Experiment set12IT034 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_glucose with 2,2'-Dipyridyl 400 uM

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS19770 +1.0 2.2 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS16025 +1.0 2.0 triphosphoribosyl-dephospho-CoA synthase compare
BWI76_RS11775 +0.9 3.7 2-deoxy-D-gluconate 3-dehydrogenase compare
BWI76_RS07475 +0.8 1.5 DNA-binding transcriptional regulator RamA compare
BWI76_RS06680 +0.8 1.4 hypothetical protein compare
BWI76_RS12070 +0.8 1.5 hypothetical protein compare
BWI76_RS09730 +0.8 2.0 pyruvate formate lyase 1-activating protein compare
BWI76_RS18605 +0.8 1.5 oxidoreductase molybdopterin-binding protein compare
BWI76_RS11700 +0.8 1.5 hypothetical protein compare
BWI76_RS02180 +0.8 1.7 hypothetical protein compare
BWI76_RS20785 +0.8 1.6 ethanolamine utilization protein EutJ compare
BWI76_RS18125 +0.7 2.9 murein DD-endopeptidase MepM compare
BWI76_RS23015 +0.7 1.8 cobalt transporter ATP-binding subunit compare
BWI76_RS19935 +0.7 1.9 hypothetical protein compare
BWI76_RS11635 +0.7 2.0 ABC transporter compare
BWI76_RS15975 +0.7 1.3 hypothetical protein compare
BWI76_RS20390 +0.7 2.5 erythronate-4-phosphate dehydrogenase compare
BWI76_RS17470 +0.7 1.6 MerR family transcriptional regulator compare
BWI76_RS16935 +0.7 1.3 shikimate dehydrogenase compare
BWI76_RS23020 +0.7 1.4 cobalamin biosynthesis protein CbiQ compare
BWI76_RS18225 +0.7 2.9 universal stress protein C compare
BWI76_RS07285 +0.6 2.6 LysR family transcriptional regulator compare
BWI76_RS13240 +0.6 1.4 hypothetical protein compare
BWI76_RS03045 +0.6 1.3 hypothetical protein compare
BWI76_RS19865 +0.6 2.1 ecotin compare
BWI76_RS01545 +0.6 1.9 thiamine biosynthesis protein ThiS compare
BWI76_RS24080 +0.6 1.6 DUF179 domain-containing protein compare
BWI76_RS25630 +0.6 2.8 hypothetical protein compare
BWI76_RS26630 +0.6 2.3 pimeloyl-[acyl-carrier protein] methyl ester esterase compare
BWI76_RS21140 +0.6 1.5 molecular chaperone HscA compare
BWI76_RS11520 +0.6 1.1 hypothetical protein compare
BWI76_RS16510 +0.6 2.8 transcriptional repressor PurR compare
BWI76_RS21235 +0.6 1.2 hypothetical protein compare
BWI76_RS24825 +0.6 2.2 2-hydroxy-3-oxopropionate reductase compare
BWI76_RS06370 +0.6 1.5 phosphatidylglycerophosphatase A compare
BWI76_RS23960 +0.6 3.1 oxidative stress defense protein compare
BWI76_RS00795 +0.6 1.9 carboxymuconolactone decarboxylase compare
BWI76_RS05465 +0.6 1.2 amidohydrolase compare
BWI76_RS10655 +0.6 2.4 [formate-C-acetyltransferase]-activating enzyme compare
BWI76_RS23355 +0.6 2.1 LacI family transcriptional regulator compare
BWI76_RS06665 +0.6 1.0 membrane protein compare
BWI76_RS19700 +0.5 1.2 deoxyribonuclease IV compare
BWI76_RS09325 +0.5 2.4 putative bacteriophage tail completion protein compare
BWI76_RS22840 +0.5 1.5 transposase compare
BWI76_RS01190 +0.5 1.1 iron donor protein CyaY compare
BWI76_RS07995 +0.5 0.9 twin-arginine translocase subunit TatA compare
BWI76_RS06895 +0.5 2.0 biopolymer transporter ExbB compare
BWI76_RS07510 +0.5 2.1 hypothetical protein compare
BWI76_RS04655 +0.5 1.6 shikimate dehydrogenase compare
BWI76_RS18885 +0.5 1.6 nitrogen fixation regulatory protein compare
BWI76_RS16955 +0.5 0.9 hypothetical protein compare
BWI76_RS15015 +0.5 1.1 DUF2132 domain-containing protein compare
BWI76_RS18240 +0.5 1.5 L-arabinose ABC transporter permease AraH compare
BWI76_RS21715 +0.5 1.7 transcriptional regulator compare
BWI76_RS22205 +0.5 1.5 cation ABC transporter ATP-binding protein compare
BWI76_RS12470 +0.5 1.3 thiosulfate sulfurtransferase PspE compare
BWI76_RS16455 +0.5 1.5 superoxide dismutase compare
BWI76_RS22185 +0.5 1.3 hypothetical protein compare
BWI76_RS01540 +0.5 0.9 thiamine biosynthesis protein ThiS compare
BWI76_RS24040 +0.5 1.8 hypothetical protein compare
BWI76_RS09115 +0.5 1.2 30S ribosomal protein S12 methylthiotransferase RimO compare
BWI76_RS09280 +0.5 2.2 terminase endonuclease subunit compare
BWI76_RS26890 +0.5 0.5 hypothetical protein compare
BWI76_RS26095 +0.5 0.7 shikimate kinase compare
BWI76_RS08855 +0.5 1.3 endonuclease/exonuclease/phosphatase compare
BWI76_RS19670 +0.5 1.9 S-formylglutathione hydrolase compare
BWI76_RS20730 +0.5 1.2 hypothetical protein compare
BWI76_RS09290 +0.5 1.3 phage Tail Protein X compare
BWI76_RS06505 +0.5 2.8 hypothetical protein compare
BWI76_RS20085 +0.5 1.6 GNAT family N-acetyltransferase compare
BWI76_RS15205 +0.5 1.8 succinate-semialdehyde dehydrogenase compare
BWI76_RS16740 +0.5 2.0 transcriptional regulator compare
BWI76_RS18870 +0.5 1.0 protein NifZ compare
BWI76_RS13130 +0.5 1.6 phenylacetic acid degradation protein PaaD compare
BWI76_RS07595 +0.5 1.4 putative oxidoreductase compare
BWI76_RS05135 +0.5 1.1 iron-hydroxamate transporter substrate-binding subunit compare
BWI76_RS12390 +0.5 1.6 antibiotic biosynthesis monooxygenase compare
BWI76_RS16300 +0.5 1.1 bifunctional beta-cystathionase/maltose regulon regulatory protein compare
BWI76_RS03080 +0.5 1.1 (Fe-S)-cluster assembly protein compare
BWI76_RS22095 +0.5 1.8 multidrug export protein EmrA compare
BWI76_RS01775 +0.5 0.8 hypothetical protein compare
BWI76_RS13425 +0.5 2.9 1-pyrroline dehydrogenase compare
BWI76_RS21810 +0.5 1.2 universal stress protein compare
BWI76_RS10870 +0.5 2.8 nicotinamidase compare
BWI76_RS24150 +0.5 1.9 tRNA (guanosine(46)-N7)-methyltransferase TrmB compare
BWI76_RS15150 +0.5 2.4 outer membrane efflux protein compare
BWI76_RS23820 +0.5 1.0 flavodoxin FldB compare
BWI76_RS02920 +0.4 1.7 addiction module toxin RelE compare
BWI76_RS18815 +0.4 1.0 nitrogenase molybdenum-iron protein alpha chain compare
BWI76_RS12910 +0.4 2.3 3,4-dihydroxyphenylacetate 2,3-dioxygenase compare
BWI76_RS18385 +0.4 0.9 hypothetical protein compare
BWI76_RS27820 +0.4 1.0 ilvB operon leader peptide IvbL compare
BWI76_RS26295 +0.4 2.8 glycerol-3-phosphate transporter membrane protein compare
BWI76_RS06810 +0.4 2.0 hypothetical protein compare
BWI76_RS06520 +0.4 1.9 trigger factor compare
BWI76_RS00800 +0.4 2.7 LysR family transcriptional regulator compare
BWI76_RS22960 +0.4 1.6 YgdI/YgdR family lipoprotein compare
BWI76_RS13575 +0.4 2.0 sugar binding transcriptional regulator, LacI family protein compare
BWI76_RS23125 +0.4 1.3 propanediol dehydratase small subunit compare
BWI76_RS12965 +0.4 2.3 LysR family transcriptional regulator compare
BWI76_RS02870 +0.4 1.4 hypothetical protein compare
BWI76_RS18810 +0.4 1.8 nitrogenase iron protein compare
BWI76_RS26525 +0.4 1.7 nickel-responsive transcriptional regulator NikR compare
BWI76_RS20890 +0.4 1.6 neutral zinc metallopeptidase compare
BWI76_RS24575 +0.4 0.9 hypothetical protein compare
BWI76_RS15190 +0.4 1.8 GGDEF domain-containing protein compare
BWI76_RS17330 +0.4 1.4 nitrate reductase subunit beta compare
BWI76_RS05800 +0.4 1.4 phage transcriptional activator, Ogr/delta compare
BWI76_RS15890 +0.4 2.3 Zn-dependent oxidoreductase compare
BWI76_RS27770 +0.4 1.4 hypothetical protein compare
BWI76_RS11170 +0.4 0.8 hypothetical protein compare
BWI76_RS25000 +0.4 0.6 malonate decarboxylase acyl carrier protein compare
BWI76_RS15260 +0.4 1.1 hypothetical protein compare
BWI76_RS16350 +0.4 2.2 membrane protein compare
BWI76_RS19960 +0.4 2.3 MFS transporter compare
BWI76_RS19585 +0.4 0.9 gentisate 1,2-dioxygenase compare
BWI76_RS24250 +0.4 1.6 hypothetical protein compare
BWI76_RS19490 +0.4 2.3 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS12580 +0.4 1.5 oxidoreductase compare
BWI76_RS27875 +0.4 0.8 membrane protein compare
BWI76_RS13290 +0.4 2.0 protocatechuate 3,4-dioxygenase subunit beta compare
BWI76_RS17920 +0.4 1.2 23S rRNA (guanine(745)-N(1))-methyltransferase compare
BWI76_RS08375 +0.4 0.9 pyroglutamyl-peptidase I compare
BWI76_RS23900 +0.4 1.7 hypothetical protein compare
BWI76_RS08405 +0.4 1.3 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS26780 +0.4 2.8 cellulose synthase regulator BcsB compare
BWI76_RS14245 +0.4 1.5 carboxymuconolactone decarboxylase family protein compare
BWI76_RS05425 +0.4 2.2 EEP domain-containing protein compare
BWI76_RS14650 +0.4 1.0 helix-turn-helix transcriptional regulator compare
BWI76_RS14170 +0.4 1.2 hypothetical protein compare
BWI76_RS07305 +0.4 2.0 sucrose operon repressor compare
BWI76_RS00560 +0.4 1.1 hypothetical protein compare
BWI76_RS17300 +0.4 0.7 tRNA-Tyr compare
BWI76_RS01835 +0.4 1.6 chemotaxis protein CheW compare
BWI76_RS00880 +0.4 1.8 membrane protein compare
BWI76_RS17320 +0.4 1.8 respiratory nitrate reductase subunit gamma compare
BWI76_RS19750 +0.4 1.8 elongation factor P-like protein YeiP compare
BWI76_RS13685 +0.4 1.0 IclR family transcriptional regulator compare
BWI76_RS17405 +0.4 1.6 cation transport regulator compare
BWI76_RS10815 +0.4 1.5 iron permease compare
BWI76_RS21445 +0.4 1.9 hypothetical protein compare
BWI76_RS18390 +0.4 1.5 hypothetical protein compare
BWI76_RS16195 +0.4 0.9 hypothetical protein compare
BWI76_RS21675 +0.4 0.9 hypothetical protein compare
BWI76_RS24610 +0.4 2.1 dihydroxyacetone kinase compare
BWI76_RS10760 +0.4 0.8 nitroreductase family protein compare
BWI76_RS23030 +0.4 1.1 cobalamin biosynthesis protein CbiM compare
BWI76_RS23390 +0.4 2.0 oligogalacturonide ABC transporter ATP-binding protein compare
BWI76_RS01185 +0.4 0.8 adenylate cyclase compare
BWI76_RS23705 +0.4 1.7 2-deoxy-D-ribonyl-CoA 3-dehydrogenase (from data) compare
BWI76_RS21895 +0.4 2.0 amino acid ABC transport system periplasmic amino acid-binding component compare
BWI76_RS12800 +0.4 1.9 hypothetical protein compare
BWI76_RS02655 +0.4 1.1 hypothetical protein compare
BWI76_RS05790 +0.4 0.9 phage DNA-binding protein compare
BWI76_RS20025 +0.4 1.7 HAMP domain-containing histidine kinase compare
BWI76_RS15075 +0.4 1.7 non-ribosomal peptide synthase compare
BWI76_RS11735 +0.4 1.3 PTS N,N'-diacetylchitobiose transporter subunit IIA compare
BWI76_RS01335 +0.4 1.2 DNase TatD compare
BWI76_RS10575 +0.4 0.7 polar amino acid ABC transporter permease compare
BWI76_RS16175 +0.4 1.2 p-aminobenzoyl-glutamate transporter compare
BWI76_RS12515 +0.4 1.4 protease compare
BWI76_RS18615 +0.4 2.1 glutathione S-transferase domain protein compare
BWI76_RS01035 +0.4 1.2 ADP-ribosylation/crystallin J1 compare
BWI76_RS24955 +0.4 1.0 hypothetical protein compare
BWI76_RS08510 +0.4 0.8 cyd operon protein YbgE compare
BWI76_RS22290 +0.4 2.0 PTS cellobiose/arbutin/salicin transporter subunit IIBC compare
BWI76_RS13525 +0.4 1.6 putative luciferase-like monooxygenase compare
BWI76_RS05190 +0.4 2.1 hypothetical protein compare
BWI76_RS08800 +0.4 2.2 phosphoethanolamine transferase EptA compare
BWI76_RS11665 +0.4 1.4 exodeoxyribonuclease III compare
BWI76_RS11135 +0.4 2.4 ferric-rhodotorulic acid/ferric-coprogen receptor FhuE compare
BWI76_RS06075 +0.4 1.3 taurine transporter subunit compare
BWI76_RS07855 +0.4 1.4 PucR family transcriptional regulator compare
BWI76_RS14755 +0.4 1.1 SIS domain-containing protein compare
BWI76_RS17655 +0.4 1.2 MFS transporter compare
BWI76_RS11805 +0.4 1.9 hypothetical protein compare
BWI76_RS16875 +0.4 2.1 putative type I cysteine dioxygenase compare
BWI76_RS22900 +0.4 1.9 alkanesulfonate monooxygenase compare
BWI76_RS09765 +0.4 1.1 metalloprotease compare
BWI76_RS17310 +0.4 1.1 AsnC family transcriptional regulator compare
BWI76_RS15435 +0.4 0.8 hypothetical protein compare
BWI76_RS26260 +0.4 1.8 hypothetical protein compare
BWI76_RS16645 +0.4 1.1 DeoR family transcriptional regulator compare
BWI76_RS23945 +0.3 1.7 methylmalonyl-CoA decarboxylase compare
BWI76_RS10675 +0.3 2.4 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS02420 +0.3 1.6 entericidin EcnAB compare
BWI76_RS13800 +0.3 1.7 zinc-dependent alcohol dehydrogenase compare
BWI76_RS02265 +0.3 0.9 putative transmembrane protein compare
BWI76_RS22820 +0.3 1.6 glycerate kinase compare
BWI76_RS10070 +0.3 1.6 BAX inhibitor protein compare
BWI76_RS06420 +0.3 1.9 oxidoreductase compare
BWI76_RS16655 +0.3 1.0 CatA-like O-acetyltransferase compare
BWI76_RS01560 +0.3 1.3 Rsd/AlgQ family anti-sigma factor compare
BWI76_RS26450 +0.3 2.0 hypothetical protein compare
BWI76_RS01650 +0.3 1.3 acetyltransferase compare
BWI76_RS26785 +0.3 2.4 UDP-forming cellulose synthase catalytic subunit compare
BWI76_RS04200 +0.3 1.1 phosphoglycerate mutase GpmB compare
BWI76_RS27345 +0.3 1.6 hypothetical protein compare
BWI76_RS04445 +0.3 1.8 citrate (pro-3S)-lyase subunit beta compare
BWI76_RS09610 +0.3 1.4 ATP-dependent Clp protease adaptor ClpS compare


Specific Phenotypes

For 1 genes in this experiment

For stress 2,2'-Dipyridyl in Klebsiella michiganensis M5al

For stress 2,2'-Dipyridyl across organisms