Experiment set12S317 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS05815		-7.5	-1.3	NOL1/NOP2/sun family putative RNA methylase
MMP_RS00520		-7.1	-1.2	RNA polymerase Rpb4 family protein
MMP_RS08940		-6.9	-0.7	MetS family NSS transporter small subunit
MMP_RS09020		-6.7	-1.1	hypothetical protein
MMP_RS06840		-6.4	-0.6	DNA-directed RNA polymerase subunit N
MMP_RS01545		-6.4	-0.6	CBS domain-containing protein
MMP_RS07630		-6.3	-1.1	ATP-binding cassette domain-containing protein
MMP_RS03435		-6.3	-1.2	ketol-acid reductoisomerase
MMP_RS03445		-6.0	-0.6	methanogenesis marker 17 protein
MMP_RS08350		-6.0	-0.6	hypothetical protein
MMP_RS06485		-5.9	-0.6	zinc ribbon domain-containing protein
MMP_RS08785		-5.8	-0.6	RNA-protein complex protein Nop10
MMP_RS05835		-5.5	-0.6	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS07730		-5.5	-1.2	pyruvate synthase subunit beta
MMP_RS02605		-5.5	-0.5	MotA/TolQ/ExbB proton channel family protein
MMP_RS05550		-5.2	-0.5	cation:proton antiporter
MMP_RS01755		-5.2	-0.7	DUF2097 domain-containing protein
MMP_RS08720		-5.2	-1.0	4Fe-4S binding protein
MMP_RS00305		-5.1	-1.1	phosphoribosyl-ATP diphosphatase
MMP_RS03475		-4.9	-0.5	hypothetical protein
MMP_RS01960		-4.8	-0.7	hypothetical protein
MMP_RS07005		-4.6	-0.5	4Fe-4S binding protein
MMP_RS07860		-4.6	-0.5	hypothetical protein
MMP_RS05920		-4.6	-0.5	50S ribosomal protein L37e
MMP_RS07545		-4.5	-0.6	HTH domain-containing protein
MMP_RS00695		-4.2	-0.6	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS06395		-4.2	-2.0	ThiF family adenylyltransferase
MMP_RS06630		-4.1	-0.6	UPF0058 family protein
MMP_RS04890		-3.8	-0.5	adenylyltransferase/cytidyltransferase family protein
MMP_RS01225		-3.4	-2.8	DUF5379 domain-containing protein
MMP_RS07075		-3.3	-2.7	phosphomannomutase/phosphoglucomutase
MMP_RS04685		-3.0	-1.9	DUF126 domain-containing protein
MMP_RS01265		-2.9	-2.0	hypothetical protein
MMP_RS06525		-2.8	-0.8	YciI family protein
MMP_RS08790		-2.7	-1.2	translation initiation factor IF-2 subunit alpha
MMP_RS06020		-2.5	-2.2	archaeoflavoprotein AfpA
MMP_RS00110		-2.5	-1.4	hypothetical protein
MMP_RS08315		-2.5	-2.0	S-methyl-5-thioribose-1-phosphate isomerase
MMP_RS03580		-2.5	-2.0	signal recognition particle-docking protein FtsY
MMP_RS06725		-2.5	-5.1	hypothetical protein
MMP_RS01610		-2.4	-1.6	hypothetical protein
MMP_RS00985		-2.3	-2.8	CDC48 family AAA ATPase
MMP_RS01380		-2.3	-2.0	PHP domain-containing protein
MMP_RS01720		-2.3	-1.3	replication factor C large subunit
MMP_RS07845		-2.2	-1.6	LL-diaminopimelate aminotransferase
MMP_RS08745		-2.1	-3.2	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS06670		-2.1	-2.8	glucose-6-phosphate isomerase
MMP_RS02800		-2.1	-4.0	nucleotidyltransferase domain-containing protein
MMP_RS07755		-2.1	-0.7	DUF555 domain-containing protein
MMP_RS05965		-2.0	-1.9	carboxymuconolactone decarboxylase family protein
MMP_RS01880		-2.0	-2.7	DegT/DnrJ/EryC1/StrS family aminotransferase
MMP_RS07605		-2.0	-1.5	diadenylate cyclase
MMP_RS03960		-2.0	-0.7	hypothetical protein
MMP_RS03600		-2.0	-1.1	triose-phosphate isomerase
MMP_RS00810		-2.0	-2.1	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS01800		-1.9	-1.7	TIGR00303 family protein
MMP_RS00895		-1.9	-1.8	hypothetical protein
MMP_RS07635		-1.9	-3.5	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS05925		-1.9	-1.1	small nuclear ribonucleoprotein
MMP_RS01900		-1.9	-6.0	hypothetical protein
MMP_RS01645		-1.9	-2.1	SWIM zinc finger family protein
MMP_RS02020		-1.9	-1.6	gamma-glutamylcyclotransferase
MMP_RS00735		-1.9	-1.9	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS06900		-1.8	-1.0	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS05295		-1.8	-4.2	minichromosome maintenance protein MCM
MMP_RS04090		-1.7	-1.2	hypothetical protein
MMP_RS04710		-1.7	-0.8	hypothetical protein
MMP_RS07820		-1.7	-1.6	UPF0104 family protein
MMP_RS02195		-1.7	-1.7	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS00325		-1.7	-0.7	RNA-binding protein
MMP_RS01665		-1.7	-1.3	DUF2111 domain-containing protein
MMP_RS00130		-1.6	-0.6	nickel-responsive transcriptional regulator NikR
MMP_RS04585		-1.6	-3.8	AIR synthase related protein
MMP_RS06110		-1.6	-1.8	ATP-dependent protease LonB
MMP_RS04790		-1.6	-4.8	4-hydroxy-tetrahydrodipicolinate reductase
MMP_RS03035		-1.6	-1.4	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS06940		-1.6	-1.8	polyprenyl diphosphate synthase
MMP_RS08330		-1.6	-2.2	NADH-quinone oxidoreductase subunit H
MMP_RS04055		-1.5	-0.9	hypothetical protein
MMP_RS01990		-1.5	-1.8	hypothetical protein
MMP_RS08370		-1.5	-0.3	cation:proton antiporter subunit C
MMP_RS04480		-1.5	-5.5	lysine 2 3-aminomutase
MMP_RS08460		-1.5	-1.0	proteasome-activating nucleotidase
MMP_RS08675		-1.5	-1.8	class III signal peptide-containing protein
MMP_RS06350		-1.5	-3.5	HesA/MoeB/ThiF family protein
MMP_RS03450		-1.5	-0.9	glycine synthesis protein GlyXS (from data)
MMP_RS03700		-1.5	-2.5	sodium:proton antiporter
MMP_RS08165		-1.5	-1.3	phosphoglycerate dehydrogenase
MMP_RS04485		-1.5	-4.1	putative beta-lysine N-acetyltransferase
MMP_RS02145		-1.4	-2.8	winged helix-turn-helix transcriptional regulator
MMP_RS04720		-1.4	-0.9	DedA family protein
MMP_RS01890		-1.4	-1.6	nucleotide sugar dehydrogenase
MMP_RS03025		-1.4	-1.9	molybdenum cofactor guanylyltransferase
MMP_RS06315		-1.4	-0.4	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS05250		-1.4	-1.4	NFYB/HAP3 family transcription factor subunit
MMP_RS00040		-1.4	-1.9	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS01840		-1.4	-2.6	TIGR00289 family protein
MMP_RS07345		-1.4	-2.0	glycine synthesis protein GlyXL (from data)
MMP_RS05425		-1.4	-1.8	monovalent cation/H+ antiporter complex subunit F
MMP_RS08210		-1.3	-0.9	phosphatidylglycerophosphatase A
MMP_RS06610		-1.3	-2.0	DUF2334 domain-containing protein
MMP_RS01925		-1.3	-2.9	DUF1616 domain-containing protein
MMP_RS07875		-1.3	-1.4	hypothetical protein
MMP_RS01500		-1.3	-0.7	CBS domain-containing protein
MMP_RS04900		-1.3	-7.9	hypothetical protein
MMP_RS01875		-1.3	-3.2	N-acetyltransferase
MMP_RS06625		-1.3	-0.6	DNA primase
MMP_RS06435		-1.3	-1.9	CBS domain-containing protein
MMP_RS01905		-1.3	-4.4	glycosyltransferase
MMP_RS00720		-1.3	-3.1	metal-dependent hydrolase
MMP_RS00880		-1.2	-1.8	ribosome assembly RNA-binding protein YhbY
MMP_RS07580		-1.2	-1.1	DUF356 domain-containing protein
MMP_RS08435		-1.2	-0.9	Era-like GTP-binding protein
MMP_RS07380		-1.2	-0.9	transcription elongation factor Spt5
MMP_RS04690		-1.2	-1.5	class III signal peptide-containing protein
MMP_RS01275		-1.2	-2.2	class III signal peptide-containing protein
MMP_RS06585		-1.2	-0.7	DMT family protein
MMP_RS05540		-1.2	-1.5	hypothetical protein
MMP_RS06120		-1.2	-0.6	UPF0147 family protein
MMP_RS04410		-1.2	-1.6	hypothetical protein
MMP_RS05560		-1.2	-3.0	deoxyuridine 5'-triphosphate nucleotidohydrolase
MMP_RS06895		-1.2	-0.6	selenocysteine-specific translation elongation factor
MMP_RS01885		-1.2	-2.2	Gfo/Idh/MocA family oxidoreductase
MMP_RS02545		-1.2	-2.4	hypothetical protein
MMP_RS01725		-1.2	-1.3	class I SAM-dependent methyltransferase family protein
MMP_RS04630		-1.2	-2.7	3'-5' exonuclease
MMP_RS04615		-1.2	-1.2	PDGLE domain-containing protein
MMP_RS03640		-1.2	-1.4	archaeal proteasome endopeptidase complex subunit beta
MMP_RS00240		-1.2	-3.8	type II secretion system F family protein
MMP_RS08995		-1.1	-0.6	hypothetical protein
MMP_RS02135		-1.1	-1.4	DUF5612 domain-containing protein
MMP_RS00115		-1.1	-3.7	radical SAM protein
MMP_RS05875		-1.1	-2.0	hydroxyethylthiazole kinase
MMP_RS02235		-1.1	-2.8	CBS domain-containing protein
MMP_RS06885		-1.1	-0.9	50S ribosome-binding GTPase
MMP_RS05265		-1.1	-0.8	2-isopropylmalate synthase
MMP_RS06215		-1.1	-1.0	30S ribosomal protein S6e
MMP_RS03485		-1.1	-1.5	TIGR00267 family protein
MMP_RS08820		-1.1	-1.5	hypothetical protein
MMP_RS07695		-1.1	-2.3	DUF3236 domain-containing protein
MMP_RS01910		-1.1	-2.6	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)
MMP_RS06975		-1.1	-0.5	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS00730		-1.1	-1.5	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS02940		-1.1	-2.1	TatD family hydrolase
MMP_RS05850		-1.1	-1.5	Ldh family oxidoreductase
MMP_RS07445		-1.1	-3.0	helix-turn-helix domain-containing protein
MMP_RS07575		-1.1	-1.7	RNA ligase partner protein
MMP_RS03020		-1.1	-2.0	peptidylprolyl isomerase
MMP_RS04785		-1.1	-4.3	hypothetical protein
MMP_RS05635		-1.1	-3.7	NAD-dependent epimerase/dehydratase family protein
MMP_RS08155		-1.1	-2.4	hypothetical protein
MMP_RS08915		-1.1	-1.3	2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
MMP_RS05580		-1.0	-5.0	glycosyltransferase
MMP_RS04250		-1.0	-2.5	PC4/YdbC family ssDNA-binding protein
MMP_RS04775		-1.0	-0.9	adenosylhomocysteinase
MMP_RS05245		-1.0	-2.7	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS00250		-1.0	-5.3	Flp pilus assembly complex ATPase component TadA
MMP_RS03100		-1.0	-1.9	hypothetical protein
MMP_RS01020		-1.0	-0.4	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS01285		-1.0	-3.2	hypothetical protein
MMP_RS04780		-1.0	-0.7	ribonuclease P
MMP_RS07900		-1.0	-1.0	YeeE/YedE family protein
MMP_RS01660		-1.0	-0.7	hypothetical protein
MMP_RS03125		-1.0	-1.4	cell division ATPase MinD
MMP_RS06930		-1.0	-3.0	MBL fold metallo-hydrolase
MMP_RS03090		-1.0	-3.0	cation:proton antiporter
MMP_RS04955		-0.9	-1.8	DNA topoisomerase I
MMP_RS02835		-0.9	-1.4	CGGC domain-containing protein
MMP_RS00915		-0.9	-1.8	DUF116 domain-containing protein
MMP_RS00725		-0.9	-2.2	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS02240		-0.9	-0.7	methanogenesis marker 7 protein
MMP_RS07330		-0.9	-4.9	membrane protein
MMP_RS07955		-0.9	-1.4	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS08645		-0.9	-2.1	UPF0179 family protein
MMP_RS01325		-0.9	-0.4	dihydroneopterin aldolase family protein
MMP_RS00310		-0.9	-3.0	CBS domain-containing protein
MMP_RS06365		-0.9	-0.5	hypothetical protein
MMP_RS07115		-0.9	-2.2	MBL fold metallo-hydrolase
MMP_RS06475		-0.9	-1.0	FAD-dependent oxidoreductase
MMP_RS01365		-0.8	-0.8	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS05535		-0.8	-1.4	hypothetical protein
MMP_RS08340		-0.8	-1.2	4Fe-4S binding protein
MMP_RS02415		-0.8	-0.5	site-specific integrase
MMP_RS01310		-0.8	-3.5	hypothetical protein
MMP_RS08855		-0.8	-2.5	hypothetical protein
MMP_RS01220		-0.8	-1.7	hypothetical protein
MMP_RS05460		-0.8	-2.1	YcaO-related McrA-glycine thioamidation protein
MMP_RS03245		-0.8	-1.7	DNA repair and recombination protein RadB
MMP_RS07735		-0.8	-0.3	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS02610		-0.8	-1.5	DUF2162 domain-containing protein
MMP_RS08195		-0.8	-2.3	hypothetical protein
MMP_RS02245		-0.8	-0.7	hypothetical protein
MMP_RS07420		-0.8	-1.4	metalloregulator ArsR/SmtB family transcription factor
MMP_RS08650		-0.8	-0.7	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS06290		-0.8	-1.0	DNA repair and recombination protein RadA
MMP_RS08395		-0.8	-1.8	DsrE family protein
MMP_RS01290		-0.8	-2.8	class III signal peptide-containing protein
MMP_RS02870		-0.8	-2.2	hypothetical protein
MMP_RS06705		-0.8	-2.1	formate/nitrite transporter family protein
MMP_RS02540		-0.8	-1.8	DUF2283 domain-containing protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium Chloride across organisms