Experiment set12S315 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete Spiramycin 0.1 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS08210 -7.2 -1.3 phosphatidylglycerophosphatase A compare
MMP_RS03435 -6.3 -1.1 ketol-acid reductoisomerase compare
MMP_RS08300 -5.3 -0.8 metal-sulfur cluster assembly factor compare
MMP_RS08720 -5.1 -0.9 4Fe-4S binding protein compare
MMP_RS03475 -5.0 -0.4 hypothetical protein compare
MMP_RS05920 -4.6 -0.4 50S ribosomal protein L37e compare
MMP_RS07545 -4.5 -0.5 HTH domain-containing protein compare
MMP_RS06895 -4.4 -1.1 selenocysteine-specific translation elongation factor compare
MMP_RS05835 -4.3 -0.5 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS08650 -4.1 -2.5 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS00130 -4.1 -0.6 nickel-responsive transcriptional regulator NikR compare
MMP_RS06400 -4.0 -1.0 4Fe-4S binding protein compare
MMP_RS01325 -3.7 -1.2 dihydroneopterin aldolase family protein compare
MMP_RS04710 -3.6 -1.3 hypothetical protein compare
MMP_RS07390 -3.6 -1.9 cell division protein FtsZ compare
MMP_RS07735 -3.5 -0.4 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS01020 -3.5 -0.7 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS07630 -3.4 -1.1 ATP-binding cassette domain-containing protein compare
MMP_RS06350 -3.3 -4.3 HesA/MoeB/ThiF family protein compare
MMP_RS01960 -3.3 -0.7 hypothetical protein compare
MMP_RS07635 -3.3 -6.7 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07625 -3.1 -2.1 cobalt ECF transporter T component CbiQ compare
MMP_RS03445 -3.0 -0.6 methanogenesis marker 17 protein compare
MMP_RS09020 -3.0 -1.1 hypothetical protein compare
MMP_RS00110 -3.0 -2.2 hypothetical protein compare
MMP_RS03035 -2.9 -2.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS03385 -2.8 -0.7 cation diffusion facilitator family transporter compare
MMP_RS02240 -2.7 -1.9 methanogenesis marker 7 protein compare
MMP_RS02145 -2.7 -6.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS01175 -2.6 -2.2 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS04890 -2.6 -0.5 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01890 -2.5 -3.0 nucleotide sugar dehydrogenase compare
MMP_RS06840 -2.5 -0.7 DNA-directed RNA polymerase subunit N compare
MMP_RS03600 -2.5 -1.5 triose-phosphate isomerase compare
MMP_RS01755 -2.5 -0.7 DUF2097 domain-containing protein compare
MMP_RS03080 -2.4 -2.2 universal stress protein compare
MMP_RS06215 -2.4 -1.7 30S ribosomal protein S6e compare
MMP_RS01545 -2.4 -0.7 CBS domain-containing protein compare
MMP_RS03205 -2.3 -0.8 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS07845 -2.3 -1.4 LL-diaminopimelate aminotransferase compare
MMP_RS00300 -2.2 -0.4 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS01500 -2.2 -1.3 CBS domain-containing protein compare
MMP_RS00985 -2.2 -3.3 CDC48 family AAA ATPase compare
MMP_RS06355 -2.1 -1.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01880 -2.1 -4.8 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS04900 -2.0 -14.4 hypothetical protein compare
MMP_RS06285 -2.0 -1.1 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS01795 -2.0 -0.7 methanogenesis marker 6 protein compare
MMP_RS03125 -2.0 -3.7 cell division ATPase MinD compare
MMP_RS07695 -2.0 -4.8 DUF3236 domain-containing protein compare
MMP_RS01385 -2.0 -0.3 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01265 -1.9 -2.0 hypothetical protein compare
MMP_RS01100 -1.9 -0.8 ABC transporter ATP-binding protein compare
MMP_RS03580 -1.9 -1.8 signal recognition particle-docking protein FtsY compare
MMP_RS02340 -1.9 -1.0 DNA-directed RNA polymerase subunit E'' compare
MMP_RS07755 -1.9 -0.7 DUF555 domain-containing protein compare
MMP_RS08435 -1.9 -1.3 Era-like GTP-binding protein compare
MMP_RS02800 -1.8 -4.4 nucleotidyltransferase domain-containing protein compare
MMP_RS00040 -1.8 -3.3 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS06130 -1.8 -1.8 peptidylprolyl isomerase compare
MMP_RS07075 -1.8 -2.8 phosphomannomutase/phosphoglucomutase compare
MMP_RS02875 -1.8 -5.9 chorismate pyruvate-lyase family protein compare
MMP_RS03640 -1.8 -2.5 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01270 -1.8 -8.8 prepilin peptidase compare
MMP_RS03015 -1.8 -6.0 GTP 3' 8-cyclase MoaA compare
MMP_RS06230 -1.8 -1.4 helix-turn-helix domain-containing protein compare
MMP_RS03320 -1.8 -2.2 metal-dependent transcriptional regulator compare
MMP_RS06730 -1.8 -0.9 phosphopantothenate/pantothenate synthetase compare
MMP_RS04585 -1.8 -6.6 AIR synthase related protein compare
MMP_RS07380 -1.8 -1.1 transcription elongation factor Spt5 compare
MMP_RS06855 -1.7 -5.1 hypothetical protein compare
MMP_RS01700 -1.7 -0.5 dihydroxy-acid dehydratase compare
MMP_RS06340 -1.7 -3.9 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06295 -1.7 -2.8 methanogenesis marker 14 protein compare
MMP_RS06020 -1.7 -2.7 archaeoflavoprotein AfpA compare
MMP_RS00695 -1.7 -0.5 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01925 -1.7 -5.9 DUF1616 domain-containing protein compare
MMP_RS08855 -1.7 -6.1 hypothetical protein compare
MMP_RS04850 -1.7 -8.6 UPF0254 family protein compare
MMP_RS07200 -1.6 -3.4 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS05635 -1.6 -5.8 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS07385 -1.6 -1.2 protein translocase SEC61 complex subunit gamma compare
MMP_RS03395 -1.6 -2.4 hypothetical protein compare
MMP_RS01225 -1.6 -2.2 DUF5379 domain-containing protein compare
MMP_RS03110 -1.6 -3.8 glycosyltransferase family 2 protein compare
MMP_RS08675 -1.6 -1.4 class III signal peptide-containing protein compare
MMP_RS08860 -1.6 -3.7 MinD/ParA family protein compare
MMP_RS05540 -1.6 -2.1 hypothetical protein compare
MMP_RS06120 -1.6 -0.9 UPF0147 family protein compare
MMP_RS05815 -1.6 -1.2 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS03960 -1.6 -0.7 hypothetical protein compare
MMP_RS05845 -1.6 -0.8 tRNA-intron lyase compare
MMP_RS01310 -1.5 -9.1 hypothetical protein compare
MMP_RS03700 -1.5 -4.5 sodium:proton antiporter compare
MMP_RS04485 -1.5 -5.9 putative beta-lysine N-acetyltransferase compare
MMP_RS08820 -1.5 -2.4 hypothetical protein compare
MMP_RS02345 -1.5 -1.9 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS08370 -1.5 -0.3 cation:proton antiporter subunit C compare
MMP_RS08645 -1.5 -3.8 UPF0179 family protein compare
MMP_RS02175 -1.5 -0.4 DUF1611 domain-containing protein compare
MMP_RS05515 -1.5 -3.8 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS05295 -1.5 -4.8 minichromosome maintenance protein MCM compare
MMP_RS03140 -1.5 -6.0 hypothetical protein compare
MMP_RS01290 -1.5 -6.5 class III signal peptide-containing protein compare
MMP_RS02610 -1.5 -2.6 DUF2162 domain-containing protein compare
MMP_RS01900 -1.5 -6.3 hypothetical protein compare
MMP_RS06900 -1.5 -1.2 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS00250 -1.5 -7.8 Flp pilus assembly complex ATPase component TadA compare
MMP_RS01285 -1.4 -5.3 hypothetical protein compare
MMP_RS00245 -1.4 -10.1 type II secretion system F family protein compare
MMP_RS07580 -1.4 -1.2 DUF356 domain-containing protein compare
MMP_RS03400 -1.4 -1.3 archease compare
MMP_RS01280 -1.4 -7.6 DUF515 domain-containing protein compare
MMP_RS08535 -1.4 -4.3 bis-aminopropyl spermidine synthase family protein conserved
MMP_RS07330 -1.4 -9.0 membrane protein compare
MMP_RS01875 -1.4 -4.4 N-acetyltransferase compare
MMP_RS07540 -1.4 -2.2 CBS domain-containing protein compare
MMP_RS07525 -1.4 -3.1 4Fe-4S binding protein compare
MMP_RS01335 -1.4 -0.9 prefoldin subunit beta compare
MMP_RS06980 -1.4 -3.6 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS09045 -1.4 -6.8 class III signal peptide-containing protein compare
MMP_RS01005 -1.4 -0.6 riboflavin synthase compare
MMP_RS00315 -1.3 -2.3 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS00240 -1.3 -6.6 type II secretion system F family protein compare
MMP_RS06925 -1.3 -1.0 ribonuclease VapC4 compare
MMP_RS05580 -1.3 -8.1 glycosyltransferase compare
MMP_RS03145 -1.3 -2.9 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS00520 -1.3 -0.8 RNA polymerase Rpb4 family protein compare
MMP_RS01305 -1.3 -8.4 hypothetical protein compare
MMP_RS06035 -1.3 -4.5 glycosyltransferase family 2 protein compare
MMP_RS01295 -1.3 -5.5 hypothetical protein compare
MMP_RS07750 -1.3 -2.4 DUF357 domain-containing protein compare
MMP_RS06975 -1.3 -0.8 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS07700 -1.3 -4.8 DUF1188 domain-containing protein compare
MMP_RS06625 -1.3 -0.8 DNA primase compare
MMP_RS03390 -1.3 -3.4 malate dehydrogenase compare
MMP_RS08195 -1.3 -4.7 hypothetical protein compare
MMP_RS07710 -1.3 -4.0 cell division protein FtsZ compare
MMP_RS06725 -1.3 -3.9 hypothetical protein compare
MMP_RS02930 -1.3 -1.5 class I SAM-dependent methyltransferase compare
MMP_RS05245 -1.3 -4.5 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS03250 -1.3 -1.4 MJ1244 family protein compare
MMP_RS02410 -1.3 -1.3 ABC transporter substrate-binding protein compare
MMP_RS07875 -1.2 -2.6 hypothetical protein compare
MMP_RS07730 -1.2 -1.0 pyruvate synthase subunit beta compare
MMP_RS00810 -1.2 -3.4 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS05280 -1.2 -5.6 COG1361 S-layer family protein compare
MMP_RS08615 -1.2 -1.0 flagellar protein G compare
MMP_RS05265 -1.2 -1.1 2-isopropylmalate synthase compare
MMP_RS01315 -1.2 -8.8 DUF2341 domain-containing protein compare
MMP_RS04480 -1.2 -7.0 lysine 2 3-aminomutase compare
MMP_RS01800 -1.2 -1.6 TIGR00303 family protein compare
MMP_RS08790 -1.2 -0.8 translation initiation factor IF-2 subunit alpha compare
MMP_RS05285 -1.2 -3.6 MMPL family transporter compare
MMP_RS01885 -1.2 -3.4 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS04780 -1.2 -1.2 ribonuclease P compare
MMP_RS01610 -1.2 -1.5 hypothetical protein compare
MMP_RS08440 -1.2 -1.3 cell division protein SepF compare
MMP_RS02935 -1.2 -1.7 A24 family peptidase compare
MMP_RS05345 -1.2 -3.1 hypothetical protein compare
MMP_RS02235 -1.1 -4.4 CBS domain-containing protein compare
MMP_RS03095 -1.1 -2.8 diphthine synthase compare
MMP_RS01600 -1.1 -1.2 50S ribosomal protein L15e compare
MMP_RS02190 -1.1 -1.3 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS05695 -1.1 -3.6 phospholipase D-like domain-containing protein compare
MMP_RS00125 -1.1 -0.6 DUF2798 domain-containing protein compare
MMP_RS07600 -1.1 -1.0 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS01910 -1.1 -4.0 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS00915 -1.1 -2.9 DUF116 domain-containing protein compare
MMP_RS01220 -1.1 -2.1 hypothetical protein compare
MMP_RS07115 -1.1 -3.1 MBL fold metallo-hydrolase compare
MMP_RS06475 -1.1 -1.7 FAD-dependent oxidoreductase compare
MMP_RS03025 -1.1 -2.3 molybdenum cofactor guanylyltransferase compare
MMP_RS07605 -1.1 -1.3 diadenylate cyclase compare
MMP_RS00305 -1.1 -0.6 phosphoribosyl-ATP diphosphatase compare
MMP_RS00725 -1.1 -2.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS06530 -1.1 -2.7 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS05850 -1.1 -1.1 Ldh family oxidoreductase compare
MMP_RS01525 -1.0 -0.7 nucleoside-diphosphate kinase compare
MMP_RS02195 -1.0 -1.2 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS04035 -1.0 -1.2 hypothetical protein compare
MMP_RS00850 -1.0 -2.2 TIGR01177 family methyltransferase compare
MMP_RS01955 -1.0 -1.1 hypothetical protein compare
MMP_RS08715 -1.0 -0.6 formylmethanofuran dehydrogenase subunit B compare
MMP_RS00060 -1.0 -0.8 3-dehydroquinate synthase II compare
MMP_RS05255 -1.0 -3.9 CBS domain-containing protein compare
MMP_RS06885 -1.0 -1.0 50S ribosome-binding GTPase compare
MMP_RS08745 -1.0 -2.8 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS01745 -1.0 -2.3 AMP phosphorylase compare
MMP_RS00730 -1.0 -2.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS00310 -1.0 -4.2 CBS domain-containing protein compare
MMP_RS06395 -1.0 -1.4 ThiF family adenylyltransferase compare
MMP_RS08445 -1.0 -1.4 DUF2099 family protein compare
MMP_RS04790 -1.0 -4.0 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS03485 -1.0 -1.6 TIGR00267 family protein compare
MMP_RS01905 -1.0 -4.3 glycosyltransferase compare
MMP_RS07350 -1.0 -0.5 preprotein translocase subunit Sec61beta compare
MMP_RS07355 -1.0 -0.4 transcription factor S compare
MMP_RS08240 -1.0 -1.8 methanogenesis marker 16 metalloprotein compare
MMP_RS01540 -1.0 -1.0 DUF504 domain-containing protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress Spiramycin in Methanococcus maripaludis S2

For stress Spiramycin across organisms