Experiment set12S295 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS00305		-6.3	-2.0	phosphoribosyl-ATP diphosphatase
MMP_RS00300		-5.9	-0.8	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS03300		-5.8	-0.8	TOBE domain-containing protein
MMP_RS03475		-5.4	-0.7	hypothetical protein
MMP_RS08370		-5.3	-0.7	cation:proton antiporter subunit C
MMP_RS07005		-5.3	-0.7	4Fe-4S binding protein
MMP_RS06630		-4.8	-0.9	UPF0058 family protein
MMP_RS07735		-3.4	-0.9	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS06525		-2.4	-1.4	YciI family protein
MMP_RS02900		-2.1	-0.6	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS06840		-1.6	-1.1	DNA-directed RNA polymerase subunit N
MMP_RS01795		-1.5	-1.2	methanogenesis marker 6 protein
MMP_RS03960		-1.5	-1.1	hypothetical protein
MMP_RS02190		-1.4	-1.2	sulfopyruvate decarboxylase subunit alpha
MMP_RS06975		-1.3	-0.7	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS01265		-1.3	-3.3	hypothetical protein
MMP_RS04710		-1.3	-0.8	hypothetical protein
MMP_RS08615		-1.2	-1.0	flagellar protein G
MMP_RS08760		-1.2	-2.5	hypothetical protein
MMP_RS02955		-1.2	-1.7	DJ-1/PfpI family protein
MMP_RS01385		-1.1	-0.5	imidazole glycerol phosphate synthase subunit HisH
MMP_RS00520		-1.1	-0.9	RNA polymerase Rpb4 family protein
MMP_RS05910		-0.9	-1.6	cell division ATPase MinD
MMP_RS01180		-0.9	-1.5	XTP/dITP diphosphatase
MMP_RS01470		-0.9	-1.3	ATP-binding cassette domain-containing protein
MMP_RS07600		-0.9	-0.9	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS04310		-0.9	-2.1	hypothetical protein
MMP_RS04685		-0.9	-1.6	DUF126 domain-containing protein
MMP_RS08595		-0.9	-0.7	flagellar protein C
MMP_RS06900		-0.9	-0.6	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS03440		-0.9	-0.6	MoaD/ThiS family protein
MMP_RS01100		-0.9	-0.6	ABC transporter ATP-binding protein
MMP_RS03550		-0.9	-1.3	DUF2124 domain-containing protein
MMP_RS08940		-0.8	-0.9	MetS family NSS transporter small subunit
MMP_RS02765		-0.8	-1.6	ABC transporter ATP-binding protein
MMP_RS02045		-0.8	-0.9	tRNA-Met
MMP_RS05065		-0.8	-2.1	CooT family nickel-binding protein
MMP_RS01495		-0.8	-2.7	TraB/GumN family protein
MMP_RS06590		-0.8	-1.6	GNAT family N-acetyltransferase
MMP_RS08400		-0.8	-0.9	MJ0307 family thioredoxin
MMP_RS01080		-0.8	-1.8	DUF2202 domain-containing protein
MMP_RS03590		-0.7	-1.9	METTL5 family protein
MMP_RS08230		-0.7	-2.1	50S ribosomal protein L11 methyltransferase
MMP_RS01685		-0.7	-1.3	indolepyruvate oxidoreductase subunit beta
MMP_RS00750		-0.7	-0.8	fumarate hydratase
MMP_RS03125		-0.7	-1.3	cell division ATPase MinD
MMP_RS06720		-0.7	-2.4	response regulator transcription factor
MMP_RS06495		-0.7	-1.1	YkgJ family cysteine cluster protein
MMP_RS01790		-0.7	-1.6	restriction endonuclease
MMP_RS02800		-0.7	-2.1	nucleotidyltransferase domain-containing protein
MMP_RS08830		-0.7	-1.4	GTP-binding protein
MMP_RS07960		-0.7	-2.0	sugar phosphate isomerase/epimerase
MMP_RS01890		-0.7	-1.6	nucleotide sugar dehydrogenase
MMP_RS02985		-0.7	-1.3	hypothetical protein
MMP_RS06940		-0.7	-1.5	polyprenyl diphosphate synthase
MMP_RS05420		-0.7	-1.8	DUF61 family protein
MMP_RS06485		-0.7	-0.5	zinc ribbon domain-containing protein
MMP_RS02700		-0.7	-1.9	formylmethanofuran dehydrogenase subunit C
MMP_RS00110		-0.6	-0.5	hypothetical protein
MMP_RS00695		-0.6	-0.5	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS08390		-0.6	-1.0	DUF5400 domain-containing protein
MMP_RS01960		-0.6	-0.4	hypothetical protein
MMP_RS01110		-0.6	-1.0	FmdE family protein
MMP_RS08340		-0.6	-1.4	4Fe-4S binding protein
MMP_RS06215		-0.6	-1.2	30S ribosomal protein S6e
MMP_RS02010		-0.6	-2.8	PHP domain-containing protein
MMP_RS02745		-0.6	-1.1	hypothetical protein
MMP_RS04615		-0.6	-1.2	PDGLE domain-containing protein
MMP_RS02790		-0.6	-0.5	class III signal peptide-containing protein
MMP_RS07845		-0.6	-1.0	LL-diaminopimelate aminotransferase
MMP_RS03070		-0.6	-1.7	AzlD domain-containing protein
MMP_RS08360		-0.6	-0.8	hypothetical protein
MMP_RS01320		-0.6	-1.2	hypothetical protein
MMP_RS04610		-0.6	-1.0	Dabb family protein
MMP_RS08820		-0.6	-1.6	hypothetical protein
MMP_RS02255		-0.6	-1.8	hypothetical protein
MMP_RS01525		-0.6	-0.8	nucleoside-diphosphate kinase
MMP_RS07725		-0.6	-1.0	4Fe-4S dicluster domain-containing protein
MMP_RS06715		-0.6	-3.3	cache domain-containing protein
MMP_RS04305		-0.6	-1.0	hypothetical protein
MMP_RS00640		-0.6	-2.4	ABC transporter substrate-binding protein
MMP_RS01195		-0.6	-0.6	metalloregulator ArsR/SmtB family transcription factor
MMP_RS01085		-0.5	-0.9	hypothetical protein
MMP_RS04265		-0.5	-1.2	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS01310		-0.5	-3.0	hypothetical protein
MMP_RS00335		-0.5	-1.1	5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase CofH
MMP_RS00665		-0.5	-0.7	hypothetical protein
MMP_RS06370		-0.5	-1.1	biotin synthase BioB
MMP_RS03270		-0.5	-1.3	ADP-ribosylglycohydrolase family protein
MMP_RS01720		-0.5	-0.5	replication factor C large subunit
MMP_RS04875		-0.5	-0.9	energy-converting hydrogenase B subunit P
MMP_RS03080		-0.5	-1.3	universal stress protein
MMP_RS06530		-0.5	-1.4	bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
MMP_RS05940		-0.5	-1.0	corrinoid protein
MMP_RS02910		-0.5	-1.2	ABC transporter substrate-binding protein
MMP_RS03335		-0.5	-1.8	ABC transporter permease
MMP_RS05110		-0.5	-1.1	16S ribosomal RNA methyltransferase A
MMP_RS05505		-0.5	-1.6	class IV adenylate cyclase
MMP_RS08240		-0.5	-1.8	methanogenesis marker 16 metalloprotein
MMP_RS03490		-0.5	-0.6	DUF2115 domain-containing protein
MMP_RS07915		-0.5	-1.7	DUF4870 domain-containing protein
MMP_RS02935		-0.5	-1.1	A24 family peptidase
MMP_RS06760		-0.5	-0.7	hypothetical protein
MMP_RS01220		-0.5	-1.4	hypothetical protein
MMP_RS08690		-0.5	-2.4	RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
MMP_RS07095		-0.5	-0.9	PspC domain-containing protein
MMP_RS00700		-0.5	-2.4	OB-fold nucleic acid binding domain-containing protein
MMP_RS01260		-0.5	-0.9	HDIG domain-containing protein
MMP_RS02000		-0.5	-1.6	radical SAM protein
MMP_RS07625		-0.5	-0.5	cobalt ECF transporter T component CbiQ
MMP_RS01990		-0.5	-0.6	hypothetical protein
MMP_RS02310		-0.5	-0.7	RimK-like ATPgrasp N-terminal domain-containing protein
MMP_RS00240		-0.5	-2.5	type II secretion system F family protein
MMP_RS00285		-0.5	-1.7	TIGR04013 family B12-binding domain/radical SAM domain-containing protein
MMP_RS00810		-0.4	-1.3	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS01380		-0.4	-1.1	PHP domain-containing protein
MMP_RS06560		-0.4	-1.8	hypothetical protein
MMP_RS00965		-0.4	-1.1	hypothetical protein
MMP_RS01290		-0.4	-2.1	class III signal peptide-containing protein
MMP_RS04060		-0.4	-1.2	hypothetical protein
MMP_RS05440		-0.4	-1.3	winged helix-turn-helix transcriptional regulator
MMP_RS06600		-0.4	-0.4	class III signal peptide-containing protein
MMP_RS06105		-0.4	-1.5	hydrogenase maturation peptidase HycI
MMP_RS01745		-0.4	-1.6	AMP phosphorylase
MMP_RS00675		-0.4	-0.3	nitroreductase family protein
MMP_RS06735		-0.4	-1.2	class I SAM-dependent rRNA methyltransferase
MMP_RS07645		-0.4	-1.1	aldehyde dehydrogenase family protein
MMP_RS08725		-0.4	-0.4	Ni/Fe hydrogenase subunit alpha
MMP_RS08580		-0.4	-0.5	flagellin
MMP_RS08650		-0.4	-0.7	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS06745		-0.4	-1.0	DUF2119 domain-containing protein
MMP_RS02975		-0.4	-1.3	DUF2124 domain-containing protein
MMP_RS00975		-0.4	-1.9	HD domain-containing protein
MMP_RS00035		-0.4	-2.3	DUF2098 family protein
MMP_RS04165		-0.4	-0.5	TetR/AcrR family transcriptional regulator
MMP_RS05445		-0.4	-1.5	CoB--CoM heterodisulfide reductase subunit B
MMP_RS05115		-0.4	-1.5	50S ribosomal protein L11 methyltransferase
MMP_RS06520		-0.4	-1.2	DUF1786 domain-containing protein
MMP_RS02240		-0.4	-0.5	methanogenesis marker 7 protein
MMP_RS02880		-0.4	-1.6	AmmeMemoRadiSam system radical SAM enzyme
MMP_RS01305		-0.4	-2.7	hypothetical protein
MMP_RS02530		-0.4	-1.5	type II toxin-antitoxin system mRNA interferase toxin RelE/StbE family
MMP_RS05900		-0.4	-1.3	tetratricopeptide repeat protein
MMP_RS01460		-0.4	-0.8	hypothetical protein
MMP_RS07190		-0.4	-1.4	chromosome segregation protein SMC
MMP_RS01270		-0.4	-2.3	prepilin peptidase
MMP_RS08665		-0.4	-2.4	hypothetical protein
MMP_RS07770		-0.4	-1.9	alanine racemase
MMP_RS07410		-0.4	-1.5	4-demethylwyosine synthase TYW1
MMP_RS04255		-0.4	-1.3	coenzyme F420 hydrogenase subunit beta
MMP_RS00150		-0.4	-1.1	AAA family ATPase
MMP_RS05680		-0.4	-1.7	phosphate signaling complex protein PhoU
MMP_RS01295		-0.4	-1.9	hypothetical protein
MMP_RS00295		-0.4	-0.6	gamma carbonic anhydrase family protein
MMP_RS04335		-0.4	-1.9	GTP-binding protein
MMP_RS03250		-0.4	-0.4	MJ1244 family protein
MMP_RS05280		-0.4	-1.4	COG1361 S-layer family protein
MMP_RS04125		-0.4	-0.8	TetR/AcrR family transcriptional regulator
MMP_RS03800		-0.4	-0.7	hypothetical protein
MMP_RS04195		-0.3	-0.9	flavodoxin
MMP_RS07390		-0.3	-0.4	cell division protein FtsZ
MMP_RS00570		-0.3	-0.9	protein-L-isoaspartate O-methyltransferase
MMP_RS08105		-0.3	-1.1	6-carboxyhexanoate--CoA ligase
MMP_RS01045		-0.3	-1.1	diphthamide biosynthesis enzyme Dph2
MMP_RS00555		-0.3	-1.3	MFS transporter
MMP_RS06705		-0.3	-0.9	formate/nitrite transporter family protein
MMP_RS08930		-0.3	-0.3	hypothetical protein
MMP_RS02020		-0.3	-0.9	gamma-glutamylcyclotransferase
MMP_RS00250		-0.3	-2.3	Flp pilus assembly complex ATPase component TadA
MMP_RS08160		-0.3	-0.9	EamA family transporter
MMP_RS01315		-0.3	-2.6	DUF2341 domain-containing protein
MMP_RS08315		-0.3	-0.5	S-methyl-5-thioribose-1-phosphate isomerase
MMP_RS00450		-0.3	-0.3	4Fe-4S binding protein
MMP_RS06110		-0.3	-0.6	ATP-dependent protease LonB
MMP_RS06340		-0.3	-1.2	phosphoadenosine phosphosulfate reductase family protein
MMP_RS03470		-0.3	-1.2	phosphoadenosine phosphosulfate reductase family protein
MMP_RS06225		-0.3	-1.0	DNA double-strand break repair nuclease NurA
MMP_RS03155		-0.3	-0.9	precorrin-6A reductase
MMP_RS08715		-0.3	-0.3	formylmethanofuran dehydrogenase subunit B
MMP_RS01075		-0.3	-0.3	hypothetical protein
MMP_RS07855		-0.3	-1.1	class I SAM-dependent methyltransferase
MMP_RS05130		-0.3	-2.0	DUF2226 domain-containing protein
MMP_RS06905		-0.3	-0.7	hypothetical protein
MMP_RS07605		-0.3	-0.7	diadenylate cyclase
MMP_RS05310		-0.3	-1.0	hypothetical protein
MMP_RS00245		-0.3	-2.2	type II secretion system F family protein
MMP_RS07820		-0.3	-0.7	UPF0104 family protein
MMP_RS05090		-0.3	-1.2	CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta
MMP_RS04740		-0.3	-0.8	DUF473 domain-containing protein
MMP_RS00540		-0.3	-1.4	PLP-dependent aminotransferase family protein
MMP_RS01225		-0.3	-0.8	DUF5379 domain-containing protein
MMP_RS05950		-0.3	-1.3	nickel-dependent hydrogenase large subunit
MMP_RS06435		-0.3	-0.6	CBS domain-containing protein
MMP_RS02695		-0.3	-0.8	formylmethanofuran dehydrogenase subunit A
MMP_RS03685		-0.3	-1.0	Mrp/NBP35 family ATP-binding protein
MMP_RS08675		-0.3	-0.5	class III signal peptide-containing protein
MMP_RS06970		-0.3	-0.9	ribosomal protein S18-alanine N-acetyltransferase
MMP_RS03095		-0.3	-1.1	diphthine synthase
MMP_RS08845		-0.3	-0.9	archaellum operon transcriptional activator EarA family protein
MMP_RS02840		-0.3	-0.8	DUF123 domain-containing protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Sodium Chlorite across organisms