Experiment set12S302 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete Chlorpromazine hydrochloride 0.0333333333333333 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS03475 -5.7 -0.6 hypothetical protein compare
MMP_RS07005 -5.4 -0.5 4Fe-4S binding protein compare
MMP_RS02900 -5.3 -0.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS00695 -5.0 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01960 -4.8 -0.9 hypothetical protein compare
MMP_RS06895 -4.8 -1.4 selenocysteine-specific translation elongation factor compare
MMP_RS04890 -4.6 -0.6 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS00515 -4.3 -0.8 DUF655 domain-containing protein compare
MMP_RS03315 -4.0 -0.9 ferrous iron transport protein A compare
MMP_RS03640 -3.8 -3.1 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01795 -3.7 -1.4 methanogenesis marker 6 protein compare
MMP_RS03600 -3.6 -2.3 triose-phosphate isomerase compare
MMP_RS06120 -3.6 -1.8 UPF0147 family protein compare
MMP_RS04710 -3.6 -1.8 hypothetical protein compare
MMP_RS08720 -3.5 -1.5 4Fe-4S binding protein compare
MMP_RS03960 -3.5 -1.1 hypothetical protein compare
MMP_RS01545 -3.5 -1.0 CBS domain-containing protein compare
MMP_RS01265 -3.5 -3.4 hypothetical protein compare
MMP_RS07635 -3.4 -9.1 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS07555 -3.4 -0.7 monovalent cation/H+ antiporter subunit E compare
MMP_RS05920 -3.3 -0.6 50S ribosomal protein L37e compare
MMP_RS08675 -3.2 -2.5 class III signal peptide-containing protein compare
MMP_RS01225 -3.2 -4.7 DUF5379 domain-containing protein compare
MMP_RS00240 -3.2 -15.4 type II secretion system F family protein compare
MMP_RS08650 -3.1 -3.4 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS08860 -3.1 -5.0 MinD/ParA family protein compare
MMP_RS01270 -3.1 -17.0 prepilin peptidase compare
MMP_RS07390 -3.1 -2.3 cell division protein FtsZ compare
MMP_RS01275 -3.0 -6.5 class III signal peptide-containing protein compare
MMP_RS07380 -3.0 -1.9 transcription elongation factor Spt5 compare
MMP_RS00985 -2.9 -6.1 CDC48 family AAA ATPase compare
MMP_RS00245 -2.9 -20.4 type II secretion system F family protein compare
MMP_RS08635 -2.9 -1.8 UbiA family prenyltransferase compare
MMP_RS07075 -2.9 -3.6 phosphomannomutase/phosphoglucomutase compare
MMP_RS00250 -2.9 -16.8 Flp pilus assembly complex ATPase component TadA compare
MMP_RS02145 -2.9 -8.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS06350 -2.9 -6.5 HesA/MoeB/ThiF family protein compare
MMP_RS01285 -2.8 -12.7 hypothetical protein compare
MMP_RS05550 -2.8 -0.7 cation:proton antiporter compare
MMP_RS01610 -2.8 -3.3 hypothetical protein compare
MMP_RS05925 -2.8 -3.2 small nuclear ribonucleoprotein compare
MMP_RS05635 -2.8 -8.0 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS00300 -2.8 -0.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06230 -2.7 -2.4 helix-turn-helix domain-containing protein compare
MMP_RS08745 -2.7 -5.8 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS00110 -2.7 -2.8 hypothetical protein compare
MMP_RS01290 -2.7 -11.7 class III signal peptide-containing protein compare
MMP_RS01305 -2.7 -18.6 hypothetical protein compare
MMP_RS07845 -2.7 -2.7 LL-diaminopimelate aminotransferase compare
MMP_RS06630 -2.7 -0.7 UPF0058 family protein compare
MMP_RS08820 -2.7 -5.9 hypothetical protein compare
MMP_RS01085 -2.7 -1.7 hypothetical protein compare
MMP_RS06295 -2.7 -6.2 methanogenesis marker 14 protein compare
MMP_RS00810 -2.6 -6.7 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS01280 -2.6 -13.6 DUF515 domain-containing protein compare
MMP_RS08300 -2.6 -1.1 metal-sulfur cluster assembly factor compare
MMP_RS08210 -2.6 -2.2 phosphatidylglycerophosphatase A compare
MMP_RS08715 -2.6 -1.4 formylmethanofuran dehydrogenase subunit B compare
MMP_RS00040 -2.6 -5.1 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS07730 -2.6 -1.8 pyruvate synthase subunit beta compare
MMP_RS01295 -2.6 -9.5 hypothetical protein compare
MMP_RS08435 -2.6 -1.8 Era-like GTP-binding protein compare
MMP_RS07545 -2.5 -0.9 HTH domain-containing protein compare
MMP_RS03025 -2.5 -4.3 molybdenum cofactor guanylyltransferase compare
MMP_RS07330 -2.5 -16.3 membrane protein compare
MMP_RS01315 -2.5 -18.4 DUF2341 domain-containing protein compare
MMP_RS01310 -2.5 -15.8 hypothetical protein compare
MMP_RS05580 -2.5 -14.0 glycosyltransferase compare
MMP_RS01325 -2.5 -1.5 dihydroneopterin aldolase family protein compare
MMP_RS01925 -2.5 -6.2 DUF1616 domain-containing protein compare
MMP_RS01900 -2.5 -12.5 hypothetical protein compare
MMP_RS01380 -2.5 -4.1 PHP domain-containing protein compare
MMP_RS01905 -2.5 -11.7 glycosyltransferase compare
MMP_RS07710 -2.5 -6.3 cell division protein FtsZ compare
MMP_RS03700 -2.4 -6.7 sodium:proton antiporter compare
MMP_RS08790 -2.4 -1.7 translation initiation factor IF-2 subunit alpha compare
MMP_RS01175 -2.4 -3.6 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS07605 -2.4 -2.9 diadenylate cyclase compare
MMP_RS08855 -2.4 -9.7 hypothetical protein compare
MMP_RS02800 -2.4 -6.3 nucleotidyltransferase domain-containing protein compare
MMP_RS04900 -2.3 -14.9 hypothetical protein compare
MMP_RS09020 -2.3 -1.2 hypothetical protein compare
MMP_RS03125 -2.3 -4.6 cell division ATPase MinD compare
MMP_RS01755 -2.3 -1.3 DUF2097 domain-containing protein compare
MMP_RS06035 -2.2 -9.3 glycosyltransferase family 2 protein compare
MMP_RS01880 -2.2 -4.4 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS07355 -2.2 -0.8 transcription factor S compare
MMP_RS03435 -2.2 -1.7 ketol-acid reductoisomerase compare
MMP_RS06285 -2.1 -1.3 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS02195 -2.1 -2.6 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS04850 -2.1 -13.1 UPF0254 family protein compare
MMP_RS00725 -2.1 -5.4 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS00915 -2.1 -5.0 DUF116 domain-containing protein compare
MMP_RS03035 -2.1 -2.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS09045 -2.1 -13.2 class III signal peptide-containing protein compare
MMP_RS00315 -2.1 -5.2 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS00305 -2.1 -1.4 phosphoribosyl-ATP diphosphatase compare
MMP_RS06670 -2.1 -4.1 glucose-6-phosphate isomerase compare
MMP_RS01875 -2.1 -7.6 N-acetyltransferase compare
MMP_RS01500 -2.1 -1.6 CBS domain-containing protein compare
MMP_RS02240 -2.0 -2.3 methanogenesis marker 7 protein compare
MMP_RS00730 -2.0 -4.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS08195 -2.0 -8.4 hypothetical protein compare
MMP_RS03110 -2.0 -4.5 glycosyltransferase family 2 protein compare
MMP_RS02235 -2.0 -8.5 CBS domain-containing protein compare
MMP_RS01365 -2.0 -2.3 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS04720 -2.0 -2.4 DedA family protein compare
MMP_RS03080 -1.9 -2.3 universal stress protein compare
MMP_RS06885 -1.9 -2.2 50S ribosome-binding GTPase compare
MMP_RS07695 -1.9 -5.2 DUF3236 domain-containing protein compare
MMP_RS07600 -1.9 -1.9 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06340 -1.9 -6.3 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07575 -1.9 -3.3 RNA ligase partner protein compare
MMP_RS04685 -1.9 -2.0 DUF126 domain-containing protein compare
MMP_RS07700 -1.9 -7.5 DUF1188 domain-containing protein compare
MMP_RS02345 -1.9 -2.8 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS01910 -1.9 -7.4 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS06925 -1.8 -1.9 ribonuclease VapC4 compare
MMP_RS06625 -1.8 -1.5 DNA primase compare
MMP_RS06725 -1.8 -7.2 hypothetical protein compare
MMP_RS01195 -1.8 -1.0 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06600 -1.8 -1.1 class III signal peptide-containing protein compare
MMP_RS07385 -1.8 -1.5 protein translocase SEC61 complex subunit gamma compare
MMP_RS00735 -1.8 -3.7 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS01020 -1.8 -0.9 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS03445 -1.8 -0.8 methanogenesis marker 17 protein compare
MMP_RS08440 -1.8 -1.8 cell division protein SepF compare
MMP_RS03015 -1.7 -5.6 GTP 3' 8-cyclase MoaA compare
MMP_RS06395 -1.7 -2.7 ThiF family adenylyltransferase compare
MMP_RS04780 -1.7 -1.9 ribonuclease P compare
MMP_RS05930 -1.7 -1.4 3-isopropylmalate dehydratase large subunit compare
MMP_RS07750 -1.7 -5.9 DUF357 domain-containing protein compare
MMP_RS00685 -1.7 -2.6 2-phospho-L-lactate guanylyltransferase compare
MMP_RS04775 -1.7 -2.4 adenosylhomocysteinase compare
MMP_RS04585 -1.7 -6.0 AIR synthase related protein compare
MMP_RS07875 -1.7 -3.3 hypothetical protein compare
MMP_RS05345 -1.7 -4.8 hypothetical protein compare
MMP_RS06355 -1.7 -1.6 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS08645 -1.7 -4.0 UPF0179 family protein compare
MMP_RS06980 -1.7 -5.5 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS00140 -1.7 -4.6 DUF192 domain-containing protein compare
MMP_RS06020 -1.7 -3.9 archaeoflavoprotein AfpA compare
MMP_RS05555 -1.7 -1.0 DUF4040 domain-containing protein compare
MMP_RS01885 -1.7 -3.5 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01800 -1.6 -2.4 TIGR00303 family protein compare
MMP_RS07630 -1.6 -1.1 ATP-binding cassette domain-containing protein compare
MMP_RS01915 -1.6 -8.3 DUF354 domain-containing protein compare
MMP_RS03580 -1.6 -2.2 signal recognition particle-docking protein FtsY compare
MMP_RS07955 -1.6 -3.1 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06535 -1.5 -2.8 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS05640 -1.5 -4.3 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS03385 -1.5 -0.8 cation diffusion facilitator family transporter compare
MMP_RS05425 -1.5 -3.6 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS08155 -1.5 -4.2 hypothetical protein compare
MMP_RS05540 -1.5 -2.7 hypothetical protein compare
MMP_RS00325 -1.5 -1.2 RNA-binding protein compare
MMP_RS07090 -1.5 -5.1 tRNA (adenine-N1)-methyltransferase compare
MMP_RS04125 -1.5 -1.7 TetR/AcrR family transcriptional regulator compare
MMP_RS09055 -1.5 -0.7 CAP domain-containing protein compare
MMP_RS01005 -1.5 -0.7 riboflavin synthase compare
MMP_RS07445 -1.5 -3.2 helix-turn-helix domain-containing protein compare
MMP_RS07525 -1.5 -4.4 4Fe-4S binding protein compare
MMP_RS02280 -1.5 -0.4 DUF211 domain-containing protein compare
MMP_RS01725 -1.5 -2.3 class I SAM-dependent methyltransferase family protein compare
MMP_RS05250 -1.4 -2.0 NFYB/HAP3 family transcription factor subunit compare
MMP_RS01220 -1.4 -3.5 hypothetical protein compare
MMP_RS05245 -1.4 -5.6 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS08330 -1.4 -3.7 NADH-quinone oxidoreductase subunit H compare
MMP_RS01895 -1.4 -6.7 flippase compare
MMP_RS08830 -1.4 -3.3 GTP-binding protein compare
MMP_RS05910 -1.4 -2.3 cell division ATPase MinD compare
MMP_RS01970 -1.4 -5.8 TIGR04279 domain-containing protein compare
MMP_RS06310 -1.4 -3.1 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS00115 -1.4 -6.9 radical SAM protein compare
MMP_RS03250 -1.3 -1.8 MJ1244 family protein compare
MMP_RS03390 -1.3 -4.7 malate dehydrogenase compare
MMP_RS00720 -1.3 -4.3 metal-dependent hydrolase compare
MMP_RS05430 -1.3 -4.0 TIGR00288 family NYN domain-containing protein compare
MMP_RS05515 -1.3 -4.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS03020 -1.3 -2.7 peptidylprolyl isomerase compare
MMP_RS07420 -1.3 -3.3 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06865 -1.3 -1.3 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS07735 -1.3 -0.5 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS01840 -1.3 -3.9 TIGR00289 family protein compare
MMP_RS01745 -1.2 -3.0 AMP phosphorylase compare
MMP_RS07200 -1.2 -3.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS07425 -1.2 -2.7 GTP-binding protein compare
MMP_RS01240 -1.2 -1.0 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS01255 -1.2 -1.7 amino acid ABC transporter ATP-binding protein compare
MMP_RS06105 -1.2 -3.9 hydrogenase maturation peptidase HycI compare
MMP_RS07580 -1.2 -1.5 DUF356 domain-containing protein compare
MMP_RS04615 -1.2 -2.0 PDGLE domain-containing protein compare
MMP_RS05865 -1.2 -1.4 hypothetical protein compare
MMP_RS04955 -1.2 -2.7 DNA topoisomerase I compare
MMP_RS01665 -1.2 -2.5 DUF2111 domain-containing protein compare
MMP_RS00570 -1.2 -1.3 protein-L-isoaspartate O-methyltransferase compare
MMP_RS08940 -1.2 -0.8 MetS family NSS transporter small subunit compare
MMP_RS00295 -1.2 -1.5 gamma carbonic anhydrase family protein compare
MMP_RS00895 -1.1 -2.0 hypothetical protein compare
MMP_RS07190 -1.1 -3.8 chromosome segregation protein SMC compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Chlorpromazine hydrochloride across organisms