01885 -2.6 -8.2 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01900 -2.6 -13.5 hypothetical protein compare
MMP_RS03445 -2.6 -1.0 methanogenesis marker 17 protein compare
MMP_RS01575 -2.5 -6.2 aldolase compare
MMP_RS02875 -2.5 -9.5 chorismate pyruvate-lyase family protein compare
MMP_RS03250 -2.5 -4.4 MJ1244 family protein compare
MMP_RS03580 -2.5 -3.7 signal recognition particle-docking protein FtsY compare
MMP_RS07075 -2.5 -4.8 phosphomannomutase/phosphoglucomutase compare
MMP_RS06340 -2.4 -6.6 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07420 -2.4 -5.3 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01385 -2.4 -0.6 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS04850 -2.3 -15.6 UPF0254 family protein compare
MMP_RS07695 -2.3 -7.2 DUF3236 domain-containing protein compare
MMP_RS03315 -2.3 -0.9 ferrous iron transport protein A compare
MMP_RS01960 -2.3 -1.2 hypothetical protein compare
MMP_RS07390 -2.3 -2.4 cell division protein FtsZ compare
MMP_RS01890 -2.3 -5.3 nucleotide sugar dehydrogenase compare
MMP_RS03700 -2.3 -8.9 sodium:proton antiporter compare
MMP_RS02235 -2.3 -10.4 CBS domain-containing protein compare
MMP_RS00315 -2.3 -6.5 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01880 -2.3 -6.0 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01925 -2.3 -6.8 DUF1616 domain-containing protein compare
MMP_RS00730 -2.3 -4.3 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS05695 -2.3 -5.5 phospholipase D-like domain-containing protein compare
MMP_RS06295 -2.3 -7.2 methanogenesis marker 14 protein compare
MMP_RS00735 -2.2 -3.9 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS04685 -2.2 -2.2 DUF126 domain-containing protein compare
MMP_RS06625 -2.2 -1.6 DNA primase compare
MMP_RS07355 -2.2 -0.9 transcription factor S compare
MMP_RS06035 -2.2 -10.2 glycosyltransferase family 2 protein compare
MMP_RS01905 -2.2 -11.5 glycosyltransferase compare
MMP_RS01665 -2.2 -3.4 DUF2111 domain-containing protein compare
MMP_RS00725 -2.1 -8.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS07545 -2.1 -0.9 HTH domain-containing protein compare
MMP_RS03015 -2.1 -8.3 GTP 3' 8-cyclase MoaA compare
MMP_RS01745 -2.1 -6.1 AMP phosphorylase compare
MMP_RS01500 -2.1 -2.2 CBS domain-containing protein compare
MMP_RS01270 -2.1 -11.9 prepilin peptidase compare
MMP_RS07700 -2.1 -9.5 DUF1188 domain-containing protein compare
MMP_RS00985 -2.1 -5.2 CDC48 family AAA ATPase compare
MMP_RS05515 -2.1 -6.1 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06600 -2.1 -1.1 class III signal peptide-containing protein compare
MMP_RS02345 -2.0 -3.7 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS03600 -2.0 -2.3 triose-phosphate isomerase compare
MMP_RS05635 -2.0 -9.0 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS07710 -2.0 -6.3 cell division protein FtsZ compare
MMP_RS08300 -2.0 -1.1 metal-sulfur cluster assembly factor compare
MMP_RS06395 -2.0 -3.2 ThiF family adenylyltransferase compare
MMP_RS04720 -2.0 -2.4 DedA family protein compare
MMP_RS03400 -2.0 -2.6 archease compare
MMP_RS07955 -1.9 -5.2 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS03960 -1.9 -1.2 hypothetical protein compare
MMP_RS05580 -1.9 -12.2 glycosyltransferase compare
MMP_RS00040 -1.9 -6.0 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS06670 -1.9 -4.9 glucose-6-phosphate isomerase compare
MMP_RS07330 -1.9 -14.0 membrane protein compare
MMP_RS02240 -1.9 -3.0 methanogenesis marker 7 protein compare
MMP_RS05845 -1.9 -1.6 tRNA-intron lyase compare
MMP_RS06400 -1.8 -1.2 4Fe-4S binding protein compare
MMP_RS01380 -1.8 -4.7 PHP domain-containing protein compare
MMP_RS02800 -1.8 -5.1 nucleotidyltransferase domain-containing protein compare
MMP_RS01755 -1.8 -1.1 DUF2097 domain-containing protein compare
MMP_RS08635 -1.8 -1.7 UbiA family prenyltransferase compare
MMP_RS08675 -1.8 -2.9 class III signal peptide-containing protein compare
MMP_RS01005 -1.8 -1.1 riboflavin synthase compare
MMP_RS07845 -1.8 -2.7 LL-diaminopimelate aminotransferase compare
MMP_RS00300 -1.8 -0.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06020 -1.8 -3.7 archaeoflavoprotein AfpA compare
MMP_RS01800 -1.8 -3.4 TIGR00303 family protein compare
MMP_RS05925 -1.8 -2.4 small nuclear ribonucleoprotein compare
MMP_RS02195 -1.8 -3.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS03025 -1.8 -4.9 molybdenum cofactor guanylyltransferase compare
MMP_RS05640 -1.8 -3.9 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS00750 -1.7 -2.0 fumarate hydratase compare
MMP_RS01725 -1.7 -3.5 class I SAM-dependent methyltransferase family protein compare
MMP_RS01910 -1.7 -8.4 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS07380 -1.7 -1.5 transcription elongation factor Spt5 compare
MMP_RS01830 -1.7 -1.3 tRNA-Val compare
MMP_RS08440 -1.7 -2.0 cell division protein SepF compare
MMP_RS00895 -1.7 -3.0 hypothetical protein compare
MMP_RS00250 -1.7 -11.1 Flp pilus assembly complex ATPase component TadA compare
MMP_RS01295 -1.7 -9.4 hypothetical protein compare
MMP_RS04585 -1.7 -9.9 AIR synthase related protein compare
MMP_RS00810 -1.7 -6.1 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS08855 -1.7 -6.5 hypothetical protein compare
MMP_RS01310 -1.6 -10.5 hypothetical protein compare
MMP_RS07525 -1.6 -6.5 4Fe-4S binding protein compare
MMP_RS01285 -1.6 -7.8 hypothetical protein compare
MMP_RS08330 -1.6 -4.1 NADH-quinone oxidoreductase subunit H compare
MMP_RS03110 -1.6 -3.7 glycosyltransferase family 2 protein compare
MMP_RS00240 -1.6 -10.6 type II secretion system F family protein compare
MMP_RS07875 -1.6 -3.8 hypothetical protein compare
MMP_RS06885 -1.6 -2.2 50S ribosome-binding GTPase compare
MMP_RS01280 -1.6 -9.1 DUF515 domain-containing protein compare
MMP_RS07600 -1.6 -1.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06110 -1.5 -2.9 ATP-dependent protease LonB compare
MMP_RS01220 -1.5 -6.8 hypothetical protein compare
MMP_RS01305 -1.5 -10.1 hypothetical protein compare
MMP_RS02900 -1.5 -0.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS01315 -1.5 -11.9 DUF2341 domain-containing protein compare
MMP_RS00915 -1.5 -4.3 DUF116 domain-containing protein compare
MMP_RS08370 -1.5 -0.5 cation:proton antiporter subunit C compare
MMP_RS01020 -1.5 -0.9 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS00520 -1.5 -1.5 RNA polymerase Rpb4 family protein compare
MMP_RS00245 -1.5 -11.9 type II secretion system F family protein compare
MMP_RS05555 -1.5 -1.1 DUF4040 domain-containing protein compare
MMP_RS07605 -1.5 -2.7 diadenylate cyclase compare
MMP_RS08195 -1.5 -5.9 hypothetical protein compare
MMP_RS09055 -1.5 -0.8 CAP domain-containing protein compare
MMP_RS04775 -1.5 -2.8 adenosylhomocysteinase compare
MMP_RS00515 -1.5 -0.7 DUF655 domain-containing protein compare
MMP_RS06895 -1.5 -1.2 selenocysteine-specific translation elongation factor compare
MMP_RS06105 -1.5 -5.7 hydrogenase maturation peptidase HycI compare
MMP_RS01955 -1.5 -2.2 hypothetical protein compare
MMP_RS02135 -1.5 -3.5 DUF5612 domain-containing protein compare
MMP_RS03390 -1.5 -4.8 malate dehydrogenase compare
MMP_RS04615 -1.4 -3.4 PDGLE domain-containing protein compare
MMP_RS08820 -1.4 -3.6 hypothetical protein compare
MMP_RS01290 -1.4 -7.4 class III signal peptide-containing protein compare
MMP_RS03095 -1.4 -4.2 diphthine synthase compare
MMP_RS00695 -1.4 -0.8 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06285 -1.4 -1.5 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS04780 -1.4 -2.1 ribonuclease P compare
MMP_RS01915 -1.4 -6.5 DUF354 domain-containing protein compare
MMP_RS08720 -1.4 -1.0 4Fe-4S binding protein compare
MMP_RS03385 -1.4 -0.9 cation diffusion facilitator family transporter compare
MMP_RS05540 -1.4 -2.4 hypothetical protein compare
MMP_RS00720 -1.4 -7.2 metal-dependent hydrolase compare
MMP_RS06130 -1.3 -2.9 peptidylprolyl isomerase compare
MMP_RS07200 -1.3 -4.8 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS01085 -1.3 -1.5 hypothetical protein compare
MMP_RS06980 -1.3 -3.7 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS02010 -1.3 -4.0 PHP domain-containing protein compare
MMP_RS05345 -1.3 -4.8 hypothetical protein compare
MMP_RS06975 -1.3 -1.3 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07730 -1.3 -1.4 pyruvate synthase subunit beta compare
MMP_RS06730 -1.3 -1.2 phosphopantothenate/pantothenate synthetase compare
MMP_RS01975 -1.3 -6.8 hypothetical protein compare
MMP_RS05245 -1.3 -6.1 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS03140 -1.3 -6.3 hypothetical protein compare
MMP_RS06925 -1.3 -1.7 ribonuclease VapC4 compare
MMP_RS07750 -1.3 -4.6 DUF357 domain-containing protein compare
MMP_RS01365 -1.3 -1.5 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS09045 -1.3 -8.0 class III signal peptide-containing protein compare
MMP_RS01895 -1.3 -7.1 flippase compare
MMP_RS06675 -1.3 -5.2 ADP-specific phosphofructokinase compare
MMP_RS04695 -1.2 -4.8 selenide water dikinase SelD compare
MMP_RS08645 -1.2 -3.1 UPF0179 family protein compare
MMP_RS08860 -1.2 -4.4 MinD/ParA family protein compare
MMP_RS01370 -1.2 -6.1 acetate--CoA ligase family protein compare
MMP_RS05250 -1.2 -2.1 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08790 -1.2 -1.3 translation initiation factor IF-2 subunit alpha compare
MMP_RS03035 -1.2 -2.4 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS04955 -1.2 -4.8 DNA topoisomerase I compare
MMP_RS00115 -1.2 -5.9 radical SAM protein compare
MMP_RS04605 -1.2 -2.7 cobalt ECF transporter T component CbiQ compare
MMP_RS03125 -1.2 -3.4 cell division ATPase MinD compare
MMP_RS00305 -1.2 -1.2 phosphoribosyl-ATP diphosphatase compare
MMP_RS05815 -1.2 -1.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08155 -1.2 -4.0 hypothetical protein compare
MMP_RS06865 -1.2 -1.1 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS02190 -1.2 -1.8 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS01600 -1.2 -2.0 50S ribosomal protein L15e compare
MMP_RS08165 -1.1 -1.5 phosphoglycerate dehydrogenase compare
MMP_RS05430 -1.1 -3.6 TIGR00288 family NYN domain-containing protein compare
MMP_RS08785 -1.1 -0.6 RNA-protein complex protein Nop10 compare
MMP_RS02780 -1.1 -6.2 hypothetical protein compare
MMP_RS03145 -1.1 -3.9 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS08000 -1.1 -6.8 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress 8-hydroxy-nitroquinolone across organisms