Experiment set12S297 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete metronidazole 0.00833333333333333 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS07545 -4.9 -0.7 HTH domain-containing protein compare
MMP_RS04780 -4.1 -2.8 ribonuclease P compare
MMP_RS06120 -3.9 -1.5 UPF0147 family protein compare
MMP_RS07845 -3.8 -2.5 LL-diaminopimelate aminotransferase compare
MMP_RS00515 -3.8 -0.7 DUF655 domain-containing protein compare
MMP_RS08720 -3.6 -1.4 4Fe-4S binding protein compare
MMP_RS03400 -3.6 -2.1 archease compare
MMP_RS03435 -3.2 -1.5 ketol-acid reductoisomerase compare
MMP_RS03315 -3.2 -0.9 ferrous iron transport protein A compare
MMP_RS00695 -3.2 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00520 -3.1 -1.2 RNA polymerase Rpb4 family protein compare
MMP_RS08820 -3.0 -4.1 hypothetical protein compare
MMP_RS07005 -3.0 -0.5 4Fe-4S binding protein compare
MMP_RS07635 -2.9 -7.2 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS04890 -2.9 -0.7 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS08790 -2.8 -1.6 translation initiation factor IF-2 subunit alpha compare
MMP_RS06400 -2.7 -1.1 4Fe-4S binding protein compare
MMP_RS01225 -2.7 -4.1 DUF5379 domain-containing protein compare
MMP_RS01755 -2.7 -1.0 DUF2097 domain-containing protein compare
MMP_RS03025 -2.7 -4.8 molybdenum cofactor guanylyltransferase compare
MMP_RS01020 -2.6 -0.9 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01545 -2.6 -0.9 CBS domain-containing protein compare
MMP_RS04720 -2.5 -2.2 DedA family protein compare
MMP_RS06895 -2.5 -1.1 selenocysteine-specific translation elongation factor compare
MMP_RS06285 -2.5 -1.4 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS08435 -2.5 -1.7 Era-like GTP-binding protein compare
MMP_RS05920 -2.5 -0.5 50S ribosomal protein L37e compare
MMP_RS06020 -2.4 -3.0 archaeoflavoprotein AfpA compare
MMP_RS01830 -2.4 -1.2 tRNA-Val compare
MMP_RS08745 -2.4 -5.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS03445 -2.4 -0.8 methanogenesis marker 17 protein compare
MMP_RS04900 -2.4 -17.7 hypothetical protein compare
MMP_RS05515 -2.4 -6.5 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS01085 -2.4 -1.5 hypothetical protein compare
MMP_RS01380 -2.4 -3.8 PHP domain-containing protein compare
MMP_RS06350 -2.4 -5.2 HesA/MoeB/ThiF family protein compare
MMP_RS08300 -2.4 -0.9 metal-sulfur cluster assembly factor compare
MMP_RS01290 -2.4 -9.5 class III signal peptide-containing protein compare
MMP_RS04775 -2.3 -2.3 adenosylhomocysteinase compare
MMP_RS07200 -2.3 -4.9 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS00730 -2.3 -5.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS01795 -2.3 -1.0 methanogenesis marker 6 protein compare
MMP_RS06900 -2.3 -1.9 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS04090 -2.3 -2.2 hypothetical protein compare
MMP_RS06730 -2.3 -1.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS05250 -2.2 -3.0 NFYB/HAP3 family transcription factor subunit compare
MMP_RS05295 -2.2 -9.6 minichromosome maintenance protein MCM compare
MMP_RS01175 -2.2 -3.1 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06295 -2.2 -6.3 methanogenesis marker 14 protein compare
MMP_RS00250 -2.2 -15.5 Flp pilus assembly complex ATPase component TadA compare
MMP_RS03035 -2.2 -2.6 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS00245 -2.2 -15.7 type II secretion system F family protein compare
MMP_RS06600 -2.2 -1.0 class III signal peptide-containing protein compare
MMP_RS08650 -2.2 -2.3 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01305 -2.2 -14.6 hypothetical protein compare
MMP_RS07630 -2.1 -1.1 ATP-binding cassette domain-containing protein compare
MMP_RS08195 -2.1 -7.5 hypothetical protein compare
MMP_RS08675 -2.1 -2.4 class III signal peptide-containing protein compare
MMP_RS02800 -2.1 -5.7 nucleotidyltransferase domain-containing protein compare
MMP_RS07330 -2.1 -13.9 membrane protein compare
MMP_RS08460 -2.1 -1.7 proteasome-activating nucleotidase compare
MMP_RS04955 -2.1 -5.7 DNA topoisomerase I compare
MMP_RS00240 -2.1 -11.7 type II secretion system F family protein compare
MMP_RS03245 -2.1 -2.9 DNA repair and recombination protein RadB compare
MMP_RS01280 -2.1 -10.1 DUF515 domain-containing protein compare
MMP_RS07755 -2.1 -1.0 DUF555 domain-containing protein compare
MMP_RS07600 -2.1 -1.8 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS02145 -2.1 -3.8 winged helix-turn-helix transcriptional regulator compare
MMP_RS05965 -2.1 -2.7 carboxymuconolactone decarboxylase family protein compare
MMP_RS01310 -2.1 -12.8 hypothetical protein compare
MMP_RS00985 -2.1 -4.6 CDC48 family AAA ATPase compare
MMP_RS00810 -2.1 -5.0 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS04710 -2.1 -1.3 hypothetical protein compare
MMP_RS07750 -2.1 -3.9 DUF357 domain-containing protein compare
MMP_RS00685 -2.1 -2.7 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01220 -2.0 -6.0 hypothetical protein compare
MMP_RS03475 -2.0 -0.5 hypothetical protein compare
MMP_RS00300 -2.0 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS05635 -2.0 -6.9 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS03015 -2.0 -8.6 GTP 3' 8-cyclase MoaA compare
MMP_RS07075 -2.0 -3.4 phosphomannomutase/phosphoglucomutase compare
MMP_RS06355 -2.0 -1.7 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01270 -2.0 -12.0 prepilin peptidase compare
MMP_RS01285 -2.0 -9.1 hypothetical protein compare
MMP_RS06885 -1.9 -2.1 50S ribosome-binding GTPase compare
MMP_RS07355 -1.9 -0.6 transcription factor S compare
MMP_RS01885 -1.9 -5.1 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS03125 -1.9 -4.1 cell division ATPase MinD compare
MMP_RS00735 -1.9 -2.7 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS05815 -1.9 -1.5 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS00040 -1.9 -4.3 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS03080 -1.9 -2.5 universal stress protein compare
MMP_RS06035 -1.9 -7.8 glycosyltransferase family 2 protein compare
MMP_RS03580 -1.9 -2.3 signal recognition particle-docking protein FtsY compare
MMP_RS06395 -1.9 -2.5 ThiF family adenylyltransferase compare
MMP_RS06340 -1.9 -4.9 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS01905 -1.9 -8.9 glycosyltransferase compare
MMP_RS01265 -1.9 -2.8 hypothetical protein compare
MMP_RS02355 -1.8 -2.1 30S ribosomal protein S27ae compare
MMP_RS08860 -1.8 -4.4 MinD/ParA family protein compare
MMP_RS00110 -1.8 -2.0 hypothetical protein compare
MMP_RS07710 -1.8 -4.8 cell division protein FtsZ compare
MMP_RS02240 -1.8 -1.4 methanogenesis marker 7 protein compare
MMP_RS05925 -1.8 -2.4 small nuclear ribonucleoprotein compare
MMP_RS06315 -1.8 -0.6 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS02345 -1.8 -2.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS02135 -1.8 -3.6 DUF5612 domain-containing protein compare
MMP_RS03110 -1.8 -3.8 glycosyltransferase family 2 protein compare
MMP_RS03700 -1.7 -5.4 sodium:proton antiporter compare
MMP_RS01725 -1.7 -3.1 class I SAM-dependent methyltransferase family protein compare
MMP_RS02195 -1.7 -2.4 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS05345 -1.7 -4.9 hypothetical protein compare
MMP_RS01005 -1.7 -0.8 riboflavin synthase compare
MMP_RS01315 -1.7 -13.7 DUF2341 domain-containing protein compare
MMP_RS01295 -1.7 -7.9 hypothetical protein compare
MMP_RS00725 -1.7 -6.3 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS05550 -1.7 -0.5 cation:proton antiporter compare
MMP_RS07380 -1.7 -1.4 transcription elongation factor Spt5 compare
MMP_RS05580 -1.7 -8.5 glycosyltransferase compare
MMP_RS01900 -1.7 -7.3 hypothetical protein compare
MMP_RS08210 -1.7 -1.7 phosphatidylglycerophosphatase A compare
MMP_RS08370 -1.7 -0.4 cation:proton antiporter subunit C compare
MMP_RS02010 -1.6 -4.4 PHP domain-containing protein compare
MMP_RS09020 -1.6 -1.1 hypothetical protein compare
MMP_RS08855 -1.6 -6.8 hypothetical protein compare
MMP_RS03600 -1.6 -1.3 triose-phosphate isomerase compare
MMP_RS04685 -1.6 -1.8 DUF126 domain-containing protein compare
MMP_RS06670 -1.6 -3.1 glucose-6-phosphate isomerase compare
MMP_RS06725 -1.6 -5.5 hypothetical protein compare
MMP_RS06925 -1.6 -1.7 ribonuclease VapC4 compare
MMP_RS01925 -1.6 -3.7 DUF1616 domain-containing protein compare
MMP_RS08660 -1.6 -5.3 DHH family phosphoesterase compare
MMP_RS05245 -1.5 -6.5 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS08600 -1.5 -1.9 flagellar protein D compare
MMP_RS04585 -1.5 -7.2 AIR synthase related protein compare
MMP_RS05845 -1.5 -1.1 tRNA-intron lyase compare
MMP_RS06290 -1.5 -3.1 DNA repair and recombination protein RadA compare
MMP_RS07555 -1.5 -0.5 monovalent cation/H+ antiporter subunit E compare
MMP_RS00915 -1.5 -3.9 DUF116 domain-containing protein compare
MMP_RS01195 -1.5 -0.8 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01880 -1.5 -2.6 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS04615 -1.5 -2.5 PDGLE domain-containing protein compare
MMP_RS03960 -1.5 -0.8 hypothetical protein compare
MMP_RS07575 -1.5 -2.2 RNA ligase partner protein compare
MMP_RS07605 -1.5 -2.3 diadenylate cyclase compare
MMP_RS01800 -1.4 -2.2 TIGR00303 family protein compare
MMP_RS03640 -1.4 -2.8 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS07525 -1.4 -5.1 4Fe-4S binding protein compare
MMP_RS05425 -1.4 -2.2 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS04850 -1.4 -7.8 UPF0254 family protein compare
MMP_RS02875 -1.4 -3.4 chorismate pyruvate-lyase family protein compare
MMP_RS05265 -1.4 -1.4 2-isopropylmalate synthase compare
MMP_RS00720 -1.4 -2.9 metal-dependent hydrolase compare
MMP_RS06980 -1.4 -5.1 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS02805 -1.4 -0.7 HEPN domain-containing protein compare
MMP_RS02340 -1.3 -1.4 DNA-directed RNA polymerase subunit E'' compare
MMP_RS08165 -1.3 -1.6 phosphoglycerate dehydrogenase compare
MMP_RS03550 -1.3 -1.0 DUF2124 domain-containing protein compare
MMP_RS09045 -1.3 -6.8 class III signal peptide-containing protein compare
MMP_RS03440 -1.3 -0.6 MoaD/ThiS family protein compare
MMP_RS07875 -1.3 -3.1 hypothetical protein compare
MMP_RS05535 -1.3 -3.0 hypothetical protein compare
MMP_RS07695 -1.3 -4.3 DUF3236 domain-containing protein compare
MMP_RS07700 -1.3 -5.3 DUF1188 domain-containing protein compare
MMP_RS07730 -1.3 -0.9 pyruvate synthase subunit beta compare
MMP_RS05540 -1.3 -2.0 hypothetical protein compare
MMP_RS01915 -1.3 -5.7 DUF354 domain-containing protein compare
MMP_RS00750 -1.3 -1.1 fumarate hydratase compare
MMP_RS07350 -1.2 -1.2 preprotein translocase subunit Sec61beta compare
MMP_RS05640 -1.2 -3.2 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS08635 -1.2 -0.9 UbiA family prenyltransferase compare
MMP_RS07390 -1.2 -1.3 cell division protein FtsZ compare
MMP_RS06230 -1.2 -1.5 helix-turn-helix domain-containing protein compare
MMP_RS07385 -1.2 -1.1 protein translocase SEC61 complex subunit gamma compare
MMP_RS04255 -1.2 -3.3 coenzyme F420 hydrogenase subunit beta compare
MMP_RS01890 -1.2 -1.1 nucleotide sugar dehydrogenase compare
MMP_RS03155 -1.2 -3.6 precorrin-6A reductase compare
MMP_RS03205 -1.2 -0.7 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS00315 -1.2 -3.7 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01875 -1.2 -2.9 N-acetyltransferase compare
MMP_RS07955 -1.2 -2.6 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS08595 -1.2 -0.5 flagellar protein C compare
MMP_RS00310 -1.2 -5.1 CBS domain-containing protein compare
MMP_RS00060 -1.2 -1.1 3-dehydroquinate synthase II compare
MMP_RS01500 -1.2 -1.2 CBS domain-containing protein compare
MMP_RS03095 -1.2 -3.0 diphthine synthase compare
MMP_RS02235 -1.2 -4.4 CBS domain-containing protein compare
MMP_RS00325 -1.2 -0.9 RNA-binding protein compare
MMP_RS07420 -1.1 -2.8 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01600 -1.1 -1.8 50S ribosomal protein L15e compare
MMP_RS08440 -1.1 -1.1 cell division protein SepF compare
MMP_RS01180 -1.1 -1.2 XTP/dITP diphosphatase compare
MMP_RS07625 -1.1 -1.6 cobalt ECF transporter T component CbiQ compare
MMP_RS05910 -1.1 -1.8 cell division ATPase MinD compare
MMP_RS04695 -1.1 -3.2 selenide water dikinase SelD compare
MMP_RS06865 -1.1 -1.7 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS03250 -1.1 -1.6 MJ1244 family protein compare
MMP_RS02280 -1.1 -0.3 DUF211 domain-containing protein compare
MMP_RS08940 -1.1 -0.7 MetS family NSS transporter small subunit compare
MMP_RS08645 -1.1 -3.5 UPF0179 family protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Metronidazole across organisms