Experiment set12S319 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS01385		-4.7	-0.4	imidazole glycerol phosphate synthase subunit HisH
MMP_RS00695		-4.4	-0.5	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS00305		-4.1	-1.3	phosphoribosyl-ATP diphosphatase
MMP_RS08300		-3.2	-0.8	metal-sulfur cluster assembly factor
MMP_RS02240		-3.2	-2.0	methanogenesis marker 7 protein
MMP_RS06400		-3.1	-1.0	4Fe-4S binding protein
MMP_RS01265		-3.1	-2.3	hypothetical protein
MMP_RS06730		-2.9	-1.1	phosphopantothenate/pantothenate synthetase
MMP_RS00300		-2.8	-0.5	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS08720		-2.6	-1.0	4Fe-4S binding protein
MMP_RS03435		-2.5	-1.2	ketol-acid reductoisomerase
MMP_RS03025		-2.5	-3.8	molybdenum cofactor guanylyltransferase
MMP_RS06600		-2.4	-0.8	class III signal peptide-containing protein
MMP_RS06020		-2.2	-3.1	archaeoflavoprotein AfpA
MMP_RS07600		-2.2	-1.5	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS06625		-2.2	-1.0	DNA primase
MMP_RS01795		-2.2	-0.8	methanogenesis marker 6 protein
MMP_RS06630		-2.1	-0.5	UPF0058 family protein
MMP_RS03445		-2.1	-0.6	methanogenesis marker 17 protein
MMP_RS06315		-2.1	-0.5	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS07730		-2.1	-1.2	pyruvate synthase subunit beta
MMP_RS03080		-2.1	-2.4	universal stress protein
MMP_RS05815		-2.1	-1.3	NOL1/NOP2/sun family putative RNA methylase
MMP_RS03125		-2.0	-4.2	cell division ATPase MinD
MMP_RS04775		-2.0	-2.0	adenosylhomocysteinase
MMP_RS06340		-2.0	-5.1	phosphoadenosine phosphosulfate reductase family protein
MMP_RS06895		-1.9	-1.0	selenocysteine-specific translation elongation factor
MMP_RS09055		-1.9	-0.6	CAP domain-containing protein
MMP_RS01755		-1.9	-0.7	DUF2097 domain-containing protein
MMP_RS00520		-1.9	-1.0	RNA polymerase Rpb4 family protein
MMP_RS01005		-1.9	-0.5	riboflavin synthase
MMP_RS01830		-1.8	-0.9	tRNA-Val
MMP_RS06575		-1.8	-2.6	fluoride efflux transporter CrcB
MMP_RS08210		-1.8	-1.2	phosphatidylglycerophosphatase A
MMP_RS04720		-1.8	-1.8	DedA family protein
MMP_RS06120		-1.8	-1.1	UPF0147 family protein
MMP_RS03580		-1.8	-2.2	signal recognition particle-docking protein FtsY
MMP_RS00985		-1.8	-3.1	CDC48 family AAA ATPase
MMP_RS07845		-1.8	-1.7	LL-diaminopimelate aminotransferase
MMP_RS05635		-1.8	-6.4	NAD-dependent epimerase/dehydratase family protein
MMP_RS00515		-1.8	-0.6	DUF655 domain-containing protein
MMP_RS06395		-1.8	-2.0	ThiF family adenylyltransferase
MMP_RS01270		-1.7	-11.4	prepilin peptidase
MMP_RS07390		-1.7	-1.3	cell division protein FtsZ
MMP_RS03600		-1.7	-1.3	triose-phosphate isomerase
MMP_RS08855		-1.7	-6.2	hypothetical protein
MMP_RS00240		-1.7	-10.1	type II secretion system F family protein
MMP_RS04015		-1.7	-1.5	hypothetical protein
MMP_RS06285		-1.7	-1.1	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS01310		-1.6	-8.6	hypothetical protein
MMP_RS08790		-1.6	-1.0	translation initiation factor IF-2 subunit alpha
MMP_RS01955		-1.6	-1.5	hypothetical protein
MMP_RS02340		-1.6	-1.2	DNA-directed RNA polymerase subunit E''
MMP_RS01325		-1.6	-0.9	dihydroneopterin aldolase family protein
MMP_RS08745		-1.6	-4.4	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS04780		-1.6	-1.5	ribonuclease P
MMP_RS08860		-1.6	-3.7	MinD/ParA family protein
MMP_RS01285		-1.6	-7.9	hypothetical protein
MMP_RS00245		-1.6	-10.2	type II secretion system F family protein
MMP_RS01305		-1.6	-9.5	hypothetical protein
MMP_RS04900		-1.5	-10.9	hypothetical protein
MMP_RS03400		-1.5	-1.5	archease
MMP_RS00570		-1.5	-1.6	protein-L-isoaspartate O-methyltransferase
MMP_RS01280		-1.5	-9.1	DUF515 domain-containing protein
MMP_RS05245		-1.5	-7.1	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS01960		-1.5	-0.6	hypothetical protein
MMP_RS04585		-1.5	-6.0	AIR synthase related protein
MMP_RS01545		-1.5	-0.6	CBS domain-containing protein
MMP_RS02345		-1.5	-2.1	GTP-dependent dephospho-CoA kinase family protein
MMP_RS01315		-1.5	-11.5	DUF2341 domain-containing protein
MMP_RS08615		-1.5	-1.1	flagellar protein G
MMP_RS04710		-1.5	-1.0	hypothetical protein
MMP_RS08590		-1.5	-2.7	flagellin
MMP_RS03700		-1.5	-4.8	sodium:proton antiporter
MMP_RS00250		-1.4	-9.2	Flp pilus assembly complex ATPase component TadA
MMP_RS06355		-1.4	-1.4	molybdenum cofactor biosynthesis protein MoaE
MMP_RS06035		-1.4	-6.8	glycosyltransferase family 2 protein
MMP_RS06885		-1.4	-1.4	50S ribosome-binding GTPase
MMP_RS08715		-1.4	-0.8	formylmethanofuran dehydrogenase subunit B
MMP_RS02480		-1.4	-1.1	hypothetical protein
MMP_RS00900		-1.4	-1.0	50S ribosomal protein L39e
MMP_RS01600		-1.4	-1.7	50S ribosomal protein L15e
MMP_RS00730		-1.4	-3.3	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS01175		-1.4	-1.8	triphosphoribosyl-dephospho-CoA synthase
MMP_RS01275		-1.4	-3.5	class III signal peptide-containing protein
MMP_RS07755		-1.4	-0.6	DUF555 domain-containing protein
MMP_RS06725		-1.4	-5.8	hypothetical protein
MMP_RS06295		-1.3	-4.7	methanogenesis marker 14 protein
MMP_RS07605		-1.3	-1.7	diadenylate cyclase
MMP_RS07635		-1.3	-4.1	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS01610		-1.3	-1.6	hypothetical protein
MMP_RS01500		-1.3	-1.0	CBS domain-containing protein
MMP_RS05580		-1.3	-8.6	glycosyltransferase
MMP_RS03550		-1.3	-1.0	DUF2124 domain-containing protein
MMP_RS00040		-1.3	-3.7	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS01290		-1.3	-6.0	class III signal peptide-containing protein
MMP_RS07330		-1.3	-9.8	membrane protein
MMP_RS00810		-1.3	-4.0	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS04850		-1.3	-7.6	UPF0254 family protein
MMP_RS02280		-1.3	-0.3	DUF211 domain-containing protein
MMP_RS07420		-1.3	-3.2	metalloregulator ArsR/SmtB family transcription factor
MMP_RS03145		-1.3	-3.2	fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
MMP_RS01800		-1.3	-1.6	TIGR00303 family protein
MMP_RS01700		-1.3	-0.4	dihydroxy-acid dehydratase
MMP_RS08930		-1.2	-0.8	hypothetical protein
MMP_RS05250		-1.2	-1.7	NFYB/HAP3 family transcription factor subunit
MMP_RS07750		-1.2	-3.0	DUF357 domain-containing protein
MMP_RS08675		-1.2	-1.5	class III signal peptide-containing protein
MMP_RS02545		-1.2	-2.9	hypothetical protein
MMP_RS09020		-1.2	-0.8	hypothetical protein
MMP_RS07075		-1.2	-2.3	phosphomannomutase/phosphoglucomutase
MMP_RS07700		-1.2	-4.2	DUF1188 domain-containing protein
MMP_RS01295		-1.2	-5.5	hypothetical protein
MMP_RS02995		-1.2	-2.4	acyl-CoA thioesterase
MMP_RS08370		-1.2	-0.3	cation:proton antiporter subunit C
MMP_RS05845		-1.2	-0.8	tRNA-intron lyase
MMP_RS07355		-1.2	-0.4	transcription factor S
MMP_RS04685		-1.2	-1.3	DUF126 domain-containing protein
MMP_RS00725		-1.2	-3.5	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS08820		-1.2	-2.6	hypothetical protein
MMP_RS00750		-1.2	-1.1	fumarate hydratase
MMP_RS08195		-1.2	-4.3	hypothetical protein
MMP_RS09045		-1.1	-6.2	class III signal peptide-containing protein
MMP_RS02745		-1.1	-1.0	hypothetical protein
MMP_RS04265		-1.1	-1.5	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS02100		-1.1	-1.4	metallophosphoesterase
MMP_RS00110		-1.1	-1.5	hypothetical protein
MMP_RS00325		-1.1	-0.7	RNA-binding protein
MMP_RS08785		-1.1	-0.4	RNA-protein complex protein Nop10
MMP_RS08440		-1.1	-1.2	cell division protein SepF
MMP_RS07200		-1.1	-2.9	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS00770		-1.1	-1.8	hypothetical protein
MMP_RS00915		-1.1	-3.5	DUF116 domain-containing protein
MMP_RS01725		-1.1	-1.9	class I SAM-dependent methyltransferase family protein
MMP_RS02010		-1.1	-2.8	PHP domain-containing protein
MMP_RS06975		-1.1	-0.8	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS00895		-1.1	-1.8	hypothetical protein
MMP_RS01905		-1.1	-6.0	glycosyltransferase
MMP_RS00315		-1.1	-2.0	Nif3-like dinuclear metal center hexameric protein
MMP_RS02410		-1.1	-1.1	ABC transporter substrate-binding protein
MMP_RS04890		-1.1	-0.4	adenylyltransferase/cytidyltransferase family protein
MMP_RS01900		-1.1	-6.2	hypothetical protein
MMP_RS07955		-1.1	-2.4	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS01965		-1.1	-2.0	DUF1616 domain-containing protein
MMP_RS06485		-1.0	-0.4	zinc ribbon domain-containing protein
MMP_RS08830		-1.0	-2.4	GTP-binding protein
MMP_RS07575		-1.0	-1.6	RNA ligase partner protein
MMP_RS03140		-1.0	-3.1	hypothetical protein
MMP_RS03095		-1.0	-3.0	diphthine synthase
MMP_RS01880		-1.0	-3.1	DegT/DnrJ/EryC1/StrS family aminotransferase
MMP_RS05345		-1.0	-3.3	hypothetical protein
MMP_RS05925		-1.0	-1.7	small nuclear ribonucleoprotein
MMP_RS01925		-1.0	-4.0	DUF1616 domain-containing protein
MMP_RS01020		-1.0	-0.4	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS07695		-1.0	-3.0	DUF3236 domain-containing protein
MMP_RS07875		-1.0	-1.8	hypothetical protein
MMP_RS00140		-1.0	-2.4	DUF192 domain-containing protein
MMP_RS03535		-1.0	-1.2	helix-turn-helix transcriptional regulator
MMP_RS01875		-1.0	-4.4	N-acetyltransferase
MMP_RS06435		-1.0	-2.3	CBS domain-containing protein
MMP_RS00125		-1.0	-0.6	DUF2798 domain-containing protein
MMP_RS03640		-1.0	-1.6	archaeal proteasome endopeptidase complex subunit beta
MMP_RS03250		-1.0	-1.3	MJ1244 family protein
MMP_RS01975		-0.9	-6.6	hypothetical protein
MMP_RS05280		-0.9	-2.8	COG1361 S-layer family protein
MMP_RS01885		-0.9	-3.2	Gfo/Idh/MocA family oxidoreductase
MMP_RS05285		-0.9	-3.2	MMPL family transporter
MMP_RS04955		-0.9	-2.7	DNA topoisomerase I
MMP_RS06685		-0.9	-4.3	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS08605		-0.9	-2.1	flagellar protein E
MMP_RS05550		-0.9	-0.3	cation:proton antiporter
MMP_RS07900		-0.9	-1.0	YeeE/YedE family protein
MMP_RS07580		-0.9	-1.0	DUF356 domain-containing protein
MMP_RS01890		-0.9	-1.3	nucleotide sugar dehydrogenase
MMP_RS01195		-0.9	-0.5	metalloregulator ArsR/SmtB family transcription factor
MMP_RS04630		-0.9	-2.2	3'-5' exonuclease
MMP_RS01465		-0.9	-1.1	hypothetical protein
MMP_RS01895		-0.9	-4.0	flippase
MMP_RS06930		-0.8	-4.1	MBL fold metallo-hydrolase
MMP_RS07350		-0.8	-0.8	preprotein translocase subunit Sec61beta
MMP_RS01915		-0.8	-4.6	DUF354 domain-containing protein
MMP_RS03110		-0.8	-2.2	glycosyltransferase family 2 protein
MMP_RS08645		-0.8	-2.4	UPF0179 family protein
MMP_RS06350		-0.8	-1.6	HesA/MoeB/ThiF family protein
MMP_RS02415		-0.8	-0.9	site-specific integrase
MMP_RS01030		-0.8	-1.9	MTAP family purine nucleoside phosphorylase
MMP_RS06475		-0.8	-1.6	FAD-dependent oxidoreductase
MMP_RS07380		-0.8	-0.7	transcription elongation factor Spt5
MMP_RS01365		-0.8	-1.2	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS03385		-0.8	-0.4	cation diffusion facilitator family transporter
MMP_RS03485		-0.8	-1.3	TIGR00267 family protein
MMP_RS01470		-0.8	-1.1	ATP-binding cassette domain-containing protein
MMP_RS00735		-0.8	-1.3	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS09025		-0.8	-0.3	hypothetical protein
MMP_RS02540		-0.8	-2.5	DUF2283 domain-containing protein
MMP_RS02765		-0.8	-1.9	ABC transporter ATP-binding protein
MMP_RS08600		-0.8	-0.8	flagellar protein D
MMP_RS05945		-0.8	-1.0	CBS domain-containing protein
MMP_RS03555		-0.7	-2.5	transcriptional regulator
MMP_RS07190		-0.7	-2.2	chromosome segregation protein SMC

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium Fluorophosphate across organisms