Experiment set12IT085 for Pseudomonas fluorescens FW300-N2E2

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With vitamins, timepoint 1

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_71 -4.5 -3.1 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_5177 -4.1 -7.7 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_2258 -4.1 -5.5 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3751 -3.9 -10.1 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3782 -3.9 -7.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4279 -3.9 -12.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3842 -3.8 -2.6 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4048 -3.7 -5.6 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4564 -3.7 -8.4 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3783 -3.6 -5.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3253 -3.6 -3.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3839 -3.5 -3.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4826 -3.5 -5.2 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3752 -3.4 -14.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4597 -3.4 -2.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_66 -3.4 -7.4 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3630 -3.3 -3.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3932 -3.3 -6.9 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_77 -3.3 -2.2 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_2073 -3.1 -3.7 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4278 -3.1 -10.7 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_2899 -3.1 -4.1 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_4596 -3.1 -4.1 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3251 -3.1 -9.1 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_64 -3.0 -3.4 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_5150 -3.0 -4.5 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_4277 -3.0 -14.2 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_63 -3.0 -6.0 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4825 -3.0 -4.0 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3763 -3.0 -2.0 hypothetical protein compare
Pf6N2E2_3940 -2.9 -9.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4049 -2.9 -10.5 Glycine cleavage system transcriptional activator compare
Pf6N2E2_2885 -2.8 -2.7 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_5316 -2.8 -1.9 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_3610 -2.8 -4.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3841 -2.8 -2.6 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_2897 -2.7 -7.3 Glucokinase (EC 2.7.1.2) compare
Pf6N2E2_5175 -2.7 -4.4 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_50 -2.6 -7.4 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_229 -2.6 -3.9 Putative fumarylacetoacetate (FAA) hydrolase compare
Pf6N2E2_2896 -2.5 -4.1 DNA-binding response regulator GltR, controls specific porins for the entry of glucose compare
Pf6N2E2_2074 -2.5 -1.6 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_5299 -2.5 -6.4 Benzoate transport protein compare
Pf6N2E2_4797 -2.4 -2.7 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_5014 -2.4 -1.3 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3252 -2.4 -4.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_302 -2.4 -3.0 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5257 -2.3 -9.8 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_5258 -2.3 -7.7 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_3170 -2.3 -7.6 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_3938 -2.2 -11.0 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_5666 -2.2 -9.0 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_2890 -2.1 -9.4 Glucose ABC transport system, inner membrane component 2 compare
Pf6N2E2_5176 -2.0 -2.4 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_1211 -2.0 -2.4 Lactoylglutathione lyase compare
Pf6N2E2_2518 -2.0 -3.2 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_2129 -1.9 -3.4 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_3248 -1.9 -3.0 Probable transmembrane protein compare
Pf6N2E2_2863 -1.9 -6.1 Gluconate permease compare
Pf6N2E2_2889 -1.8 -9.7 Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-) compare
Pf6N2E2_2519 -1.8 -0.9 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_2465 -1.8 -5.4 Cys regulon transcriptional activator CysB compare
Pf6N2E2_2893 -1.8 -6.0 hypothetical protein compare
Pf6N2E2_2300 -1.8 -1.8 LSU rRNA 2'-O-methyl-C2498 methyltransferase RlmM compare
Pf6N2E2_819 -1.8 -2.3 Response regulator compare
Pf6N2E2_1434 -1.8 -2.7 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) compare
Pf6N2E2_2440 -1.8 -1.8 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_2892 -1.7 -9.1 Glucose ABC transport system, periplasmic sugar-binding protein compare
Pf6N2E2_4047 -1.7 -2.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_55 -1.7 -2.0 Probable hydrolase compare
Pf6N2E2_4678 -1.6 -0.9 hypothetical protein compare
Pf6N2E2_2895 -1.6 -6.0 Integral membrane sensor signal transduction histidine kinase (EC 2.7.13.3), glucose catabolism cluster compare
Pf6N2E2_2919 -1.6 -2.5 FIG00955830: hypothetical protein compare
Pf6N2E2_3786 -1.6 -8.4 Twin-arginine translocation protein TatC compare
Pf6N2E2_2217 -1.6 -4.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_5728 -1.6 -3.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_2586 -1.6 -1.6 Hpt domain protein compare
Pf6N2E2_5667 -1.6 -6.1 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_4422 -1.5 -2.5 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
Pf6N2E2_2013 -1.5 -1.5 hypothetical protein compare
Pf6N2E2_504 -1.5 -2.7 DNA-binding response regulator compare
Pf6N2E2_5339 -1.5 -12.2 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_5990 -1.5 -1.8 Translation initiation factor 2 (IF-2; GTPase) compare
Pf6N2E2_5006 -1.5 -3.0 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3820 -1.4 -2.8 hypothetical protein compare
Pf6N2E2_4417 -1.4 -5.0 Protein of unknown function DUF484 compare
Pf6N2E2_159 -1.4 -3.1 DNA damage resistance protein (from data) compare
Pf6N2E2_4077 -1.4 -2.5 cytosolic long-chain acyl-CoA thioester hydrolase family protein compare
Pf6N2E2_5986 -1.4 -2.4 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4206 -1.4 -2.1 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_2891 -1.4 -6.8 Glucose ABC transport system, inner membrane component 1 compare
Pf6N2E2_1617 -1.4 -1.3 COG2199: FOG: GGDEF domain compare
Pf6N2E2_4579 -1.4 -0.9 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_70 -1.4 -2.8 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_1179 -1.3 -2.1 hypothetical protein compare
Pf6N2E2_2986 -1.3 -2.9 Transcriptional regulator, LuxR family compare
Pf6N2E2_4918 -1.3 -2.2 Ribonucleotide reductase transcriptional regulator NrdR compare
Pf6N2E2_51 -1.3 -5.1 hypothetical protein compare
Pf6N2E2_178 -1.3 -0.9 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_1248 -1.3 -2.9 MutT/nudix family protein compare
Pf6N2E2_2281 -1.3 -2.2 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_3826 -1.3 -3.1 Nitrogen regulation protein NR(I) compare
Pf6N2E2_5338 -1.3 -11.7 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_4276 -1.3 -4.1 Phosphogluconate repressor HexR, RpiR family compare
Pf6N2E2_5555 -1.3 -1.6 Cold shock protein CspA compare
Pf6N2E2_5545 -1.2 -2.2 Queuosine Biosynthesis QueE Radical SAM compare
Pf6N2E2_464 -1.2 -1.3 Sensory histidine kinase QseC compare
Pf6N2E2_295 -1.2 -2.1 Leucyl/phenylalanyl-tRNA--protein transferase (EC 2.3.2.6) compare
Pf6N2E2_658 -1.2 -5.8 sensor histidine kinase compare
Pf6N2E2_2984 -1.2 -1.6 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_1040 -1.2 -1.4 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_1391 -1.2 -1.6 DNA-binding response regulator, LuxR family compare
Pf6N2E2_1392 -1.2 -2.9 sensor histidine kinase compare
Pf6N2E2_5605 -1.2 -1.7 FxsA protein compare
Pf6N2E2_955 -1.2 -1.9 FIG00953508: hypothetical protein compare
Pf6N2E2_3514 -1.2 -1.6 Ribosomal protein L11 methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_5103 -1.2 -1.2 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_2675 -1.2 -0.6 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_5337 -1.2 -8.2 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_1606 -1.2 -2.5 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_2367 -1.1 -1.1 hypothetical protein compare
Pf6N2E2_3100 -1.1 -2.3 FIG00953063: hypothetical protein compare
Pf6N2E2_37 -1.1 -1.6 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_160 -1.1 -1.9 hypothetical protein compare
Pf6N2E2_5676 -1.1 -2.7 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_1715 -1.1 -2.3 hypothetical protein compare
Pf6N2E2_4351 -1.1 -7.5 Predicted signal transduction protein compare
Pf6N2E2_704 -1.1 -1.9 Cytochrome c551/c552 compare
Pf6N2E2_3611 -1.1 -1.6 HflC protein compare
Pf6N2E2_4057 -1.1 -0.6 lipoprotein, putative compare
Pf6N2E2_4423 -1.1 -1.8 FIG00953342: hypothetical protein compare
Pf6N2E2_4080 -1.1 -2.7 FIG00953722: hypothetical protein compare
Pf6N2E2_4943 -1.1 -2.1 PspA/IM30 family protein compare
Pf6N2E2_4476 -1.1 -3.1 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_3849 -1.1 -1.6 FIG00954739: hypothetical protein compare
Pf6N2E2_2022 -1.1 -0.7 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_4479 -1.1 -1.4 FIG001590: Putative conserved exported protein precursor compare
Pf6N2E2_4615 -1.1 -0.9 type IV pili signal transduction protein PilI compare
Pf6N2E2_4009 -1.1 -5.9 GGDEF domain protein compare
Pf6N2E2_4824 -1.1 -2.9 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_3933 -1.1 -4.6 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_1141 -1.1 -1.7 Lipid-A-disaccharide synthase (EC 2.4.1.182) compare
Pf6N2E2_3537 -1.0 -1.9 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_2864 -1.0 -1.6 Gluconokinase (EC 2.7.1.12) compare
Pf6N2E2_1957 -1.0 -2.3 putative inner membrane protein compare
Pf6N2E2_3908 -1.0 -2.7 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_3094 -1.0 -3.3 SAM-dependent methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_868 -1.0 -1.4 Transcriptional regulator, HxlR family compare
Pf6N2E2_3612 -1.0 -2.7 HflK protein compare
Pf6N2E2_2510 -1.0 -0.9 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_1502 -1.0 -0.7 Two-component system regulatory protein compare
Pf6N2E2_2218 -1.0 -2.2 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4331 -1.0 -2.3 hypothetical protein compare
Pf6N2E2_3009 -1.0 -2.1 Phage tail tube protein compare
Pf6N2E2_2418 -1.0 -0.8 DNA-binding response regulator, LuxR family compare
Pf6N2E2_3027 -1.0 -0.7 Baseplate assembly protein V compare
Pf6N2E2_2508 -1.0 -2.6 hypothetical protein compare
Pf6N2E2_2072 -1.0 -1.8 hypothetical protein compare
Pf6N2E2_5520 -1.0 -4.2 Sensory box histidine kinase compare
Pf6N2E2_2999 -1.0 -1.5 probable tail fiber assembly protein compare
Pf6N2E2_5974 -1.0 -2.6 Uncharacterized glutathione S-transferase-like protein compare
Pf6N2E2_3021 -1.0 -0.9 hypothetical protein compare
Pf6N2E2_4362 -0.9 -1.2 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_3201 -0.9 -1.9 Transcriptional regulator, MerR family compare
Pf6N2E2_2894 -0.9 -3.2 N-acylglucosamine 2-epimerase (EC 5.1.3.8) compare
Pf6N2E2_3106 -0.9 -2.2 hypothetical protein compare
Pf6N2E2_2496 -0.9 -1.3 FIG00956575: hypothetical protein compare
Pf6N2E2_895 -0.9 -2.2 Transcriptional regulator, HxlR family compare
Pf6N2E2_5241 -0.9 -0.8 Aminopeptidase N compare
Pf6N2E2_2552 -0.9 -6.3 Cytochrome c heme lyase subunit CcmH compare
Pf6N2E2_1325 -0.9 -1.8 FIG00954773: hypothetical protein compare
Pf6N2E2_2340 -0.9 -1.9 Transcriptional regulator, GntR family compare
Pf6N2E2_1162 -0.9 -1.5 Transmembrane amino acid efflux protein compare
Pf6N2E2_3641 -0.9 -1.7 ADP-ribose pyrophosphatase (EC 3.6.1.13) compare
Pf6N2E2_5665 -0.9 -4.4 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_3466 -0.9 -1.8 FIG000605: protein co-occurring with transport systems (COG1739) compare
Pf6N2E2_6038 -0.9 -1.4 hypothetical protein compare
Pf6N2E2_1652 -0.9 -1.4 Transcriptional regulator, TetR family compare
Pf6N2E2_16 -0.9 -1.5 hypothetical protein compare
Pf6N2E2_2488 -0.9 -1.0 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_4162 -0.9 -2.2 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_5993 -0.9 -1.1 FIG00957412: hypothetical protein compare
Pf6N2E2_1545 -0.9 -1.3 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_1932 -0.9 -1.8 Transcriptional regulator, IclR family compare
Pf6N2E2_4353 -0.9 -2.4 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_5494 -0.9 -2.3 Pyruvate kinase (EC 2.7.1.40) compare
Pf6N2E2_5877 -0.9 -1.8 Phosphohistidine phosphatase SixA compare
Pf6N2E2_469 -0.9 -0.8 lipoprotein, putative compare
Pf6N2E2_1024 -0.9 -1.8 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases compare
Pf6N2E2_4159 -0.9 -6.1 Cytochrome c4 compare
Pf6N2E2_4762 -0.9 -1.1 Biotin synthesis protein BioH compare
Pf6N2E2_3428 -0.9 -2.0 hypothetical protein compare
Pf6N2E2_3264 -0.9 -2.9 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_127 -0.9 -0.8 AttE component of AttEFGH ABC transport system compare
Pf6N2E2_3869 -0.8 -4.8 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_2124 -0.8 -1.4 Mg(2+) transport ATPase protein C compare
Pf6N2E2_3661 -0.8 -2.9 hypothetical protein compare
Pf6N2E2_74 -0.8 -1.3 DedD protein compare
Pf6N2E2_1054 -0.8 -2.6 integrase, putative compare
Pf6N2E2_3806 -0.8 -2.1 Conserved hypothetical protein (perhaps related to histidine degradation) compare


Specific Phenotypes

None in this experiment

For Pseudomonas fluorescens FW300-N2E2 in vitamin experiments