Experiment set12IT037 for Klebsiella michiganensis M5al

Compare to:

Fungal_growth_media_mCAFEs_v1 with 2,2'-Dipyridyl 50 uM

200 most important genes:

  gene name fitness t score description  
BWI76_RS01210 -4.4 -3.1 tyrosine recombinase XerC compare
BWI76_RS05835 -4.2 -5.8 gamma-glutamyl-phosphate reductase compare
BWI76_RS07070 -4.0 -7.0 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS23920 -3.9 -9.5 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS01615 -3.9 -14.4 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS20435 -3.8 -2.0 chorismate synthase compare
BWI76_RS27385 -3.6 -9.6 orotate phosphoribosyltransferase compare
BWI76_RS02995 -3.5 -10.6 aspartate carbamoyltransferase compare
BWI76_RS04160 -3.4 -7.8 phosphoserine phosphatase compare
BWI76_RS21265 -3.4 -16.0 phosphoribosylformylglycinamidine synthase compare
BWI76_RS07065 -3.3 -12.2 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS23240 -3.3 -4.9 exonuclease V subunit gamma compare
BWI76_RS01610 -3.2 -11.1 phosphoribosylamine--glycine ligase compare
BWI76_RS04470 -3.2 -9.6 carbamoyl phosphate synthase large subunit compare
BWI76_RS09660 -3.2 -2.2 DNA translocase FtsK compare
BWI76_RS09755 -3.2 -6.2 phosphoserine transaminase compare
BWI76_RS20895 -3.1 -6.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04645 -3.1 -5.8 3-dehydroquinase compare
BWI76_RS11965 -3.1 -5.1 orotidine-5'-phosphate decarboxylase compare
BWI76_RS04465 -3.0 -4.4 carbamoyl-phosphate synthase small subunit compare
BWI76_RS20965 -3.0 -8.0 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS09910 -3.0 -15.5 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS10990 -2.9 -5.1 dihydroorotase compare
BWI76_RS23365 -2.8 -7.4 LysR family transcriptional regulator compare
BWI76_RS20350 -2.7 -5.6 amidophosphoribosyltransferase compare
BWI76_RS00400 -2.7 -2.4 glutamine synthetase compare
BWI76_RS22755 -2.7 -8.0 phosphoadenosine phosphosulfate reductase compare
BWI76_RS23230 -2.6 -4.8 exodeoxyribonuclease V subunit beta compare
BWI76_RS20355 -2.6 -4.3 colicin V production protein compare
BWI76_RS18950 -2.5 -6.1 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS09760 -2.4 -5.6 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS25425 -2.4 -3.2 arginine repressor compare
BWI76_RS00990 -2.4 -11.1 ketol-acid reductoisomerase compare
BWI76_RS25645 -2.4 -8.7 shikimate dehydrogenase compare
BWI76_RS22765 -2.2 -8.5 sulfite reductase subunit alpha compare
BWI76_RS22760 -2.2 -8.0 sulfite reductase subunit beta compare
BWI76_RS02735 -2.2 -3.8 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS04255 -2.2 -10.1 threonine synthase compare
BWI76_RS27390 -2.1 -4.3 ribonuclease PH compare
BWI76_RS26085 -2.1 -2.4 3-dehydroquinate synthase compare
BWI76_RS18925 -2.0 -5.9 histidinol dehydrogenase compare
BWI76_RS00975 -2.0 -8.5 dihydroxy-acid dehydratase compare
BWI76_RS25115 -2.0 -7.1 argininosuccinate synthase compare
BWI76_RS18955 -2.0 -5.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS18935 -2.0 -7.8 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS05840 -2.0 -5.9 glutamate 5-kinase compare
BWI76_RS23265 -1.9 -3.3 hypothetical protein compare
BWI76_RS16895 -1.9 -2.9 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS00855 -1.9 -10.2 argininosuccinate lyase compare
BWI76_RS00835 -1.9 -9.7 phosphoenolpyruvate carboxylase compare
BWI76_RS18940 -1.8 -7.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS17720 -1.8 -1.4 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS15825 -1.8 -1.4 hypothetical protein compare
BWI76_RS18920 -1.8 -2.4 ATP phosphoribosyltransferase compare
BWI76_RS04510 -1.8 -2.2 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS04250 -1.7 -6.2 homoserine kinase compare
BWI76_RS00965 -1.7 -1.6 acetolactate synthase 2 small subunit compare
BWI76_RS27430 -1.7 -1.5 (p)ppGpp synthetase compare
BWI76_RS23360 -1.7 -2.3 diaminopimelate decarboxylase compare
BWI76_RS21475 -1.7 -6.2 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04305 -1.7 -1.4 molecular chaperone DnaJ compare
BWI76_RS18930 -1.6 -3.1 histidinol-phosphate transaminase compare
BWI76_RS01330 -1.6 -4.2 twin-arginine translocase subunit TatC compare
BWI76_RS03010 -1.6 -7.7 ornithine carbamoyltransferase compare
BWI76_RS23220 -1.6 -6.6 amino-acid N-acetyltransferase compare
BWI76_RS20380 -1.5 -1.7 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS22690 -1.5 -3.9 adenylyl-sulfate kinase compare
BWI76_RS09645 -1.5 -1.3 thioredoxin-disulfide reductase compare
BWI76_RS04245 -1.5 -9.1 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS00850 -1.5 -10.1 acetylglutamate kinase compare
BWI76_RS00140 -1.4 -1.3 phosphate transport system regulator PhoU compare
BWI76_RS00845 -1.4 -7.2 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS04525 -1.4 -2.6 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS17190 -1.4 -3.6 TonB system transport protein TonB compare
BWI76_RS02530 -1.4 -2.3 tRNA dimethylallyltransferase compare
BWI76_RS00355 -1.4 -2.2 DNA polymerase I compare
BWI76_RS21480 -1.4 -6.8 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS20650 -1.3 -2.5 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS25600 -1.3 -1.4 tRNA-Thr compare
BWI76_RS00805 -1.3 -3.3 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04530 -1.3 -1.6 peptidylprolyl isomerase SurA compare
BWI76_RS00980 -1.3 -7.7 PLP-dependent threonine dehydratase compare
BWI76_RS24885 -1.2 -1.9 PTS galactitol transporter subunit IIB compare
BWI76_RS00345 -1.2 -3.3 protein disulfide oxidoreductase DsbA compare
BWI76_RS26055 -1.2 -6.1 siroheme synthase compare
BWI76_RS26000 -1.2 -7.3 aspartate aminotransferase family protein compare
BWI76_RS15215 -1.2 -1.3 N-acetyltransferase compare
BWI76_RS04680 -1.2 -7.6 2-isopropylmalate synthase compare
BWI76_RS24285 -1.1 -5.2 cystathionine beta-lyase compare
BWI76_RS12090 -1.1 -1.9 HNH endonuclease compare
BWI76_RS19025 -1.1 -7.6 phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) compare
BWI76_RS20150 -1.1 -2.3 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS23480 -1.1 -5.7 EAL domain-containing protein compare
BWI76_RS22805 -1.1 -5.7 GTP diphosphokinase compare
BWI76_RS20995 -1.0 -4.1 RNA degradosome polyphosphate kinase compare
BWI76_RS06200 -1.0 -2.5 hypothetical protein compare
BWI76_RS00180 -1.0 -1.6 F0F1 ATP synthase subunit epsilon compare
BWI76_RS17975 -1.0 -3.2 tail-specific protease compare
BWI76_RS04240 -1.0 -2.8 thr operon leader peptide compare
BWI76_RS03105 -1.0 -1.2 myo-inosose-2 dehydratase compare
BWI76_RS00390 -1.0 -3.6 two-component system sensor histidine kinase NtrB compare
BWI76_RS01350 -1.0 -1.0 NAD(P)H-flavin reductase compare
BWI76_RS19685 -1.0 -5.5 lysine transporter compare
BWI76_RS15845 -1.0 -1.0 hypothetical protein compare
BWI76_RS04665 -1.0 -7.8 3-isopropylmalate dehydratase small subunit compare
BWI76_RS21345 -1.0 -2.3 sigma-E factor regulatory protein RseB compare
BWI76_RS21140 -1.0 -1.3 molecular chaperone HscA compare
BWI76_RS21075 -0.9 -1.3 membrane protein compare
BWI76_RS25065 -0.9 -2.3 polyribonucleotide nucleotidyltransferase compare
BWI76_RS00960 -0.9 -5.7 acetolactate synthase 2 catalytic subunit compare
BWI76_RS18385 -0.9 -1.3 hypothetical protein compare
BWI76_RS04670 -0.9 -4.9 3-isopropylmalate dehydratase large subunit compare
BWI76_RS24180 -0.9 -2.1 hypothetical protein compare
BWI76_RS01200 -0.9 -1.6 diaminopimelate epimerase compare
BWI76_RS04675 -0.9 -3.7 3-isopropylmalate dehydrogenase compare
BWI76_RS09655 -0.9 -3.2 leucine-responsive regulatory protein compare
BWI76_RS07725 -0.9 -1.2 iron-enterobactin transporter permease compare
BWI76_RS12985 -0.9 -1.5 transcriptional regulator compare
BWI76_RS06765 -0.9 -2.5 transcriptional regulator compare
BWI76_RS14065 -0.9 -1.7 hypothetical protein compare
BWI76_RS16090 -0.9 -1.4 two-component system response regulator DcuR compare
BWI76_RS23930 -0.9 -4.3 transcriptional regulator ArgP compare
BWI76_RS19050 -0.8 -5.6 NAD(P)-dependent oxidoreductase compare
BWI76_RS25335 -0.8 -1.2 stringent starvation protein A compare
BWI76_RS26620 -0.8 -1.1 Fe-S biogenesis protein NfuA compare
BWI76_RS27440 -0.8 -3.1 DNA helicase RecG compare
BWI76_RS01385 -0.8 -1.6 potassium transporter compare
BWI76_RS20440 -0.8 -1.6 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS19690 -0.8 -1.7 LysR family transcriptional regulator compare
BWI76_RS24900 -0.8 -1.1 DeoR family transcriptional regulator compare
BWI76_RS26570 -0.8 -2.6 anion permease compare
BWI76_RS04270 -0.8 -3.6 transaldolase compare
BWI76_RS06080 -0.8 -1.7 taurine dioxygenase compare
BWI76_RS05465 -0.8 -1.1 amidohydrolase compare
BWI76_RS04685 -0.8 -4.4 putative leucine operon leader peptide compare
BWI76_RS09635 -0.8 -1.9 amino acid ABC transporter ATP-binding protein compare
BWI76_RS17980 -0.8 -2.3 RNA chaperone ProQ compare
BWI76_RS27305 -0.8 -3.5 glycosyl transferase compare
BWI76_RS08520 -0.8 -0.9 colicin transporter TolQ compare
BWI76_RS08535 -0.7 -1.0 translocation protein TolB compare
BWI76_RS04715 -0.7 -0.8 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS02610 -0.7 -3.2 transcriptional regulator compare
BWI76_RS01275 -0.7 -2.8 LysR family transcriptional regulator compare
BWI76_RS26395 -0.7 -3.0 cell division protein FtsE compare
BWI76_RS11040 -0.7 -2.6 ribonuclease E compare
BWI76_RS20640 -0.7 -2.6 cysteine synthase A compare
BWI76_RS12070 -0.7 -0.9 hypothetical protein compare
BWI76_RS14625 -0.7 -1.0 protein TolA compare
BWI76_RS22735 -0.7 -3.0 type I-E CRISPR-associated protein Cas7/Cse4/CasC compare
BWI76_RS01655 -0.7 -2.7 homoserine O-succinyltransferase compare
BWI76_RS11345 -0.7 -3.0 LysR family transcriptional regulator compare
BWI76_RS27425 -0.7 -1.9 DNA-directed RNA polymerase subunit omega compare
BWI76_RS08605 -0.7 -2.0 phosphoglyceromutase compare
BWI76_RS14075 -0.7 -0.7 TetR family transcriptional regulator compare
BWI76_RS19865 -0.7 -1.4 ecotin compare
BWI76_RS06015 -0.7 -1.3 hypothetical protein compare
BWI76_RS25220 -0.7 -2.7 outer membrane lipid asymmetry maintenance protein MlaD compare
BWI76_RS21370 -0.7 -1.1 ATP-dependent RNA helicase SrmB compare
BWI76_RS15290 -0.7 -1.0 transcriptional regulator compare
BWI76_RS21870 -0.7 -2.9 hypothetical protein compare
BWI76_RS15350 -0.7 -0.9 hypothetical protein compare
BWI76_RS19055 -0.7 -3.9 dTDP-4-dehydrorhamnose 3,5-epimerase compare
BWI76_RS19000 -0.7 -2.7 acyltransferase compare
BWI76_RS01280 -0.7 -4.0 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase compare
BWI76_RS25505 -0.7 -3.7 RNase E specificity factor CsrD compare
BWI76_RS12340 -0.7 -2.7 molecular chaperone Tir compare
BWI76_RS18430 -0.7 -1.3 hypothetical protein compare
BWI76_RS22130 -0.7 -1.4 fructose-1-phosphate/6-phosphogluconate phosphatase compare
BWI76_RS09650 -0.7 -2.6 hypothetical protein compare
BWI76_RS27780 -0.7 -1.4 hypothetical protein compare
BWI76_RS04985 -0.7 -1.2 aspartate 1-decarboxylase compare
BWI76_RS24120 -0.6 -2.2 YggW family oxidoreductase compare
BWI76_RS05005 -0.6 -1.8 polynucleotide adenylyltransferase compare
BWI76_RS26635 -0.6 -1.5 hypothetical protein compare
BWI76_RS26665 -0.6 -2.0 DNA-binding response regulator compare
BWI76_RS00970 -0.6 -1.8 branched chain amino acid aminotransferase compare
BWI76_RS23340 -0.6 -1.6 transcriptional regulator compare
BWI76_RS16195 -0.6 -1.2 hypothetical protein compare
BWI76_RS19330 -0.6 -0.8 HAD family hydrolase compare
BWI76_RS06735 -0.6 -1.4 50S ribosomal protein L31 compare
BWI76_RS26390 -0.6 -2.1 cell division protein FtsX compare
BWI76_RS12790 -0.6 -1.0 lactate dehydrogenase compare
BWI76_RS00785 -0.6 -3.6 cystathionine gamma-synthase compare
BWI76_RS08385 -0.6 -1.5 citrate (Si)-synthase compare
BWI76_RS05450 -0.6 -1.0 ribonuclease HI compare
BWI76_RS13250 -0.6 -0.8 cytochrome b561 compare
BWI76_RS08260 -0.6 -1.9 LysR family transcriptional regulator compare
BWI76_RS17400 -0.6 -0.8 transporter compare
BWI76_RS07705 -0.6 -1.5 enterochelin esterase compare
BWI76_RS01185 -0.6 -1.6 adenylate cyclase compare
BWI76_RS03595 -0.6 -1.0 ethanolamine utilization protein EutM compare
BWI76_RS05015 -0.6 -1.3 transcriptional regulator compare
BWI76_RS06130 -0.6 -0.7 extensin family protein compare
BWI76_RS11840 -0.6 -1.7 tryptophan synthase subunit alpha compare
BWI76_RS13980 -0.6 -1.0 hypothetical protein compare
BWI76_RS05555 -0.6 -1.5 Crl family RNA polymerase assembly factor compare
BWI76_RS17675 -0.6 -1.3 hypothetical protein compare
BWI76_RS24600 -0.6 -2.0 dihydroxyacetone kinase compare
BWI76_RS20695 -0.6 -1.9 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS11835 -0.6 -0.8 putative regulatory protein MarR compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in stress experiments

For stress 2,2'-Dipyridyl across organisms