Experiment set12S310 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS05550		-5.4	-0.5	cation:proton antiporter
MMP_RS08720		-5.3	-1.0	4Fe-4S binding protein
MMP_RS06895		-5.3	-1.2	selenocysteine-specific translation elongation factor
MMP_RS01960		-5.0	-0.7	hypothetical protein
MMP_RS02900		-4.8	-0.4	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS06730		-4.7	-1.2	phosphopantothenate/pantothenate synthetase
MMP_RS05920		-4.7	-0.4	50S ribosomal protein L37e
MMP_RS01385		-4.7	-0.4	imidazole glycerol phosphate synthase subunit HisH
MMP_RS00520		-4.1	-1.2	RNA polymerase Rpb4 family protein
MMP_RS08715		-4.0	-1.2	formylmethanofuran dehydrogenase subunit B
MMP_RS06355		-3.9	-1.6	molybdenum cofactor biosynthesis protein MoaE
MMP_RS03400		-3.7	-1.9	archease
MMP_RS08435		-3.2	-1.5	Era-like GTP-binding protein
MMP_RS02175		-3.1	-0.5	DUF1611 domain-containing protein
MMP_RS03960		-3.1	-0.8	hypothetical protein
MMP_RS02800		-2.9	-5.4	nucleotidyltransferase domain-containing protein
MMP_RS00750		-2.9	-1.8	fumarate hydratase
MMP_RS07730		-2.9	-1.6	pyruvate synthase subunit beta
MMP_RS01175		-2.9	-2.7	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06230		-2.8	-2.1	helix-turn-helix domain-containing protein
MMP_RS05845		-2.8	-1.2	tRNA-intron lyase
MMP_RS07075		-2.7	-3.1	phosphomannomutase/phosphoglucomutase
MMP_RS07630		-2.7	-1.1	ATP-binding cassette domain-containing protein
MMP_RS07390		-2.6	-1.5	cell division protein FtsZ
MMP_RS01380		-2.6	-3.1	PHP domain-containing protein
MMP_RS00915		-2.6	-4.4	DUF116 domain-containing protein
MMP_RS00305		-2.6	-1.2	phosphoribosyl-ATP diphosphatase
MMP_RS06625		-2.5	-1.0	DNA primase
MMP_RS00985		-2.5	-4.1	CDC48 family AAA ATPase
MMP_RS06350		-2.5	-4.2	HesA/MoeB/ThiF family protein
MMP_RS02145		-2.5	-6.1	winged helix-turn-helix transcriptional regulator
MMP_RS08860		-2.5	-4.0	MinD/ParA family protein
MMP_RS06315		-2.5	-0.5	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS02195		-2.4	-1.9	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS06295		-2.4	-4.4	methanogenesis marker 14 protein
MMP_RS01265		-2.4	-2.3	hypothetical protein
MMP_RS04900		-2.4	-16.1	hypothetical protein
MMP_RS06290		-2.4	-3.1	DNA repair and recombination protein RadA
MMP_RS03015		-2.3	-5.5	GTP 3' 8-cyclase MoaA
MMP_RS01270		-2.3	-12.1	prepilin peptidase
MMP_RS06020		-2.3	-2.8	archaeoflavoprotein AfpA
MMP_RS00240		-2.3	-11.9	type II secretion system F family protein
MMP_RS05295		-2.3	-5.9	minichromosome maintenance protein MCM
MMP_RS01295		-2.3	-9.8	hypothetical protein
MMP_RS00245		-2.3	-14.1	type II secretion system F family protein
MMP_RS07600		-2.3	-1.3	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS01280		-2.2	-11.5	DUF515 domain-containing protein
MMP_RS08210		-2.2	-1.2	phosphatidylglycerophosphatase A
MMP_RS06395		-2.2	-2.0	ThiF family adenylyltransferase
MMP_RS03475		-2.2	-0.4	hypothetical protein
MMP_RS01305		-2.2	-13.1	hypothetical protein
MMP_RS01290		-2.2	-10.3	class III signal peptide-containing protein
MMP_RS08675		-2.1	-1.9	class III signal peptide-containing protein
MMP_RS00250		-2.1	-13.6	Flp pilus assembly complex ATPase component TadA
MMP_RS05515		-2.1	-4.4	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS00675		-2.1	-0.5	nitroreductase family protein
MMP_RS03640		-2.1	-2.0	archaeal proteasome endopeptidase complex subunit beta
MMP_RS08635		-2.1	-1.1	UbiA family prenyltransferase
MMP_RS01310		-2.1	-11.6	hypothetical protein
MMP_RS07005		-2.1	-0.4	4Fe-4S binding protein
MMP_RS01880		-2.1	-4.7	DegT/DnrJ/EryC1/StrS family aminotransferase
MMP_RS01285		-2.0	-7.3	hypothetical protein
MMP_RS01005		-2.0	-0.8	riboflavin synthase
MMP_RS06365		-2.0	-1.3	hypothetical protein
MMP_RS06035		-2.0	-6.3	glycosyltransferase family 2 protein
MMP_RS05635		-2.0	-6.3	NAD-dependent epimerase/dehydratase family protein
MMP_RS02355		-2.0	-1.7	30S ribosomal protein S27ae
MMP_RS07755		-2.0	-0.7	DUF555 domain-containing protein
MMP_RS07845		-2.0	-1.9	LL-diaminopimelate aminotransferase
MMP_RS00730		-2.0	-3.3	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS00810		-1.9	-3.6	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS01830		-1.9	-1.0	tRNA-Val
MMP_RS01900		-1.9	-9.2	hypothetical protein
MMP_RS01220		-1.9	-3.8	hypothetical protein
MMP_RS01315		-1.9	-13.6	DUF2341 domain-containing protein
MMP_RS07710		-1.9	-4.5	cell division protein FtsZ
MMP_RS08820		-1.9	-2.7	hypothetical protein
MMP_RS06400		-1.9	-0.7	4Fe-4S binding protein
MMP_RS09020		-1.9	-0.8	hypothetical protein
MMP_RS03245		-1.9	-2.6	DNA repair and recombination protein RadB
MMP_RS01725		-1.9	-2.6	class I SAM-dependent methyltransferase family protein
MMP_RS07605		-1.9	-1.9	diadenylate cyclase
MMP_RS01610		-1.9	-1.7	hypothetical protein
MMP_RS09045		-1.9	-9.6	class III signal peptide-containing protein
MMP_RS04685		-1.8	-1.3	DUF126 domain-containing protein
MMP_RS07635		-1.8	-4.7	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS07330		-1.8	-11.6	membrane protein
MMP_RS06865		-1.8	-1.6	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS01875		-1.8	-4.9	N-acetyltransferase
MMP_RS05850		-1.8	-2.3	Ldh family oxidoreductase
MMP_RS08785		-1.8	-0.5	RNA-protein complex protein Nop10
MMP_RS07725		-1.8	-2.2	4Fe-4S dicluster domain-containing protein
MMP_RS05580		-1.8	-8.5	glycosyltransferase
MMP_RS08855		-1.8	-7.0	hypothetical protein
MMP_RS05355		-1.8	-0.5	hypothetical protein
MMP_RS03600		-1.8	-1.3	triose-phosphate isomerase
MMP_RS07695		-1.8	-3.8	DUF3236 domain-containing protein
MMP_RS06600		-1.8	-0.8	class III signal peptide-containing protein
MMP_RS06285		-1.7	-1.1	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS01225		-1.7	-2.2	DUF5379 domain-containing protein
MMP_RS08195		-1.7	-6.5	hypothetical protein
MMP_RS06925		-1.7	-1.4	ribonuclease VapC4
MMP_RS04585		-1.7	-5.9	AIR synthase related protein
MMP_RS04890		-1.7	-0.5	adenylyltransferase/cytidyltransferase family protein
MMP_RS08165		-1.7	-1.4	phosphoglycerate dehydrogenase
MMP_RS00720		-1.7	-5.3	metal-dependent hydrolase
MMP_RS01275		-1.7	-4.2	class III signal peptide-containing protein
MMP_RS00535		-1.7	-1.0	TIGR00375 family protein
MMP_RS03435		-1.7	-1.0	ketol-acid reductoisomerase
MMP_RS04720		-1.7	-1.7	DedA family protein
MMP_RS03450		-1.7	-1.5	glycine synthesis protein GlyXS (from data)
MMP_RS00040		-1.7	-3.1	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS05925		-1.7	-1.5	small nuclear ribonucleoprotein
MMP_RS08595		-1.6	-0.6	flagellar protein C
MMP_RS05985		-1.6	-1.6	hypothetical protein
MMP_RS00315		-1.6	-3.1	Nif3-like dinuclear metal center hexameric protein
MMP_RS00900		-1.6	-1.1	50S ribosomal protein L39e
MMP_RS03120		-1.6	-2.5	hypothetical protein
MMP_RS03125		-1.6	-3.9	cell division ATPase MinD
MMP_RS05540		-1.6	-2.5	hypothetical protein
MMP_RS01500		-1.6	-1.1	CBS domain-containing protein
MMP_RS03700		-1.6	-3.9	sodium:proton antiporter
MMP_RS02010		-1.6	-4.6	PHP domain-containing protein
MMP_RS01905		-1.6	-7.2	glycosyltransferase
MMP_RS01925		-1.5	-5.2	DUF1616 domain-containing protein
MMP_RS03110		-1.5	-2.5	glycosyltransferase family 2 protein
MMP_RS06340		-1.5	-3.5	phosphoadenosine phosphosulfate reductase family protein
MMP_RS06980		-1.5	-3.5	tRNA 2-thiocytidine biosynthesis TtcA family protein
MMP_RS06885		-1.5	-1.2	50S ribosome-binding GTPase
MMP_RS00685		-1.5	-1.9	2-phospho-L-lactate guanylyltransferase
MMP_RS07525		-1.5	-5.5	4Fe-4S binding protein
MMP_RS01720		-1.5	-1.2	replication factor C large subunit
MMP_RS03025		-1.5	-1.9	molybdenum cofactor guanylyltransferase
MMP_RS08940		-1.5	-0.7	MetS family NSS transporter small subunit
MMP_RS04780		-1.5	-1.7	ribonuclease P
MMP_RS00725		-1.5	-3.5	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS03095		-1.5	-3.6	diphthine synthase
MMP_RS02735		-1.4	-3.3	MBL fold metallo-hydrolase
MMP_RS02875		-1.4	-3.8	chorismate pyruvate-lyase family protein
MMP_RS07750		-1.4	-2.3	DUF357 domain-containing protein
MMP_RS05345		-1.4	-3.2	hypothetical protein
MMP_RS06120		-1.4	-0.9	UPF0147 family protein
MMP_RS05250		-1.4	-1.8	NFYB/HAP3 family transcription factor subunit
MMP_RS02235		-1.4	-5.0	CBS domain-containing protein
MMP_RS03080		-1.4	-2.1	universal stress protein
MMP_RS06725		-1.4	-4.6	hypothetical protein
MMP_RS04850		-1.4	-7.3	UPF0254 family protein
MMP_RS08645		-1.4	-3.7	UPF0179 family protein
MMP_RS01195		-1.4	-0.7	metalloregulator ArsR/SmtB family transcription factor
MMP_RS07620		-1.4	-2.6	energy-coupling factor ABC transporter substrate-binding protein
MMP_RS02345		-1.4	-1.9	GTP-dependent dephospho-CoA kinase family protein
MMP_RS03580		-1.4	-1.3	signal recognition particle-docking protein FtsY
MMP_RS01800		-1.3	-1.8	TIGR00303 family protein
MMP_RS04615		-1.3	-1.6	PDGLE domain-containing protein
MMP_RS01885		-1.3	-3.4	Gfo/Idh/MocA family oxidoreductase
MMP_RS04305		-1.3	-1.0	hypothetical protein
MMP_RS06485		-1.3	-0.5	zinc ribbon domain-containing protein
MMP_RS07820		-1.3	-2.5	UPF0104 family protein
MMP_RS01795		-1.3	-0.5	methanogenesis marker 6 protein
MMP_RS06130		-1.3	-1.7	peptidylprolyl isomerase
MMP_RS03485		-1.3	-2.6	TIGR00267 family protein
MMP_RS08600		-1.3	-1.2	flagellar protein D
MMP_RS01325		-1.3	-1.0	dihydroneopterin aldolase family protein
MMP_RS05450		-1.3	-2.2	CoB--CoM heterodisulfide reductase subunit C
MMP_RS04955		-1.2	-3.0	DNA topoisomerase I
MMP_RS05245		-1.2	-4.4	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS02930		-1.2	-2.0	class I SAM-dependent methyltransferase
MMP_RS08650		-1.2	-1.4	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS08590		-1.2	-1.9	flagellin
MMP_RS08745		-1.2	-3.1	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS08830		-1.2	-2.8	GTP-binding protein
MMP_RS03145		-1.2	-2.7	fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
MMP_RS01365		-1.2	-0.9	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS06900		-1.2	-1.3	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS07700		-1.2	-3.8	DUF1188 domain-containing protein
MMP_RS07615		-1.2	-2.2	energy-coupling factor ABC transporter permease
MMP_RS07685		-1.2	-3.7	TIGR01212 family radical SAM protein
MMP_RS04125		-1.2	-1.6	TetR/AcrR family transcriptional regulator
MMP_RS01085		-1.2	-0.9	hypothetical protein
MMP_RS07575		-1.2	-1.5	RNA ligase partner protein
MMP_RS03625		-1.2	-3.7	cell wall-binding protein
MMP_RS03385		-1.2	-0.5	cation diffusion facilitator family transporter
MMP_RS06270		-1.1	-2.0	TIGR00300 family protein
MMP_RS05445		-1.1	-3.9	CoB--CoM heterodisulfide reductase subunit B
MMP_RS06215		-1.1	-1.2	30S ribosomal protein S6e
MMP_RS03155		-1.1	-3.1	precorrin-6A reductase
MMP_RS08440		-1.1	-0.9	cell division protein SepF
MMP_RS03550		-1.1	-0.9	DUF2124 domain-containing protein
MMP_RS00060		-1.1	-0.9	3-dehydroquinate synthase II
MMP_RS03300		-1.1	-0.4	TOBE domain-containing protein
MMP_RS09055		-1.1	-0.5	CAP domain-containing protein
MMP_RS01020		-1.1	-0.5	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS06105		-1.1	-3.6	hydrogenase maturation peptidase HycI
MMP_RS08790		-1.1	-0.6	translation initiation factor IF-2 subunit alpha
MMP_RS07350		-1.1	-0.9	preprotein translocase subunit Sec61beta
MMP_RS02765		-1.1	-2.4	ABC transporter ATP-binding protein
MMP_RS01140		-1.1	-1.8	molybdate ABC transporter permease subunit
MMP_RS05955		-1.1	-1.0	CoB--CoM heterodisulfide reductase subunit C
MMP_RS02975		-1.1	-1.7	DUF2124 domain-containing protein
MMP_RS02245		-1.0	-1.2	hypothetical protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Dimetridazole across organisms